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Items: 1 to 20 of 44

1.
Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity
Wan-Hui Liao, Claudia Suendermann, Andrea Eva Steuer, Gustavo Pacheco Lopez, Alex Odermatt, Nourdine Faresse, Maciej Henneberg, Wolfgang Langhans
JCI Insight. 2018 Jul 26; 3(14): e99015. Published online 2018 Jul 26. doi: 10.1172/jci.insight.99015
PMCID:
PMC6124420
AbstractArticlePDF–6.9M
2.
Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice
P. Luo, A. Dematteo, Z. Wang, L. Zhu, A. Wang, H.-S. Kim, A. Pozzi, J. M. Stafford, J. M. Luther
Diabetologia. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: Diabetologia. 2013 Apr; 56(4): 901–910. Published online 2013 Jan 12. doi: 10.1007/s00125-012-2814-8
PMCID:
PMC3593801
AbstractArticlePDF–1.7M
3.
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury
James M. Luther, Pengcheng Luo, Zuofei Wang, Samuel E. Cohen, Hyung-Suk Kim, Agnes B. Fogo, Nancy J. Brown
Kidney Int. Author manuscript; available in PMC 2013 Mar 1.
Published in final edited form as: Kidney Int. 2012 Sep; 82(6): 643–651. Published online 2012 May 23. doi: 10.1038/ki.2012.170
PMCID:
PMC3434275
AbstractArticlePDF–2.0M
4.
Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets
J. M. Luther, P. Luo, M. T. Kreger, M. Brissova, C. Dai, T. T. Whitfield, H. S. Kim, D. H. Wasserman, A. C. Powers, N. J. Brown
Diabetologia. Author manuscript; available in PMC 2012 Aug 1.
Published in final edited form as: Diabetologia. 2011 Aug; 54(8): 2152–2163. Published online 2011 Apr 26. doi: 10.1007/s00125-011-2158-9
PMCID:
PMC3216479
AbstractArticlePDF–1.3M
5.
Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior
Hannah M Costello, G Ryan Crislip, Kit-Yan Cheng, I Jeanette Lynch, Alexandria Juffre, Phillip Bratanatawira, Annalisse Mckee, Ryanne S Thelwell, Victor M Mendez, Charles S Wingo, Lauren G Douma, Michelle L Gumz
Function (Oxf) 2023; 4(2): zqad001. Published online 2023 Jan 9. doi: 10.1093/function/zqad001
PMCID:
PMC9909366
AbstractArticlePDF–6.4M
6.
Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
Mitchell H. Omar, Dominic P. Byrne, Kiana N. Jones, Tyler M. Lakey, Kerrie B. Collins, Kyung-Soon Lee, Leonard A. Daly, Katherine A. Forbush, Ho-Tak Lau, Martin Golkowski, G. Stanley McKnight, David T. Breault, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Claire E. Eyers, Geoffrey S. Baird, Shao-En Ong, F. Donelson Smith, Patrick A. Eyers, John D. Scott
Cell Rep. Author manuscript; available in PMC 2022 Jul 25.
Published in final edited form as: Cell Rep. 2022 Jul 12; 40(2): 111073. doi: 10.1016/j.celrep.2022.111073
PMCID:
PMC9311266
AbstractArticlePDF–3.4M
7.
Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice
Brahmaraju Mopidevi, Indu Sivankutty, Shoujin Hao, Nicholas R. Ferreri, Ashok Kumar
J Biol Chem. 2020 Aug 7; 295(32): 11068–11081. Published online 2020 Jun 15. doi: 10.1074/jbc.RA120.013047
PMCID:
PMC7415971
AbstractArticlePDF–3.5M
8.
Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
Nick A. Guagliardo, Peter M. Klein, Christina A. Gancayco, Adam Lu, Sining Leng, Rany R. Makarem, Chelsea Cho, Craig G. Rusin, David T. Breault, Paula Q. Barrett, Mark P. Beenhakker
Nat Commun. 2020; 11: 1679. Published online 2020 Apr 3. doi: 10.1038/s41467-020-15408-4
PMCID:
PMC7125102
AbstractArticlePDF–4.0M
9.
Antiaging Gene Klotho Regulates Adrenal CYP11B2 Expression and Aldosterone Synthesis
Xiaoli Zhou, Kai Chen, Yongjun Wang, Mariano Schuman, Han Lei, Zhongjie Sun
J Am Soc Nephrol. 2016 Jun; 27(6): 1765–1776. Published online 2015 Oct 15. doi: 10.1681/ASN.2015010093
PMCID:
PMC4884100
AbstractArticle
10.
Aldosterone Postnatally, but not at Birth, Is Required for Optimal Induction of Renal Mineralocorticoid Receptor Expression and Sodium Reabsorption
Laetitia Martinerie, Say Viengchareun, Geri Meduri, Hyung-Suk Kim, James M. Luther, Marc Lombès
Endocrinology. 2011 Jun; 152(6): 2483–2491. Published online 2011 Apr 5. doi: 10.1210/en.2010-1460
PMCID:
PMC3100620
AbstractArticle
11.
