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Select item 101758291.

The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer

Lincoln N. Strickland, Erika Y. Faraoni, Wei Ruan, Xiaoyi Yuan, Holger K. Eltzschig, Jennifer M. Bailey-Lundberg

Front Immunol. 2023; 14: 1163585. Published online 2023 Apr 28. doi: 10.3389/fimmu.2023.1163585

PMCID:: PMC10175829

Abstract Article PDF–11M

Select item 91007692.

Adenosine Receptor A2B Negatively Regulates Cell Migration in Ovarian Carcinoma Cells

Anaí del Rocío Campos-Contreras, Adriana González-Gallardo, Mauricio Díaz-Muñoz, Francisco G. Vázquez-Cuevas

Int J Mol Sci. 2022 May; 23(9): 4585. Published online 2022 Apr 21. doi: 10.3390/ijms23094585

PMCID:: PMC9100769

Abstract Article PDF–7.8M

Select item 75298533.

Tumor-derived exosomes promote angiogenesis via adenosine A_2B receptor signalling

Nils Ludwig, Saigopalakrishna S. Yerneni, Juliana H. Azambuja, Delbert G. Gillespie, Elizabeth V. Menshikova, Edwin K. Jackson, Theresa. L. Whiteside

Angiogenesis. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Angiogenesis. 2020 Nov; 23(4): 599–610. Published online 2020 May 18. doi: 10.1007/s10456-020-09728-8

PMCID:: PMC7529853

Abstract Article PDF–781K

Select item 70315294.

Cysteine redox state regulates human β2-adrenergic receptor binding and function

Kalyn M. Rambacher, Nader H. Moniri

Sci Rep. 2020; 10: 2934. Published online 2020 Feb 19. doi: 10.1038/s41598-020-59983-4

PMCID:: PMC7031529

Abstract Article PDF–3.3M

Select item 66286205.

The Adenosine A_2B Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments

Helen J. Knowles

Cells. 2019 Jun; 8(6): 624. Published online 2019 Jun 21. doi: 10.3390/cells8060624

PMCID:: PMC6628620

Abstract Article PDF–1.9M

Select item 61871576.

Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment

Jie Lan, Haiquan Lu, Debangshu Samanta, Shaima Salman, You Lu, Gregg L. Semenza

Proc Natl Acad Sci U S A. 2018 Oct 9; 115(41): E9640–E9648. Published online 2018 Sep 21. doi: 10.1073/pnas.1809695115

Correction in:: Proc Natl Acad Sci U S A. 2022 Sep 20; 119(38): e2210925119.

PMCID:: PMC6187157

Abstract Article PDF–1.9M

Select item 53766387.

Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals

Simona Daniele, Letizia Natali, Chiara Giacomelli, Pietro Campiglia, Ettore Novellino, Claudia Martini, Maria Letizia Trincavelli

Mol Cell Biol. 2017 Apr 15; 37(8): e00442-16. Prepublished online 2017 Jan 30. Published online 2017 Mar 31. doi: 10.1128/MCB.00442-16

PMCID:: PMC5376638

Abstract Article PDF–2.1M

Select item 49469488.

Purinergic A2b Receptor Activation by Extracellular Cues Affects Positioning of the Centrosome and Nucleus and Causes Reduced Cell Migration

Young Ou, Gordon Chan, Jeremy Zuo, Jerome B. Rattner, Frans A. van der Hoorn

J Biol Chem. 2016 Jul 15; 291(29): 15388–15403. Published online 2016 May 13. doi: 10.1074/jbc.M116.721241

PMCID:: PMC4946948

Abstract Article PDF–3.0M

Select item 45202749.

Adenosine A2b receptor promotes progression of human oral cancer

Hiroki Kasama, Yosuke Sakamoto, Atsushi Kasamatsu, Atsushi Okamoto, Tomoyoshi Koyama, Yasuyuki Minakawa, Katsunori Ogawara, Hidetaka Yokoe, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa

BMC Cancer. 2015; 15: 563. Published online 2015 Jul 31. doi: 10.1186/s12885-015-1577-2

PMCID:: PMC4520274

Abstract Article PDF–2.9M

Select item 415244810.

Role of adenosine A_2B receptor signaling in contribution of cardiac mesenchymal stem-like cells to myocardial scar formation

Sergey Ryzhov, Bong Hwan Sung, Qinkun Zhang, Alissa Weaver, Richard J. Gumina, Italo Biaggioni, Igor Feoktistov

Purinergic Signal. 2014 Sep; 10(3): 477–486. Published online 2014 Mar 1. doi: 10.1007/s11302-014-9410-y

PMCID:: PMC4152448

Abstract Article PDF–1.0M

Select item 402441411.

Potential Role of A_2B Adenosine Receptors on Proliferation/Migration of Fetal Endothelium Derived from Preeclamptic Pregnancies

Jesenia Acurio, Felipe Troncoso, Patricio Bertoglia, Carlos Salomon, Claudio Aguayo, Luis Sobrevia, Carlos Escudero

Biomed Res Int. 2014; 2014: 274507. Published online 2014 Apr 28. doi: 10.1155/2014/274507

PMCID:: PMC4024414

Abstract Article PDF–1.0M

Select item 278822812.

The Danger Signal Adenosine Induces Persistence of Chlamydial Infection through Stimulation of A2b Receptors

Matthew A. Pettengill, Verissa W. Lam, David M. Ojcius

PLoS One. 2009; 4(12): e8299. Published online 2009 Dec 14. doi: 10.1371/journal.pone.0008299

PMCID:: PMC2788228

Abstract Article PDF–420K

Select item 254245513.

