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Select item 66729741.

Fate-Mapping the Mammalian Hindbrain: Segmental Origins of Vestibular Projection Neurons Assessed Using Rhombomere-Specific Hoxa2 Enhancer Elements in the Mouse Embryo

Massimo Pasqualetti, Carmen Díaz, Jean-Sébastien Renaud, Filippo M. Rijli, Joel C. Glover

J Neurosci. 2007 Sep 5; 27(36): 9670–9681. doi: 10.1523/JNEUROSCI.2189-07.2007

PMCID:: PMC6672974

Abstract Article PDF–1.2M

Select item 38216202.

Molecular Study of a Hoxa2 Gain-of-Function in Chondrogenesis: A Model of Idiopathic Proportionate Short Stature

Pierre M. L. Deprez, Miloud G. Nichane, Benoît G. Lengelé, René Rezsöhazy, Catherine Nyssen-Behets

Int J Mol Sci. 2013 Oct; 14(10): 20386–20398. Published online 2013 Oct 14. doi: 10.3390/ijms141020386

PMCID:: PMC3821620

Abstract Article PDF–2.1M

Select item 26293493.

A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2

Stefan Tümpel, Francisco Cambronero, Carrie Sims, Robb Krumlauf, Leanne M. Wiedemann

Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51): 20077–20082. Published online 2008 Dec 22. doi: 10.1073/pnas.0806360105

PMCID:: PMC2629349

Abstract Article PDF–811K

Select item 494844.

Murine Hox-1.11 homeobox gene structure and expression.

D P Tan, J Ferrante, A Nazarali, X Shao, C A Kozak, V Guo, M Nirenberg

Proc Natl Acad Sci U S A. 1992 Jul 15; 89(14): 6280–6284. doi: 10.1073/pnas.89.14.6280

PMCID:: PMC49484

Summary Page Browse PDF–1.3M

Select item 36500445.

Differential Distribution of the Ca (2+) Regulator Pcp4 in the Branchial Arches Is Regulated by Hoxa2

Megan Anderson, Shilu Amin, Fabiana Luise, Leo Zeef, Nicoletta Bobola

PLoS One. 2013; 8(5): e63160. Published online 2013 May 9. doi: 10.1371/journal.pone.0063160

PMCID:: PMC3650044

Abstract Article PDF–513K

Select item 20987666.

Distinct roles of Hoxa2 and Krox20 in the development of rhythmic neural networks controlling inspiratory depth, respiratory frequency, and jaw opening

Fabrice Chatonnet, Ludovic J Wrobel, Valérie Mézières, Massimo Pasqualetti, Sébastien Ducret, Emmanuel Taillebourg, Patrick Charnay, Filippo M Rijli, Jean Champagnat

Neural Develop. 2007; 2: 19. Published online 2007 Sep 26. doi: 10.1186/1749-8104-2-19

PMCID:: PMC2098766

Abstract Article PDF–844K

Select item 102417897.

A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest

Sandra Kessler, Maryline Minoux, Onkar Joshi, Yousra Ben Zouari, Sebastien Ducret, Fiona Ross, Nathalie Vilain, Adwait Salvi, Joachim Wolff, Hubertus Kohler, Michael B. Stadler, Filippo M. Rijli

Nat Commun. 2023; 14: 3242. Published online 2023 Jun 5. doi: 10.1038/s41467-023-38953-0

PMCID:: PMC10241789

Abstract Article PDF–6.6M

Select item 88839958.

Different Ectopic Hoxa2 Expression Levels in Mouse Cranial Neural Crest Cells Result in Distinct Craniofacial Anomalies and Homeotic Phenotypes

Taro Kitazawa, Maryline Minoux, Sebastien Ducret, Filippo M. Rijli

J Dev Biol. 2022 Mar; 10(1): 9. Published online 2022 Jan 31. doi: 10.3390/jdb10010009

PMCID:: PMC8883995

Abstract Article PDF–2.2M

Select item 77696179.

HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation

Laure Bridoux, Peyman Zarrineh, Joshua Mallen, Mike Phuycharoen, Victor Latorre, Frank Ladam, Marta Losa, Syed Murtuza Baker, Charles Sagerstrom, Kimberly A. Mace, Magnus Rattray, Nicoletta Bobola

PLoS Genet. 2020 Dec; 16(12): e1009162. Published online 2020 Dec 14. doi: 10.1371/journal.pgen.1009162

PMCID:: PMC7769617

Abstract Article PDF–2.2M

Select item 952986110.

Fgf8 dosage regulates jaw shape and symmetry through pharyngeal‐cardiac tissue relationships

Nathaniel Zbasnik, Katie Dolan, Stephanie A. Buczkowski, Rebecca M. Green, Benedikt Hallgrímsson, Ralph S. Marcucio, Anne M. Moon, Jennifer L. Fish

Dev Dyn. 2022 Oct; 251(10): 1711–1727. Published online 2022 Jun 9. doi: 10.1002/dvdy.501

PMCID:: PMC9529861

Abstract Article PDF–9.6M

Select item 570449811.

