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Select item 55595841.

Re-characterization of the Glomerulopathy in CD2AP Deficient Mice by High-Resolution Helium Ion Scanning Microscopy

Kenji Tsuji, Teodor G. Păunescu, Hani Suleiman, Dongping Xie, Fahmy A. Mamuya, Jeffrey H. Miner, Hua A. Jenny Lu

Sci Rep. 2017; 7: 8321. Published online 2017 Aug 16. doi: 10.1038/s41598-017-08304-3

PMCID:: PMC5559584

Abstract Article PDF–3.7M

Select item 52102062.

Podocyte injury: the role of proteinuria, urinary plasminogen, and oxidative stress

Leopoldo Raij, Runxia Tian, Jenny S. Wong, John C. He, Kirk N. Campbell

Am J Physiol Renal Physiol. 2016 Dec 1; 311(6): F1308–F1317. Published online 2016 Jun 22. doi: 10.1152/ajprenal.00162.2016

PMCID:: PMC5210206

Abstract Article

Select item 46343733.

The Alzheimer's disease risk factor CD2AP maintains blood–brain barrier integrity

J. Nicholas Cochran, Travis Rush, Susan C. Buckingham, Erik D. Roberson

Hum Mol Genet. 2015 Dec 1; 24(23): 6667–6674. Published online 2015 Sep 10. doi: 10.1093/hmg/ddv371

PMCID:: PMC4634373

Abstract Article PDF–629K

Select item 44309194.

Pathogenic pathways are activated in each major cell type of the glomerulus in the Cd2ap mutant mouse model of focal segmental glomerulosclerosis

Eric W. Brunskill, S. Steven Potter

BMC Nephrol. 2015; 16: 71. Published online 2015 May 13. doi: 10.1186/s12882-015-0063-z

PMCID:: PMC4430919

Abstract Article PDF–1.9M

Select item 38585355.

CD2-associated protein regulates plasmacytoid dendritic cell migration, but is dispensable for their development and cytokine production

Subhashini Srivatsan, Melissa Swiecki, Karel Otero, Marina Cella, Andrey S. Shaw

J Immunol. Author manuscript; available in PMC 2014 Jun 15.

Published in final edited form as: J Immunol. 2013 Dec 15; 191(12): 10.4049/jimmunol.1300454. Published online 2013 Nov 11. doi: 10.4049/jimmunol.1300454

PMCID:: PMC3858535

Abstract Article PDF–1.9M

Select item 67133506.

A bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells

Andrew S. Potter, Keri Drake, Eric W. Brunskill, S. Steven Potter

PLoS One. 2019; 14(8): e0216261. Published online 2019 Aug 28. doi: 10.1371/journal.pone.0216261

PMCID:: PMC6713350

Abstract Article PDF–2.5M

Select item 56014337.

Ultrastructural Characterization of the Glomerulopathy in Alport Mice by Helium Ion Scanning Microscopy (HIM)

Kenji Tsuji, Hani Suleiman, Jeffrey H. Miner, James M. Daley, Diane E. Capen, Teodor G. Păunescu, Hua A. Jenny Lu

Sci Rep. 2017; 7: 11696. Published online 2017 Sep 15. doi: 10.1038/s41598-017-12064-5

PMCID:: PMC5601433

Abstract Article PDF–3.4M

Select item 55875938.

Inhibition of SHIP2 in CD2AP-deficient podocytes ameliorates reactive oxygen species generation but aggravates apoptosis

Pauliina Saurus, Tuomas A. Tolvanen, Sonja Lindfors, Sara Kuusela, Harry Holthöfer, Eero Lehtonen, Sanna Lehtonen

Sci Rep. 2017; 7: 10731. Published online 2017 Sep 6. doi: 10.1038/s41598-017-10512-w

PMCID:: PMC5587593

Abstract Article PDF–3.4M

Select item 52100859.

Bin1 and CD2AP polarise the endocytic generation of beta‐amyloid

Florent Ubelmann, Tatiana Burrinha, Laura Salavessa, Ricardo Gomes, Cláudio Ferreira, Nuno Moreno, Cláudia Guimas Almeida

EMBO Rep. 2017 Jan; 18(1): 102–122. Published online 2016 Nov 28. doi: 10.15252/embr.201642738

PMCID:: PMC5210085

Abstract Article PDF–4.1M

Select item 453013210.

Dendrin Ablation Prolongs Life Span by Delaying Kidney Failure

Astrid Weins, Jenny S. Wong, John M. Basgen, Ritu Gupta, Ilse Daehn, Lisette Casagrande, David Lessman, Monica Schwartzman, Kristin Meliambro, Jaakko Patrakka, Andrey Shaw, Karl Tryggvason, John Cijiang He, Susanne B. Nicholas, Peter Mundel, Kirk N. Campbell

Am J Pathol. 2015 Aug; 185(8): 2143–2157. doi: 10.1016/j.ajpath.2015.04.011

PMCID:: PMC4530132

Abstract Article PDF–3.7M

Select item 437440611.

Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model

Fan Liao, Hong Jiang, Subhashini Srivatsan, Qingli Xiao, Katheryn B Lefton, Kaoru Yamada, Thomas E Mahan, Jin-Moo Lee, Andrey S Shaw, David M Holtzman

Mol Neurodegener. 2015; 10: 12. Published online 2015 Mar 19. doi: 10.1186/s13024-015-0006-y

PMCID:: PMC4374406

Abstract Article PDF–1.9M

Select item 404210212.

Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro

Gabriela Casalena, Stefanie Krick, Ilse Daehn, Liping Yu, Wenjun Ju, Shaolin Shi, Su-yi Tsai, Vivette D'Agati, Maja Lindenmeyer, Clemens D. Cohen, Detlef Schlondorff, Erwin P. Bottinger

Am J Physiol Renal Physiol. 2014 Jun 1; 306(11): F1372–F1380. Published online 2014 Mar 5. doi: 10.1152/ajprenal.00608.2013

PMCID:: PMC4042102

Abstract Article

Select item 353630013.

CD2AP Links Cortactin and Capping Protein at the Cell Periphery To Facilitate Formation of Lamellipodia

Jianping Zhao, Serawit Bruck, Saso Cemerski, Lei Zhang, Boyd Butler, Adish Dani, John A. Cooper, Andrey S. Shaw

Mol Cell Biol. 2013 Jan; 33(1): 38–47. doi: 10.1128/MCB.00734-12

PMCID:: PMC3536300

Abstract Article PDF–1.6M

Select item 263482914.

The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage

Andrew J. Bredemeyer, Jessica H. Geahlen, Victoria G. Weis, Won Jae Huh, Bernd H. Zinselmeyer, Subhashini Srivatsan, Mark J. Miller, Andrey S. Shaw, Jason C. Mills

Dev Biol. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: Dev Biol. 2009 Jan 1; 325(1): 211–224. Published online 2008 Oct 31. doi: 10.1016/j.ydbio.2008.10.025

PMCID:: PMC2634829

Abstract Article PDF–3.4M

Select item 185060715.

CD2AP Localizes to the Slit Diaphragm and Binds to Nephrin via a Novel C-Terminal Domain

Neng-Yao Shih, Jun Li, Ramzi Cotran, Peter Mundel, Jeffrey H. Miner, Andrey S. Shaw

Am J Pathol. 2001 Dec; 159(6): 2303–2308. doi: 10.1016/S0002-9440(10)63080-5

PMCID:: PMC1850607

Abstract Article PDF–259K

Select item 531470116.

CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes

Beina Teng, Patricia Schroder, Janina Müller-Deile, Heiko Schenk, Lynne Staggs, Irini Tossidou, Ivan Dikic, Hermann Haller, Mario Schiffer

Diabetes. 2016 Dec; 65(12): 3667–3679. Published online 2016 Aug 16. doi: 10.2337/db16-0081

PMCID:: PMC5314701

Abstract Article PDF–2.5M

Select item 482965017.

The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity

Benjamin J. Harrison, Gayathri Venkat, James L. Lamb, Tom H. Hutson, Cassa Drury, Kristofer K. Rau, Mary Barlett Bunge, Lorne M. Mendell, Fred H. Gage, Richard D. Johnson, Caitlin E. Hill, Eric C. Rouchka, Lawrence D.F. Moon, Jeffrey C. Petruska

J Neurosci. 2016 Apr 13; 36(15): 4259–4275. doi: 10.1523/JNEUROSCI.2423-15.2016

PMCID:: PMC4829650

Abstract Article PDF–5.0M

Select item 476735818.

A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis

Haiyang Yu, Mykyta Artomov, Sebastian Brähler, M. Christine Stander, Ghaidan Shamsan, Matthew G. Sampson, J. Michael White, Matthias Kretzler, Jeffrey H. Miner, Sanjay Jain, Cheryl A. Winkler, Robi D. Mitra, Jeffrey B. Kopp, Mark J. Daly, Andrey S. Shaw

J Clin Invest. 2016 Mar 1; 126(3): 1067–1078. Published online 2016 Feb 22. doi: 10.1172/JCI82592

Correction in:: J Clin Invest. 2016 Apr 1; 126(4): 1603.

PMCID:: PMC4767358

Abstract Article PDF–1.4M

Select item 395324819.

CD2-associated Protein (CD2AP) Enhances Casitas B Lineage Lymphoma-3/c (Cbl-3/c)-mediated Ret Isoform-specific Ubiquitination and Degradation via Its Amino-terminal Src Homology 3 Domains

Gina N. Calco, Olivia R. Stephens, Laura M. Donahue, Cynthia C. Tsui, Brian A. Pierchala

J Biol Chem. 2014 Mar 14; 289(11): 7307–7319. Published online 2014 Jan 14. doi: 10.1074/jbc.M113.537878

PMCID:: PMC3953248

Abstract Article PDF–2.0M

Select item 144070820.

Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

Tobias B. Huber, Christopher Kwoh, Hui Wu, Katsuhiko Asanuma, Markus Gödel, Björn Hartleben, Ken J. Blumer, Jeffrey H. Miner, Peter Mundel, Andrey S. Shaw

J Clin Invest. 2006 May 1; 116(5): 1337–1345. Published online 2006 Apr 20. doi: 10.1172/JCI27400