A_2B Adenosine Receptors Regulate the Mucus Clearance Component of the Lung's Innate Defense System

Brett M. Rollins, Mellisa Burn, Ray D. Coakley, Lucy A. Chambers, Andrew J. Hirsh, Mark T. Clunes, Michael I. Lethem, Scott H. Donaldson, Robert Tarran

Am J Respir Cell Mol Biol. 2008 Aug; 39(2): 190–197. Published online 2008 Mar 26. doi: 10.1165/rcmb.2007-0450OC

PMCID:: PMC2542455

Abstract Article PDF–614K

Select item 219418914.

Coordinated Adenine Nucleotide Phosphohydrolysis and Nucleoside Signaling in Posthypoxic Endothelium: Role of Ectonucleotidases and Adenosine A_2B Receptors

Holger K. Eltzschig, Juan C. Ibla, Glenn T. Furuta, Martin O. Leonard, Kenneth A. Jacobson, Keiichi Enjyoji, Simon C. Robson, Sean P. Colgan

J Exp Med. 2003 Sep 1; 198(5): 783–796. doi: 10.1084/jem.20030891

PMCID:: PMC2194189

Abstract Article PDF–544K

Select item 743751615.

Adenosine/A2B receptor signaling ameliorates the effects of ageing and counteracts obesity

Thorsten Gnad, Gemma Navarro, Minna Lahesmaa, Laia Reverte-Salisa, Francesca Copperi, Arnau Cordomi, Jennifer Naumann, Aileen Hochhäuser, Saskia Haufs-Brusberg, Daniela Wenzel, Frank Suhr, Naja Zenius Jespersen, Camilla Scheele, Volodymyr Tsvilovskyy, Christian Brinkmann, Joern Rittweger, Christian Dani, Mathias Kranz, Winnie Deuther-Conrad, Holger K. Eltzschig, Tarja Niemi, Markku Taittonen, Peter Brust, Pirjo Nuutila, Leonardo Pardo, Bernd K. Fleischmann, Matthias Blüher, Rafael Franco, Wilhelm Bloch, Kirsi A. Virtanen, Alexander Pfeifer

Cell Metab. Author manuscript; available in PMC 2021 Jul 7.

Published in final edited form as: Cell Metab. 2020 Jul 7; 32(1): 56–70.e7. Published online 2020 Jun 25. doi: 10.1016/j.cmet.2020.06.006

PMCID:: PMC7437516

Abstract Article PDF–2.2M

Select item 629304916.

Adenosinergic signaling inhibits oxalate transport by human intestinal Caco2-BBE cells through the A_2B adenosine receptor

Daniel Jung, Altayeb Alshaikh, Sireesha Ratakonda, Mohamed Bashir, Ruhul Amin, Sohee Jeon, Jan Stevens, Sapna Sharma, Wahaj Ahmed, Mark Musch, Hatim Hassan

Am J Physiol Cell Physiol. 2018 Nov 1; 315(5): C687–C698. Published online 2018 Jul 18. doi: 10.1152/ajpcell.00024.2017

PMCID:: PMC6293049

Abstract Article

Select item 434686217.

The Association of ADORA2A and ADORA2B Polymorphisms with the Risk and Severity of Chronic Heart Failure: A Case-Control Study of a Northern Chinese Population

Ya-Jing Zhai, Ping Liu, Hai-Rong He, Xiao-Wei Zheng, Yan Wang, Qian-Ting Yang, Ya-Lin Dong, Jun Lu

Int J Mol Sci. 2015 Feb; 16(2): 2732–2746. Published online 2015 Jan 26. doi: 10.3390/ijms16022732

PMCID:: PMC4346862

Abstract Article PDF–702K

Select item 427837618.

An Adenosine-Mediated Signaling Pathway Suppresses Prenylation of the GTPase Rap1B and Promotes Cell Scattering

Elizabeth Ntantie, Patrick Gonyo, Ellen L. Lorimer, Andrew D. Hauser, Nathan Schuld, Donna McAllister, Balaraman Kalyanaraman, Michael B. Dwinell, John A. Auchampach, Carol L. Williams

Sci Signal. Author manuscript; available in PMC 2014 Dec 29.

Published in final edited form as: Sci Signal. 2013 May 28; 6(277): ra39. Published online 2013 May 28. doi: 10.1126/scisignal.2003374

PMCID:: PMC4278376

Abstract Article PDF–781K

Select item 426074519.

Modulation of A₁ and A_2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy

S Daniele, E Zappelli, L Natali, C Martini, M L Trincavelli

Cell Death Dis. 2014 Nov; 5(11): e1539. Published online 2014 Nov 27. doi: 10.1038/cddis.2014.487

PMCID:: PMC4260745

Abstract Article PDF–4.0M

Select item 415245720.

A yeast screening method to decipher the interaction between the adenosine A_2B receptor and the C-terminus of different G protein α-subunits

Rongfang Liu, Nick J. A. Groenewoud, Miriam C. Peeters, Eelke B. Lenselink, Ad P. IJzerman

Purinergic Signal. 2014 Sep; 10(3): 441–453. Published online 2014 Jan 26. doi: 10.1007/s11302-014-9407-6

PMCID:: PMC4152457

Abstract Article PDF–1.4M

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