Tissue kallikrein permits early renal adaptation to potassium load
Soumaya El Moghrabi, Pascal Houillier, Nicolas Picard, Fabien Sohet, Bharath Wootla, May Bloch-Faure, Françoise Leviel, Lydie Cheval, Sebastian Frische, Pierre Meneton, Dominique Eladari, Régine Chambrey
Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30): 13526–13531. Published online 2010 Jul 12. doi: 10.1073/pnas.0913070107
PMCID:
PMC2922146
AbstractArticlePDF–253K
12.
Adrenal Abcg1 Controls Cholesterol Flux and Steroidogenesis
Jani Liimatta, Evelyn Curschellas, Emre Murat Altinkilic, Rawda Naamneh Elzenaty, Philipp Augsburger, Therina du Toit, Clarissa D Voegel, David T Breault, Christa E Flück, Emanuele Pignatti
Endocrinology. 2024 Mar; 165(3): bqae014. Published online 2024 Feb 1. doi: 10.1210/endocr/bqae014
PMCID:
PMC10863561
AbstractArticle
13.
Calcineurin regulates aldosterone production via dephosphorylation of NFATC4
Mesut Berber, Sining Leng, Agnieszka Wengi, Denise V. Winter, Alex Odermatt, Felix Beuschlein, Johannes Loffing, David T. Breault, David Penton
JCI Insight. 2023 Jul 24; 8(14): e157027. Published online 2023 Jul 24. doi: 10.1172/jci.insight.157027
PMCID:
PMC10443813
AbstractArticlePDF–1.6M
14.
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A. Youssef, Alain de Bruin, Elvira R. M. Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl
Dis Model Mech. 2023 Jun 1; 16(6): dmm050053. Published online 2023 May 10. doi: 10.1242/dmm.050053
PMCID:
PMC10184674
AbstractArticle
15.
Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation
Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. Breault
Cell Rep. Author manuscript; available in PMC 2020 Jun 9.
Published in final edited form as: Cell Rep. 2020 Apr 21; 31(3): 107524. doi: 10.1016/j.celrep.2020.107524
PMCID:
PMC7281829
AbstractArticlePDF–3.3M
16.
β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
Sining Leng, Emanuele Pignatti, Radhika S. Khetani, Manasvi S. Shah, Simiao Xu, Ji Miao, Makoto M. Taketo, Felix Beuschlein, Paula Q. Barrett, Diana L. Carlone, David T. Breault
Nat Commun. 2020; 11: 1680. Published online 2020 Apr 3. doi: 10.1038/s41467-020-15332-7
PMCID:
PMC7125176
AbstractArticlePDF–43M
17.
β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
Dipika R. Mohan, Kleiton S. Borges, Isabella Finco, Christopher R. LaPensee, Juilee Rege, April L. Solon, Donald W. Little, III, Tobias Else, Madson Q. Almeida, Derek Dang, James Haggerty-Skeans, April A. Apfelbaum, Michelle Vinco, Alda Wakamatsu, Beatriz M. P. Mariani, Larissa Costa Amorim, Ana Claudia Latronico, Berenice B. Mendonca, Maria Claudia N. Zerbini, Elizabeth R. Lawlor, Ryoma Ohi, Richard J. Auchus, William E. Rainey, Suely K. N. Marie, Thomas J. Giordano, Sriram Venneti, Maria Candida Barisson Villares Fragoso, David T. Breault, Antonio Marcondes Lerario, Gary D. Hammer
Cancer Res. Author manuscript; available in PMC 2024 Jan 5.
Published in final edited form as: Cancer Res. 2023 Jul 5; 83(13): 2123–2141. doi: 10.1158/0008-5472.CAN-22-2712
PMCID:
PMC10330305
AbstractArticlePDF–4.4M
18.
Sex Differences in Adrenal Bmal1 Deletion–Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice
William C Engeland, Logan Massman, Lauren Miller, Sining Leng, Emanuele Pignatti, Lorena Pantano, Diana L Carlone, Paulo Kofuji, David T Breault
Endocrinology. 2019 Oct; 160(10): 2215–2229. Published online 2019 Jul 29. doi: 10.1210/en.2019-00357
PMCID:
PMC6735739
AbstractArticle
19.
Adrenal tissue-specific deletion of TASK channels causes aldosterone-driven Angiotensin II-independent hypertension.
Nick A. Guagliardo, Junlan Yao, Eric J. Stipes, Sylvia Cechova, Thu H. Le, Douglas A. Bayliss, David T. Breault, Paula Q. Barrett
Hypertension. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: Hypertension. 2019 Feb; 73(2): 407–414. doi: 10.1161/HYPERTENSIONAHA.118.11962
PMCID:
PMC6326871
AbstractArticlePDF–711K
20.
The Adrenal Clock Prevents Aberrant Light-Induced Alterations in Circadian Glucocorticoid Rhythms
William C Engeland, Logan Massman, Shubhendu Mishra, J Marina Yoder, Sining Leng, Emanuele Pignatti, Mary E Piper, Diana L Carlone, David T Breault, Paulo Kofuji
Endocrinology. 2018 Dec; 159(12): 3950–3964. Published online 2018 Oct 12. doi: 10.1210/en.2018-00769
PMCID:
PMC6240903
AbstractArticle

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