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Select item 105648411.

Disabled-2: a protein up-regulated by high molecular weight hyaluronan has both tumor promoting and tumor suppressor roles in ovarian cancer

Zoe K. Price, Noor A. Lokman, Mai Sugiyama, Yoshihiro Koya, Masato Yoshihara, Martin K. Oehler, Hiroaki Kajiyama, Carmela Ricciardelli

Cell Mol Life Sci. 2023 Nov; 80(11): 320. Published online 2023 Oct 10. doi: 10.1007/s00018-023-04972-9

PMCID:: PMC10564841

Abstract Article PDF–2.3M

Select item 102904522.

Genetic polymorphism of the Dab2 gene and its association with Type 2 Diabetes Mellitus in the Chinese Uyghur population

Yan-Peng Li, Dilare Adi, Ying-Hong Wang, Yong-Tao Wang, Xiao-Lei Li, Zhen-Yan Fu, Fen Liu, Aibibanmu Aizezi, Jialin Abuzhalihan, Min-Tao Gai, Xiang Ma, Xiao-mei Li, Xiang Xie, Yi-Tong Ma

PeerJ. 2023; 11: e15536. Published online 2023 Jun 21. doi: 10.7717/peerj.15536

PMCID:: PMC10290452

Abstract Article PDF–1.0M

Select item 98210693.

Disabled-2 (DAB2): A Key Regulator of Anti- and Pro-Tumorigenic Pathways

Zoe K. Price, Noor A. Lokman, Masato Yoshihara, Hiroaki Kajiyama, Martin K. Oehler, Carmela Ricciardelli

Int J Mol Sci. 2023 Jan; 24(1): 696. Published online 2022 Dec 31. doi: 10.3390/ijms24010696

PMCID:: PMC9821069

Abstract Article PDF–725K

Select item 73374494.

Dab2 gene variant is associated with increased coronary artery disease risk in Chinese Han population

Yinghong Wang, Yongtao Wang, Dilare Adi, XiaoDong He, Fen Liu, Asiya Abudesimu, Zhenyan Fu, Yitong Ma

Medicine (Baltimore) 2020 Jul 2; 99(27): e20924. Published online 2020 Jul 2. doi: 10.1097/MD.0000000000020924

PMCID:: PMC7337449

Abstract Article PDF–231K

Select item 65252415.

Loss of Disabled-2 Expression in Pancreatic Cancer Progression

Barbara A. Hocevar

Sci Rep. 2019; 9: 7532. Published online 2019 May 17. doi: 10.1038/s41598-019-43992-z

PMCID:: PMC6525241

Abstract Article PDF–2.0M

Select item 53420706.

Low disabled-2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma

Wen-Lun Wang, Wei-Lun Chang, Hsiao-Bai Yang, Yu-Chi Wang, I-Wei Chang, Ching-Tai Lee, Chi-Yang Chang, Jaw-Town Lin, Bor-Shyang Sheu

Oncotarget. 2016 Nov 1; 7(44): 71169–71181. Published online 2016 Mar 29. doi: 10.18632/oncotarget.8460

PMCID:: PMC5342070

Abstract Article PDF–7.7M

Select item 41244157.

Loss of disabled-2 expression is an early event in esophageal squamous tumorigenesis

Kumar Anupam, Chatopadhyay Tusharkant, Siddhartha Datta Gupta, Ralhan Ranju

World J Gastroenterol. 2006 Oct 7; 12(37): 6041–6045. Published online 2006 Oct 7. doi: 10.3748/wjg.v12.i37.6041

PMCID:: PMC4124415

Abstract Article PDF–801K

Select item 40194938.

Dab2 inhibits the cholesterol-dependent activation of JNK by TGF-β

Keren E. Shapira, Tal Hirschhorn, Lior Barzilay, Nechama I. Smorodinsky, Yoav I. Henis, Marcelo Ehrlich

Mol Biol Cell. 2014 May 15; 25(10): 1620–1628. doi: 10.1091/mbc.E13-09-0537

PMCID:: PMC4019493

Abstract Article PDF–1.5M

Select item 34880459.

