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Select item 21937431.

Polycomb Group Gene rae28 Is Required for Sustaining Activity of Hematopoietic Stem Cells

Hideaki Ohta, Akihisa Sawada, Ji Yoo Kim, Sadao Tokimasa, Seiji Nishiguchi, R. Keith Humphries, Junichi Hara, Yoshihiro Takihara

J Exp Med. 2002 Mar 18; 195(6): 759–770. doi: 10.1084/jem.20011911

PMCID:: PMC2193743

Abstract Article PDF–271K

Select item 81218812.

PHC1 maintains pluripotency by organizing genome-wide chromatin interactions of the Nanog locus

Li Chen, Qiaoqiao Tong, Xiaowen Chen, Penglei Jiang, Hua Yu, Qianbing Zhao, Lingang Sun, Chao Liu, Bin Gu, Yuping Zheng, Lijiang Fei, Xiao Jiang, Wenjuan Li, Giacomo Volpe, Mazid MD. Abdul, Guoji Guo, Jin Zhang, Pengxu Qian, Qiming Sun, Dante Neculai, Miguel A. Esteban, Chen Li, Feiqiu Wen, Junfeng Ji

Nat Commun. 2021; 12: 2829. Published online 2021 May 14. doi: 10.1038/s41467-021-22871-0

PMCID:: PMC8121881

Abstract Article PDF–2.9M

Select item 2638193.

Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants

Wim de Graaff, Daihachiro Tomotsune, Tony Oosterveen, Yoshihiro Takihara, Haruhiko Koseki, Jacqueline Deschamps

Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23): 13362–13367. Published online 2003 Oct 31. doi: 10.1073/pnas.2237046100

PMCID:: PMC263819

Abstract Article PDF–614K

Select item 30031014.

Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential

Yoshinori Ohno, Shin'ichiro Yasunaga, Motoaki Ohtsubo, Sayaka Mori, Miyuki Tsumura, Satoshi Okada, Tomohiko Ohta, Kiyoshi Ohtani, Masao Kobayashi, Yoshihiro Takihara

Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50): 21529–21534. Published online 2010 Nov 22. doi: 10.1073/pnas.1011054107

PMCID:: PMC3003101

Abstract Article PDF–1.0M

Select item 105229995.

Acquisition of neural fate by combination of BMP blockade and chromatin modification

Agnes Lee Chen Ong, Toshiya Kokaji, Arisa Kishi, Yoshihiro Takihara, Takuma Shinozuka, Ren Shimamoto, Ayako Isotani, Manabu Shirai, Noriaki Sasai

iScience. 2023 Oct 20; 26(10): 107887. Published online 2023 Sep 9. doi: 10.1016/j.isci.2023.107887

Correction in:: iScience. 2023 Nov 17; 26(11): 108257.

PMCID:: PMC10522999

Abstract Article PDF–6.7M

Select item 35713396.

Scmh1 Has E3 Ubiquitin Ligase Activity for Geminin and Histone H2A and Regulates Geminin Stability Directly or Indirectly via Transcriptional Repression of Hoxa9 and Hoxb4

Shin'ichiro Yasunaga, Motoaki Ohtsubo, Yoshinori Ohno, Keita Saeki, Toshiaki Kurogi, Miki Tanaka-Okamoto, Hiroyoshi Ishizaki, Manabu Shirai, Keichiro Mihara, Hugh W. Brock, Jun Miyoshi, Yoshihiro Takihara

Mol Cell Biol. 2013 Feb; 33(4): 644–660. doi: 10.1128/MCB.00974-12

PMCID:: PMC3571339

Abstract Article PDF–6.1M

Select item 26885287.

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells

Jessica Schwermann, Chozhavendan Rathinam, Maria Schubert, Stefanie Schumacher, Fatih Noyan, Haruhiko Koseki, Alexey Kotlyarov, Christoph Klein, Matthias Gaestel

EMBO J. 2009 May 20; 28(10): 1392–1406. Published online 2009 Apr 16. doi: 10.1038/emboj.2009.100

PMCID:: PMC2688528

Abstract Article PDF–2.0M

Select item 32819928.

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

Lígia Tavares, Emilia Dimitrova, David Oxley, Judith Webster, Raymond Poot, Jeroen Demmers, Karel Bezstarosti, Stephen Taylor, Hiroki Ura, Hiroshi Koide, Anton Wutz, Miguel Vidal, Sarah Elderkin, Neil Brockdorff

Cell. 2012 Feb 17; 148(4): 664–678. doi: 10.1016/j.cell.2011.12.029

Correction in:: Cell. 2012 Jun 22; 149(7): 1647–1648.

PMCID:: PMC3281992

Abstract Article PDF–1.9M

Select item 11903569.

Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes

Kyo-ichi Isono, Yu-ichi Fujimura, Jun Shinga, Makoto Yamaki, Jiyang O-Wang, Yoshihiro Takihara, Yasuaki Murahashi, Yuki Takada, Yoko Mizutani-Koseki, Haruhiko Koseki

Mol Cell Biol. 2005 Aug; 25(15): 6694–6706. doi: 10.1128/MCB.25.15.6694-6706.2005

Correction in:: Mol Cell Biol. 2014 Jul; 34(14): 2771.

