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Items: 1 to 20 of 54

1.
The multistep oxidation of cholesterol to pregnenolone by human cytochrome P450 11A1 is highly processive
Kevin D. McCarty, Lu Liu, Yasuhiro Tateishi, Hannah L. Wapshott-Stehli, F. Peter Guengerich
J Biol Chem. 2024 Jan; 300(1): 105495. Published online 2023 Nov 24. doi: 10.1016/j.jbc.2023.105495
PMCID:
PMC10716780
AbstractArticlePDF–1.3M
2.
In-Silico Investigation of Effects of Single-Nucleotide Polymorphisms in PCOS-Associated CYP11A1 Gene on Mutated Proteins
Fatima Muccee, Osama Bijou, Steve Harakeh, Rabi’atul Adawiyah, R. Z. Sayyed, Leila Haghshenas, Dikhnah Alshehri, Mohammad Javed Ansari, Shakira Ghazanfar
Genes (Basel) 2022 Jul; 13(7): 1231. Published online 2022 Jul 12. doi: 10.3390/genes13071231
PMCID:
PMC9317558
AbstractArticlePDF–7.2M
3.
The significance of CYP11A1 expression in skin physiology and pathology
RM Slominski, C Raman, C Elmets, AM Jetten, AT Slominski, RC Tuckey
Mol Cell Endocrinol. Author manuscript; available in PMC 2022 Jun 15.
Published in final edited form as: Mol Cell Endocrinol. 2021 Jun 15; 530: 111238. Published online 2021 Mar 12. doi: 10.1016/j.mce.2021.111238
PMCID:
PMC8205265
AbstractArticlePDF–1.6M
4.
Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children
Meiqin Wang, Matthew J. Strand, Bruce J. Lanser, Carah Santos, Kreso Bendelja, Jennifer Fish, Elizabeth A. Esterl, Shigeru Ashino, Jordan K. Abbott, Vijaya Knight, Erwin W. Gelfand
PLoS One. 2020; 15(6): e0233563. Published online 2020 Jun 4. doi: 10.1371/journal.pone.0233563
PMCID:
PMC7272076
AbstractArticlePDF–1.3M
5.
Characterization of the CYP11A1 Nonsynonymous Variant p.E314K in Children Presenting With Adrenal Insufficiency
Vipula Kolli, Hannah Kim, Ahmed Torky, Qizong Lao, Christina Tatsi, Ashwini Mallappa, Deborah P Merke
J Clin Endocrinol Metab. 2019 Feb; 104(2): 269–276. Published online 2018 Oct 8. doi: 10.1210/jc.2018-01661
PMCID:
PMC6607962
AbstractArticle
6.
Evidence that Compound I is the active species in both the hydroxylase and lyase steps by which P450scc converts cholesterol to pregnenolone: EPR/ENDOR/cryoreduction/annealing studies
Roman Davydov, Natallia Strushkevich, David Smil, Aliaksei Yantsevich, Andrey Gilep, Sergey Usanov, Brian M. Hoffman
Biochemistry. Author manuscript; available in PMC 2016 Dec 8.
Published in final edited form as: Biochemistry. 2015 Dec 8; 54(48): 7089–7097. Published online 2015 Nov 25. doi: 10.1021/acs.biochem.5b00903
PMCID:
PMC4732517
AbstractArticlePDF–1.6M
7.
CYP11A1 microsatellite (tttta)n polymorphism in PCOS women from South India
K. Ranjith Reddy, M. L. N. Deepika, K. Supriya, K. Prasanna Latha, S. S. Lakshmana Rao, V. Usha Rani, P. Jahan
J Assist Reprod Genet. 2014 Jul; 31(7): 857–863. Published online 2014 May 4. doi: 10.1007/s10815-014-0236-x
PMCID:
PMC4096885
AbstractArticlePDF–540K
8.
Transcriptome analysis of MENX-associated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas
Misu Lee, Ilaria Marinoni, Martin Irmler, Tsambika Psaras, Jürgen B. Honegger, Rudi Beschorner, Natasa Anastasov, Johannes Beckers, Marily Theodoropoulou, Federico Roncaroli, Natalia S. Pellegata
Acta Neuropathol. 2013; 126(1): 137–150. Published online 2013 Jun 12. doi: 10.1007/s00401-013-1132-7
PMCID:
PMC3690182
AbstractArticlePDF–1.3M
9.
Abnormal Apoptosis of Trophoblastic Cells Is Related to the Up-Regulation of CYP11A Gene in Placenta of Preeclampsia Patients
Guolin He, Wenming Xu, Yan Chen, Xinghui Liu, Mingrong Xi
PLoS One. 2013; 8(3): e59609. Published online 2013 Mar 29. doi: 10.1371/journal.pone.0059609
PMCID:
PMC3612086
AbstractArticlePDF–4.2M
10.
Varied Clinical Presentations of Seven Patients With Mutations in CYP11A1 Encoding the Cholesterol Side-Chain Cleavage Enzyme, P450scc
Meng Kian Tee, Michal Abramsohn, Neta Loewenthal, Mark Harris, Sudeep Siwach, Ana Kaplinsky, Barak Markus, Ohad Birk, Val C. Sheffield, Ruti Pavari, Eli Hershkovitz, Walter L. Miller
J Clin Endocrinol Metab. 2013 Feb; 98(2): 713–720. Published online 2013 Jan 21. doi: 10.1210/jc.2012-2828
Correction in:
J Clin Endocrinol Metab. 2013 Oct; 98(10): 4213.
