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Items: 1 to 20 of 45

1.
Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure
Matthew McMillin, Gabriel Frampton, Matthew Quinn, Samir Ashfaq, Mario de los Santos, III, Stephanie Grant, Sharon DeMorrow
Am J Pathol. 2016 Feb; 186(2): 312–323. doi: 10.1016/j.ajpath.2015.10.005
PMCID:
PMC4729266
AbstractArticlePDF–2.5M
2.
Disruption of Cholesterol 7α-Hydroxylase Gene in Mice: II. BILE ACID DEFICIENCY IS OVERCOME BY INDUCTION OF OXYSTEROL 7α-HYDROXYLASE
Margrit Schwarz, Erik G. Lund, Kenneth D. R. Setchell, Herbert J. Kayden, Joseph E. Zerwekh, Ingemar Björkhem, Joachim Herz, David W. Russell
J Biol Chem. Author manuscript; available in PMC 2015 Jun 2.
Published in final edited form as: J Biol Chem. 1996 Jul 26; 271(30): 18024–18031. doi: 10.1074/jbc.271.30.18024
PMCID:
PMC4451191
AbstractArticlePDF–1.4M
3.
Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice
Ryan D. Jones, Adam M. Lopez, Ernest Y. Tong, Kenneth S. Posey, Jen-Chieh Chuang, Joyce J. Repa, Stephen D. Turley
Steroids. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Steroids. 2015 Jan; 0: 87–95. Published online 2014 Nov 28. doi: 10.1016/j.steroids.2014.11.002
PMCID:
PMC4297738
AbstractArticlePDF–1.4M
4.
Overexpression of Cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis
Tiangang Li, Michelle Matozel, Shannon Boehme, Bo Kong, Lisa-Mari Nilsson, Grace Guo, Ewa Ellis, John Y. L. Chiang
Hepatology. Author manuscript; available in PMC 2012 Mar 1.
Published in final edited form as: Hepatology. 2011 Mar; 53(3): 996–1006. Published online 2011 Feb 11. doi: 10.1002/hep.24107
PMCID:
PMC3079544
AbstractArticlePDF–744K
5.
The 3'-untranslated region of the mouse cholesterol 7alpha-hydroxylase mRNA contains elements responsive to post-transcriptional regulation by bile acids.
L B Agellon, S K Cheema
Biochem J. 1997 Dec 1; 328(Pt 2): 393–399. doi: 10.1042/bj3280393
PMCID:
PMC1218933
SummaryPDF–553K
6.
Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway
Tetsuya Kouno, Xiao Liu, Huayi Zhao, Tatiana Kisseleva, Edward E. Cable, Bernd Schnabl
J Biol Chem. 2022 Jul; 298(7): 102056. Published online 2022 May 20. doi: 10.1016/j.jbc.2022.102056
PMCID:
PMC9214809
AbstractArticlePDF–898K
7.
Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice
Xiaoying Liu, Anne S. Henkel, Brian E. LeCuyer, Susan C. Hubchak, Matthew J. Schipma, Eric Zhang, Richard M. Green
J Lipid Res. 2017 Mar; 58(3): 504–511. Published online 2017 Feb 27. doi: 10.1194/jlr.M071266
PMCID:
PMC5335580
AbstractArticlePDF–1003K
8.
Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis
Hailiang Liu, Preeti Pathak, Shannon Boehme, John Y. L. Chiang
J Lipid Res. 2016 Oct; 57(10): 1831–1844. doi: 10.1194/jlr.M069807
PMCID:
PMC5036364
AbstractArticlePDF–2.2M
9.
Transient Gene Delivery for Functional Enrichment of Differentiating Embryonic Stem Cells
Eric J. Wallenstein, Jeffrey Barminko, Rene S. Schloss, Martin L. Yarmush
Biotechnol Bioeng. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: Biotechnol Bioeng. 2008 Dec 1; 101(5): 859–872. doi: 10.1002/bit.22027
PMCID:
PMC4487524
AbstractArticlePDF–1.7M
10.
Two uniquely arranged thyroid hormone response elements in the far upstream 5′ flanking region confer direct thyroid hormone regulation to the murine cholesterol 7α hydroxylase gene
Dong-Ju Shin, Michelina Plateroti, Jacques Samarut, Timothy F. Osborne
Nucleic Acids Res. 2006; 34(14): 3853–3861. Published online 2006 Aug 9. doi: 10.1093/nar/gkl506
PMCID:
PMC1557806
AbstractArticlePDF–340K
11.
Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine.
P J Voshol, M Schwarz, A Rigotti, M Krieger, A K Groen, F Kuipers
Biochem J. 2001 Jun 1; 356(Pt 2): 317–325. doi: 10.1042/0264-6021:3560317
PMCID:
PMC1221841
SummaryPDF–323K
12.