PMCID:: PMC1190356

Abstract Article PDF–1.2M

Select item 249251410.

Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity

Motoaki Ohtsubo, Shin'ichiro Yasunaga, Yoshinori Ohno, Miyuki Tsumura, Satoshi Okada, Nobutsune Ishikawa, Kenichiro Shirao, Akira Kikuchi, Hideo Nishitani, Masao Kobayashi, Yoshihiro Takihara

Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30): 10396–10401. Published online 2008 Jul 23. doi: 10.1073/pnas.0800672105

PMCID:: PMC2492514

Abstract Article PDF–547K

Select item 15104411.

The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis

Manabu Shirai, Tomoaki Osugi, Hideyuki Koga, Yoshikazu Kaji, Eiki Takimoto, Issei Komuro, Junichi Hara, Takeshi Miwa, Keiko Yamauchi-Takihara, Yoshihiro Takihara

J Clin Invest. 2002 Jul 15; 110(2): 177–184. doi: 10.1172/JCI14839

PMCID:: PMC151044

Abstract Article PDF–3.5M

Select item 55157412.

Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1

Kyoichi Isono, Yoko Mizutani-Koseki, Toshihisa Komori, Marion S. Schmidt-Zachmann, Haruhiko Koseki

Genes Dev. 2005 Mar 1; 19(5): 536–541. doi: 10.1101/gad.1284605

PMCID:: PMC551574

Abstract Article PDF–592K

Select item 13401613.

The Core of the Polycomb Repressive Complex Is Compositionally and Functionally Conserved in Flies and Humans

Stuart S. Levine, Alona Weiss, Hediye Erdjument-Bromage, Zhaohui Shao, Paul Tempst, Robert E. Kingston

Mol Cell Biol. 2002 Sep; 22(17): 6070–6078. doi: 10.1128/MCB.22.17.6070-6078.2002

PMCID:: PMC134016

Abstract Article PDF–341K

Select item 1033036214.

Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/RBM38 axis

Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon

Circulation. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Circulation. 2023 Jun 13; 147(24): 1823–1842. Published online 2023 May 9. doi: 10.1161/CIRCULATIONAHA.122.061131

PMCID:: PMC10330362

Abstract Article PDF–1.6M

Select item 327871715.

Direct Recruitment of Polycomb Repressive Complex 1 (PRC1) to Chromatin by Core Binding Transcription Factors

Ming Yu, Tali Mazor, Hui Huang, Hsuan-Ting Huang, Katie L. Kathrein, Andrew J. Woo, Candace R. Chouinard, Adam Labadorf, Thomas E. Akie, Tyler B. Moran, Huafeng Xie, Sima Zacharek, Ichiro Taniuchi, Robert G. Roeder, Carla F. Kim, Leonard I. Zon, Ernest Fraenkel, Alan B. Cantor

Mol Cell. Author manuscript; available in PMC 2013 Feb 10.

Published in final edited form as: Mol Cell. 2012 Feb 10; 45(3): 330–343. doi: 10.1016/j.molcel.2011.11.032

PMCID:: PMC3278717

Abstract Article PDF–2.6M

Select item 332215616.

PRC1 and PRC2 Are Not Required for Targeting of H2A.Z to Developmental Genes in Embryonic Stem Cells

Robert S. Illingworth, Catherine H. Botting, Graeme R. Grimes, Wendy A. Bickmore, Ragnhild Eskeland

PLoS One. 2012; 7(4): e34848. Published online 2012 Apr 9. doi: 10.1371/journal.pone.0034848

PMCID:: PMC3322156

Abstract Article PDF–1.5M

Select item 374619817.

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

Alessia Gagliardi, Nicholas P Mullin, Zi Ying Tan, Douglas Colby, Anastasia I Kousa, Florian Halbritter, Jason T Weiss, Anastasia Felker, Karel Bezstarosti, Rebecca Favaro, Jeroen Demmers, Silvia K Nicolis, Simon R Tomlinson, Raymond A Poot, Ian Chambers

EMBO J. 2013 Aug 14; 32(16): 2231–2247. Published online 2013 Jul 26. doi: 10.1038/emboj.2013.161

PMCID:: PMC3746198

Abstract Article PDF–2.9M

Select item 309339518.

RAD21 Cooperates with Pluripotency Transcription Factors in the Maintenance of Embryonic Stem Cell Identity

Anja Nitzsche, Maciej Paszkowski-Rogacz, Filomena Matarese, Eva M. Janssen-Megens, Nina C. Hubner, Herbert Schulz, Ingrid de Vries, Li Ding, Norbert Huebner, Matthias Mann, Hendrik G. Stunnenberg, Frank Buchholz

PLoS One. 2011; 6(5): e19470. Published online 2011 May 12. doi: 10.1371/journal.pone.0019470