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Items: 1 to 20 of 129

1.
HSPB5 suppresses renal inflammation and protects lupus-prone NZB/W F1 mice from severe renal damage
Justin Knapp, Marsela Braunstein, Spencer Iner Thomas Berg, Cody Shirriff
Arthritis Res Ther. 2022; 24: 267. Published online 2022 Dec 12. doi: 10.1186/s13075-022-02958-9
PMCID:
PMC9743758
AbstractArticlePDF–3.3M
2.
Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury
Erin-Mai F. Lim, Vahid Hoghooghi, Kathleen M. Hagen, Kunal Kapoor, Ariana Frederick, Trisha M. Finlay, Shalina S. Ousman
J Neuroinflammation. 2021; 18: 82. Published online 2021 Mar 24. doi: 10.1186/s12974-021-02108-z
PMCID:
PMC7992798
AbstractArticlePDF–5.6M
3.
αB-Crystallin Alleviates Endotoxin-Induced Retinal Inflammation and Inhibits Microglial Activation and Autophagy
Fangyu Wang, Zhaoxin Jiang, Bingsheng Lou, Fang Duan, Suo Qiu, Zhixing Cheng, Xinqi Ma, Yao Yang, Xiaofeng Lin
Front Immunol. 2021; 12: 641999. Published online 2021 Mar 11. doi: 10.3389/fimmu.2021.641999
PMCID:
PMC7991093
AbstractArticlePDF–3.2M
4.
Mechanism of Action of VP1-001 in cryAB(R120G)-Associated and Age-Related Cataracts
Kathleen S. Molnar, Bryan M. Dunyak, Bonnie Su, Yevgeniy Izrayelit, Brittney McGlasson-Naumann, Paul D. Hamilton, Mingxing Qian, Douglas F. Covey, Jason E. Gestwicki, Leah N. Makley, Usha P. Andley
Invest Ophthalmol Vis Sci. 2019 Aug; 60(10): 3320–3331. doi: 10.1167/iovs.18-25647
PMCID:
PMC6676924
AbstractArticlePDF–1.8M
5.
The Small Heat Shock Protein α-Crystallin B Shows Neuroprotective Properties in a Glaucoma Animal Model
Fabian Anders, Aiwei Liu, Carolina Mann, Julia Teister, Jasmin Lauzi, Solon Thanos, Franz H. Grus, Norbert Pfeiffer, Verena Prokosch
Int J Mol Sci. 2017 Nov; 18(11): 2418. Published online 2017 Nov 14. doi: 10.3390/ijms18112418
PMCID:
PMC5713386
AbstractArticlePDF–3.6M
6.
Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice
Laura A. N. Peferoen, Marjolein Breur, Sarah van de Berg, Regina Peferoen‐Baert, Erik H. W. G. M. Boddeke, Paul van der Valk, Gareth Pryce, Johannes M. van Noort, David Baker, Sandra Amor
Immunology. 2016 Oct; 149(2): 146–156. Published online 2016 Aug 9. doi: 10.1111/imm.12644
PMCID:
PMC5011681
AbstractArticlePDF–1.0M
7.
αB-crystallin is essential for the TGF-β2-mediated epithelial to mesenchymal transition of lens epithelial cells
Rooban B. Nahomi, Mina B. Pantcheva, Ram H. Nagaraj
Biochem J. Author manuscript; available in PMC 2016 Jun 30.
Published in final edited form as: Biochem J. 2016 May 15; 473(10): 1455–1469. Published online 2016 Mar 17. doi: 10.1042/BCJ20160128
PMCID:
PMC4928857
AbstractArticlePDF–2.4M
8.
Pharmacological Chaperone for Alpha-Crystallin Partially Restores Transparency in Cataract Models
Leah N. Makley, Kathryn A. McMenimen, Brian T. DeVree, Joshua W. Goldman, Brittney N. McGlasson, Ponni Rajagopal, Bryan M. Dunyak, Thomas J. McQuade, Andrea D. Thompson, Roger Sunahara, Rachel E. Klevit, Usha P. Andley, Jason E. Gestwicki
Science. Author manuscript; available in PMC 2016 Nov 6.
Published in final edited form as: Science. 2015 Nov 6; 350(6261): 674–677. doi: 10.1126/science.aac9145
PMCID:
PMC4725592
AbstractArticlePDF–431K
9.
Protection of Retina by αB Crystallin in Sodium Iodate Induced Retinal Degeneration
Peng Zhou, Ram Kannan, Christine Spee, Parameswaran G. Sreekumar, Guorui Dou, David R. Hinton
PLoS One. 2014; 9(5): e98275. Published online 2014 May 29. doi: 10.1371/journal.pone.0098275
PMCID:
PMC4038555
AbstractArticlePDF–2.4M
10.
α-Crystallin B prevents apoptosis after H2O2 exposure in mouse neonatal cardiomyocytes
Roxana Chis, Parveen Sharma, Nicolas Bousette, Tetsuaki Miyake, Aaron Wilson, Peter H. Backx, Anthony O. Gramolini
Am J Physiol Heart Circ Physiol. Author manuscript; available in PMC 2013 Jul 9.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2012 Oct 15; 303(8): H967–H978. Published online 2012 Aug 17. doi: 10.1152/ajpheart.00040.2012
PMCID:
PMC3706333
AbstractArticlePDF–1.9M
11.
