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Items: 1 to 20 of 63

1.
Proximal tubular FHL2, a novel downstream target of hypoxia inducible factor 1, is a protector against ischemic acute kidney injury
Yan Wang, Ziwei Kuang, Xueqi Xing, Yumei Qiu, Jie Zhang, Dandan Shao, Jiaxin Huang, Chunsun Dai, Weichun He
Cell Mol Life Sci. 2024 Dec; 81(1): 244. Published online 2024 May 30. doi: 10.1007/s00018-024-05289-x
PMCID:
PMC11139843
AbstractArticlePDF–17M
2.
FHL2 deficiency impairs follicular development and fertility by attenuating EGF/EGFR/YAP signaling in ovarian granulosa cells
Chen Wang, Hui Sun, John S. Davis, Xiaojie Wang, Lijun Huo, Nan Sun, Qianzhi Huang, Xiangmin Lv, Cheng Wang, Chunbo He, Changjiu He, Yang Zhou, Jiyun Wu, Liguo Yang, Guohua Hua
Cell Death Dis. 2023 Apr; 14(4): 239. Published online 2023 Apr 5. doi: 10.1038/s41419-023-05759-3
PMCID:
PMC10073124
AbstractArticlePDF–5.6M
3.
Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes
Jayron J. Habibe, Maria P. Clemente-Olivo, Torsten P. M. Scheithauer, Elena Rampanelli, Hilde Herrema, Mariska Vos, Arnout Mieremet, Max Nieuwdorp, Daniel H. van Raalte, Etto C. Eringa, Carlie J. M. de Vries
Diabetologia. 2022; 65(10): 1721–1733. Published online 2022 Jul 8. doi: 10.1007/s00125-022-05750-1
PMCID:
PMC9477948
AbstractArticlePDF–2.5M
4.
Deletion of the FHL2 gene attenuates intima‐media thickening in a partially ligated carotid artery ligated mouse model
Chi‐Yu Chen, Hsiao‐Ya Tsai, Shih‐Hung Tsai, Pao‐Hsien Chu, Po‐Hsun Huang, Jaw‐Wen Chen, Shing‐Jong Lin
J Cell Mol Med. 2020 Jan; 24(1): 160–173. Published online 2019 Nov 12. doi: 10.1111/jcmm.14687
PMCID:
PMC6933399
AbstractArticlePDF–2.2M
5.
The LIM-Only Protein FHL2 Reduces Vascular Lesion Formation Involving Inhibition of Proliferation and Migration of Smooth Muscle Cells
Kondababu Kurakula, Mariska Vos, Iker Otermin Rubio, Goran Marinković, Reinhard Buettner, Lukas C. Heukamp, Jan Stap, Vivian de Waard, Claudia M. van Tiel, Carlie J.M. de Vries
PLoS One. 2014; 9(4): e94931. Published online 2014 Apr 15. doi: 10.1371/journal.pone.0094931
PMCID:
PMC3988136
AbstractArticlePDF–6.5M
6.
The Four and a Half LIM-Domain 2 Controls Early Cardiac Cell Commitment and Expansion Via Regulating β-Catenin-Dependent Transcription
Anke Renger, Maria-Patapia Zafiriou, Claudia Noack, Elena Pavlova, Alexander Becker, Krasimira Sharkova, Martin W Bergmann, Ali El-Armouche, Wolfram-Hubertus Zimmermann, Laura C Zelarayán
Stem Cells. 2013 May; 31(5): 928–940. Published online 2013 Jan 22. doi: 10.1002/stem.1332
PMCID:
PMC3744766
AbstractArticlePDF–1.2M
7.
Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates liver fibrosis in mice
Sebastian Huss, Christian Stellmacher, Diane Goltz, Inna Khlistunova, Alexander C Adam, Jonel Trebicka, Jutta Kirfel, Reinhard Büttner, Ralf Weiskirchen
BMC Gastroenterol. 2013; 13: 8. Published online 2013 Jan 14. doi: 10.1186/1471-230X-13-8
PMCID:
PMC3562203
AbstractArticlePDF–1.9M
8.
