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Select item 111584671.

Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model

Yuan Wen, Chun‐Ting Wang, Tian‐Tai Ma, Zhi‐Yong Li, Li‐Na Zhou, Bo Mu, Fei Leng, Hua‐Shan Shi, Ya‐Ou Li, Yu‐Quan Wei

Cancer Sci. 2010 Nov; 101(11): 2325–2332. Published online 2010 Jul 30. doi: 10.1111/j.1349-7006.2010.01695.x

PMCID:: PMC11158467

Abstract Article PDF–868K

Select item 79352872.

Genetic ablation of fibroblast activation protein alpha attenuates left ventricular dilation after myocardial infarction

Daniel B. Hoffmann, Daniela Fraccarollo, Paolo Galuppo, Stefan Frantz, Johann Bauersachs, Jochen Tillmanns

PLoS One. 2021; 16(3): e0248196. Published online 2021 Mar 5. doi: 10.1371/journal.pone.0248196

PMCID:: PMC7935287

Abstract Article PDF–1.5M

Select item 68815463.

Fibroblast activation protein restrains adipogenic differentiation and regulates matrix-mediated mTOR signaling

Rachel Blomberg, Daniel P. Beiting, Martin Wabitsch, Ellen Puré

Matrix Biol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Matrix Biol. 2019 Oct; 83: 60–76. Published online 2019 Jul 17. doi: 10.1016/j.matbio.2019.07.007

PMCID:: PMC6881546

Abstract Article PDF–3.0M

Select item 67809954.

Embryonic FAP⁺ lymphoid tissue organizer cells generate the reticular network of adult lymph nodes

Alice E. Denton, Edward J. Carr, Lukasz P. Magiera, Andrew J.B. Watts, Douglas T. Fearon

J Exp Med. 2019 Oct 7; 216(10): 2242–2252. Published online 2019 Jul 19. doi: 10.1084/jem.20181705

PMCID:: PMC6780995

Abstract Article PDF–4.3M

Select item 63649205.

Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma

Andrew J. Gunderson, Tomoko Yamazaki, Kayla McCarty, Michaela Phillips, Alejandro Alice, Shelly Bambina, Lauren Zebertavage, David Friedman, Benjamin Cottam, Pippa Newell, Michael J. Gough, Marka R. Crittenden, Pieter Van der Veken, Kristina H. Young

PLoS One. 2019; 14(2): e0211117. Published online 2019 Feb 6. doi: 10.1371/journal.pone.0211117

PMCID:: PMC6364920

Abstract Article PDF–4.0M

Select item 63174736.

Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics

Hui Emma Zhang, Elizabeth J. Hamson, Maria Magdalena Koczorowska, Stefan Tholen, Sumaiya Chowdhury, Charles G. Bailey, Angelina J. Lay, Stephen M. Twigg, Quintin Lee, Ben Roediger, Martin L. Biniossek, Matthew B. O'Rourke, Geoffrey W. McCaughan, Fiona M. Keane, Oliver Schilling, Mark D. Gorrell

Mol Cell Proteomics. 2019 Jan; 18(1): 65–85. Published online 2018 Sep 26. doi: 10.1074/mcp.RA118.001046

PMCID:: PMC6317473

Abstract Article PDF–3.6M

Select item 56249137.

Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP)

Travis W. Bainbridge, Diana Ronai Dunshee, Noelyn M. Kljavin, Nicholas J. Skelton, Junichiro Sonoda, James A. Ernst

Sci Rep. 2017; 7: 12524. Published online 2017 Oct 2. doi: 10.1038/s41598-017-12900-8

PMCID:: PMC5624913

Abstract Article PDF–1.8M

Select item 48250118.

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

Ming-Hui Fan, Qiang Zhu, Hui-Hua Li, Hyun-Jeong Ra, Sonali Majumdar, Dexter L. Gulick, Jacob A. Jerome, Daniel H. Madsen, Melpo Christofidou-Solomidou, David W. Speicher, William W. Bachovchin, Carol Feghali-Bostwick, Ellen Puré

J Biol Chem. 2016 Apr 8; 291(15): 8070–8089. Published online 2015 Dec 9. doi: 10.1074/jbc.M115.701433

PMCID:: PMC4825011

Abstract Article PDF–5.4M

Select item 36747089.

Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia

Edward W. Roberts, Andrew Deonarine, James O. Jones, Alice E. Denton, Christine Feig, Scott K. Lyons, Marion Espeli, Matthew Kraman, Brendan McKenna, Richard J.B. Wells, Qi Zhao, Otavia L. Caballero, Rachel Larder, Anthony P. Coll, Stephen O’Rahilly, Kevin M. Brindle, Sarah A. Teichmann, David A. Tuveson, Douglas T. Fearon

J Exp Med. 2013 Jun 3; 210(6): 1137–1151. doi: 10.1084/jem.20122344

PMCID:: PMC3674708

Abstract Article PDF–3.6M

Select item 1074352510.

FAP expression in adipose tissue macrophages promotes obesity and metabolic inflammation

Yunyun Wu, Chao Wu, Tiancong Shi, Qian Cai, Tianyao Wang, Yingluo Xiong, Yubin Zhang, Wei Jiang, Mingfang Lu, Zhengrong Chen, Jing Chen, Jiqiu Wang, Rui He

Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51): e2303075120. Published online 2023 Dec 15. doi: 10.1073/pnas.2303075120

PMCID:: PMC10743525

Abstract Article PDF–7.0M

Select item 1052399711.

