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Select item 79105921.

High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy

Qing-Rui Wu, Dan-Lin Zheng, Pei-Ming Liu, Hui Yang, Lu-An Li, Su-Juan Kuang, Ying-Yu Lai, Fang Rao, Yu-Mei Xue, Ji-Jin Lin, Shuang-Xin Liu, Chun-Bo Chen, Chun-Yu Deng

Cell Death Dis. 2021 Feb; 12(2): 216. Published online 2021 Feb 26. doi: 10.1038/s41419-021-03502-4

PMCID:: PMC7910592

Abstract Article PDF–2.8M

Select item 77532002.

Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain

Bianca Patel, Lauryn E. New, Joanne C. Griffiths, Jim Deuchars, Beatrice M. Filippi

Mol Metab. 2021 Jan; 43: 101123. Published online 2020 Nov 20. doi: 10.1016/j.molmet.2020.101123

PMCID:: PMC7753200

Abstract Article PDF–3.7M

Select item 72896853.

Mitochondrial Fission Mediates Endothelial Inflammation

Steven J. Forrester, Kyle J. Preston, Hannah A. Cooper, Michael J. Boyer, Kathleen M. Escoto, Anthony J. Poltronetti, Katherine J. Elliott, Ryohei Kuroda, Masashi Miyao, Hiromi Sesaki, Tomoko Akiyama, Yayoi Kimura, Victor Rizzo, Rosario Scalia, Satoru Eguchi

Hypertension. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Hypertension. 2020 Jul; 76(1): 267–276. Published online 2020 May 11. doi: 10.1161/HYPERTENSIONAHA.120.14686

PMCID:: PMC7289685

Abstract Article PDF–2.0M

Select item 71708744.

Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Chenyang Duan, Lei Kuang, Xinming Xiang, Jie Zhang, Yu Zhu, Yue Wu, Qingguang Yan, Liangming Liu, Tao Li

Cell Death Dis. 2020 Apr; 11(4): 251. Published online 2020 Apr 20. doi: 10.1038/s41419-020-2461-9

Correction in:: Cell Death Dis. 2020 Aug; 11(8): 700.

PMCID:: PMC7170874

Abstract Article PDF–5.1M

Select item 61153945.

PDI-mediated S-nitrosylation of DRP1 facilitates DRP1-S616 phosphorylation and mitochondrial fission in CA1 neurons

Duk-shin Lee, Ji-Eun Kim

Cell Death Dis. 2018 Sep; 9(9): 869. Published online 2018 Aug 29. doi: 10.1038/s41419-018-0910-5

PMCID:: PMC6115394

Abstract Article PDF–2.3M

Select item 49655466.

Swati Agarwal, Anuradha Yadav, Shashi Kant Tiwari, Brashket Seth, Lalit Kumar Singh Chauhan, Puneet Khare, Ratan Singh Ray, Rajnish Kumar Chaturvedi

J Biol Chem. 2016 Jul 29; 291(31): 15923–15939. Published online 2016 Jun 1. doi: 10.1074/jbc.M115.709493

Correction in:: J Biol Chem. 2020 Feb 28; 295(9): 2887.

PMCID:: PMC4965546

Abstract Article PDF–4.2M

Select item 38683487.

Nitrite activates protein kinase A in normoxia to mediate mitochondrial fusion and tolerance to ischaemia/reperfusion

Christelle Kamga Pride, Li Mo, Kelly Quesnelle, Ruben K. Dagda, Daniel Murillo, Lisa Geary, Catherine Corey, Rafael Portella, Sergey Zharikov, Claudette St Croix, Salony Maniar, Charleen T. Chu, Nicholas K. H. Khoo, Sruti Shiva

Cardiovasc Res. 2014 Jan 1; 101(1): 57–68. Published online 2013 Sep 30. doi: 10.1093/cvr/cvt224

PMCID:: PMC3868348

Abstract Article PDF–1.2M

Select item 37022848.

Alterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission

M Sarin, Y Wang, F Zhang, K Rothermund, Y Zhang, J Lu, S Sims-Lucas, D Beer-Stolz, B E Van Houten, J Vockley, E S Goetzman, J Anthony Graves, E V Prochownik

Cell Death Dis. 2013 Jun; 4(6): e670. Published online 2013 Jun. doi: 10.1038/cddis.2013.201

PMCID:: PMC3702284

Abstract Article PDF–2.0M

Select item 36369199.

A Calcineurin Docking Motif (LXVP) in Dynamin-related Protein 1 Contributes to Mitochondrial Fragmentation and Ischemic Neuronal Injury

Andrew M. Slupe, Ronald A. Merrill, Kyle H. Flippo, Mark A. Lobas, Jon C. D. Houtman, Stefan Strack

J Biol Chem. 2013 Apr 26; 288(17): 12353–12365. Published online 2013 Mar 13. doi: 10.1074/jbc.M113.459677

PMCID:: PMC3636919

Abstract Article PDF–2.0M

Select item 349815910.

