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Items: 1 to 20 of 354

1.
Increased peritoneal B1-like cells during acute phase of human septic peritonitis
Christian von Loeffelholz, René Winkler, Cynthia Weigel, Eva-Maria Piskor, Wolfgang Vivas, Falk Rauchfuß, Utz Settmacher, Ignacio Rubio, Sebastian Weis, Markus H. Gräler, Michael Bauer, Christian Kosan
iScience. 2024 Jul 19; 27(7): 110133. Published online 2024 Jun 6. doi: 10.1016/j.isci.2024.110133
PMCID:
PMC11231613
AbstractArticlePDF–3.6M
2.
Activation-induced deaminase expression defines mature B cell lymphoma in the mouse
Carmen Gómez-Escolar, Ester Marina-Zárate, Almudena R. Ramiro
Front Immunol. 2023; 14: 1268930. Published online 2023 Sep 21. doi: 10.3389/fimmu.2023.1268930
PMCID:
PMC10558245
AbstractArticlePDF–2.2M
3.
Selective Recognition of Carbohydrate Antigens by Germline Antibodies Isolated from AID Knockout Mice
Andrew T. DeLaitsch, Jacey R. Pridgen, Avery Tytla, Megan L. Peach, Rayleen Hu, David W. Farnsworth, Aislinn K. McMillan, Natalie Flanagan, J. Sebastian Temme, Marc C. Nicklaus, Jeffrey C. Gildersleeve
J Am Chem Soc. Author manuscript; available in PMC 2023 Sep 18.
Published in final edited form as: J Am Chem Soc. 2022 Mar 23; 144(11): 4925–4941. Published online 2022 Mar 12. doi: 10.1021/jacs.1c12745
PMCID:
PMC10506689
AbstractArticlePDF–2.3M
4.
B cell-specific knockout of AID protects against atherosclerosis
Talin Ebrahimian, France Dierick, Vincent Ta, Maria Kotsiopriftis, Jonathan O’Connor Miranda, Koren K. Mann, Alexandre Orthwein, Stephanie Lehoux
Sci Rep. 2023; 13: 8723. Published online 2023 May 30. doi: 10.1038/s41598-023-35980-1
PMCID:
PMC10229602
AbstractArticlePDF–1.4M
5.
Activation-induced cytidine deaminase expression by thymic B cells promotes T-cell tolerance and limits autoimmunity
Félix Lombard-Vadnais, Geneviève Chabot-Roy, Astrid Zahn, Sahily Rodriguez Torres, Javier M. Di Noia, Heather J. Melichar, Sylvie Lesage
iScience. 2023 Jan 20; 26(1): 105852. Published online 2022 Dec 21. doi: 10.1016/j.isci.2022.105852
PMCID:
PMC9840937
AbstractArticlePDF–4.1M
6.
IgM-associated gut bacteria in obesity and type 2 diabetes in C57BL/6 mice and humans
James A. Pearson, Heyuan Ding, Changyun Hu, Jian Peng, Brittany Galuppo, F. Susan Wong, Sonia Caprio, Nicola Santoro, Li Wen
Diabetologia. 2022; 65(8): 1398–1411. Published online 2022 May 19. doi: 10.1007/s00125-022-05711-8
PMCID:
PMC9283171
AbstractArticlePDF–1.3M
7.
A hyper-IgM syndrome mutation in activation-induced cytidine deaminase disrupts G-quadruplex binding and genome-wide chromatin localization
William T. Yewdell, Youngjun Kim, Priyanka Chowdhury, Colleen M. Lau, Ryan M. Smolkin, Kalina T. Belcheva, Keith C. Fernandez, Montserrat Cols, Wei-Feng Yen, Bharat Vaidyanathan, Davide Angeletti, Adrian B. McDermott, Jonathan W. Yewdell, Joseph C. Sun, Jayanta Chaudhuri
Immunity. Author manuscript; available in PMC 2021 Nov 17.
Published in final edited form as: Immunity. 2020 Nov 17; 53(5): 952–970.e11. Published online 2020 Oct 23. doi: 10.1016/j.immuni.2020.10.003
PMCID:
PMC8356774
AbstractArticlePDF–3.3M
8.
Abrogated AID function prolongs survival and diminishes renal pathology in the BXSB mouse model of SLE
Jing Zhu, Alayna N Hay, Ashley A Potter, Madison W Richwine, Thomas Sproule, Tanya LeRoith, John Wilson, Muneer G Hasham, Derry C Roopenian, Caroline M Leeth
J Immunol. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: J Immunol. 2020 Mar 1; 204(5): 1091–1100. Published online 2020 Jan 27. doi: 10.4049/jimmunol.1900501
PMCID:
PMC7033011
AbstractArticlePDF–2.3M
9.
Siponimod therapy implicates Th17 cells in a preclinical model of subpial cortical injury
Lesley A. Ward, Dennis S.W. Lee, Anshu Sharma, Angela Wang, Ikbel Naouar, Xianjie I. Ma, Natalia Pikor, Barbara Nuesslein-Hildesheim, Valeria Ramaglia, Jennifer L. Gommerman
JCI Insight. 2020 Jan 16; 5(1): e132522. Published online 2020 Jan 16. doi: 10.1172/jci.insight.132522
PMCID:
PMC7030818
AbstractArticlePDF–65M
10.
