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Select item 109725911.

CDK1 inhibition reduces osteogenesis in endothelial cells in vascular calcification

Yan Zhao, Yang Yang, Xiuju Wu, Li Zhang, Xinjiang Cai, Jaden Ji, Sydney Chen, Abigail Vera, Kristina I. Boström, Yucheng Yao

JCI Insight. 2024 Mar 8; 9(5): e176065. Published online 2024 Jan 23. doi: 10.1172/jci.insight.176065

PMCID:: PMC10972591

Abstract Article PDF–7.3M

Select item 109711502.

Long Non-Coding RNA-Cardiac-Inducing RNA 6 Mediates Repair of Infarcted Hearts by Inducing Mesenchymal Stem Cell Differentiation into Cardiogenic Cells through Cyclin-Dependent Kinase 1

Xiaotian Cui, Hui Dong, Shenghe Luo, Bingqi Zhuang, Yansheng Li, Chongning Zhong, Yuting Ma, Lan Hong

Int J Mol Sci. 2024 Mar; 25(6): 3466. Published online 2024 Mar 19. doi: 10.3390/ijms25063466

PMCID:: PMC10971150

Abstract Article PDF–12M

Select item 99073693.

Repurposing a Cyclin-Dependent Kinase 1 (CDK1) Mitotic Regulatory Network to Complete Terminal Differentiation in Lens Fiber Cells

Allen Taylor, Yumei Gu, Min-Lee Chang, Wenxin Yang, Sarah Francisco, Sheldon Rowan, Eloy Bejarano, Steven Pruitt, Liang Zhu, Grant Weiss, Lisa Brennan, Marc Kantorow, Elizabeth A. Whitcomb

Invest Ophthalmol Vis Sci. 2023 Feb; 64(2): 6. Published online 2023 Feb 3. doi: 10.1167/iovs.64.2.6

PMCID:: PMC9907369

Abstract Article PDF–2.6M

Select item 93170544.

A Potential Role of Cyclic Dependent Kinase 1 (CDK1) in Late Stage of Retinal Degeneration

Jiaming Zhou, Per Ekström

Cells. 2022 Jul; 11(14): 2143. Published online 2022 Jul 7. doi: 10.3390/cells11142143

PMCID:: PMC9317054

Abstract Article PDF–2.7M

Select item 72142185.

Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

Wojciech Michowski, Joel M. Chick, Chen Chu, Aleksandra Kolodziejczyk, Yichen Wang, Jan M. Suski, Brian Abraham, Lars Anders, Daniel Day, Lukas M. Dunkl, Mitchell Li Cheong Man, Tian Zhang, Phatthamon Laphanuwat, Nickolas A. Bacon, Lijun Liu, Anne Fassl, Samanta Sharma, Tobias Otto, Emanuelle Jecrois, Richard Han, Katharine E. Sweeney, Samuele Marro, Marius Wernig, Yan Geng, Alan Moses, Cheng Li, Steven P. Gygi, Richard A. Young, Piotr Sicinski

Mol Cell. Author manuscript; available in PMC 2021 May 7.

Published in final edited form as: Mol Cell. 2020 May 7; 78(3): 459–476.e13. Published online 2020 Apr 1. doi: 10.1016/j.molcel.2020.03.010

PMCID:: PMC7214218

Abstract Article PDF–2.8M

Select item 63021826.

Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone

Akira Takahashi, Mieradili Mulati, Masanori Saito, Hoashi Numata, Yutaka Kobayashi, Hiroki Ochi, Shingo Sato, Philipp Kaldis, Atsushi Okawa, Hiroyuki Inose

J Biol Chem. 2018 Dec 14; 293(50): 19387–19399. Published online 2018 Oct 26. doi: 10.1074/jbc.RA118.004834

PMCID:: PMC6302182

Abstract Article PDF–3.7M

Select item 61685597.

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

Zhe Wei, Jessica Greaney, Chenxi Zhou, Hayden A. Homer

Nat Commun. 2018; 9: 4029. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06510-9

PMCID:: PMC6168559

Abstract Article PDF–2.5M

Select item 48161598.

The Indispensable Role of Cyclin-Dependent Kinase 1 in Skeletal Development

Masanori Saito, Mieradili Mulati, S. Zakiah A. Talib, Philipp Kaldis, Shu Takeda, Atsushi Okawa, Hiroyuki Inose

Sci Rep. 2016; 6: 20622. Published online 2016 Feb 10. doi: 10.1038/srep20622

PMCID:: PMC4816159

Abstract Article PDF–1.5M

Select item 47126969.

Disrupting Cyclin Dependent Kinase 1 in Spermatocytes Causes Late Meiotic Arrest and Infertility in Mice

Tracy M. Clement, Amy L. Inselman, Eugenia H. Goulding, William D. Willis, Edward M. Eddy

Biol Reprod. 2015 Dec; 93(6): 137. Published online 2015 Oct 21. doi: 10.1095/biolreprod.115.134940

PMCID:: PMC4712696

Abstract Article PDF–1.1M

Select item 399879410.

Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity

Ibtissem Nabti, Petros Marangos, Jenny Bormann, Nobuaki R. Kudo, John Carroll

J Cell Biol. 2014 Mar 17; 204(6): 891–900. doi: 10.1083/jcb.201305049

PMCID:: PMC3998794

Abstract Article PDF–2.4M

Select item 371897011.

