PMC Links for Gene (Select 13112) - PMC

Yong Wang, Hai-Hong Hu, Hao Pang, Xiao-Yang Zhou, Lu-Shan Yu, Lu-Lu Wang, Cang'e Liu, Ke-Nan Guo, Cong Zhao, Qin Liu, Ben-Hua Zeng, Huan Tang, Hai-Tao Shang, Su Zeng, Hong Wei

PLoS One. 2012; 7(1): e30560. Published online 2012 Jan 24. doi: 10.1371/journal.pone.0030560

PMCID:: PMC3265487

Abstract Article PDF–1012K

Select item 30615594.

CYP3A-Mediated Generation of Aldehyde and Hydrazine in Atazanavir Metabolism

Feng Li, Jie Lu, Laiyou Wang, Xiaochao Ma

Drug Metab Dispos. 2011 Mar; 39(3): 394–401. doi: 10.1124/dmd.110.036327

PMCID:: PMC3061559

Abstract Article PDF–1.9M

Select item 94370395.

Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism

Shotaro Uehara, Yuichi Iida, Miyuki Ida-Tanaka, Motohito Goto, Kenji Kawai, Masafumi Yamamoto, Yuichiro Higuchi, Satoshi Ito, Riichi Takahashi, Hidetaka Kamimura, Mamoru Ito, Hiroshi Yamazaki, Mitsuo Oshimura, Yasuhiro Kazuki, Hiroshi Suemizu

Sci Rep. 2022; 12: 14907. Published online 2022 Sep 1. doi: 10.1038/s41598-022-19242-0

PMCID:: PMC9437039

Abstract Article PDF–2.0M

Select item 67958956.

Bmal1 regulates circadian expression of cytochrome P450 3a11 and drug metabolism in mice

Yanke Lin, Shuai Wang, Ziyue Zhou, Lianxia Guo, Fangjun Yu, Baojian Wu

Commun Biol. 2019; 2: 378. Published online 2019 Oct 16. doi: 10.1038/s42003-019-0607-z

PMCID:: PMC6795895

Abstract Article PDF–1.9M

Select item 43348157.

Schisandrol B Protects Against Acetaminophen-Induced Hepatotoxicity by Inhibition of CYP-Mediated Bioactivation and Regulation of Liver Regeneration

Yiming Jiang, Xiaomei Fan, Ying Wang, Pan Chen, Hang Zeng, Huasen Tan, Frank J. Gonzalez, Min Huang, Huichang Bi

Toxicol Sci. 2015 Jan; 143(1): 107–115. Published online 2014 Oct 14. doi: 10.1093/toxsci/kfu216

PMCID:: PMC4334815

Abstract Article PDF–822K

Select item 37813738.

Downregulation of Mouse Hepatic CYP3A Protein by 3-Methylcholanthrene Does Not Require Cytochrome P450-Dependent Metabolism

Chunja Lee, Xinxin Ding, David S. Riddick

Drug Metab Dispos. 2013 Oct; 41(10): 1782–1786. Published online 2013 Oct. doi: 10.1124/dmd.113.052993

PMCID:: PMC3781373

Abstract Article PDF–185K

Select item 37083579.

Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver

Mari Hashimoto, Kaoru Kobayashi, Mio Watanabe, Yasuhiro Kazuki, Shoko Takehara, Asumi Inaba, Shin-ichiro Nitta, Naoto Senda, Mitsuo Oshimura, Kan Chiba

J Lipid Res. 2013 Aug; 54(8): 2060–2068. doi: 10.1194/jlr.M033464

PMCID:: PMC3708357

Abstract Article PDF–623K

Select item 267280310.

Dynamic Patterns of Histone Methylation Are Associated with Ontogenic Expression of the Cyp3a Genes during Mouse Liver Maturation

Ye Li, Yue Cui, Steven N. Hart, Curtis D. Klaassen, Xiao-bo Zhong

Mol Pharmacol. 2009 May; 75(5): 1171–1179. Published online 2009 Feb 2. doi: 10.1124/mol.108.052993

PMCID:: PMC2672803

Abstract Article PDF–397K

Select item 239109111.

