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Items: 1 to 20 of 73

1.
Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway
Bin Yang, Yunjie Zhao, Wu Luo, Weiwei Zhu, Leiming Jin, Minxiu Wang, Lin Ye, Yi Wang, Guang Liang
Cell Death Dis. 2023 Jul; 14(7): 419. Published online 2023 Jul 13. doi: 10.1038/s41419-023-05960-4
PMCID:
PMC10345119
AbstractArticlePDF–7.0M
2.
Doublecortin-like kinase 1 (DCLK1) Facilitates Dendritic Spine Growth of Pyramidal Neurons in Mouse Prefrontal Cortex
Kelsey E. Murphy, Erin Y. Zhang, Elliott V. Wyatt, Justin E. Sperringer, Bryce W. Duncan, Patricia F. Maness
Neuroscience. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Neuroscience. 2023 Jan 1; 508: 98–109. Published online 2022 Sep 3. doi: 10.1016/j.neuroscience.2022.08.020
PMCID:
PMC10317307
AbstractArticlePDF–1.5M
3.
Doublecortin-like kinase 1 activates NF-κB to induce inflammatory responses by binding directly to IKKβ
Wu Luo, Yiyi Jin, Yuchen Jiang, Libin Yang, Haowen Xu, Di Wu, Yanmei Zhang, Lina Yin, Zia Ali Khan, Guang Liang, Yi Wang
Cell Death Differ. 2023 May; 30(5): 1184–1197. Published online 2023 Mar 13. doi: 10.1038/s41418-023-01147-8
PMCID:
PMC10154386
AbstractArticlePDF–6.3M
4.
Doublecortin‐like expressing astrocytes of the suprachiasmatic nucleus are implicated in the biosynthesis of vasopressin and influences circadian rhythms
Claudia Coomans, Dirk‐Jan Saaltink, Tom Deboer, Mayke Tersteeg, Suzanne Lanooij, Anne Fleur Schneider, Aat Mulder, Jan van Minnen, Carolina Jost, Abraham J. Koster, Erno Vreugdenhil
Glia. 2021 Nov; 69(11): 2752–2766. Published online 2021 Aug 3. doi: 10.1002/glia.24069
PMCID:
PMC9291169
AbstractArticlePDF–18M
5.
Doublecortin-Like Is Implicated in Adult Hippocampal Neurogenesis and in Motivational Aspects to Escape from an Aversive Environment in Male Mice
Dirk-Jan Saaltink, Erik W. van Zwet, Erno Vreugdenhil
eNeuro. 2020 Sep-Oct; 7(5): ENEURO.0324-19.2020. Prepublished online 2020 Sep 29. Published online 2020 Oct 14. doi: 10.1523/ENEURO.0324-19.2020
PMCID:
PMC7568604
AbstractArticlePDF–1.7M
6.
Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis
Jun Yi, Kirk Bergstrom, Jianxin Fu, Xindi Shan, J. Michael McDaniel, Samuel McGee, Dongfeng Qu, Courtney W. Houchen, Xiaowei Liu, Lijun Xia
Cell Death Differ. 2019 Sep; 26(9): 1656–1669. Published online 2018 Nov 26. doi: 10.1038/s41418-018-0237-x
PMCID:
PMC6748088
AbstractArticlePDF–4.3M
7.
The Doublecortin-Expressing Population in the Developing and Adult Brain Contains Multipotential Precursors in Addition to Neuronal-Lineage Cells
Tara L. Walker, Takahiro Yasuda, David J. Adams, Perry F. Bartlett
J Neurosci. 2007 Apr 4; 27(14): 3734–3742. doi: 10.1523/JNEUROSCI.5060-06.2007
PMCID:
PMC6672401
AbstractArticlePDF–479K
8.
Functional implication of Dclk1 and Dclk1-expressing cells in cancer
C. Benedikt Westphalen, Michael Quante, Timothy C. Wang
Small GTPases. 2017; 8(3): 164–171. Published online 2016 Jul 26. doi: 10.1080/21541248.2016.1208792
PMCID:
PMC5584739
AbstractArticlePDF–461K
9.
Dclk1 Deletion in Tuft Cells Results in Impaired Epithelial Repair After Radiation Injury
Randal May, Dongfeng Qu, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Stanley A. Lightfoot, Linheng Li, Sripathi M. Sureban, Courtney W. Houchen
Stem Cells. Author manuscript; available in PMC 2015 Oct 13.
Published in final edited form as: Stem Cells. 2014 Mar; 32(3): 822–827. doi: 10.1002/stem.1566
PMCID:
PMC4603545
AbstractArticlePDF–1.2M
10.
Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis
Dongfeng Qu, Nathaniel Weygant, Randal May, Parthasarathy Chandrakesan, Mohammad Madhoun, Naushad Ali, Sripathi M. Sureban, Guangyu An, Michael J. Schlosser, Courtney W. Houchen
PLoS One. 2015; 10(8): e0134212. Published online 2015 Aug 18. doi: 10.1371/journal.pone.0134212
PMCID:
PMC4540568
AbstractArticlePDF–2.9M
11.
Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury
Dongfeng Qu, Randal May, Sripathi M. Sureban, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Linheng Li, Terrence Barrett, Courtney W. Houchen
Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1; 306(5): G404–G411. Published online 2013 Dec 25. doi: 10.1152/ajpgi.00088.2013
PMCID:
PMC3949020
AbstractArticle
12.
Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome
Xiao-Yue Chen, Ching Kao, Syue-Wei Peng, Jer-Hwa Chang, Yueh-Lun Lee, Vincent Laiman, Kian Fan Chung, Pankaj K. Bhavsar, Didik Setyo Heriyanto, Kai-Jen Chuang, Hsiao-Chi Chuang
Mol Med. 2023; 29: 159. Published online 2023 Nov 23. doi: 10.1186/s10020-023-00760-0
PMCID:
PMC10668445
AbstractArticlePDF–4.6M
13.
Macrophage DCLK1 promotes atherosclerosis via binding to IKKβ and inducing inflammatory responses
Zhuqi Huang, Sirui Shen, Xue Han, Weixin Li, Wu Luo, Liming Lin, Mingjiang Xu, Yi Wang, Weijian Huang, Gaojun Wu, Guang Liang
EMBO Mol Med. 2023 May; 15(5): e17198. Published online 2023 Mar 10. doi: 10.15252/emmm.202217198
PMCID:
PMC10165355
AbstractArticlePDF–3.6M
14.
Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
Yang Ge, Nathaniel Weygant, Dongfeng Qu, Randal May, William L. Berry, Jiannan Yao, Parthasarathy Chandrakesan, Wei Zheng, Lichao Zhao, Karena L. Zhao, Michael Drake, Kenneth J. Vega, Michael S. Bronze, James J. Tomasek, Guangyu An, Courtney W. Houchen
Int J Cancer. Author manuscript; available in PMC 2021 Aug 25.
Published in final edited form as: Int J Cancer. 2018 Sep 1; 143(5): 1162–1175. Published online 2018 Apr 16. doi: 10.1002/ijc.31400
PMCID:
PMC8386112
AbstractArticlePDF–2.7M
15.
Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity
Gabriel E. Vázquez-Vélez, Kristyn A. Gonzales, Jean-Pierre Revelli, Carolyn J. Adamski, Fatemeh Alavi Naini, Aleksandar Bajić, Evelyn Craigen, Ronald Richman, Sabrina M. Heman-Ackah, Matthew J.A. Wood, Maxime W.C. Rousseaux, Huda Y. Zoghbi
J Neurosci. 2020 Jan 8; 40(2): 459–477. doi: 10.1523/JNEUROSCI.1076-19.2019
PMCID:
PMC6948939
AbstractArticlePDF–9.4M
16.
The Microtubule-Associated Protein Doublecortin-Like Regulates the Transport of the Glucocorticoid Receptor in Neuronal Progenitor Cells
Carlos P. Fitzsimons, Suaad Ahmed, Christiaan F. W. Wittevrongel, Theo G. Schouten, Thomas F. Dijkmans, Wim J. J. M. Scheenen, Marcel J. M. Schaaf, E. Ronald de Kloet, Erno Vreugdenhil
Mol Endocrinol. February 1, 2008; 22(2): 248–262. doi: 10.1210/me.2007-0233
PMCID:
PMC5419639
AbstractArticle
17.
Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury
Parthasarathy Chandrakesan, Randal May, Nathaniel Weygant, Dongfeng Qu, William L. Berry, Sripathi M. Sureban, Naushad Ali, Chinthalapally Rao, Mark Huycke, Michael S. Bronze, Courtney W. Houchen
Sci Rep. 2016; 6: 37667. Published online 2016 Nov 23. doi: 10.1038/srep37667
PMCID:
PMC5120335
AbstractArticlePDF–3.0M
18.
Dclk1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition
Parthasarathy Chandrakesan, Nathaniel Weygant, Randal May, Dongfeng Qu, Harisha R. Chinthalapally, Sripathi M. Sureban, Naushad Ali, Stan A. Lightfoot, Shahid Umar, Courtney W. Houchen
Oncotarget. 2014 Oct; 5(19): 9269–9280. Published online 2014 Sep 2. doi: 10.18632/oncotarget.2393
PMCID:
PMC4253433
AbstractArticlePDF–3.5M
19.
DCLK1 Marks a Morphologically Distinct Subpopulation of Cells with Stem Cell Properties in Pre-invasive Pancreatic Cancer
Jennifer M. Bailey, Janivette Alsina, Zeshaan A. Rasheed, Florencia M. McAllister, Ya-Yuan Fu, Ruben Plentz, Hao Zhang, Pankaj J. Pasricha, Nabeel Bardeesy, William Matsui, Anirban Maitra, Steven D. Leach
Gastroenterology. Author manuscript; available in PMC 2015 Jan 1.
Published in final edited form as: Gastroenterology. 2014 Jan; 146(1): 245–256. Published online 2013 Oct 2. doi: 10.1053/j.gastro.2013.09.050
PMCID:
PMC3910427
AbstractArticlePDF–3.9M
20.
DCLK1 Regulates Pluripotency and Angiogenic Factors via microRNA-Dependent Mechanisms in Pancreatic Cancer
Sripathi M. Sureban, Randal May, Dongfeng Qu, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Stan A. Lightfoot, Panayotis Pantazis, Chinthalapally V. Rao, Russell G. Postier, Courtney W. Houchen
PLoS One. 2013; 8(9): e73940. Published online 2013 Sep 9. doi: 10.1371/journal.pone.0073940
PMCID:
PMC3767662
AbstractArticlePDF–3.1M

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