Six2 Plays an Intrinsic Role in Regulating Proliferation of Mesenchymal Cells in the Developing Palate

Dennis O. Okello, Paul P. R. Iyyanar, William M. Kulyk, Tara M. Smith, Scott Lozanoff, Shaoping Ji, Adil J. Nazarali

Front Physiol. 2017; 8: 955. Published online 2017 Nov 23. doi: 10.3389/fphys.2017.00955

PMCID:: PMC5704498

Abstract Article PDF–3.2M

Select item 416235912.

Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development

Nikolaos Mandalos, Muriel Rhinn, Zoraide Granchi, Ioannis Karampelas, Thimios Mitsiadis, Aris N. Economides, Pascal Dollé, Eumorphia Remboutsika

Front Physiol. 2014; 5: 345. Published online 2014 Sep 12. doi: 10.3389/fphys.2014.00345

PMCID:: PMC4162359

Abstract Article PDF–1.4M

Select item 335118213.

Genome-wide occupancy links Hoxa2 to Wnt–β-catenin signaling in mouse embryonic development

Ian J. Donaldson, Shilu Amin, James J. Hensman, Eva Kutejova, Magnus Rattray, Neil Lawrence, Andrew Hayes, Christopher M. Ward, Nicoletta Bobola

Nucleic Acids Res. 2012 May; 40(9): 3990–4001. Published online 2012 Jan 2. doi: 10.1093/nar/gkr1240

PMCID:: PMC3351182

Abstract Article PDF–8.5M

Select item 306791114.

Transient Activation of Meox1 Is an Early Component of the Gene Regulatory Network Downstream of Hoxa2

Pavel Kirilenko, Guiyuan He, Baljinder S. Mankoo, Moises Mallo, Richard Jones, Nicoletta Bobola

Mol Cell Biol. 2011 Mar; 31(6): 1301–1308. Published online 2011 Jan 18. doi: 10.1128/MCB.00705-10

PMCID:: PMC3067911

Abstract Article PDF–1.7M

Select item 242548915.

An ultraconserved Hox–Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4

Xavier Lampe, Omar Abdel Samad, Allan Guiguen, Christelle Matis, Sophie Remacle, Jacques J. Picard, Filippo M. Rijli, René Rezsohazy

Nucleic Acids Res. 2008 Jun; 36(10): 3214–3225. Published online 2008 Apr 16. doi: 10.1093/nar/gkn148

PMCID:: PMC2425489

Abstract Article PDF–3.4M

Select item 495833616.

A distal 594 bp ECR specifies Hmx1 expression in pinna and lateral facial morphogenesis and is regulated by the Hox-Pbx-Meis complex

Jessica M. Rosin, Wenjie Li, Liza L. Cox, Sara M. Rolfe, Victor Latorre, Jennifer A. Akiyama, Axel Visel, Takashi Kuramoto, Nicoletta Bobola, Eric E. Turner, Timothy C. Cox

Development. 2016 Jul 15; 143(14): 2582–2592. doi: 10.1242/dev.133736

PMCID:: PMC4958336

Abstract Article

Select item 382056417.

The Homeodomain Transcription Factor Hoxa2 Interacts with and Promotes the Proteasomal Degradation of the E3 Ubiquitin Protein Ligase RCHY1

Isabelle Bergiers, Laure Bridoux, Nathan Nguyen, Jean-Claude Twizere, René Rezsöhazy

PLoS One. 2013; 8(11): e80387. Published online 2013 Nov 7. doi: 10.1371/journal.pone.0080387

PMCID:: PMC3820564

Abstract Article PDF–1.2M

Select item 294415918.

Matrix metalloproteinase-25 has a functional role in mouse secondary palate development and is a downstream target of TGF-β3

Graham D Brown, Adil J Nazarali

BMC Dev Biol. 2010; 10: 93. Published online 2010 Sep 1. doi: 10.1186/1471-213X-10-93

PMCID:: PMC2944159

Abstract Article PDF–5.7M

Select item 369039919.

linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cis

Hédia Maamar, Moran N. Cabili, John Rinn, Arjun Raj

Genes Dev. 2013 Jun 1; 27(11): 1260–1271. doi: 10.1101/gad.217018.113

PMCID:: PMC3690399

Abstract Article PDF–1.2M

Select item 644548620.

Hypomorphic mutation of the mouse Huntington’s disease gene orthologue

Vidya Murthy, Toma Tebaldi, Toshimi Yoshida, Serkan Erdin, Teresa Calzonetti, Ravi Vijayvargia, Takshashila Tripathi, Emanuela Kerschbamer, Ihn Sik Seong, Alessandro Quattrone, Michael E. Talkowski, James F. Gusella, Katia Georgopoulos, Marcy E. MacDonald, Marta Biagioli

PLoS Genet. 2019 Mar; 15(3): e1007765. Published online 2019 Mar 21. doi: 10.1371/journal.pgen.1007765