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Select item 112317091.

A crucial role of adenosine deaminase in regulating gluconeogenesis in mice

Zhao Ding, Wenhao Ge, Xiaogang Xu, Xiaodong Xu, Qi Sun, Xi Xu, Jianfa Zhang

J Biol Chem. 2024 Jul; 300(7): 107425. Published online 2024 May 30. doi: 10.1016/j.jbc.2024.107425

PMCID:: PMC11231709

Abstract Article PDF–1.9M

Select item 86365702.

Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy

Federico A. Moretti, Giuliana Giardino, Teresa C. H. Attenborough, Athina Soragia Gkazi, Ben K. Margetts, Giancarlo la Marca, Lynette Fairbanks, Tessa Crompton, H. Bobby Gaspar

Sci Rep. 2021; 11: 23221. Published online 2021 Dec 1. doi: 10.1038/s41598-021-02572-w

Correction in:: Sci Rep. 2021; 11: 24342.

PMCID:: PMC8636570

Abstract Article PDF–4.3M

Select item 65500503.

Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema

Scott D. Collum, Jose G. Molina, Ankit Hanmandlu, Weizhen Bi, Mesias Pedroza, Tinne C. J. Mertens, Nancy Wareing, Wang Wei, Cory Wilson, Wenchao Sun, Jayakumar Rajadas, Paul L. Bollyky, Kemly M. Philip, Dewei Ren, Rajarajan A. Thandavarayan, Brian A. Bruckner, Yang Xia, Michael R. Blackburn, Harry Karmouty-Quintana

Dis Model Mech. 2019 May 1; 12(5): dmm038711. Published online 2019 May 15. doi: 10.1242/dmm.038711

PMCID:: PMC6550050

Abstract Article

Select item 64248614.

Early Enzyme Replacement Therapy Improves Hearing and Immune Defects in Adenosine Deaminase Deficient-Mice

Xiaobai Xu, Jaina Negandhi, Weixian Min, Michael Tsui, Martin Post, Robert V. Harrison, Eyal Grunebaum

Front Immunol. 2019; 10: 416. Published online 2019 Mar 13. doi: 10.3389/fimmu.2019.00416

PMCID:: PMC6424861

Abstract Article PDF–1.8M

Select item 59168295.

Adenosine deaminase deficiency: a review

Aisling M. Flinn, Andrew R. Gennery

Orphanet J Rare Dis. 2018; 13: 65. Published online 2018 Apr 24. doi: 10.1186/s13023-018-0807-5

PMCID:: PMC5916829

Abstract Article PDF–563K

Select item 34888836.

Gene therapy/bone marrow transplantation in ADA-deficient mice: roles of enzyme-replacement therapy and cytoreduction

Denise A. Carbonaro, Xiangyang Jin, Xingchao Wang, Xiao-Jin Yu, Nora Rozengurt, Michael L. Kaufman, Xiaoyan Wang, David Gjertson, Yang Zhou, Michael R. Blackburn, Donald B. Kohn

Blood. 2012 Nov 1; 120(18): 3677–3687. Prepublished online 2012 Jul 25. doi: 10.1182/blood-2012-02-408591

PMCID:: PMC3488883

Abstract Article

Select item 29159707.

Over-expression of adenosine deaminase in mouse podocytes does not reverse puromycin aminonucleoside resistance

Gaëlle Brideau, Alain Doucet

BMC Nephrol. 2010; 11: 15. Published online 2010 Jul 22. doi: 10.1186/1471-2369-11-15

PMCID:: PMC2915970

Abstract Article PDF–499K

Select item 24084268.

Pharmacological Blockade of A_2A Receptors Prevents Dermal Fibrosis in a Model of Elevated Tissue Adenosine

Patricia Fernández, Sean Trzaska, Tuere Wilder, Luis Chiriboga, Michael R. Blackburn, Bruce N. Cronstein, Edwin S. L. Chan

Am J Pathol. 2008 Jun; 172(6): 1675–1682. doi: 10.2353/ajpath.2008.070952

PMCID:: PMC2408426

Abstract Article PDF–1.5M

Select item 3672299.

Molecular cloning of the murine adenosine deaminase gene from a genetically enriched source: identification and characterization of the promoter region.

D E Ingolia, M R Al-Ubaidi, C Y Yeung, H A Bigo, D Wright, R E Kellems

Mol Cell Biol. 1986 Dec; 6(12): 4458–4466. doi: 10.1128/mcb.6.12.4458

PMCID:: PMC367229

Summary Page Browse PDF–2.1M

Select item 35969010.

Localization of a bidirectional DNA replication origin in the native locus and in episomally amplified murine adenosine deaminase loci.

S M Carroll, M L DeRose, J L Kolman, G H Nonet, R E Kelly, G M Wahl

Mol Cell Biol. 1993 May; 13(5): 2971–2981. doi: 10.1128/mcb.13.5.2971

PMCID:: PMC359690

Summary Page Browse PDF–2.7M

Select item 475199811.

