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Select item 107620681.

Selective blockade of Ca_v1.2 (α1C) versus Ca_v1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine

Pietro Mesirca, Jean Chemin, Christian Barrère, Eleonora Torre, Laura Gallot, Arnaud Monteil, Isabelle Bidaud, Sylvie Diochot, Michel Lazdunski, Tuck Wah Soong, Stéphanie Barrère-Lemaire, Matteo E. Mangoni, Joël Nargeot

Nat Commun. 2024; 15: 54. Published online 2024 Jan 2. doi: 10.1038/s41467-023-43502-w

PMCID:: PMC10762068

Abstract Article PDF–2.2M

Select item 99449422.

Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac Ca_V1.2 calcium channel

Liam Hovey, Xiaoyun Guo, Yi Chen, Qinghang Liu, William A. Catterall

Front Physiol. 2023; 14: 1049611. Published online 2023 Feb 8. doi: 10.3389/fphys.2023.1049611

PMCID:: PMC9944942

Abstract Article PDF–1.7M

Select item 96448253.

The Ca_V1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca²⁺ channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome

Jennifer L. Sanderson, Ronald K. Freund, Anna M. Castano, Timothy A. Benke, Mark L. Dell’Acqua

Neuropharmacology. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Neuropharmacology. 2022 Dec 1; 220: 109271. Published online 2022 Sep 24. doi: 10.1016/j.neuropharm.2022.109271

PMCID:: PMC9644825

Abstract Article PDF–1.8M

Select item 91770744.

Ca_v1.3 calcium channels are full-range linear amplifiers of firing frequencies in lateral DA SN neurons

Josef Shin, Lora Kovacheva, Dominique Thomas, Strahinja Stojanovic, Christopher J. Knowlton, Johanna Mankel, Johannes Boehm, Navid Farassat, Carlos Paladini, Jörg Striessnig, Carmen C. Canavier, Gerd Geisslinger, Jochen Roeper

Sci Adv. 2022 Jun; 8(23): eabm4560. Published online 2022 Jun 8. doi: 10.1126/sciadv.abm4560

PMCID:: PMC9177074

Abstract Article PDF–2.9M

Select item 89979675.

L-Type Ca_v1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells

Julien Louradour, Olivier Bortolotti, Eleonora Torre, Isabelle Bidaud, Ned Lamb, Anne Fernandez, Jean-Yves Le Guennec, Matteo E. Mangoni, Pietro Mesirca

Cells. 2022 Apr; 11(7): 1114. Published online 2022 Mar 25. doi: 10.3390/cells11071114

PMCID:: PMC8997967

Abstract Article PDF–4.1M

Select item 87486716.

Enhanced long-term potentiation and impaired learning in mice lacking alternative exon 33 of Ca_V1.2 calcium channel

Sheeja Navakkode, Jing Zhai, Yuk Peng Wong, Guang Li, Tuck Wah Soong

Transl Psychiatry. 2022; 12: 1. Published online 2022 Jan 10. doi: 10.1038/s41398-021-01683-2

PMCID:: PMC8748671

Abstract Article PDF–1.2M

Select item 81741357.

A Critical Neurodevelopmental Role for L-Type Voltage-Gated Calcium Channels in Neurite Extension and Radial Migration

Satoshi Kamijo, Yuichiro Ishii, Shin-ichiro Horigane, Kanzo Suzuki, Masamichi Ohkura, Junichi Nakai, Hajime Fujii, Sayaka Takemoto-Kimura, Haruhiko Bito

J Neurosci. 2018 Jun 13; 38(24): 5551–5566. doi: 10.1523/JNEUROSCI.2357-17.2018

PMCID:: PMC8174135

Abstract Article PDF–25M

Select item 79803768.

Dual-process brain mitochondria isolation preserves function and clarifies protein composition

Maria F. Noterman, Kalyani Chaubey, Kristi Lin-Rahardja, Anjali M. Rajadhyaksha, Andrew A. Pieper, Eric B. Taylor

Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2019046118. Published online 2021 Mar 8. doi: 10.1073/pnas.2019046118

PMCID:: PMC7980376

Abstract Article PDF–1.2M

Select item 78963409.

β-Adrenergic control of sarcolemmal Ca_V1.2 abundance by small GTPase Rab proteins

Silvia G. del Villar, Taylor L. Voelker, Maartje Westhoff, Gopireddy R. Reddy, Heather C. Spooner, Manuel F. Navedo, Eamonn J. Dickson, Rose E. Dixon

Proc Natl Acad Sci U S A. 2021 Feb 16; 118(7): e2017937118. Published online 2021 Feb 8. doi: 10.1073/pnas.2017937118

PMCID:: PMC7896340

Abstract Article PDF–4.1M

Select item 747651310.

Cav1.2 L-type calcium channels regulate stress coping behavior via serotonin neurons

Daniel G. Ehlinger, Kathryn G. Commons

Neuropharmacology. Author manuscript; available in PMC 2020 Sep 7.

Published in final edited form as: Neuropharmacology. 2019 Jan; 144: 282–290. Published online 2018 Sep 1. doi: 10.1016/j.neuropharm.2018.08.033

PMCID:: PMC7476513

Abstract Article PDF–662K

Select item 739643011.

