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Select item 107268771.

Distinct physiological characteristics and altered glucagon signaling in GHRH knockout mice: Implications for longevity

A. Tate Lasher, Liou Y. Sun

Aging Cell. 2023 Dec; 22(12): e13985. Published online 2023 Sep 4. doi: 10.1111/acel.13985

PMCID:: PMC10726877

Abstract Article PDF–2.6M

Select item 106701142.

Effects of GHRH Deficiency and GHRH Antagonism on Emotional Disorders in Mice

Lucia Recinella, Maria Loreta Libero, Serena Veschi, Anna Piro, Guya Diletta Marconi, Francesca Diomede, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Rosalba Florio, Alessia Lamolinara, Renzhi Cai, Wei Sha, Andrew V. Schally, Roberto Salvatori, Luigi Brunetti, Sheila Leone

Cells. 2023 Nov; 12(22): 2615. Published online 2023 Nov 12. doi: 10.3390/cells12222615

PMCID:: PMC10670114

Abstract Article PDF–2.1M

Select item 86175253.

Agonistic analog of growth hormone–releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke

Yueyang Liu, Jingyu Yang, Xiaohang Che, Jianhua Huang, Xianyang Zhang, Xiaoxiao Fu, Jialing Cai, Yang Yao, Haotian Zhang, Ruiping Cai, Xiaomin Su, Qian Xu, Fu Ren, Renzhi Cai, Andrew V. Schally, Ming-Sheng Zhou

Proc Natl Acad Sci U S A. 2021 Nov 23; 118(47): e2109600118. Published online 2021 Nov 15. doi: 10.1073/pnas.2109600118

PMCID:: PMC8617525

Abstract Article PDF–2.4M

Select item 70669194.

Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism

Jessica M. Hoffman, Aliza Poonawalla, Mert Icyuz, William R. Swindell, Landon Wilson, Stephen Barnes, Liou Y. Sun

Aging (Albany NY) 2020 Feb 29; 12(4): 3473–3485. Published online 2020 Feb 23. doi: 10.18632/aging.102822

PMCID:: PMC7066919

Abstract Article PDF–1.3M

Select item 59978965.

The Severe Deficiency of the Somatotrope GH-Releasing Hormone/Growth Hormone/Insulin-Like Growth Factor 1 Axis of Ghrh^−/− Mice Is Associated With an Important Splenic Atrophy and Relative B Lymphopenia

Gwennaelle Bodart, Khalil Farhat, Chantal Renard-Charlet, Guillaume Becker, Alain Plenevaux, Roberto Salvatori, Vincent Geenen, Henri Martens

Front Endocrinol (Lausanne) 2018; 9: 296. Published online 2018 Jun 6. doi: 10.3389/fendo.2018.00296

PMCID:: PMC5997896

Abstract Article PDF–1.6M

Select item 48084676.

Profound actions of an agonist of growth hormone releasing hormone on angiogenic therapy by mesenchymal stem cells

Qunchao Ma, Xiangyang Xia, Quanwei Tao, Kai Lu, Jian Shen, Qiyuan Xu, Xinyang Hu, Yaoliang Tang, Norman L. Block, Keith A Webster, Andrew V. Schally, Jian'an Wang, Hong Yu

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Apr; 36(4): 663–672. Published online 2016 Feb 11. doi: 10.1161/ATVBAHA.116.307126

PMCID:: PMC4808467

Abstract Article PDF–1.3M

Select item 38107837.

Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice

Liou Y Sun, Adam Spong, William R Swindell, Yimin Fang, Cristal Hill, Joshua A Huber, Jacob D Boehm, Reyhan Westbrook, Roberto Salvatori, Andrzej Bartke

eLife. 2013; 2: e01098. Published online 2013 Oct 29. doi: 10.7554/eLife.01098

PMCID:: PMC3810783

Abstract Article PDF–5.6M

Select item 30097568.

Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice

William A. Banks, John E. Morley, Susan A. Farr, Tulin O. Price, Nuran Ercal, Irving Vidaurre, Andrew V. Schally

Proc Natl Acad Sci U S A. 2010 Dec 21; 107(51): 22272–22277. Published online 2010 Dec 6. doi: 10.1073/pnas.1016369107

PMCID:: PMC3009756

Abstract Article PDF–668K

Select item 29729409.

Acceleration of wound healing by growth hormone-releasing hormone and its agonists

Nikolina Dioufa, Andrew V. Schally, Ioulia Chatzistamou, Evi Moustou, Norman L. Block, Gary K. Owens, Athanasios G. Papavassiliou, Hippokratis Kiaris

Proc Natl Acad Sci U S A. 2010 Oct 26; 107(43): 18611–18615. Published online 2010 Oct 11. doi: 10.1073/pnas.1013942107

PMCID:: PMC2972940

Abstract Article PDF–756K

Select item 2474410.