Elevated Placental Adenosine Signaling Contributes to the Pathogenesis of Preeclampsia

Takayuki Iriyama, Kaiqi Sun, Nicholas F. Parchim, Jessica Li, Cheng Zhao, Anren Song, Laura A. Hart, Sean C. Blackwell, Baha M. Sibai, Lee-Nien L. Chan, Teh-Sheng Chan, M. John Hicks, Michael R. Blackburn, Rodney E. Kellems, Yang Xia

Circulation. Author manuscript; available in PMC 2016 Feb 24.

Published in final edited form as: Circulation. 2015 Feb 24; 131(8): 730–741. Published online 2014 Dec 23. doi: 10.1161/CIRCULATIONAHA.114.013740

PMCID:: PMC4751998

Abstract Article PDF–562K

Select item 404611412.

Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease

Tingting Weng, Harry Karmouty-Quintana, Luis J. Garcia-Morales, Jose G. Molina, Mesias Pedroza, Raquel R. Bunge, Brian A. Bruckner, Matthias Loebe, Harish Seethamraju, Michael R. Blackburn

FASEB J. 2013 May; 27(5): 2013–2026. doi: 10.1096/fj.12-222067

PMCID:: PMC4046114

Abstract Article

Select item 363110613.

Enhanced Airway Inflammation and Remodeling in Adenosine Deaminase-Deficient Mice Lacking the A_2B Adenosine Receptor

Yang Zhou, Amir Mohsenin, Eva Morschl, Hays W. J. Young, Jose G. Molina, Wenbin Ma, Chun-Xiao Sun, Hector Martinez-Valdez, Michael R. Blackburn

J Immunol. Author manuscript; available in PMC 2013 Apr 19.

Published in final edited form as: J Immunol. 2009 Jun 15; 182(12): 8037–8046. doi: 10.4049/jimmunol.0900515

PMCID:: PMC3631106

Abstract Article PDF–3.5M

Select item 314318114.

Interleukin-6 Contributes to Inflammation and Remodeling in a Model of Adenosine Mediated Lung Injury

Mesias Pedroza, Daniel J. Schneider, Harry Karmouty-Quintana, Julie Coote, Stevan Shaw, Rebecca Corrigan, Jose G. Molina, Joseph L. Alcorn, David Galas, Richard Gelinas, Michael R. Blackburn

PLoS One. 2011; 6(7): e22667. Published online 2011 Jul 25. doi: 10.1371/journal.pone.0022667

PMCID:: PMC3143181

Abstract Article PDF–4.9M

Select item 219325615.

Metabolic Consequences of Adenosine Deaminase Deficiency in Mice Are Associated with Defects in Alveogenesis, Pulmonary Inflammation, and Airway Obstruction

Michael R. Blackburn, Jonathan B. Volmer, Janci L. Thrasher, Hongyan Zhong, Jeff R. Crosby, James J. Lee, Rodney E. Kellems

J Exp Med. 2000 Jul 17; 192(2): 159–170. doi: 10.1084/jem.192.2.159

PMCID:: PMC2193256

Abstract Article PDF–599K

Select item 117252416.

Adenosine deaminase of cultured brain cells

Eberhard G. Trams, Carl J. Lauter

Biochem J. 1975 Dec; 152(3): 681–687. doi: 10.1042/bj1520681

PMCID:: PMC1172524

Summary Page Browse PDF–1.2M

Select item 20882417.

A₁ adenosine receptors mediate hypoxia-induced ventriculomegaly

Christopher P. Turner, Meltem Seli, Laura Ment, William Stewart, Henglin Yan, Björn Johansson, Bertil B. Fredholm, Michael Blackburn, Scott A. Rivkees

Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20): 11718–11722. Published online 2003 Sep 15. doi: 10.1073/pnas.1931975100

PMCID:: PMC208824

Abstract Article PDF–586K

Select item 4202318.

Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice.

M Wakamiya, M R Blackburn, R Jurecic, M J McArthur, R S Geske, J Cartwright, Jr, K Mitani, S Vaishnav, J W Belmont, R E Kellems, et al.

Proc Natl Acad Sci U S A. 1995 Apr 25; 92(9): 3673–3677. doi: 10.1073/pnas.92.9.3673

PMCID:: PMC42023

Summary Page Browse PDF–1.9M

Select item 545955119.

Adenosine A2B Receptor and Hyaluronan Modulate Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease

Harry Karmouty-Quintana, Tingting Weng, Luis J. Garcia-Morales, Ning-Yuan Chen, Mesias Pedroza, Hongyan Zhong, Jose G. Molina, Raquel Bunge, Brian A. Bruckner, Yang Xia, Richard A. Johnston, Matthias Loebe, Dewan Zeng, Harish Seethamraju, Luiz Belardinelli, Michael R. Blackburn

Am J Respir Cell Mol Biol. 2013 Dec; 49(6): 1038–1047. doi: 10.1165/rcmb.2013-0089OC