Disruption of Four-and-a-Half LIM 2 Decreases Bone Mineral Content and Bone Mineral Density in Femur and Tibia Bones of Female Mice
K. E. Govoni, D. J. Baylink, J. Chen, S. Mohan
Calcif Tissue Int. Author manuscript; available in PMC 2010 Jul 14.
Published in final edited form as: Calcif Tissue Int. 2006 Aug; 79(2): 112–117. Published online 2006 Aug 15. doi: 10.1007/s00223-006-0074-7
PMCID:
PMC2903958
AbstractArticlePDF–233K
9.
Deletion of the FHL2 Gene Attenuating Neovascularization after Corneal Injury
Pao-Hsien Chu, Lung-Kun Yeh, Hsin-Chiung Lin, Shih-Ming Jung, David Hui-Kang Ma, I-Jong Wang, Hsueh-Hua Wu, Tzu-Fang Shiu, Ju Chen
Invest Ophthalmol Vis Sci. Author manuscript; available in PMC 2009 Dec 1.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2008 Dec; 49(12): 5314–5318. Published online 2008 Aug 15. doi: 10.1167/iovs.08-2209
PMCID:
PMC2738584
AbstractArticlePDF–1.2M
10.
Deficiency in the LIM-only protein Fhl2 impairs skin wound healing
Viktor Wixler, Stephanie Hirner, Judith M. Müller, Lucia Gullotti, Carola Will, Jutta Kirfel, Thomas Günther, Holm Schneider, Anja Bosserhoff, Hubert Schorle, Jung Park, Roland Schüle, Reinhard Buettner
J Cell Biol. 2007 Apr 9; 177(1): 163–172. doi: 10.1083/jcb.200606043
PMCID:
PMC2064120
AbstractArticlePDF–2.1M
11.
FHL2 (SLIM3) Is Not Essential for Cardiac Development and Function
Po-Hsien Chu, Wendy M. Bardwell, Yusu Gu, John Ross, Jr., Ju Chen
Mol Cell Biol. 2000 Oct; 20(20): 7460–7462. doi: 10.1128/mcb.20.20.7460-7462.2000
PMCID:
PMC86299
AbstractArticlePDF–119K
12.
Four-and-a-Half LIM-Domain Protein 2 (FHL2) Induces Neuropeptide Y (NPY) in Macrophages in Visceral Adipose Tissue and Promotes Diet-Induced Obesity
Judith Sommer, Hanna Ehnis, Tatjana Seitz, Julia Schneider, Andreas B. Wild, Sandra Moceri, Christa Buechler, Aline Bozec, Georg F. Weber, Susanne Merkel, Ruth Beckervordersandforth, Alexander Steinkasserer, Roland Schüle, Jonel Trebicka, Arndt Hartmann, Anja Bosserhoff, Stephan von Hörsten, Peter Dietrich, Claus Hellerbrand
Int J Mol Sci. 2023 Oct; 24(19): 14943. Published online 2023 Oct 6. doi: 10.3390/ijms241914943
PMCID:
PMC10573629
AbstractArticlePDF–3.0M
13.
LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis
Chantal Kroone, Mariska Vos, Timo Rademakers, Marijke Kuijpers, Mark Hoogenboezem, Jaap van Buul, Johan W.M. Heemskerk, Wolfram Ruf, Astrid van Hylckama Vlieg, Henri H. Versteeg, Marie-José Goumans, Carlie J.M. de Vries, Kondababu Kurakula, INVENT Consortium
Haematologica. 2020 Jun; 105(6): 1677–1685. Prepublished online 2019 Aug 29. doi: 10.3324/haematol.2018.203026
PMCID:
PMC7271603
AbstractArticlePDF–3.5M
14.
Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury
Judith Sommer, Christoph Dorn, Erwin Gäbele, Frauke Bataille, Kim Freese, Tatjana Seitz, Wolfgang E. Thasler, Reinhard Büttner, Ralf Weiskirchen, Anja Bosserhoff, Claus Hellerbrand
Cells. 2020 Jan; 9(1): 248. Published online 2020 Jan 19. doi: 10.3390/cells9010248
PMCID:
PMC7016690
AbstractArticlePDF–1.9M
15.
LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor β1 Expression
Jennifer Dahan, Florence Levillayer, Tian Xia, Yann Nouët, Catherine Werts, Martine Fanton d'Andon, Minou Adib-Conquy, Anne-Marie Cassard-Doulcier, Varun Khanna, Ju Chen, Thierry Tordjmann, Marie-Annick Buendia, Grégory Jouvion, Yu Wei
Mol Cell Biol. 2017 May 15; 37(10): e00636-16. Prepublished online 2017 Feb 21. Published online 2017 May 2. doi: 10.1128/MCB.00636-16
PMCID:
PMC5477553
AbstractArticlePDF–3.5M
16.
Four-and-a-Half LIM Domains Protein 2 Is a Coactivator of Wnt Signaling in Diabetic Kidney Disease
Szu-Yuan Li, Po-Hsun Huang, Der-Cherng Tarng, Tzu-Ping Lin, Wu-Chang Yang, Yen-Hwa Chang, An-Hang Yang, Chih-Ching Lin, Muh-Hwa Yang, Jaw-Wen Chen, Geert W. Schmid-Schönbein, Shu Chien, Pao-Hsien Chu, Shing-Jong Lin
J Am Soc Nephrol. 2015 Dec; 26(12): 3072–3084. Published online 2015 Apr 8. doi: 10.1681/ASN.2014100989
PMCID:
PMC4657839
AbstractArticle
17.
FHL2 regulates hematopoietic stem cell functions under stress conditions
Yu Hou, Xiaoqin Wang, LiPing Li, Rong Fan, Ju Chen, Tongyu Zhu, Wen Li, Yanwen Jiang, Nupur Mittal, Wenshu Wu, David Peace, Zhijian Qian
Leukemia. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Leukemia. 2015 Mar; 29(3): 615–624. Published online 2014 Sep 2. doi: 10.1038/leu.2014.254
PMCID:
PMC4346553
AbstractArticlePDF–757K
18.
The LIM-Only Protein FHL2 Attenuates Lung Inflammation during Bleomycin-Induced Fibrosis
Abdulaleem Alnajar, Carolin Nordhoff, Tanja Schied, Ruth Chiquet-Ehrismann, Karin Loser, Thomas Vogl, Stephan Ludwig, Viktor Wixler
PLoS One. 2013; 8(11): e81356. Published online 2013 Nov 18. doi: 10.1371/journal.pone.0081356
PMCID:
PMC3832604
AbstractArticlePDF–3.7M
19.
LIM-Only Protein FHL2 Activates NF-κB Signaling in the Control of Liver Regeneration and Hepatocarcinogenesis
Jennifer Dahan, Yann Nouët, Grégory Jouvion, Florence Levillayer, Minou Adib-Conquy, Anne-Marie Cassard-Doulcier, Ali Tebbi, Fany Blanc, Lauriane Remy, Ju Chen, Stefano Cairo, Catherine Werts, Mustapha Si-Tahar, Thierry Tordjmann, Marie-Annick Buendia, Yu Wei
Mol Cell Biol. 2013 Aug; 33(16): 3299–3308. doi: 10.1128/MCB.00105-13
PMCID:
PMC3753919
AbstractArticlePDF–2.7M
20.
The LIM-only Protein FHL2 Regulates Cyclin D1 Expression and Cell Proliferation
Charlotte Labalette, Yann Nouët, Joëlle Sobczak-Thepot, Carolina Armengol, Florence Levillayer, Marie-Claude Gendron, Claire-Angélique Renard, Béatrice Regnault, Ju Chen, Marie-Annick Buendia, Yu Wei
J Biol Chem. 2008 May 30; 283(22): 15201–15208. doi: 10.1074/jbc.M800708200
PMCID:
PMC3258904
AbstractArticlePDF–562K

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