Growth hormone-releasing hormone: An autocrine growth factor for small cell lung carcinoma

H. Kiaris, A. V. Schally, J. L. Varga, K. Groot, P. Armatis

Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26): 14894–14898. doi: 10.1073/pnas.96.26.14894

PMCID:: PMC24744

Abstract Article PDF–117K

Select item 814761511.

ARC^GHR Neurons Regulate Muscle Glucose Uptake

Juliana Bezerra Medeiros de Lima, Lucas Kniess Debarba, Alan C. Rupp, Nathan Qi, Chidera Ubah, Manal Khan, Olesya Didyuk, Iven Ayyar, Madelynn Koch, Darleen A. Sandoval, Marianna Sadagurski

Cells. 2021 May; 10(5): 1093. Published online 2021 May 3. doi: 10.3390/cells10051093

PMCID:: PMC8147615

Abstract Article PDF–3.1M

Select item 617608412.

Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae

Khalil Farhat, Gwennaëlle Bodart, Chantal Charlet-Renard, Christophe J. Desmet, Michel Moutschen, Yves Beguin, Frédéric Baron, Pierrette Melin, Pascale Quatresooz, Anne-Simone Parent, Daniel Desmecht, Jean-Claude Sirard, Roberto Salvatori, Henri Martens, Vincent G. Geenen

Front Immunol. 2018; 9: 2175. Published online 2018 Oct 2. doi: 10.3389/fimmu.2018.02175

PMCID:: PMC6176084

Abstract Article PDF–4.6M

Select item 513335813.

Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice

Justin Darcy, Samuel McFadden, Yimin Fang, Joshua A. Huber, Chi Zhang, Liou Y. Sun, Andrzej Bartke

Endocrinology. 2016 Dec; 157(12): 4744–4753. Published online 2016 Oct 14. doi: 10.1210/en.2016-1593

PMCID:: PMC5133358

Abstract Article

Select item 382262714.

Growth hormone releasing hormone induces the expression of nitric oxide synthase

Nektarios Barabutis, Agnieszka Siejka, Andrew V Schally

J Cell Mol Med. 2011 May; 15(5): 1148–1155. Published online 2010 May 26. doi: 10.1111/j.1582-4934.2010.01096.x

PMCID:: PMC3822627

Abstract Article PDF–655K

Select item 772413815.

ERα Signaling in GHRH/Kiss1 Dual-Phenotype Neurons Plays Sex-Specific Roles in Growth and Puberty

David Garcia-Galiano, Alexandra L. Cara, Zachary Tata, Susan J. Allen, Martin G. Myers, Jr, Ernestina Schipani, Carol F. Elias

J Neurosci. 2020 Dec 2; 40(49): 9455–9466. doi: 10.1523/JNEUROSCI.2069-20.2020

PMCID:: PMC7724138

Abstract Article PDF–5.3M

Select item 725248516.

Tyrosine Hydroxylase Neurons Regulate Growth Hormone Secretion via Short-Loop Negative Feedback

Frederick Wasinski, João A.B. Pedroso, Willian O. dos Santos, Isadora C. Furigo, David Garcia-Galiano, Carol F. Elias, Edward O. List, John J. Kopchick, Raphael E. Szawka, Jose Donato, Jr

J Neurosci. 2020 May 27; 40(22): 4309–4322. doi: 10.1523/JNEUROSCI.2531-19.2020

PMCID:: PMC7252485

Abstract Article PDF–5.7M

Select item 457245517.

The somatotropic axis and longevity in mice

H. M. Brown-Borg

Am J Physiol Endocrinol Metab. 2015 Sep 15; 309(6): E503–E510. Published online 2015 Jul 28. doi: 10.1152/ajpendo.00262.2015

PMCID:: PMC4572455

Abstract Article

Select item 141370318.

An essential role for the hematopoietic transcription factor Ikaros in hypothalamic–pituitary-mediated somatic growth

Shereen Ezzat, Rene Mader, Sandra Fischer, ShunJiang Yu, Cameron Ackerley, Sylvia L. Asa

Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7): 2214–2219. Published online 2006 Feb 7. doi: 10.1073/pnas.0508565103

PMCID:: PMC1413703

Abstract Article PDF–544K

Select item 2464219.

Functional growth hormone (GH) receptors and GH are expressed by preimplantation mouse embryos: A role for GH in early embryogenesis?

M. Pantaleon, E. J. Whiteside, M. B. Harvey, R. T. Barnard, M. J. Waters, P. L. Kaye

Proc Natl Acad Sci U S A. 1997 May 13; 94(10): 5125–5130. doi: 10.1073/pnas.94.10.5125

PMCID:: PMC24642

Abstract Article PDF–380K

Select item 603409620.

Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance

Alan C. Rupp, Margaret B. Allison, Justin C. Jones, Christa M. Patterson, Chelsea L. Faber, Nadejda Bozadjieva, Lora K. Heisler, Randy J. Seeley, David P. Olson, Martin G. Myers, Jr.

Mol Metab. 2018 Aug; 14: 130–138. Published online 2018 Jun 6. doi: 10.1016/j.molmet.2018.06.001