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Select item 84155211.

Circulating Maternal sFLT1 (Soluble fms-Like Tyrosine Kinase-1) Is Sufficient to Impair Spiral Arterial Remodeling in a Preeclampsia Mouse Model

Rebekka Vogtmann, Jacqueline Heupel, Florian Herse, Mahsa Matin, Henning Hagmann, Ivo Bendix, Kristin Kräker, Ralf Dechend, Elke Winterhager, Rainer Kimmig, Angela Köninger, Alexandra Gellhaus

Hypertension. 2021 Oct; 78(4): 1067–1079. Published online 2021 Aug 15. doi: 10.1161/HYPERTENSIONAHA.121.17567

PMCID:: PMC8415521

Abstract Article PDF–4.8M

Select item 80027052.

The Ablation of VEGFR-1 Signaling Promotes Pressure Overload-Induced Cardiac Dysfunction and Sudden Death

Annakaisa Tirronen, Nicholas L. Downes, Jenni Huusko, Johanna P. Laakkonen, Tomi Tuomainen, Pasi Tavi, Marja Hedman, Seppo Ylä-Herttuala

Biomolecules. 2021 Mar; 11(3): 452. Published online 2021 Mar 17. doi: 10.3390/biom11030452

PMCID:: PMC8002705

Abstract Article PDF–16M

Select item 73472843.

VEGFR1-Targeted Contrast-Enhanced Ultrasound Imaging Quantification of Vasculogenic Mimicry Microcirculation in a Mouse Model of Choroidal Melanoma

Haiyun Liu, Min Gao, Jiying Gu, Xiaoling Wan, Hong Wang, Qing Gu, Yifan Zhou, Xiaodong Sun

Transl Vis Sci Technol. 2020 Feb; 9(3): 4. Published online 2020 Feb 7. doi: 10.1167/tvst.9.3.4

PMCID:: PMC7347284

Abstract Article PDF–9.4M

Select item 65049184.

VEGF Receptor 1-Expressing Macrophages Recruited from Bone Marrow Enhances Angiogenesis in Endometrial Tissues

Kazuki Sekiguchi, Yoshiya Ito, Kyoko Hattori, Tomoyoshi Inoue, Kanako Hosono, Masako Honda, Akiko Numao, Hideki Amano, Masabumi Shibuya, Nobuya Unno, Masataka Majima

Sci Rep. 2019; 9: 7037. Published online 2019 May 7. doi: 10.1038/s41598-019-43185-8

PMCID:: PMC6504918

Abstract Article PDF–5.2M

Select item 54535035.

VEGF₁₆₅b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease

Vijay Chaitanya Ganta, Min Choi, Anna Kutateladze, Brian H. Annex

Circ Res. Author manuscript; available in PMC 2018 Jan 20.

Published in final edited form as: Circ Res. 2017 Jan 20; 120(2): 282–295. Published online 2016 Dec 14. doi: 10.1161/CIRCRESAHA.116.309516

PMCID:: PMC5453503

Abstract Article PDF–1.3M

Select item 49227176.

Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia

Suzanne D. Burke, Zsuzsanna K. Zsengellér, Eliyahu V. Khankin, Agnes S. Lo, Augustine Rajakumar, Jennifer J. DuPont, Amy McCurley, Mary E. Moss, Dongsheng Zhang, Christopher D. Clark, Alice Wang, Ellen W. Seely, Peter M. Kang, Isaac E. Stillman, Iris Z. Jaffe, S. Ananth Karumanchi

J Clin Invest. 2016 Jul 1; 126(7): 2561–2574. Published online 2016 Jun 6. doi: 10.1172/JCI83918

PMCID:: PMC4922717

Abstract Article PDF–3.1M

Select item 49091637.

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation

John C. Chappell, Julia G. Cluceru, Jessica E. Nesmith, Kevin P. Mouillesseaux, Vanessa B. Bradley, Caitlin M. Hartland, Yasmin L. Hashambhoy-Ramsay, Joseph Walpole, Shayn M. Peirce, Feilim Mac Gabhann, Victoria L. Bautch

Cardiovasc Res. 2016 Jul 1; 111(1): 84–93. Published online 2016 May 3. doi: 10.1093/cvr/cvw091

PMCID:: PMC4909163

Abstract Article PDF–1.2M

Select item 41465448.