Cholesterol feeding of mice expressing cholesterol 7α-hydroxylase increases bile acid pool size despite decreased enzyme activity
Michaela Tiemann, Zhihua Han, Raymond Soccio, Jaya Bollineni, Sarah Shefer, Ephraim Sehayek, Jan L. Breslow
Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7): 1846–1851. Published online 2004 Feb 4. doi: 10.1073/pnas.0308426100
PMCID:
PMC357015
AbstractArticlePDF–431K
13.
Cholic acid mediates negative feedback regulation of bile acid synthesis in mice
Jia Li-Hawkins, Mats Gåfvels, Maria Olin, Erik G. Lund, Ulla Andersson, Gertrud Schuster, Ingemar Björkhem, David W. Russell, Gosta Eggertsen
J Clin Invest. 2002 Oct 15; 110(8): 1191–1200. doi: 10.1172/JCI16309
PMCID:
PMC150802
AbstractArticlePDF–1.2M
14.
Heat shock factor-1 knockout enhances cholesterol 7α-hydroxylase (CYP7A1) and multidrug transporter (MDR1) gene expressions to attenuate atherosclerosis
Karthikeyan Krishnamurthy, Shannon Glaser, Gianfranco D. Alpini, Arturo J. Cardounel, Zhenguo Liu, Govindasamy Ilangovan
Cardiovasc Res. 2016 Jul 1; 111(1): 74–83. Published online 2016 Apr 30. doi: 10.1093/cvr/cvw094
PMCID:
PMC4909164
AbstractArticlePDF–1.5M
15.
The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.
D D Patel, B L Knight, A K Soutar, G F Gibbons, D P Wade
Biochem J. 2000 Nov 1; 351(Pt 3): 747–753.
PMCID:
PMC1221415
SummaryPDF–155K
16.
Peroxisome Proliferator-activated Receptor γ Activation by Ligands and Dephosphorylation Induces Proprotein Convertase Subtilisin Kexin Type 9 and Low Density Lipoprotein Receptor Expression
Yajun Duan, Yuanli Chen, Wenquan Hu, Xiaoju Li, Xiaoxiao Yang, Xin Zhou, Zhinan Yin, Deling Kong, Zhi Yao, David P. Hajjar, Lin Liu, Qiang Liu, Jihong Han
J Biol Chem. 2012 Jul 6; 287(28): 23667–23677. Published online 2012 May 16. doi: 10.1074/jbc.M112.350181
PMCID:
PMC3390641
AbstractArticlePDF–2.0M
17.
Glucose and Insulin Induction of Bile Acid Synthesis: MECHANISMS AND IMPLICATION IN DIABETES AND OBESITY
Tiangang Li, Jessica M. Francl, Shannon Boehme, Adrian Ochoa, Youcai Zhang, Curtis D. Klaassen, Sandra K. Erickson, John Y. L. Chiang
J Biol Chem. 2012 Jan 13; 287(3): 1861–1873. Published online 2011 Dec 5. doi: 10.1074/jbc.M111.305789
PMCID:
PMC3265867
AbstractArticlePDF–2.6M
18.
Forkhead box transcription factor O1 inhibits cholesterol 7α-hydroxylase in human hepatocytes and in high fat diet-fed mice
Tiangang Li, Huiyan Ma, Young Joo Park, Yoon-Kwang Lee, Stephen Strom, David D. Moore, John Y. L. Chiang
Biochim Biophys Acta. Author manuscript; available in PMC 2010 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Oct; 1791(10): 991–996. Published online 2009 May 20. doi: 10.1016/j.bbalip.2009.05.004
PMCID:
PMC2743791
AbstractArticlePDF–372K
19.
Significance and Mechanism of CYP7a1 Gene Regulation during the Acute Phase of Liver Regeneration
Lisheng Zhang, Xiongfei Huang, Zhipeng Meng, Bingning Dong, Steven Shiah, David D. Moore, Wendong Huang
Mol Endocrinol. 2009 Feb; 23(2): 137–145. Published online 2008 Dec 4. doi: 10.1210/me.2008-0198
PMCID:
PMC2725763
AbstractArticle
20.
Decreased Expression of Cholesterol 7α-Hydroxylase and Altered Bile Acid Metabolism in Apobec-1−/− Mice Lead to Increased Gallstone Susceptibility
Yan Xie, Valerie Blanc, Thomas A. Kerr, Susan Kennedy, Jianyang Luo, Elizabeth P. Newberry, Nicholas O. Davidson
J Biol Chem. 2009 Jun 19; 284(25): 16860–16871. Published online 2009 Apr 22. doi: 10.1074/jbc.M109.010173
PMCID:
PMC2719322
AbstractArticlePDF–651K

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