Increased CDK1 activity determines the timing of kinetochore-microtubule attachments in meiosis I

Olga Davydenko, Richard M. Schultz, Michael A. Lampson

J Cell Biol. 2013 Jul 22; 202(2): 221–229. doi: 10.1083/jcb.201303019

PMCID:: PMC3718970

Abstract Article PDF–2.3M

Select item 112912312.

Genomewide production of multipurpose alleles for the functional analysis of the mouse genome

Frank Schnütgen, Silke De-Zolt, Petra Van Sloun, Melanie Hollatz, Thomas Floss, Jens Hansen, Joachim Altschmied, Claudia Seisenberger, Norbert B. Ghyselinck, Patricia Ruiz, Pierre Chambon, Wolfgang Wurst, Harald von Melchner

Proc Natl Acad Sci U S A. 2005 May 17; 102(20): 7221–7226. Published online 2005 May 3. doi: 10.1073/pnas.0502273102

PMCID:: PMC1129123

Abstract Article PDF–595K

Select item 1016254313.

Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice

Rui Sun, Siying Guo, Yoko Shuda, Anish B. Chakka, Lora H. Rigatti, Guangyi Zhao, Mohammed A. E. Ali, Christopher Y. Park, Uma Chandran, Jian Yu, Christopher J. Bakkenist, Masahiro Shuda, Patrick S. Moore, Yuan Chang

PLoS One. 2023; 18(5): e0282722. Published online 2023 May 5. doi: 10.1371/journal.pone.0282722

PMCID:: PMC10162543

Abstract Article PDF–1.3M

Select item 1009445414.

Tceal7 Regulates Skeletal Muscle Development through Its Interaction with Cdk1

Zhenzhen Xiong, Mengni Wang, Jianhua Wu, Xiaozhong Shi

Int J Mol Sci. 2023 Apr; 24(7): 6264. Published online 2023 Mar 27. doi: 10.3390/ijms24076264

PMCID:: PMC10094454

Abstract Article PDF–3.9M

Select item 777196815.

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

Jin Rong Ow, Matias J Caldez, Gözde Zafer, Juat Chin Foo, Hong Yu Li, Soumita Ghosh, Heike Wollmann, Amaury Cazenave-Gassiot, Chee Bing Ong, Markus R Wenk, Weiping Han, Hyungwon Choi, Philipp Kaldis

eLife. 2020; 9: e63835. Published online 2020 Dec 21. doi: 10.7554/eLife.63835

PMCID:: PMC7771968

Abstract Article PDF–4.8M

Select item 759163516.

Cyclin-Dependent Kinase 1 Is Essential for Muscle Regeneration and Overload Muscle Fiber Hypertrophy

Yutaka Kobayashi, Tomoyuki Tanaka, Mieradilli Mulati, Hiroki Ochi, Shingo Sato, Philipp Kaldis, Toshitaka Yoshii, Atsushi Okawa, Hiroyuki Inose

Front Cell Dev Biol. 2020; 8: 564581. Published online 2020 Oct 14. doi: 10.3389/fcell.2020.564581

PMCID:: PMC7591635

Abstract Article PDF–6.4M

Select item 606184117.

Cyclin-dependent kinase 1 activity coordinates the chromatin associated state of Oct4 during cell cycle in embryonic stem cells

Hye Ji Kim, Jihoon Shin, Sangho Lee, Tae Wan Kim, Hyonchol Jang, Min Young Suh, Jae-Hwan Kim, In-Young Hwang, Deog Su Hwang, Eun-Jung Cho, Hong-Duk Youn

Nucleic Acids Res. 2018 Jul 27; 46(13): 6544–6560. Published online 2018 Jun 13. doi: 10.1093/nar/gky371

PMCID:: PMC6061841

Abstract Article PDF–2.3M

Select item 585683918.

Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death

Quentin Marlier, Florian Jibassia, Sébastien Verteneuil, Jérôme Linden, Philipp Kaldis, Laurent Meijer, Laurent Nguyen, Renaud Vandenbosch, Brigitte Malgrange

Cell Death Discov. 2018; 4: 43. Published online 2018 Mar 16. doi: 10.1038/s41420-018-0044-7

PMCID:: PMC5856839

Abstract Article PDF–4.4M

Select item 509986819.

Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan

Deepak Adhikari, Kiran Busayavalasa, Jingjing Zhang, Mengwen Hu, Sanjiv Risal, Mustafa Bilal Bayazit, Meenakshi Singh, M Kasim Diril, Philipp Kaldis, Kui Liu

Cell Res. 2016 Nov; 26(11): 1212–1225. Published online 2016 Oct 21. doi: 10.1038/cr.2016.119

PMCID:: PMC5099868

Abstract Article PDF–4.3M

Select item 490799920.

Oxidative stress-induced DNA damage of mouse zygotes triggers G2/M checkpoint and phosphorylates Cdc25 and Cdc2

Yuting Zhang, Diting Qian, Zhiling Li, Yue Huang, Que Wu, Gaizhen Ru, Man Chen, Bin Wang

Cell Stress Chaperones. 2016 Jul; 21(4): 687–696. Published online 2016 Apr 26. doi: 10.1007/s12192-016-0693-5

PMCID:: PMC4907999

Abstract Article PDF–971K

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