Midazolam metabolism in Cytochrome P450 3A knockout mice can be attributed to upregulated CYP2C enzymes

Robert A.B. van Waterschoot, Antonius E. van Herwaarden, Jurjen S. Lagas, Rolf W. Sparidans, Els Wagenaar, Cornelia M.M. van der Kruijssen, Joyce A. Goldstein, Darryl C. Zeldin, Jos H. Beijnen, Alfred H. Schinkel

Mol Pharmacol. Author manuscript; available in PMC 2008 May 21.

Published in final edited form as: Mol Pharmacol. 2008 Mar; 73(3): 1029–1036. Published online 2007 Dec 21. doi: 10.1124/mol.107.043869

PMCID:: PMC2391091

Abstract Article PDF–1.4M

Select item 578417612.

Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice

Line Zurkinden, Dmitri Sviridov, Bruno Vogt, Geneviève Escher

Biosci Rep. 2018 Feb 28; 38(1): BSR20171162. Prepublished online 2017 Nov 30. Published online 2018 Jan 25. doi: 10.1042/BSR20171162

PMCID:: PMC5784176

Abstract Article PDF–2.8M

Select item 339992013.

Opposing Regulation of Cytochrome P450 Expression by CAR and PXR in Hypothyroid Mice

Young Joo Park, Eun Kyung Lee, Yoon Kwang Lee, Do Joon Park, Hak Chul Jang, David D. Moore

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2012 Sep 1; 263(2): 131–137. Published online 2012 Apr 3. doi: 10.1016/j.taap.2012.03.017

PMCID:: PMC3399920

Abstract Article PDF–2.4M

Select item 429455614.

Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis

Craig D. Fisher, Jonathan P. Jackson, Andrew J. Lickteig, Lisa M. Augustine, Nathan J. Cherrington

Arch Toxicol. Author manuscript; available in PMC 2015 Jan 14.

Published in final edited form as: Arch Toxicol. 2008 Dec; 82(12): 959–964. Published online 2008 May 17. doi: 10.1007/s00204-008-0312-z

PMCID:: PMC4294556

Abstract Article PDF–379K

Select item 335553715.

The Steroid and Xenobiotic Receptor Negatively Regulates B-1 Cell Development in the Fetal Liver

Stephanie C. Casey, Bruce Blumberg

Mol Endocrinol. 2012 Jun; 26(6): 916–925. Published online 2012 Apr 11. doi: 10.1210/me.2011-1303

PMCID:: PMC3355537

Abstract Article

Select item 533836916.

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia

Shujuan Chen, Wenqi Lu, Mei-Fei Yueh, Eva Rettenmeier, Miao Liu, Miles Paszek, Johan Auwerx, Ruth T. Yu, Ronald M. Evans, Kepeng Wang, Michael Karin, Robert H. Tukey

Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): E1432–E1440. Published online 2017 Feb 6. doi: 10.1073/pnas.1700232114

Correction in:: Proc Natl Acad Sci U S A. 2017 May 16; 114(20): E4115.

PMCID:: PMC5338369

Abstract Article PDF–1.5M

Select item 338084717.

Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

Irina M. Bochkis, Jonathan Schug, Diana Z. Ye, Svitlana Kurinna, Sabrina A. Stratton, Michelle C. Barton, Klaus H. Kaestner

PLoS Genet. 2012 Jun; 8(6): e1002770. Published online 2012 Jun 21. doi: 10.1371/journal.pgen.1002770

PMCID:: PMC3380847

Abstract Article PDF–1.0M

Select item 389981218.

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment

Asha Seth, Jianming Ye, Nanjia Yu, Fanny Guez, David C. Bedford, Geoffrey A. Neale, Sabine Cordi, Paul K. Brindle, Frederic P. Lemaigre, Klaus H. Kaestner, Beatriz Sosa-Pineda

Development. 2014 Feb 1; 141(3): 538–547. doi: 10.1242/dev.099481

PMCID:: PMC3899812

Abstract Article

Select item 347860619.

Impact of lactobacilli on orally acquired listeriosis

Cristel Archambaud, Marie-Anne Nahori, Guillaume Soubigou, Christophe Bécavin, Laure Laval, Pierre Lechat, Tamara Smokvina, Philippe Langella, Marc Lecuit, Pascale Cossart

Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): 16684–16689. Published online 2012 Sep 24. doi: 10.1073/pnas.1212809109

PMCID:: PMC3478606

Abstract Article PDF–772K

Select item 645951020.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194