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Select item 111427401.

Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft-versus-host disease

Alison Moe, Aditya Rayasam, Garrett Sauber, Ravi K. Shah, Ashley Doherty, Cheng-Yin Yuan, Aniko Szabo, Bob M. Moore, II, Marco Colonna, Weiguo Cui, Julian Romero, Anthony E. Zamora, Cecilia J. Hillard, William R. Drobyski

J Clin Invest. 2024 Jun 3; 134(11): e175205. Published online 2024 Apr 25. doi: 10.1172/JCI175205

PMCID:: PMC11142740

Abstract Article PDF–12M

Select item 109678192.

Activation of Cannabinoid Type 2 Receptor in Microglia Reduces Neuroinflammation through Inhibiting Aerobic Glycolysis to Relieve Hypertension

Ruohan Shan, Yuxiang Zhang, Yiping Shi, Xiaowen Wang, Xueke Wang, Guanying Ma, Qian Li

Biomolecules. 2024 Mar; 14(3): 333. Published online 2024 Mar 11. doi: 10.3390/biom14030333

PMCID:: PMC10967819

Abstract Article PDF–4.4M

Select item 107681423.

The role of cannabinoid receptor 2 in bone remodeling during orthodontic tooth movement

Deng-ying Fan, Hao-yan Zhai, Yuan Zhao, Xing Qiao, De-chao Zhu, Hui-Juan Liu, Chunyan Liu

BMC Oral Health. 2024; 24: 23. Published online 2024 Jan 4. doi: 10.1186/s12903-023-03810-5

PMCID:: PMC10768142

Abstract Article PDF–1.9M

Select item 107437884.

Role of the CB2 Cannabinoid Receptor in the Regulation of Food Intake: A Systematic Review

Luis Miguel Rodríguez-Serrano, María Elena Chávez-Hernández

Int J Mol Sci. 2023 Dec; 24(24): 17516. Published online 2023 Dec 15. doi: 10.3390/ijms242417516

PMCID:: PMC10743788

Abstract Article PDF–21M

Select item 103331775.

Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation

Bolanle Fatimat Olabiyi, Anne-Caroline Schmoele, Eva Carolina Beins, Andreas Zimmer

Sci Rep. 2023; 13: 11105. Published online 2023 Jul 10. doi: 10.1038/s41598-023-37702-z

Correction in:: Sci Rep. 2023; 13: 15699.

PMCID:: PMC10333177

Abstract Article PDF–1.9M

Select item 101784566.

The Anti-Tumorigenic Role of Cannabinoid Receptor 2 in Non-Melanoma Skin Cancer

Jennifer Ana Iden, Bitya Raphael-Mizrahi, Aaron Naim, Albert Kolomansky, Tamar Liron, Drorit Neumann, Marilena Vered, Yankel Gabet

Int J Mol Sci. 2023 May; 24(9): 7773. Published online 2023 Apr 24. doi: 10.3390/ijms24097773

PMCID:: PMC10178456

Abstract Article PDF–2.6M

Select item 100177097.

Structural basis of selective cannabinoid CB₂ receptor activation

Xiaoting Li, Hao Chang, Jara Bouma, Laura V. de Paus, Partha Mukhopadhyay, Janos Paloczi, Mohammed Mustafa, Cas van der Horst, Sanjay Sunil Kumar, Lijie Wu, Yanan Yu, Richard J. B. H. N. van den Berg, Antonius P. A. Janssen, Aron Lichtman, Zhi-Jie Liu, Pal Pacher, Mario van der Stelt, Laura H. Heitman, Tian Hua

Nat Commun. 2023; 14: 1447. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37112-9

PMCID:: PMC10017709

Abstract Article PDF–4.0M

Select item 99285578.

Update on the controversial identity of cells expressing cnr2 gene in the nervous system

Wanda Grabon, Jacques Bodennec, Sylvain Rheims, Amor Belmeguenai, Laurent Bezin

CNS Neurosci Ther. 2023 Mar; 29(3): 760–770. Published online 2023 Jan 5. doi: 10.1111/cns.13977

PMCID:: PMC9928557

Abstract Article PDF–1.3M

Select item 98451809.

Peripheral sensory neuron CB2 cannabinoid receptors are necessary for both CB2-mediated antinociceptive efficacy and sparing of morphine tolerance in a mouse model of anti-retroviral toxic neuropathy

Lawrence M. Carey, Zhili Xu, Gabriela Rajic, Alexandros Makriyannis, Julian Romero, Cecilia Hillard, Ken Mackie, Andrea G. Hohmann

Pharmacol Res. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Pharmacol Res. 2023 Jan; 187: 106560. Published online 2022 Nov 20. doi: 10.1016/j.phrs.2022.106560

PMCID:: PMC9845180

Abstract Article PDF–2.5M

Select item 901372810.

