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Items: 1 to 20 of 190

1.
Valproic acid attenuates cellular senescence in diabetic kidney disease through the inhibition of complement C5a receptors
Melinda T. Coughlan, Mark Ziemann, Adrienne Laskowski, Trent M. Woodruff, Sih Min Tan
Sci Rep. 2022; 12: 20278. Published online 2022 Nov 24. doi: 10.1038/s41598-022-24851-w
PMCID:
PMC9700697
AbstractArticlePDF–5.0M
2.
Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells
Ranjit K. Sahu, Sandhya Xavier, Daniel Chauss, Luopin Wang, Claude Chew, Ronald Taylor, William B. Stallcup, Jennie Z. Ma, Majid Kazemian, Behdad Afzali, Jörg Köhl, Didier Portilla
Am J Physiol Renal Physiol. 2022 Jun 1; 322(6): F597–F610. Published online 2022 Apr 4. doi: 10.1152/ajprenal.00404.2021
PMCID:
PMC9054266
AbstractArticle
3.
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis
Hirotaka Hiyoshi, Bevin C. English, Vladimir E. Diaz-Ochoa, Tamding Wangdi, Lillian F. Zhang, Miako Sakaguchi, Takeshi Haneda, Renée M. Tsolis, Andreas J. Bäumler
Cell Host Microbe. Author manuscript; available in PMC 2023 Feb 9.
Published in final edited form as: Cell Host Microbe. 2022 Feb 9; 30(2): 163–170.e6. Published online 2021 Dec 23. doi: 10.1016/j.chom.2021.12.001
PMCID:
PMC8831471
AbstractArticlePDF–973K
4.
The role of complement C5a receptor in DPSC odontoblastic differentiation and in vivo reparative dentin formation
Muhammad Irfan, Ji-Hyun Kim, Hassan Marzban, David A. Reed, Anne George, Lyndon F. Cooper, Seung Chung
Int J Oral Sci. 2022; 14: 7. Published online 2022 Jan 27. doi: 10.1038/s41368-022-00158-4
PMCID:
PMC8795457
AbstractArticlePDF–3.4M
5.
Exogenous inter-α inhibitor proteins prevent cell death and improve ischemic stroke outcomes in mice
Louise D. McCullough, Meaghan Roy-O’Reilly, Yun-Ju Lai, Anthony Patrizz, Yan Xu, Juneyoung Lee, Aleah Holmes, Daniel C. Kraushaar, Anjali Chauhan, Lauren H. Sansing, Barbara S. Stonestreet, Liang Zhu, Julia Kofler, Yow-Pin Lim, Venugopal Reddy Venna
J Clin Invest. 2021 Sep 1; 131(17): e144898. Published online 2021 Sep 1. doi: 10.1172/JCI144898
PMCID:
PMC8409590
AbstractArticlePDF–9.8M
6.
C5aR1 is a master regulator in Colorectal Tumorigenesis via Immune modulation
Peipei Ding, Ling Li, Luying Li, Xinyue Lv, Danlei Zhou, Qingkai Wang, Jianfeng Chen, Chaoqun Yang, Enjie Xu, Weixing Dai, Xin Zhang, Na Wang, Qi Wang, Wei Zhang, Long Zhang, Yuzhen Zhou, Hongyu Gu, Qunying Lei, Xuhui Zhou, Weiguo Hu
Theranostics. 2020; 10(19): 8619–8632. Published online 2020 Jul 9. doi: 10.7150/thno.45058
PMCID:
PMC7392014
AbstractArticlePDF–3.1M
7.
C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection
Daria Briukhovetska, Birte Ohm, Fabian T. Mey, Julio Aliberti, Marie Kleingarn, Markus Huber-Lang, Christian M. Karsten, Jörg Köhl
Front Immunol. 2020; 11: 1397. Published online 2020 Jul 8. doi: 10.3389/fimmu.2020.01397
PMCID:
PMC7362728
AbstractArticlePDF–1.5M
8.
Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis
Julien Carvelli, Olivier Demaria, Frédéric Vély, Luciana Batista, Nassima Chouaki Benmansour, Joanna Fares, Sabrina Carpentier, Marie-Laure Thibult, Ariane Morel, Romain Remark, Pascale André, Agnès Represa, Christelle Piperoglou, the Explore COVID-19 IPH group, the Explore COVID-19 Marseille Immunopole group, Pierre Yves Cordier, Erwan Le Dault, Christophe Guervilly, Pierre Simeone, Marc Gainnier, Yannis Morel, Mikael Ebbo, Nicolas Schleinitz, Eric Vivier
Nature. Author manuscript; available in PMC 2021 Mar 10.
Published in final edited form as: Nature. 2020 Dec 1; 588(7836): 146–150. Published online 2020 Jul 29. doi: 10.1038/s41586-020-2600-6
PMCID:
PMC7116884
AbstractArticlePDF–2.6M
9.
C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis
Quan-you Zheng, Shen-ju Liang, Feng Xu, Gui-qing Li, Na Luo, Shun Wu, You Li, Ming Tang, Yu Zhong, Jian Chen, Di Yang, Dao-dong Sun, Ke-qin Zhang, Gui-lian Xu
Front Immunol. 2019; 10: 1866. Published online 2019 Aug 7. doi: 10.3389/fimmu.2019.01866
PMCID:
PMC6692472
AbstractArticlePDF–3.4M
10.