αB-Crystallin regulates expansion of CD11b+Gr-1+ immature myeloid cells during tumor progression
Lothar C. Dieterich, Petter Schiller, Hua Huang, Eric F. Wawrousek, Angelica Loskog, Alkwin Wanders, Lieve Moons, Anna Dimberg
FASEB J. 2013 Jan; 27(1): 151–162. doi: 10.1096/fj.12-213017
PMCID:
PMC3528311
AbstractArticle
12.
Therapeutic Effects of Systemic Administration of Chaperone αB-Crystallin Associated with Binding Proinflammatory Plasma Proteins
Jonathan B. Rothbard, Michael P. Kurnellas, Sara Brownell, Chris M. Adams, Leon Su, Robert C. Axtell, Rong Chen, C. Garrison Fathman, William H. Robinson, Lawrence Steinman
J Biol Chem. 2012 Mar 23; 287(13): 9708–9721. Published online 2012 Feb 3. doi: 10.1074/jbc.M111.337691
PMCID:
PMC3322989
AbstractArticlePDF–2.2M
13.
Cardioprotective Effect of Nicorandil, a Mitochondrial ATP-Sensitive Potassium Channel Opener, Prolongs Survival in HSPB5 R120G Transgenic Mice
Atsushi Sanbe, Tetsuro Marunouchi, Junji Yamauchi, Kouichi Tanonaka, Hideo Nishigori, Akito Tanoue
PLoS One. 2011; 6(4): e18922. Published online 2011 Apr 25. doi: 10.1371/journal.pone.0018922
PMCID:
PMC3081834
AbstractArticlePDF–1.0M
14.
A Knock-In Mouse Model for the R120G Mutation of αB-Crystallin Recapitulates Human Hereditary Myopathy and Cataracts
Usha P. Andley, Paul D. Hamilton, Nathan Ravi, Conrad C. Weihl
PLoS One. 2011; 6(3): e17671. Published online 2011 Mar 18. doi: 10.1371/journal.pone.0017671
PMCID:
PMC3060869
AbstractArticlePDF–809K
15.
Kinetics of the translocation and phosphorylation of αB-crystallin in mouse heart mitochondria during ex vivo ischemia
R. Whittaker, M. S. Glassy, N. Gude, M. A. Sussman, R. A. Gottlieb, C. C. Glembotski
Am J Physiol Heart Circ Physiol. 2009 May; 296(5): H1633–H1642. Published online 2009 Feb 27. doi: 10.1152/ajpheart.01227.2008
PMCID:
PMC2685329
AbstractArticle
16.
Tissue-specific activity of the blind mole rat and the two nucleotide-mutated mouse αB-crystallin promoter in transgenic mice
Yan Li, R. Barry Hough, Joram Piatigorsky
Proc Natl Acad Sci U S A. 2007 Feb 20; 104(8): 2608–2613. Published online 2007 Feb 9. doi: 10.1073/pnas.0611684104
PMCID:
PMC1796782
AbstractArticlePDF–1.0M
17.
Mitochondrial Dysfunction and Apoptosis Underlie the Pathogenic Process in Alpha-B-Crystallin Desmin Related Cardiomyopathy
Alina Maloyan, Atsushi Sanbe, Hanna Osinska, Margaret Westfall, Dustin Robinson, Ken-ichi Imahashi, Elizabeth Murphy, Jeffrey Robbins
Circulation. Author manuscript; available in PMC 2006 May 29.
Published in final edited form as: Circulation. 2005 Nov 29; 112(22): 3451–3461. doi: 10.1161/CIRCULATIONAHA.105.572552
PMCID:
PMC1398051
AbstractArticlePDF–1.6M
18.
Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy
Atsushi Sanbe, Hanna Osinska, Chet Villa, James Gulick, Raisa Klevitsky, Charles G. Glabe, Rakez Kayed, Jeffrey Robbins
Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38): 13592–13597. Published online 2005 Sep 9. doi: 10.1073/pnas.0503324102
PMCID:
PMC1224623
AbstractArticlePDF–880K
19.
Identification of a lens-specific regulatory region (LSR) of the murine alpha B-crystallin gene.
R Gopal-Srivastava, J Piatigorsky
Nucleic Acids Res. 1994 Apr 11; 22(7): 1281–1286. doi: 10.1093/nar/22.7.1281
PMCID:
PMC523654
SummaryPage BrowsePDF–1.2M
20.
Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis
Atsushi Sanbe, Hanna Osinska, Jeffrey E. Saffitz, Charles G. Glabe, Rakez Kayed, Alina Maloyan, Jeffrey Robbins
Proc Natl Acad Sci U S A. 2004 Jul 6; 101(27): 10132–10136. Published online 2004 Jun 25. doi: 10.1073/pnas.0401900101
PMCID:
PMC454177
AbstractArticlePDF–902K

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