Cannabinoid Receptor II engagement promotes ILC2 expansion and enhances ILC2-dependent airway hyperreactivity

Benjamin P. Hurrell, Doumet Georges Helou, Pedram Shafiei-Jahani, Emily Howard, Jacob D. Painter, Christine Quach, Omid Akbari

J Allergy Clin Immunol. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: J Allergy Clin Immunol. 2022 May; 149(5): 1628–1642.e10. Published online 2021 Oct 18. doi: 10.1016/j.jaci.2021.09.037

PMCID:: PMC9013728

Abstract Article PDF–1.5M

Select item 899022811.

Electroacupuncture Reduces Visceral Pain Via Cannabinoid CB2 Receptors in a Mouse Model of Inflammatory Bowel Disease

Hong Zhang, Wei He, Xue-Fei Hu, Yan-Zhen Li, Yong-Min Liu, Wen-Qiang Ge, Ou-Yang Zhanmu, Chao Chen, Yu-Ye Lan, Yang-Shuai Su, Xiang-Hong Jing, Bing Zhu, Hui-Lin Pan, Ling-Ling Yu, Man Li

Front Pharmacol. 2022; 13: 861799. Published online 2022 Mar 25. doi: 10.3389/fphar.2022.861799

PMCID:: PMC8990228

Abstract Article PDF–6.0M

Select item 898108812.

CB2R Activation Regulates TFEB-Mediated Autophagy and Affects Lipid Metabolism and Inflammation of Astrocytes in POCD

Lieliang Zhang, Xifeng Wang, Wen Yu, Jun Ying, Pu Fang, Qingcui Zheng, Xiaojin Feng, Jialing Hu, Fan Xiao, Shoulin Chen, Gen Wei, Yue Lin, Xing Liu, Danying Yang, Yang Fang, Guohai Xu, Fuzhou Hua

Front Immunol. 2022; 13: 836494. Published online 2022 Mar 22. doi: 10.3389/fimmu.2022.836494

PMCID:: PMC8981088

Abstract Article PDF–11M

Select item 894287113.

A peripheral CB₂ cannabinoid receptor mechanism suppresses chemotherapy-induced peripheral neuropathy: evidence from a CB₂ reporter mouse

Xiaoyan Lin, Zhili Xu, Lawrence Carey, Julian Romero, Alexandros Makriyannis, Cecilia J. Hillard, Elizabeth Ruggiero, Marilyn Dockum, George Houk, Ken Mackie, Phillip J. Albrecht, Frank L. Rice, Andrea G. Hohmann

Pain. 2022 May; 163(5): 834–851. Published online 2021 Sep 24. doi: 10.1097/j.pain.0000000000002502

PMCID:: PMC8942871

Abstract Article PDF–1.6M

Select item 870025014.

The Neuroprotective Effects of the CB2 Agonist GW842166x in the 6-OHDA Mouse Model of Parkinson’s Disease

Hao Yu, Xiaojie Liu, Bixuan Chen, Casey R. Vickstrom, Vladislav Friedman, Thomas J. Kelly, Xiaowen Bai, Li Zhao, Cecilia J. Hillard, Qing-Song Liu

Cells. 2021 Dec; 10(12): 3548. Published online 2021 Dec 16. doi: 10.3390/cells10123548

PMCID:: PMC8700250

Abstract Article PDF–2.0M

Select item 851309715.

Cannabinoid Receptor 2 Alters Social Memory and Microglial Activity in an Age-Dependent Manner

Joanna Agnieszka Komorowska-Müller, Tanushka Rana, Bolanle Fatimat Olabiyi, Andreas Zimmer, Anne-Caroline Schmöle

Molecules. 2021 Oct; 26(19): 5984. Published online 2021 Oct 2. doi: 10.3390/molecules26195984

PMCID:: PMC8513097

Abstract Article PDF–1.2M

Select item 837689316.

Cannabinoid receptor 2 deletion influences social memory and synaptic architecture in the hippocampus

Joanna Agnieszka Komorowska-Müller, Kishore Aravind Ravichandran, Andreas Zimmer, Britta Schürmann

Sci Rep. 2021; 11: 16828. Published online 2021 Aug 19. doi: 10.1038/s41598-021-96285-9

PMCID:: PMC8376893

Abstract Article PDF–11M

Select item 793376917.

Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease

Cheng Yin Yuan, Vivian Zhou, Garrett Sauber, Todd Stollenwerk, Richard Komorowski, Alicia López, Rosa María Tolón, Julian Romero, Cecilia J. Hillard, William R. Drobyski

Blood. 2021 Mar 4; 137(9): 1241–1255. Prepublished online 2020 Oct 7. doi: 10.1182/blood.2020004871