The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury
Faith H. Brennan, Richard Gordon, Hong W. Lao, Patrick J. Biggins, Stephen M. Taylor, Robin J.M. Franklin, Trent M. Woodruff, Marc J. Ruitenberg
J Neurosci. 2015 Apr 22; 35(16): 6517–6531. doi: 10.1523/JNEUROSCI.5218-14.2015
PMCID:
PMC6605214
AbstractArticlePDF–3.1M
11.
Complement 5a Receptor deficiency does not influence adverse cardiac remodeling after pressure-overload in mice
Judith J. de Haan, Lena Bosch, Anouska Borgman, Marissa Bastemeijer, Maike A. D. Brans, Sander M. van de Weg, Dominique P. V. de Kleijn, Joost P. G. Sluijter, Hamid el Azzouzi, Saskia C. A. de Jager
Sci Rep. 2017; 7: 17045. Published online 2017 Dec 6. doi: 10.1038/s41598-017-16957-3
PMCID:
PMC5719022
AbstractArticlePDF–1.6M
12.
Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss
Michael X. Hernandez, Shan Jiang, Tracy A. Cole, Shu-Hui Chu, Maria I. Fonseca, Melody J. Fang, Lindsay A. Hohsfield, Maria D. Torres, Kim N. Green, Rick A. Wetsel, Ali Mortazavi, Andrea J. Tenner
Mol Neurodegener. 2017; 12: 66. Published online 2017 Sep 18. doi: 10.1186/s13024-017-0210-z
PMCID:
PMC5604420
AbstractArticlePDF–5.5M
13.
Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing
Stephanie Bergdolt, Anna Kovtun, Yvonne Hägele, Astrid Liedert, Thorsten Schinke, Michael Amling, Markus Huber-Lang, Anita Ignatius
PLoS One. 2017; 12(6): e0179512. Published online 2017 Jun 14. doi: 10.1371/journal.pone.0179512
PMCID:
PMC5470759
AbstractArticlePDF–18M
14.
Differential regulation of C5a receptor 1 in innate immune cells during the allergic asthma effector phase
Fanny Ender, Anna V. Wiese, Inken Schmudde, Jing Sun, Tillman Vollbrandt, Peter König, Yves Laumonnier, Jörg Köhl
PLoS One. 2017; 12(2): e0172446. Published online 2017 Feb 23. doi: 10.1371/journal.pone.0172446
PMCID:
PMC5322932
AbstractArticlePDF–5.5M
15.
The complement factor 5a receptor 1 has a pathogenic role in chronic inflammation and renal fibrosis in a murine model of chronic pyelonephritis
Naheed Choudhry, Ke Li, Ting Zhang, Kun-Yi Wu, Yun Song, Conrad A. Farrar, Na Wang, Cheng-Fei Liu, Qi Peng, Weiju Wu, Steven H. Sacks, Wuding Zhou
Kidney Int. 2016 Sep; 90(3): 540–554. doi: 10.1016/j.kint.2016.04.023
PMCID:
PMC4996631
AbstractArticle
16.
Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol-induced liver injury in mice
Rebecca L McCullough, Megan R McMullen, Dola Das, Sanjoy Roychowdhury, Michael G. Strainic, M. Edward Medof, Laura E Nagy
Mol Immunol. Author manuscript; available in PMC 2017 Jul 1.
Published in final edited form as: Mol Immunol. 2016 Jul; 75: 122–132. Published online 2016 Jun 6. doi: 10.1016/j.molimm.2016.05.006
PMCID:
PMC4939119
AbstractArticlePDF–1.5M
17.
Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist
Diane L. Sewell, Brendon Nacewicz, Frances Liu, Sinarack Macvilay, Anna Erdei, John D. Lambris, Matyas Sandor, Zsuzsa Fabry
J Neuroimmunol. Author manuscript; available in PMC 2016 Feb 25.
Published in final edited form as: J Neuroimmunol. 2004 Oct; 155(0): 55–63. doi: 10.1016/j.jneuroim.2004.06.003
PMCID:
PMC4766842
AbstractArticlePDF–927K
18.
Real-Time Imaging of Interactions of Neutrophils with Cryptococcus neoformans Demonstrates a Crucial Role of Complement C5a-C5aR Signaling
Donglei Sun, Mingshun Zhang, Gongguan Liu, Hui Wu, Xiaoping Zhu, Hong Zhou, Meiqing Shi
Infect Immun. 2016 Jan; 84(1): 216–229. Prepublished online 2015 Oct 26. Published online 2015 Dec 28. doi: 10.1128/IAI.01197-15
PMCID:
PMC4693990
AbstractArticlePDF–2.6M
19.
Role of the complement anaphylatoxin C5a-receptor pathway in atopic dermatitis in mice
LIN DANG, LEI HE, YAN WANG, JIKUI XIONG, BINGXUE BAI, YUZHEN LI
Mol Med Rep. 2015 Jun; 11(6): 4183–4189. Published online 2015 Feb 4. doi: 10.3892/mmr.2015.3301
PMCID:
PMC4394951
AbstractArticlePDF–692K
20.
Treatment with the C5a Receptor/CD88 Antagonist PMX205 Reduces Inflammation in a Murine Model of Allergic Asthma
Elizabeth B. Staab, Sam D. Sanderson, Sandra M. Wells, Jill A. Poole
Int Immunopharmacol. Author manuscript; available in PMC 2015 Aug 1.
Published in final edited form as: Int Immunopharmacol. 2014 Aug; 21(2): 293–300. Published online 2014 May 21. doi: 10.1016/j.intimp.2014.05.008
PMCID:
PMC4108528
AbstractArticlePDF–612K

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