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Select item 107915431.

RHOA^L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling

Antje Schaefer, Richard G. Hodge, Haisheng Zhang, G. Aaron Hobbs, Julien Dilly, Minh Huynh, Craig M. Goodwin, Feifei Zhang, J. Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U. Rashid, Emanuel F. Petricoin, Adrienne D. Cox, William C. Hahn, Andrew J. Aguirre, Adam J. Bass, Channing J. Der

Sci Signal. Author manuscript; available in PMC 2024 Jan 16.

Published in final edited form as: Sci Signal. 2023 Dec 19; 16(816): eadg5289. Published online 2023 Dec 19. doi: 10.1126/scisignal.adg5289

PMCID:: PMC10791543

Abstract Article PDF–2.3M

Select item 106670592.

RhoA Promotes Synovial Proliferation and Bone Erosion in Rheumatoid Arthritis through Wnt/PCP Pathway

Ning Chen, Chao-Yue Diao, Xin Huang, Wei-Xing Tan, Ya-Bing Chen, Xin-Yu Qian, Jie Gao, Dong-Bao Zhao

Mediators Inflamm. 2023; 2023: 5057009. Published online 2023 Nov 1. doi: 10.1155/2023/5057009

PMCID:: PMC10667059

Abstract Article PDF–6.3M

Select item 102515053.

RhoA G17V is sufficient to induce autoimmunity and promotes T-cell lymphomagenesis in mice

Samuel Y. Ng, Leon Brown, Kristen Stevenson, Tiffany deSouza, Jon C. Aster, Abner Louissaint, Jr, David M. Weinstock

Blood. 2018 Aug 30; 132(9): 935–947. Published online 2020 Nov 7. doi: 10.1182/blood-2017-11-818617

PMCID:: PMC10251505

Abstract Article

Select item 100776754.

RhoA promotes osteoclastogenesis and regulates bone remodeling through mTOR-NFATc1 signaling

Jirong Wang, Chengyun Xu, Jing Zhang, Yizhong Bao, Ying Tang, Xiaoling Lv, Bo Ma, Ximei Wu, Genxiang Mao

Mol Med. 2023; 29: 49. Published online 2023 Apr 5. doi: 10.1186/s10020-023-00638-1

Correction in:: Mol Med. 2023; 29: 102.

PMCID:: PMC10077675

Abstract Article PDF–3.2M

Select item 77472175.

Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation

Jun-Qi Yang, Khalid W. Kalim, Yuan Li, Yi Zheng, Fukun Guo

J Leukoc Biol. Author manuscript; available in PMC 2020 Dec 18.

Published in final edited form as: J Leukoc Biol. 2019 Nov; 106(5): 1139–1151. Published online 2019 Jul 1. doi: 10.1002/JLB.3A0119-025RRR

PMCID:: PMC7747217

Abstract Article PDF–1.2M

Select item 73874376.

Cigarette smoke induces endoplasmic reticulum stress and suppresses efferocytosis through the activation of RhoA

Hiroyuki Ito, Yoshiro Yamashita, Takeshi Tanaka, Masahiro Takaki, Minh Nhat Le, Lay-Myint Yoshida, Konosuke Morimoto

Sci Rep. 2020; 10: 12620. Published online 2020 Jul 28. doi: 10.1038/s41598-020-69610-x

Correction in:: Sci Rep. 2021; 11: 5866.

PMCID:: PMC7387437

Abstract Article PDF–3.3M

Select item 73686647.

The selective RhoA inhibitor Rhosin promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability

T. Chase Francis, Alison Gaynor, Ramesh Chandra, Megan E. Fox, Mary Kay Lobo

Biol Psychiatry. Author manuscript; available in PMC 2020 Jul 18.

Published in final edited form as: Biol Psychiatry. 2019 Jun 15; 85(12): 1001–1010. Published online 2019 Feb 13. doi: 10.1016/j.biopsych.2019.02.007

PMCID:: PMC7368664

Abstract Article PDF–1.4M

Select item 62001008.

Inhibition of RhoA reduces propofol-mediated growth cone collapse, axonal transport impairment, loss of synaptic connectivity, and behavioural deficits

M.L. Pearn, J.M. Schilling, M. Jian, J. Egawa, C. Wu, C.D. Mandyam, M.J. Fannon-Pavlich, U. Nguyen, J. Bertoglio, M. Kodama, S.K. Mahata, C. DerMardirossian, B.P. Lemkuil, R. Han, W.C. Mobley, H.H. Patel, P.M. Patel, B.P. Head

Br J Anaesth. 2018 Apr; 120(4): 745–760. Published online 2018 Feb 15. doi: 10.1016/j.bja.2017.12.033

PMCID:: PMC6200100

Abstract Article PDF–2.7M

Select item 61817569.

Withdrawal from repeated morphine administration augments expression of the RhoA network in the nucleus accumbens to control synaptic structure

Michael E. Cahill, Caleb Browne, Junshi Wang, Peter J. Hamilton, Yan Dong, Eric J. Nestler

J Neurochem. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: J Neurochem. 2018 Oct; 147(1): 84–98. Published online 2018 Sep 26. doi: 10.1111/jnc.14563

PMCID:: PMC6181756

Abstract Article PDF–1.1M

Select item 599062110.

RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

Alba Manresa-Arraut, Flemming Fryd Johansen, Cord Brakebusch, Shohreh Issazadeh-Navikas, Henrik Hasseldam

Front Immunol. 2018; 9: 1235. Published online 2018 May 31. doi: 10.3389/fimmu.2018.01235

PMCID:: PMC5990621

Abstract Article PDF–6.8M

Select item 548469411.