Fundamental Roles of Chromatin Loop Extrusion in Antibody Class Switching
Xuefei Zhang, Yu Zhang, Zhaoqing Ba, Nia Kyritsis, Rafael Casellas, Frederick W. Alt
Nature. Author manuscript; available in PMC 2020 Apr 30.
Published in final edited form as: Nature. 2019 Nov; 575(7782): 385–389. Published online 2019 Oct 30. doi: 10.1038/s41586-019-1723-0
PMCID:
PMC6856444
AbstractArticlePDF–5.6M
11.
Activation‐Induced Cytidine Deaminase Regulates Fibroblast Growth Factor/Extracellular Signal‐Regulated Kinases Signaling to Achieve the Naïve Pluripotent State During Reprogramming
Ritu Kumar, Todd Evans
Stem Cells. 2019 Aug; 37(8): 1003–1017. Published online 2019 May 8. doi: 10.1002/stem.3023
PMCID:
PMC6766926
AbstractArticlePDF–4.4M
12.
A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus
Gurvani B. Singh, Hyewon Byun, Almas F. Ali, Frank Medina, Dennis Wylie, Haridha Shivram, Andrea K. Nash, Mary M. Lozano, Jaquelin P. Dudley
mBio. 2019 Jul-Aug; 10(4): e01678-19. Published online 2019 Aug 13. doi: 10.1128/mBio.01678-19
PMCID:
PMC6692512
AbstractArticlePDF–2.5M
13.
A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets
Ángel F. Álvarez-Prado, Pablo Pérez-Durán, Arantxa Pérez-García, Alberto Benguria, Carlos Torroja, Virginia G. de Yébenes, Almudena R. Ramiro
J Exp Med. 2018 Mar 5; 215(3): 761–771. doi: 10.1084/jem.20171738
PMCID:
PMC5839764
AbstractArticlePDF–1.6M
14.
Activation-induced cytidine deaminase deficiency accelerates autoimmune diabetes in NOD mice
Qiyuan Tan, Ningwen Tai, Yangyang Li, James Pearson, Sean Pennetti, Zhiguang Zhou, F. Susan Wong, Li Wen
JCI Insight. 2018 Jan 11; 3(1): e95882. Published online 2018 Jan 11. doi: 10.1172/jci.insight.95882
PMCID:
PMC5821212
AbstractArticlePDF–3.1M
15.
Genetic and small molecule disruption of the AID/RAD51 axis similarly protect NOD mice from type 1 diabetes through expansion of regulatory B-lymphocytes
Jeremy J Ratiu, Jeremy J Racine, Muneer G Hasham, Qiming Wang, Jane A Branca, Harold D Chapman, Jing Zhu, Nina Donghia, Vivek Philip, William H Schott, Clive Wasserfall, Mark A Atkinson, Kevin D Mills, Caroline M Leeth, David V Serreze
J Immunol. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: J Immunol. 2017 Jun 1; 198(11): 4255–4267. Published online 2017 May 1. doi: 10.4049/jimmunol.1700024
PMCID:
PMC5474749
AbstractArticlePDF–2.6M
16.
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
Samiran Mondal, Nasim A. Begum, Wenjun Hu, Tasuku Honjo
Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11): E1545–E1554. Published online 2016 Feb 29. doi: 10.1073/pnas.1601678113
PMCID:
PMC4801308
AbstractArticlePDF–2.0M
17.
Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes
Leng-Siew Yeap, Joyce K. Hwang, Zhou Du, Robin M. Meyers, Fei-Long Meng, Agnė Jakubauskaitė, Mengyuan Liu, Vinidhra Mani, Donna Neuberg, Thomas B. Kepler, Jing H. Wang, Frederick W. Alt
Cell. Author manuscript; available in PMC 2016 Nov 19.
Published in final edited form as: Cell. 2015 Nov 19; 163(5): 1124–1137. Published online 2015 Nov 12. doi: 10.1016/j.cell.2015.10.042
PMCID:
PMC4751889
AbstractArticlePDF–3.3M
18.
Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells
Lyne Khair, Richard E. Baker, Erin K. Linehan, Carol E. Schrader, Janet Stavnezer
PLoS Genet. 2015 Aug; 11(8): e1005438. Published online 2015 Aug 11. doi: 10.1371/journal.pgen.1005438
PMCID:
PMC4532491
AbstractArticlePDF–2.5M
19.
Predominant role for activation-induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE
Thiago Detanico, Wenzhong Guo, Lawrence J. Wysocki
J Autoimmun. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: J Autoimmun. 2015 Apr; 58: 67–77. Published online 2015 Jan 26. doi: 10.1016/j.jaut.2015.01.006
Correction in:
volume 60 on page 86
PMCID:
PMC4492439
AbstractArticlePDF–2.4M
20.
Splice Variants of Activation Induced Deaminase (AID) Do Not Affect the Efficiency of Class Switch Recombination in Murine CH12F3 Cells
Cesare Sala, Giorgio Mattiuz, Silvia Pietrobono, Andrea Chicca, Silvestro G. Conticello
PLoS One. 2015; 10(3): e0121719. Published online 2015 Mar 24. doi: 10.1371/journal.pone.0121719
PMCID:
PMC4372541
AbstractArticlePDF–1.0M

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