Involvement of Dynamin-Related Protein 1 in Free Fatty Acid-Induced INS-1-Derived Cell Apoptosis

Liang Peng, Xiuli Men, Wenjian Zhang, Haiyan Wang, Shiqing Xu, Qing Fang, Honglin Liu, Wenying Yang, Jinning Lou

PLoS One. 2012; 7(11): e49258. Published online 2012 Nov 14. doi: 10.1371/journal.pone.0049258

Correction in:: PLoS One. 2013; 8(8): 10.1371/annotation/831aa38a-a30b-4d47-a4b3-10f5b0709158.

Correction in:: PLoS One. 2013; 8(9): 10.1371/annotation/f8ab435d-accb-4383-8784-23e6edf82f56.

PMCID:: PMC3498159

Abstract Article PDF–4.3M

Select item 315724511.

Role of Drp1, a Key Mitochondrial Fission Protein, in Neuropathic Pain

Luiz F. Ferrari, Adrienne Chum, Oliver Bogen, David B. Reichling, Jon D. Levine

J Neurosci. 2011 Aug 3; 31(31): 11404–11410. doi: 10.1523/JNEUROSCI.2223-11.2011

PMCID:: PMC3157245

Abstract Article PDF–934K

Select item 5972212.

Mammalian Dynamin-like Protein DLP1 Tubulates Membranes

Yisang Yoon, Kelly R. Pitts, Mark A. McNiven

Mol Biol Cell. 2001 Sep; 12(9): 2894–2905. doi: 10.1091/mbc.12.9.2894

PMCID:: PMC59722

Abstract Article PDF–2.5M

Select item 2576613.

The Dynamin-like Protein DLP1 Is Essential for Normal Distribution and Morphology of the Endoplasmic Reticulum and Mitochondria in Mammalian Cells

K.R. Pitts, Y. Yoon, E.W. Krueger, M.A. McNiven

Mol Biol Cell. 1999 Dec; 10(12): 4403–4417. doi: 10.1091/mbc.10.12.4403

PMCID:: PMC25766

Abstract Article PDF–2.0M

Select item 1120822614.

STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells

Han Zhang, Li Chen, Jiachen Li, Jiashu Sun, Qixu Zhao, Sheng Wang, Gang Li

Genes Genomics. 2024; 46(7): 751–762. Published online 2024 May 11. doi: 10.1007/s13258-024-01522-w

PMCID:: PMC11208226

Abstract Article PDF–8.1M

Select item 1083501015.

Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation

Mathilde Dubois, Doria Boulghobra, Gilles Rochebloine, Florian Pallot, Marc Yehya, Isabelle Bornard, Sandrine Gayrard, Florence Coste, Guillaume Walther, Gregory Meyer, Jean-Charles Gaillard, Jean Armengaud, Béatrice Alpha-Bazin, Cyril Reboul

Redox Biol. 2024 Apr; 70: 103044. Published online 2024 Jan 19. doi: 10.1016/j.redox.2024.103044

PMCID:: PMC10835010

Abstract Article PDF–8.9M

Select item 1048161816.

Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation

Jin Liu, Yuqian Chen, Huan Chen, Yan Wang, Danyang Li, Qianqian Zhang, Limin Chai, Yuanjie Qiu, Jia Zhang, Nirui Shen, Qingting Wang, Jian Wang, Manxiang Li

Respir Res. 2023; 24: 216. Published online 2023 Sep 6. doi: 10.1186/s12931-023-02526-y

PMCID:: PMC10481618

Abstract Article PDF–6.2M

Select item 957016117.

PINK1 Phosphorylates Drp1^S616 to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF

Jian Shou, Yunlong Huo

Int J Mol Sci. 2022 Oct; 23(19): 11934. Published online 2022 Oct 8. doi: 10.3390/ijms231911934

PMCID:: PMC9570161

Abstract Article PDF–7.9M

Select item 925270418.

CDK5 Mediates Proinflammatory Effects of Microglia through Activated DRP1 Phosphorylation in Rat Model of Intracerebral Hemorrhage

Mingqing He, Xiaoyan Wang, Zheng Liu, Qiyuan Cui, Ying Chen, Wenqing Geng, Jinzhou Zhu, Jiabing Shen

Dis Markers. 2022; 2022: 1919064. Published online 2022 Jun 27. doi: 10.1155/2022/1919064

PMCID:: PMC9252704

Abstract Article PDF–1.1M

Select item 816841419.

ERK/Drp1‐dependent mitochondrial fission contributes to HMGB1‐induced autophagy in pulmonary arterial hypertension

Wei Feng, Jian Wang, Xin Yan, Qianqian Zhang, Limin Chai, Qingting Wang, Wenhua Shi, Yuqian Chen, Jin Liu, Zhan Qu, Shaojun Li, Xinming Xie, Manxiang Li

Cell Prolif. 2021 Jun; 54(6): e13048. Published online 2021 May 4. doi: 10.1111/cpr.13048

PMCID:: PMC8168414

Abstract Article PDF–2.3M

Select item 696561820.

Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis

Yating Wang, Miaoqing Lu, Liping Xiong, Jinjin Fan, Yi Zhou, Huiyan Li, Xuan Peng, Zhong Zhong, Yihan Wang, Fengxian Huang, Wei Chen, Xueqing Yu, Haiping Mao

Cell Death Dis. 2020 Jan; 11(1): 29. Published online 2020 Jan 16. doi: 10.1038/s41419-019-2218-5