Discovery of long-range inhibitory signaling to ensure single axon formation

Tetsuya Takano, Mengya Wu, Shinichi Nakamuta, Honda Naoki, Naruki Ishizawa, Takashi Namba, Takashi Watanabe, Chundi Xu, Tomonari Hamaguchi, Yoshimitsu Yura, Mutsuki Amano, Klaus M. Hahn, Kozo Kaibuchi

Nat Commun. 2017; 8: 33. Published online 2017 Jun 26. doi: 10.1038/s41467-017-00044-2

PMCID:: PMC5484694

Abstract Article PDF–5.0M

Select item 547968812.

cAMP-Dependent Regulation of RhoA/Rho-kinase Attenuates Detrusor Overactivity in a Novel Mouse Experimental Model

William Akakpo, Biljana Musicki, Arthur L. Burnett

BJU Int. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: BJU Int. 2017 Jul; 120(1): 143–151. Published online 2017 Apr 11. doi: 10.1111/bju.13847

PMCID:: PMC5479688

Abstract Article PDF–675K

Select item 516740313.

RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress

Marie-Pier Girouard, Madeline Pool, Ricardo Alchini, Isabel Rambaldi, Alyson E. Fournier

PLoS One. 2016; 11(12): e0168641. Published online 2016 Dec 19. doi: 10.1371/journal.pone.0168641

PMCID:: PMC5167403

Abstract Article PDF–2.0M

Select item 497021814.

RhoA-Mediated Functions in C3H10T1/2 Osteoprogenitors Are Substrate Topography Dependent

Yoichiro Ogino, Ruiwei Liang, Daniela B. S. Mendonça, Gustavo Mendonça, Masako Nagasawa, Kiyoshi Koyano, Lyndon F. Cooper

J Cell Physiol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: J Cell Physiol. 2016 Mar; 231(3): 568–575. doi: 10.1002/jcp.25100

PMCID:: PMC4970218

Abstract Article PDF–1.0M

Select item 493620815.

RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal

Zongshun Huang, Li Zhang, Yuanhan Chen, Hong Zhang, Chunping Yu, Fangjian Zhou, Zhiling Zhang, Lijuan Jiang, Ruizhao Li, Jianchao Ma, Zhuo Li, Yuxiong Lai, Ting Lin, Xinchen Zhao, Qianmei Zhang, Bin Zhang, Zhiming Ye, Shuangxin Liu, Wenjian Wang, Xinling Liang, Ruyi Liao, Wei Shi

BMC Nephrol. 2016; 17: 66. Published online 2016 Jul 7. doi: 10.1186/s12882-016-0287-6

PMCID:: PMC4936208

Abstract Article PDF–2.3M

Select item 477134916.

Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities

Carlos Quesada-Gómez, Diana López-Ureña, Nicole Chumbler, Heather K. Kroh, Carolina Castro-Peña, César Rodríguez, Josué Orozco-Aguilar, Sara González-Camacho, Alexandra Rucavado, Caterina Guzmán-Verri, Trevor D. Lawley, D. Borden Lacy, Esteban Chaves-Olarte

Infect Immun. 2016 Mar; 84(3): 856–865. Prepublished online 2016 Jan 11. Published online 2016 Feb 24. doi: 10.1128/IAI.01291-15

PMCID:: PMC4771349

Abstract Article PDF–1.5M

Select item 470047717.

Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling

Ludovico Fusco, Riwal Lefort, Kevin Smith, Fethallah Benmansour, German Gonzalez, Caterina Barillari, Bernd Rinn, Francois Fleuret, Pascal Fua, Olivier Pertz

J Cell Biol. 2016 Jan 4; 212(1): 91–111. doi: 10.1083/jcb.201506018

PMCID:: PMC4700477

Abstract Article PDF–5.0M

Select item 441536618.

RhoA Biological Activity Is Dependent on Prenylation but Independent of Specific Isoprenoid Modification

Patricia A. Solski, Whitney Helms, Patricia J. Keely, Lishan Su, Channing J. Der

Cell Growth Differ. Author manuscript; available in PMC 2015 Apr 30.

Published in final edited form as: Cell Growth Differ. 2002 Aug; 13(8): 363–373.

PMCID:: PMC4415366

Abstract Article PDF–643K

Select item 430010919.

RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis

Jessica Lauriol, Kimberly Keith, Fabrice Jaffré, Anthony Couvillon, Abdel Saci, Sanjeewa A. Goonasekera, Jason R. McCarthy, Chase W. Kessinger, Jianxun Wang, Qingen Ke, Peter M. Kang, Jeffery D. Molkentin, Christopher Carpenter, Maria I. Kontaridis

Sci Signal. Author manuscript; available in PMC 2015 Apr 21.

Published in final edited form as: Sci Signal. 2014 Oct 21; 7(348): ra100. Published online 2014 Oct 21. doi: 10.1126/scisignal.2005262

PMCID:: PMC4300109

Abstract Article PDF–1.6M

Select item 405284720.

RhoA Controls Wnt Upregulation on Microstructured Titanium Surfaces

Simone Lumetti, Silvia Mazzotta, Sara Ferrillo, Maddalena Piergianni, Marilina Piemontese, Giovanni Passeri, Guido Maria Macaluso, Carlo Galli

Biomed Res Int. 2014; 2014: 401859. Published online 2014 May 14. doi: 10.1155/2014/401859

PMCID:: PMC4052847

Abstract Article PDF–1.9M

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