A mouse model of Timothy syndrome exhibits altered social competitive dominance and inhibitory neuron development

Shin‐ichiro Horigane, Yukihiro Ozawa, Jun Zhang, Hiroe Todoroki, Pan Miao, Asahi Haijima, Yuchio Yanagawa, Shuhei Ueda, Shigeo Nakamura, Masaki Kakeyama, Sayaka Takemoto‐Kimura

FEBS Open Bio. 2020 Aug; 10(8): 1436–1446. Published online 2020 Jul 19. doi: 10.1002/2211-5463.12924

PMCID:: PMC7396430

Abstract Article PDF–1.0M

Select item 717890912.

Deletion of Voltage-Gated Calcium Channels in Astrocytes during Demyelination Reduces Brain Inflammation and Promotes Myelin Regeneration in Mice

Norma N. Zamora, Veronica T. Cheli, Diara A. Santiago González, Rensheng Wan, Pablo M. Paez

J Neurosci. 2020 Apr 22; 40(17): 3332–3347. doi: 10.1523/JNEUROSCI.1644-19.2020

PMCID:: PMC7178909

Abstract Article PDF–14M

Select item 669712313.

Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome

Veronica T. Cheli, Diara A. Santiago González, Norma N. Zamora, Tenzing N. Lama, Vilma Spreuer, Randall L. Rasmusson, Glenna C. Bett, Georgia Panagiotakos, Pablo M. Paez

Glia. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Glia. 2018 Nov; 66(11): 2324–2339. Published online 2018 Aug 26. doi: 10.1002/glia.23468

PMCID:: PMC6697123

Abstract Article PDF–3.2M

Select item 663464314.

Homeostatic Switch in Hebbian Plasticity and Fear Learning after Sustained Loss of Ca_v1.2 Calcium Channels

Nicole Langwieser, Carl J. Christel, Thomas Kleppisch, Franz Hofmann, Carsten T. Wotjak, Sven Moosmang

J Neurosci. 2010 Jun 23; 30(25): 8367–8375. doi: 10.1523/JNEUROSCI.4164-08.2010

PMCID:: PMC6634643

Abstract Article PDF–1.2M

Select item 659148115.

Blockade of microglial Cav1.2 Ca²⁺ channel exacerbates the symptoms in a Parkinson’s disease model

Xinshuang Wang, Hironao Saegusa, Soontaraporn Huntula, Tsutomu Tanabe

Sci Rep. 2019; 9: 9138. Published online 2019 Jun 24. doi: 10.1038/s41598-019-45681-3

PMCID:: PMC6591481

Abstract Article PDF–4.4M

Select item 658524516.

Alterations of Calcium Channels in a Mouse Model of Huntington’s Disease and Neuroprotection by Blockage of Ca_V1 Channels

Artur S. Miranda, Pablo Leal Cardozo, Flavia R. Silva, Jessica M. de Souza, Isabella G. Olmo, Jader S. Cruz, Marcus Vinícius Gomez, Fabiola M. Ribeiro, Luciene B. Vieira

ASN Neuro. 2019 Jan-Dec; 11: 1759091419856811. Published online 2019 Jun 19. doi: 10.1177/1759091419856811

PMCID:: PMC6585245

Abstract Article PDF–1.1M

Select item 646246417.

β‐adrenergic‐mediated dynamic augmentation of sarcolemmal Ca_V1.2 clustering and co‐operativity in ventricular myocytes

Danica W. Ito, Karen I. Hannigan, Debapriya Ghosh, Bing Xu, Silvia G. del Villar, Yang K. Xiang, Eamonn J. Dickson, Manuel F. Navedo, Rose E. Dixon

J Physiol. 2019 Apr 15; 597(8): 2139–2162. Published online 2019 Mar 12. doi: 10.1113/JP277283

PMCID:: PMC6462464

Abstract Article PDF–3.1M

Select item 641877918.

Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2‐neo mouse rescued by L‐type calcium channel blockers

Chiara Calorio, Daniela Gavello, Laura Guarina, Chiara Salio, Marco Sassoè‐Pognetto, Chiara Riganti, Federico Tommaso Bianchi, Nadja T. Hofer, Petronel Tuluc, Gerald J. Obermair, Paola Defilippi, Fiorella Balzac, Emilia Turco, Glenna C. Bett, Randall L. Rasmusson, Emilio Carbone

J Physiol. 2019 Mar 15; 597(6): 1705–1733. Published online 2019 Jan 28. doi: 10.1113/JP277487

PMCID:: PMC6418779

Abstract Article PDF–5.3M

Select item 639700119.

A G_s-coupled purinergic receptor boosts Ca²⁺ influx and vascular contractility during diabetic hyperglycemia

Maria Paz Prada, Arsalan U Syed, Olivia R Buonarati, Gopireddy R Reddy, Matthew A Nystoriak, Debapriya Ghosh, Sergi Simó, Daisuke Sato, Kent C Sasse, Sean M Ward, Luis F Santana, Yang K Xiang, Johannes W Hell, Madeline Nieves-Cintrón, Manuel F Navedo

eLife. 2019; 8: e42214. Published online 2019 Mar 1. doi: 10.7554/eLife.42214

PMCID:: PMC6397001

Abstract Article PDF–6.5M

Select item 599548220.

D-cis-Diltiazem Can Produce Oxidative Stress in Healthy Depolarized Rods In Vivo

Bruce A. Berkowitz, Robert H. Podolsky, Benjamin Farrell, Hojun Lee, Christopher Trepanier, Ali M. Berri, Kristin Dernay, Emma Graffice, Fatema Shafie-Khorassani, Timothy S. Kern, Robin Roberts

Invest Ophthalmol Vis Sci. 2018 Jun; 59(7): 2999–3010. doi: 10.1167/iovs.18-23829