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Items: 1 to 20 of 22

1.
Roles of the M4 Acetylcholine Receptor in the Basal Ganglia and the Treatment of Movement Disorders
M.S. Moehle, P.J. Conn
Mov Disord. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Mov Disord. 2019 Aug; 34(8): 1089–1099. Published online 2019 Jun 18. doi: 10.1002/mds.27740
PMCID:
PMC6699902
AbstractArticlePDF–696K
2.
African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction
Orna Levran, Matthew Randesi, Einat Peles, Joel Correa da Rosa, Jurg Ott, John Rotrosen, Miriam Adelson, Mary Jeanne Kreek
Pharmacogenomics. 2016 Jun; 17(9): 995–1003. Published online 2016 Jun 7. doi: 10.2217/pgs-2016-0028
PMCID:
PMC4996315
AbstractArticlePDF–1018K
3.
Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus→midbrain pathway for feeding behavior
Tevye J. Stachniak, Anirvan Ghosh, Scott M. Sternson
Neuron. Author manuscript; available in PMC 2015 Jan 26.
Published in final edited form as: Neuron. 2014 May 21; 82(4): 797–808. Published online 2014 Apr 24. doi: 10.1016/j.neuron.2014.04.008
PMCID:
PMC4306349
AbstractArticlePDF–4.9M
4.
Structural Determinants of Allosteric Agonism and Modulation at the M4 Muscarinic Acetylcholine Receptor: IDENTIFICATION OF LIGAND-SPECIFIC AND GLOBAL ACTIVATION MECHANISMS
Vindhya Nawaratne, Katie Leach, Christian C. Felder, Patrick M. Sexton, Arthur Christopoulos
J Biol Chem. 2010 Jun 18; 285(25): 19012–19021. Published online 2010 Apr 20. doi: 10.1074/jbc.M110.125096
PMCID:
PMC2885178
AbstractArticlePDF–1.4M
5.
An SstI polymorphism for the human muscarinic acetylcholine receptor gene, m4 (CHRM 4).
S D Detera-Wadleigh, D Wiesch, T I Bonner
Nucleic Acids Res. 1989 Aug 11; 17(15): 6431. doi: 10.1093/nar/17.15.6431
PMCID:
PMC318330
SummaryPage BrowsePDF–54K
6.
Crystal Structures of the M1 and M4 Muscarinic Acetylcholine Receptors
David M. Thal, Bingfa Sun, Dan Feng, Vindhya Nawaratne, Katie Leach, Christian C. Felder, Mark G. Bures, David A. Evans, William I. Weis, Priti Bachhawat, Tong Sun Kobilka, Patrick M. Sexton, Brian K. Kobilka, Arthur Christopoulos
Nature. Author manuscript; available in PMC 2016 Sep 17.
Published in final edited form as: Nature. 2016 Mar 17; 531(7594): 335–340. Published online 2016 Mar 9. doi: 10.1038/nature17188
PMCID:
PMC4915387
AbstractArticlePDF–1.9M
7.
Nerve growth factor interacts with CHRM4 and promotes neuroendocrine differentiation of prostate cancer and castration resistance
Wei-Yu Chen, Yu-Ching Wen, Shian-Ren Lin, Hsiu-Lien Yeh, Kuo-Ching Jiang, Wei-Hao Chen, Yow-Sien Lin, Qingfu Zhang, Phui-Ly Liew, Michael Hsiao, Jiaoti Huang, Yen-Nien Liu
Commun Biol. 2021; 4: 22. Published online 2021 Jan 4. doi: 10.1038/s42003-020-01549-1
PMCID:
PMC7782543
AbstractArticlePDF–3.1M
8.
Novel signaling pathways mediating reciprocal control of keratinocyte migration and wound epithelialization through M3 and M4 muscarinic receptors
Alex I. Chernyavsky, Juan Arredondo, Jürgen Wess, Evert Karlsson, Sergei A. Grando
J Cell Biol. 2004 Jul 19; 166(2): 261–272. doi: 10.1083/jcb.200401034
PMCID:
PMC2172302
AbstractArticlePDF–5.9M
9.
Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.
E G Peralta, A Ashkenazi, J W Winslow, D H Smith, J Ramachandran, D J Capon
EMBO J. 1987 Dec 20; 6(13): 3923–3929. doi: 10.1002/j.1460-2075.1987.tb02733.x
PMCID:
PMC553870
SummaryPage BrowsePDF–1.6M
10.
Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells
Muriel Nobles, Amy Benians, Andrew Tinker
Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51): 18706–18711. Published online 2005 Dec 13. doi: 10.1073/pnas.0504778102
PMCID:
PMC1317907
AbstractArticlePDF–736K
11.
No Evidence for Association between 19 Cholinergic Genes and Bipolar Disorder
Jiajun Shi, Eiji Hattori, Hongwei Zou, Judith A. Badner, Susan L. Christian, Elliot S. Gershon, Chunyu Liu
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2008 Oct 30.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2007 Sep 5; 144B(6): 715–723. doi: 10.1002/ajmg.b.30417
PMCID:
PMC2576477
AbstractArticlePDF–319K
12.
Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis
Anna C Need, Richard SE Keefe, Dongliang Ge, Iris Grossman, Sam Dickson, Joseph P McEvoy, David B Goldstein
Eur J Hum Genet. 2009 Jul; 17(7): 946–957. Published online 2009 Jan 21. doi: 10.1038/ejhg.2008.264
PMCID:
PMC2986499
AbstractArticlePDF–172K
13.
Genetical genomic determinants of alcohol consumption in rats and humans
Boris Tabakoff, Laura Saba, Morton Printz, Pam Flodman, Colin Hodgkinson, David Goldman, George Koob, Heather N Richardson, Katerina Kechris, Richard L Bell, Norbert Hübner, Matthias Heinig, Michal Pravenec, Jonathan Mangion, Lucie Legault, Maurice Dongier, Katherine M Conigrave, John B Whitfield, John Saunders, Bridget Grant, Paula L Hoffman, WHO/ISBRA Study on State and Trait Markers of Alcoholism
BMC Biol. 2009; 7: 70. Published online 2009 Oct 27. doi: 10.1186/1741-7007-7-70
PMCID:
PMC2777866
AbstractArticlePDF–1.0M
14.
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629
PMCID:
PMC8842165
AbstractArticlePDF–3.0M
15.
Shotgun sequencing of the human transcriptome with ORF expressed sequence tags
Emmanuel Dias Neto, Ricardo Garcia Correa, Sergio Verjovski-Almeida, Marcelo R. S. Briones, Maria Aparecida Nagai, Wilson da Silva, Jr., Marco Antonio Zago, Silvana Bordin, Fernando Ferreira Costa, Gustavo Henrique Goldman, Alex F. Carvalho, Adriana Matsukuma, Gilson S. Baia, David H. Simpson, Adriana Brunstein, Paulo S. L. de Oliveira, Philipp Bucher, C. Victor Jongeneel, Michael J. O'Hare, Fernando Soares, Ricardo R. Brentani, Luis F. L. Reis, Sandro J. de Souza, Andrew J. G. Simpson
Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7): 3491–3496. doi: 10.1073/pnas.97.7.3491
PMCID:
PMC16267
AbstractArticlePDF–111K
16.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
17.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
18.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
19.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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