VEGFR1-Positive Macrophages Facilitate Liver Repair and Sinusoidal Reconstruction after Hepatic Ischemia/Reperfusion Injury

Hirotoki Ohkubo, Yoshiya Ito, Tsutomu Minamino, Koji Eshima, Ken Kojo, Shin-ichiro Okizaki, Mitsuhiro Hirata, Masabumi Shibuya, Masahiko Watanabe, Masataka Majima

PLoS One. 2014; 9(8): e105533. Published online 2014 Aug 27. doi: 10.1371/journal.pone.0105533

PMCID:: PMC4146544

Abstract Article PDF–3.2M

Select item 38654859.

VEGFR-1 Regulates Adult Olfactory Bulb Neurogenesis and Migration of Neural Progenitors in the Rostral Migratory Stream In Vivo

Ina M. Wittko, Anne Schänzer, Andrey Kuzmichev, Fabian T. Schneider, Masabumi Shibuya, Sabine Raab, Karl H. Plate

J Neurosci. 2009 Jul 8; 29(27): 8704–8714. doi: 10.1523/JNEUROSCI.5527-08.2009

PMCID:: PMC3865485

Abstract Article PDF–2.5M

Select item 382904510.

Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model

Astrid Bergmann, Shakil Ahmad, Melissa Cudmore, Achim D Gruber, Petra Wittschen, Werner Lindenmaier, Gerhard Christofori, Volkmar Gross, Andrey Ch da Costa Gonzalves, Hermann-Josef Gröne, Asif Ahmed, Herbert A Weich

J Cell Mol Med. 2010 Jun; 14(6b): 1857–1867. Published online 2009 Jun 16. doi: 10.1111/j.1582-4934.2009.00820.x

PMCID:: PMC3829045

Abstract Article PDF–1.0M

Select item 329067311.

Hemodynamic, Vascular, and Reproductive Impact of FMS-Like Tyrosine Kinase 1 (FLT1) Blockade on the Uteroplacental Circulation During Normal Mouse Pregnancy

Eliyahu V. Khankin, Maurizio Mandala, Ilsley Colton, S. Ananth Karumanchi, George Osol

Biol Reprod. 2012 Feb; 86(2): 57. Published online 2011 Nov 9. doi: 10.1095/biolreprod.111.095380

PMCID:: PMC3290673

Abstract Article PDF–454K

Select item 320401812.

VEGFR-1 Mediates Endothelial Differentiation and Formation of Blood Vessels in a Murine Model of Infantile Hemangioma

Elisa Boscolo, John B. Mulliken, Joyce Bischoff

Am J Pathol. 2011 Nov; 179(5): 2266–2277. doi: 10.1016/j.ajpath.2011.07.040

PMCID:: PMC3204018

Abstract Article PDF–3.8M

Select item 274427913.

VEGFR1 Activity Modulates Myeloid Cell Infiltration in Growing Lung Metastases but Is Not Required for Spontaneous Metastasis Formation

Michelle R. Dawson, Dan G. Duda, Sung-Suk Chae, Dai Fukumura, Rakesh K. Jain

PLoS One. 2009; 4(9): e6525. Published online 2009 Sep 18. doi: 10.1371/journal.pone.0006525

PMCID:: PMC2744279

Abstract Article PDF–3.7M

Select item 192446914.

VEGFR1 (Flt-1^+/−) GENE KNOCKOUT LEADS TO THE DISRUPTION OF VEGF MEDIATED SIGNALING THROUGH NITRIC OXIDE/HEMEOXYGENASE PATHWAY IN ISCHEMIC PRECONDITIONED MYOCARDIUM

Mahesh Thirunavukkarasu, Bela Juhasz, Lijun Zhan, Venugopal P Menon, Arpad Tosaki, Hajime Otani, Nilanjana Maulik

Free Radic Biol Med. Author manuscript; available in PMC 2008 May 15.

Published in final edited form as: Free Radic Biol Med. 2007 May 15; 42(10): 1487–1495. Published online 2007 Feb 20. doi: 10.1016/j.freeradbiomed.2007.02.011

PMCID:: PMC1924469

Abstract Article PDF–822K

Select item 179406915.

Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation

Gefei Zeng, Sarah M. Taylor, Janet R. McColm, Nicholas C. Kappas, Joseph B. Kearney, Lucy H. Williams, Mary E. Hartnett, Victoria L. Bautch

Blood. 2007 Feb 15; 109(4): 1345–1352. Prepublished online 2006 Oct 26. doi: 10.1182/blood-2006-07-037952

PMCID:: PMC1794069

Abstract Article

Select item 978275616.

Absence of VEGFR-1/Flt-1 signaling pathway in mice results in insensitivity to discogenic low back pain in an established disc injury mouse model

Sujun Qiu, Changgui Shi, Arivarasu Natarajan Anbazhagan, Vaskar Das, Vipin Arora, Ranjan Kc, Xin Li, InSug O-Sullivan, Andre van Wijnen, Sudhakar Chintharlapalli, Gina Gott-Velis, Ripper Richard, Fackson Mwale, Masabumi Shibuya, Shaoxiong Min, Hee-Jeong Im

J Cell Physiol. Author manuscript; available in PMC 2022 Dec 23.

Published in final edited form as: J Cell Physiol. 2020 Jun; 235(6): 5305–5317. Published online 2019 Dec 25. doi: 10.1002/jcp.29416

Correction in:: J Cell Physiol. 2024 Apr 29

PMCID:: PMC9782756

Abstract Article PDF–1.6M

Select item 936615417.

Reducing VEGFB expression regulates the balance of glucose and lipid metabolism in mice via VEGFR1

Xu Luo, Rong-Rong Li, Yu-Qi Li, Han-Pu Yu, Hai-Ning Yu, Wen-Guo Jiang, Ya-Na Li

Mol Med Rep. 2022 Sep; 26(3): 285. Published online 2022 Jul 26. doi: 10.3892/mmr.2022.12801

PMCID:: PMC9366154

Abstract Article PDF–7.2M

Select item 931560918.

Knockdown of VEGFB/VEGFR1 Signaling Promotes White Adipose Tissue Browning and Skeletal Muscle Development

Mingfa Ling, Xumin Lai, Lulu Quan, Fan Li, Limin Lang, Yiming Fu, Shengchun Feng, Xin Yi, Canjun Zhu, Ping Gao, Xiaotong Zhu, Lina Wang, Gang Shu, Qingyan Jiang, Songbo Wang

Int J Mol Sci. 2022 Jul; 23(14): 7524. Published online 2022 Jul 7. doi: 10.3390/ijms23147524

PMCID:: PMC9315609

Abstract Article PDF–2.6M

Select item 667382419.

Vascular Endothelial Growth Factor Directly Inhibits Primitive Neural Stem Cell Survival But Promotes Definitive Neural Stem Cell Survival

Tamaki Wada, Jody J. Haigh, Masatsugu Ema, Seiji Hitoshi, Radha Chaddah, Janet Rossant, Andras Nagy, Derek van der Kooy

J Neurosci. 2006 Jun 21; 26(25): 6803–6812. doi: 10.1523/JNEUROSCI.0526-06.2006

PMCID:: PMC6673824

Abstract Article PDF–473K

Select item 667132620.

Novel Role for Vascular Endothelial Growth Factor (VEGF) Receptor-1 and Its Ligand VEGF-B in Motor Neuron Degeneration

Koen Poesen, Diether Lambrechts, Philip Van Damme, Joke Dhondt, Florian Bender, Nicolas Frank, Elke Bogaert, Bart Claes, Line Heylen, An Verheyen, Katrien Raes, Marc Tjwa, Ulf Eriksson, Masabumi Shibuya, Rony Nuydens, Ludo Van Den Bosch, Theo Meert, Rudi D'Hooge, Michael Sendtner, Wim Robberecht, Peter Carmeliet

J Neurosci. 2008 Oct 15; 28(42): 10451–10459. doi: 10.1523/JNEUROSCI.1092-08.2008

Correction in:: J Neurosci. 2008 Dec 17; 28(51): np.

PMCID:: PMC6671326

Abstract Article PDF–343K

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