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Items: 1 to 20 of 201

1.
Identification and Targeting of an Interaction between a Tyrosine Motif within Hepatitis C Virus Core Protein and AP2M1 Essential for Viral Assembly
Gregory Neveu, Rina Barouch-Bentov, Amotz Ziv-Av, Doron Gerber, Yves Jacob, Shirit Einav
PLoS Pathog. 2012 Aug; 8(8): e1002845. Published online 2012 Aug 16. doi: 10.1371/journal.ppat.1002845
PMCID:
PMC3420927
AbstractArticlePDF–1.6M
2.
Roles of AP-2 in Clathrin-Mediated Endocytosis
Emmanuel Boucrot, Saveez Saffarian, Rongying Zhang, Tomas Kirchhausen
PLoS One. 2010; 5(5): e10597. Published online 2010 May 12. doi: 10.1371/journal.pone.0010597
PMCID:
PMC2868873
AbstractArticlePDF–2.7M
3.
Internalization of Large Double-Membrane Intercellular Vesicles by a Clathrin-dependent Endocytic Process
Michelle Piehl, Corinna Lehmann, Anna Gumpert, Jean-Pierre Denizot, Dominique Segretain, Matthias M. Falk
Mol Biol Cell. 2007 Feb; 18(2): 337–347. doi: 10.1091/mbc.E06-06-0487
PMCID:
PMC1783799
AbstractArticlePDF–1.8M
4.
Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments
Peter J. McCormick, José A. Martina, Juan S. Bonifacino
Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7910–7915. Published online 2005 May 23. doi: 10.1073/pnas.0502206102
PMCID:
PMC1138261
AbstractArticlePDF–590K
5.
The 50 kDa protein subunit of assembly polypeptide (AP) AP-2 adaptor from clathrin-coated vesicles is phosphorylated on threonine-156 by AP-1 and a soluble AP50 kinase which co-purifies with the assembly polypeptides.
A Pauloin, C Thurieau
Biochem J. 1993 Dec 1; 296(Pt 2): 409–415. doi: 10.1042/bj2960409
PMCID:
PMC1137711
SummaryPage BrowsePDF–1.8M
6.
Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits.
M P Chang, W G Mallet, K E Mostov, F M Brodsky
EMBO J. 1993 May; 12(5): 2169–2180. doi: 10.1002/j.1460-2075.1993.tb05865.x
PMCID:
PMC413438
SummaryPage BrowsePDF–2.9M
7.
Endocytic Clathrin-coated Pit Formation Is Independent of Receptor Internalization Signal Levels
Francesca Santini, Michael S. Marks, James H. Keen
Mol Biol Cell. 1998 May; 9(5): 1177–1194. doi: 10.1091/mbc.9.5.1177
PMCID:
PMC25339
AbstractArticlePDF–700K
8.
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability
Ashwinkumar Subramenium Ganapathy, Kushal Saha, Eric Suchanec, Vikash Singh, Aayush Verma, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas Ma, Prashant Nighot
Autophagy. 2022; 18(9): 2086–2103. Published online 2021 Dec 29. doi: 10.1080/15548627.2021.2016233
PMCID:
PMC9466623
AbstractArticlePDF–4.7M
9.
Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target
Shuofeng Yuan, Hin Chu, Jingjing Huang, Xiaoyu Zhao, Zi-Wei Ye, Pok-Man Lai, Lei Wen, Jian-Piao Cai, Yufei Mo, Jianli Cao, Ronghui Liang, Vincent Kwok-Man Poon, Kong-Hung Sze, Jie Zhou, Kelvin Kai-Wang To, Zhiwei Chen, Honglin Chen, Dong-Yan Jin, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Sci Adv. 2020 Aug; 6(35): eaba7910. Published online 2020 Aug 28. doi: 10.1126/sciadv.aba7910
PMCID:
PMC7455044
AbstractArticlePDF–4.9M
10.
A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy
Ingo Helbig, Tania Lopez-Hernandez, Oded Shor, Peter Galer, Shiva Ganesan, Manuela Pendziwiat, Annika Rademacher, Colin A. Ellis, Nadja Hümpfer, Niklas Schwarz, Simone Seiffert, Joseph Peeden, Joseph Shen, Katalin Štěrbová, Trine Bjørg Hammer, Rikke S. Møller, Deepali N. Shinde, Sha Tang, Lacey Smith, Annapurna Poduri, Roland Krause, Felix Benninger, Katherine L. Helbig, Volker Haucke, Yvonne G. Weber, the EuroEPINOMICS-RES Consortium, the GRIN Consortium
Am J Hum Genet. 2019 Jun 6; 104(6): 1060–1072. Published online 2019 May 16. doi: 10.1016/j.ajhg.2019.04.001
PMCID:
PMC6556875
AbstractArticlePDF–2.2M
11.
Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2
Zuzana Kadlecova, Stephanie J. Spielman, Dinah Loerke, Aparna Mohanakrishnan, Dana Kim Reed, Sandra L. Schmid
J Cell Biol. 2017 Jan 2; 216(1): 167–179. doi: 10.1083/jcb.201608071
PMCID:
PMC5223608
AbstractArticlePDF–2.6M
12.
Advances in Analysis of Low Signal-to-Noise Images Link Dynamin and AP2 to the Functions of an Endocytic Checkpoint
FranÇois Aguet, Costin N. Antonescu, Marcel Mettlen, Sandra L. Schmid, Gaudenz Danuser
Dev Cell. Author manuscript; available in PMC 2014 Mar 3.
Published in final edited form as: Dev Cell. 2013 Aug 12; 26(3): 279–291. Published online 2013 Jul 25. doi: 10.1016/j.devcel.2013.06.019
PMCID:
PMC3939604
AbstractArticlePDF–7.3M
13.
BMCC1 Is an AP-2 Associated Endosomal Protein in Prostate Cancer Cells
Janelle L. Harris, Renée S. Richards, Clement W. K. Chow, Soon Lee, Misook Kim, Marion Buck, Linda Teng, Raymond Clarke, Robert A. Gardiner, Martin F. Lavin
PLoS One. 2013; 8(9): e73880. Published online 2013 Sep 6. doi: 10.1371/journal.pone.0073880
PMCID:
PMC3765211
AbstractArticlePDF–2.6M
14.
Phosphorylation of Adaptor Protein–2 μ2 Is Essential for Na+,K+-ATPase Endocytosis in Response to Either G Protein–Coupled Receptor or Reactive Oxygen Species
Zongpei Chen, Rafael T. Krmar, Laura Dada, Riad Efendiev, Ingo B. Leibiger, Carlos H. Pedemonte, Adrian I. Katz, Jacob I. Sznajder, Alejandro M. Bertorello
Am J Respir Cell Mol Biol. 2006 Jul; 35(1): 127–132. Published online 2006 Feb 23. doi: 10.1165/rcmb.2006-0044OC
PMCID:
PMC2658693
AbstractArticlePDF–215K
15.
Clathrin-mediated endocytosis in AP-2–depleted cells
Alison Motley, Nicholas A. Bright, Matthew N.J. Seaman, Margaret S. Robinson
J Cell Biol. 2003 Sep 1; 162(5): 909–918. doi: 10.1083/jcb.200305145
PMCID:
PMC2172830
AbstractArticlePDF–568K
16.
Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2μ–cargo complexes
Michael Krauss, Viktoria Kukhtina, Arndt Pechstein, Volker Haucke
Proc Natl Acad Sci U S A. 2006 Aug 8; 103(32): 11934–11939. Published online 2006 Jul 31. doi: 10.1073/pnas.0510306103
PMCID:
PMC1567676
AbstractArticlePDF–1.5M
17.
Recruitment of the Adaptor Protein 2 Complex by the Human Immunodeficiency Virus Type 2 Envelope Protein Is Necessary for High Levels of Virus Release
Beth Noble, Paolo Abada, Juan Nunez-Iglesias, Paula M. Cannon
J Virol. 2006 Mar; 80(6): 2924–2932. doi: 10.1128/JVI.80.6.2924-2932.2006
PMCID:
PMC1395462
AbstractArticlePDF–336K
18.
Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes.
I Rapoport, M Miyazaki, W Boll, B Duckworth, L C Cantley, S Shoelson, T Kirchhausen
EMBO J. 1997 May 1; 16(9): 2240–2250. doi: 10.1093/emboj/16.9.2240
PMCID:
PMC1169826
SummaryPDF–369K
19.
Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes.
W Boll, H Ohno, Z Songyang, I Rapoport, L C Cantley, J S Bonifacino, T Kirchhausen
EMBO J. 1996 Nov 1; 15(21): 5789–5795.
PMCID:
PMC452326
SummaryPage BrowsePDF–1.3M
20.
Rifampicin induces clathrin-dependent endocytosis and ubiquitin–proteasome degradation of MRP2 via oxidative stress-activated PKC-ERK/JNK/p38 and PI3K signaling pathways in HepG2 cells
Bao-yan Xu, Xu-dong Tang, Jing Chen, Hong-bo Wu, Wen-sheng Chen, Lei Chen
Acta Pharmacol Sin. 2020 Jan; 41(1): 56–64. Published online 2019 Jul 17. doi: 10.1038/s41401-019-0266-0
PMCID:
PMC7468545
AbstractArticlePDF–3.2M

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