Dendritic cells infected with recombinant adenoviral vector encoding mouse fibroblast activation protein‐α and human livin α exert an antitumor effect against Lewis lung carcinoma in mice

Zaiting Ye, Jiongwei Pan, Zhangyong Yin, Shuanghu Wang, Yuling Li, Xiaoping Cai, Hao Zheng, Zhuo Cao

Immun Inflamm Dis. 2023 Sep; 11(9): e1011. Published online 2023 Sep 27. doi: 10.1002/iid3.1011

PMCID:: PMC10523997

Abstract Article PDF–1.2M

Select item 952512212.

Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models

Ming Qi, Shuran Fan, Maohua Huang, Jinghua Pan, Yong Li, Qun Miao, Wenyu Lyu, Xiaobo Li, Lijuan Deng, Shenghui Qiu, Tongzheng Liu, Weiqing Deng, Xiaodong Chu, Chang Jiang, Wenzhuo He, Liangping Xia, Yunlong Yang, Jian Hong, Qi Qi, Wenqian Yin, Xiangning Liu, Changzheng Shi, Minfeng Chen, Wencai Ye, Dongmei Zhang

J Clin Invest. 2022 Oct 3; 132(19): e157399. Published online 2022 Oct 3. doi: 10.1172/JCI157399

Correction in:: J Clin Invest. 2023 Feb 1; 133(3): e168771.

PMCID:: PMC9525122

Abstract Article PDF–28M

Select item 874644113.

Design, Synthesis and Preclinical Assessment of ^99mTc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging

Diana Trujillo-Benítez, Myrna Luna-Gutiérrez, Guillermina Ferro-Flores, Blanca Ocampo-García, Clara Santos-Cuevas, Gerardo Bravo-Villegas, Enrique Morales-Ávila, Pedro Cruz-Nova, Lorenza Díaz-Nieto, Janice García-Quiroz, Erika Azorín-Vega, Antonio Rosato, Laura Meléndez-Alafort

Molecules. 2022 Jan; 27(1): 264. Published online 2022 Jan 1. doi: 10.3390/molecules27010264

PMCID:: PMC8746441

Abstract Article PDF–3.9M

Select item 831507814.

Molecular imaging of fibroblast activation protein after myocardial infarction using the novel radiotracer [⁶⁸Ga]MHLL1

Laura B.N. Langer, Annika Hess, Zekiye Korkmaz, Jochen Tillmanns, Laura M. Reffert, Jens P. Bankstahl, Frank M. Bengel, James T. Thackeray, Tobias L. Ross

Theranostics. 2021; 11(16): 7755–7766. Published online 2021 Jun 22. doi: 10.7150/thno.51419

PMCID:: PMC8315078

Abstract Article PDF–1.5M

Select item 723783215.

Fibroblast Activation Protein Regulates Lesion Burden and the Fibroinflammatory Response in Apoe-Deficient Mice in a Sexually Dimorphic Manner

James Monslow, Leslie Todd, John E. Chojnowski, Priya K. Govindaraju, Richard K. Assoian, Ellen Puré

Am J Pathol. 2020 May; 190(5): 1118–1136. doi: 10.1016/j.ajpath.2020.01.004

PMCID:: PMC7237832

Abstract Article PDF–5.8M

Select item 529143916.

Fibroblast activation protein is dispensable in the anti-influenza immune response in mice

Sioh-Yang Tan, Sumaiya Chowdhury, Natasa Polak, Mark D. Gorrell, Wolfgang Weninger

PLoS One. 2017; 12(2): e0171194. Published online 2017 Feb 3. doi: 10.1371/journal.pone.0171194

PMCID:: PMC5291439

Abstract Article PDF–1.6M

Select item 469487617.

Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma

Guan-Min Jiang, Wan-Ying Xie, Hong-Sheng Wang, Jun Du, Bai-Ping Wu, Wei Xu, Hui-Fang Liu, Ping Xiao, Zhi-Gang Liu, Hong-Yan Li, Shuang-Quan Liu, Wen-Jun Yin, Qiu-Gui Zhang, Jian-Ping Liang, Hong-Jun Huang

Oncotarget. 2015 Sep 22; 6(28): 25932–25942. Published online 2015 Jul 20. doi: 10.18632/oncotarget.4577

PMCID:: PMC4694876

Abstract Article PDF–4.5M

Select item 314176818.

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

Hyung-Ok Lee, Stefanie R Mullins, Janusz Franco-Barraza, Matthildi Valianou, Edna Cukierman, Jonathan D Cheng

BMC Cancer. 2011; 11: 245. Published online 2011 Jun 13. doi: 10.1186/1471-2407-11-245

PMCID:: PMC3141768

Abstract Article PDF–6.5M

Select item 278679119.

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

Angélica M. Santos, Jason Jung, Nazneen Aziz, Joseph L. Kissil, Ellen Puré

J Clin Invest. 2009 Dec 1; 119(12): 3613–3625. Published online 2009 Nov 16. doi: 10.1172/JCI38988

PMCID:: PMC2786791

Abstract Article PDF–5.6M

Select item 259770020.

Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells

Alanna Kennedy, Huan Dong, Donghai Chen, Wen-Tien Chen

Int J Cancer. Author manuscript; available in PMC 2009 Jan 1.

Published in final edited form as: Int J Cancer. 2009 Jan 1; 124(1): 27–35. doi: 10.1002/ijc.23871

PMCID:: PMC2597700

Abstract Article PDF–2.0M

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