PMCID:
PMC3565115
AbstractArticle
11.
No Association Between the Microsatellite Polymorphism (TTTTA)n in the Promoter of the CYP11A Gene and Ovarian Hyperstimulation Syndrome
Polonca Ferk, Ksenija Gersak, Natasa Teran
J Assist Reprod Genet. 2006 Jan; 23(1): 29–32. Published online 2006 Jan 4. doi: 10.1007/s10815-005-9009-x
PMCID:
PMC3455435
AbstractArticlePDF–180K
12.
Risk-Association of CYP11A1 Polymorphisms and Breast Cancer Among Han Chinese Women in Southern China
Minying Sun, Xuexi Yang, Changsheng Ye, Weiwen Xu, Guangyu Yao, Jun Chen, Ming Li
Int J Mol Sci. 2012; 13(4): 4896–4905. Published online 2012 Apr 18. doi: 10.3390/ijms13044896
PMCID:
PMC3344254
AbstractArticlePDF–183K
13.
Partial Defect in the Cholesterol Side-Chain Cleavage Enzyme P450scc (CYP11A1) Resembling Nonclassic Congenital Lipoid Adrenal Hyperplasia
Taninee Sahakitrungruang, Meng Kian Tee, Piers R. Blackett, Walter L. Miller
J Clin Endocrinol Metab. 2011 Mar; 96(3): 792–798. Published online 2010 Dec 15. doi: 10.1210/jc.2010-1828
PMCID:
PMC3047228
AbstractArticle
14.
20-Hydroxyvitamin D3, a Product of Vitamin D3 Hydroxylation by Cytochrome P450scc, Stimulates Keratinocyte Differentiation
Blazej Zbytek, Zorica Janjetovic, Robert C. Tuckey, Michal A. Zmijewski, Trevor W. Sweatman, Emily Jones, Minh N. Nguyen, Andrzej T. Slominski
J Invest Dermatol. Author manuscript; available in PMC 2009 Sep 1.
Published in final edited form as: J Invest Dermatol. 2008 Sep; 128(9): 2271–2280. Published online 2008 Mar 27. doi: 10.1038/jid.2008.62
PMCID:
PMC2574837
AbstractArticlePDF–904K
15.
Regulated expression of cytochrome P-450scc (cholesterol-side-chain cleavage enzyme) in cultured cell lines detected by antibody against bacterially expressed human protein.
M C Hu, I C Guo, J H Lin, B C Chung
Biochem J. 1991 Mar 15; 274(Pt 3): 813–817. doi: 10.1042/bj2740813
PMCID:
PMC1149983
SummaryPage BrowsePDF–1.0M
16.
Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta.
B C Chung, K J Matteson, R Voutilainen, T K Mohandas, W L Miller
Proc Natl Acad Sci U S A. 1986 Dec; 83(23): 8962–8966. doi: 10.1073/pnas.83.23.8962
PMCID:
PMC387054
SummaryPage BrowsePDF–1.2M
17.
Helicobacter pylori promotes gastric cancer through CagA-mediated mitochondrial cholesterol accumulation by targeting CYP11A1 redistribution
Zhijun Zhang, Hongxin Huang, Zetian Chen, Mengpei Yan, Chen Lu, Zekuan Xu, Zheng Li
Int J Biol Sci. 2024; 20(10): 4007–4028. Published online 2024 Jul 15. doi: 10.7150/ijbs.96425
PMCID:
PMC11302876
AbstractArticlePDF–9.9M
18.
CYP3A4 and CYP11A1 variants are risk factors for ischemic stroke: a case control study
Ning Gao, Hong Tang, Ling Gao, Guolong Tu, Han Luo, Ying Xia
BMC Neurol. 2020; 20: 77. Published online 2020 Mar 4. doi: 10.1186/s12883-020-1628-4
PMCID:
PMC7055027
AbstractArticlePDF–631K
19.
Active site structures of CYP11A1 in the presence of its physiological substrates and alterations upon binding of Adrenodoxin
Qianhong Zhu, Piotr J. Mak, Robert C. Tuckey, James R. Kincaid
Biochemistry. Author manuscript; available in PMC 2019 May 30.
Published in final edited form as: Biochemistry. 2017 Oct 31; 56(43): 5786–5797. Published online 2017 Oct 20. doi: 10.1021/acs.biochem.7b00766
PMCID:
PMC6541926
AbstractArticlePDF–864K
20.
Lumisterol is metabolized by CYP11A1: discovery of a new pathway
Robert C. Tuckey, Andrzej T. Slominski, Chloe Y. S. Cheng, Jianjun Chen, Tae-Kang Kim, Min Xiao, Wei Li
Int J Biochem Cell Biol. Author manuscript; available in PMC 2015 Oct 1.
Published in final edited form as: Int J Biochem Cell Biol. 2014 Oct; 55: 24–34. Published online 2014 Aug 13. doi: 10.1016/j.biocel.2014.08.004
PMCID:
PMC4252613
AbstractArticlePDF–2.4M

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