Structure, Sulfatide Binding Properties, and Inhibition of Platelet Aggregation by a Disabled-2 Protein-derived Peptide

Shuyan Xiao, John J. Charonko, Xiangping Fu, Alireza Salmanzadeh, Rafael V. Davalos, Pavlos P. Vlachos, Carla V. Finkielstein, Daniel G. S. Capelluto

J Biol Chem. 2012 Nov 2; 287(45): 37691–37702. Published online 2012 Sep 13. doi: 10.1074/jbc.M112.385609

PMCID:: PMC3488045

Abstract Article PDF–2.1M

Select item 303765210.

Negative Regulation of the Endocytic Adaptor Disabled-2 (Dab2) in Mitosis

David Chetrit, Lior Barzilay, Galit Horn, Tom Bielik, Nechama I. Smorodinsky, Marcelo Ehrlich

J Biol Chem. 2011 Feb 18; 286(7): 5392–5403. Published online 2010 Nov 19. doi: 10.1074/jbc.M110.161851

PMCID:: PMC3037652

Abstract Article PDF–4.7M

Select item 299423311.

Disabled-2 downregulation promotes epithelial-to-mesenchymal transition

J C Martin, B-S Herbert, B A Hocevar

Br J Cancer. 2010 Nov; 103(11): 1716–1723. Published online 2010 Nov 9. doi: 10.1038/sj.bjc.6605975

PMCID:: PMC2994233

Abstract Article PDF–540K

Select item 289163812.

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

Joanna H Tong, David C Ng, Shuk L Chau, Ken K So, Patrick P Leung, Tin L Lee, Raymond W Lung, Michael W Chan, Anthony W Chan, Kwok W Lo, Ka F To

BMC Cancer. 2010; 10: 253. Published online 2010 Jun 3. doi: 10.1186/1471-2407-10-253

PMCID:: PMC2891638

Abstract Article PDF–1.1M

Select item 277813213.

Sulfatides Partition Disabled-2 in Response to Platelet Activation

Karen E. Drahos, John D. Welsh, Carla V. Finkielstein, Daniel G. S. Capelluto

PLoS One. 2009; 4(11): e8007. Published online 2009 Nov 24. doi: 10.1371/journal.pone.0008007

PMCID:: PMC2778132

Abstract Article PDF–861K

Select item 844854714.

MicroRNA-93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2

Jiwei Huang, Ruozhi Xiao, Xiaozhen Wang, Bijay Khadka, Zhigang Fang, Mingxue Yu, Ling Zhang, Jieying Wu, Jiajun Liu

Int J Oncol. 2021 Oct; 59(4): 81. Published online 2021 Sep 2. doi: 10.3892/ijo.2021.5260

PMCID:: PMC8448547

Abstract Article PDF–7.7M

Select item 811385715.

A dynamic Dab2 keeps myosin VI stably on track

Joseph A. Cirilo, Jr., Christopher M. Yengo

J Biol Chem. 2021 Jan-Jun; 296: 100640. Published online 2021 May 3. doi: 10.1016/j.jbc.2021.100640

PMCID:: PMC8113857

Abstract Article PDF–243K

Select item 794859316.

Dynamic multimerization of Dab2–Myosin VI complexes regulates cargo processivity while minimizing cortical actin reorganization

Ashim Rai, Duha Vang, Michael Ritt, Sivaraj Sivaramakrishnan

J Biol Chem. 2021 Jan-Jun; 296: 100232. Published online 2021 Jan 7. doi: 10.1074/jbc.RA120.012703

PMCID:: PMC7948593

Abstract Article PDF–2.8M

Select item 482992317.

Abundance of megalin and Dab2 is reduced in syncytiotrophoblast during placental malaria, which may contribute to low birth weight

Jared Lybbert, Justin Gullingsrud, Olga Chesnokov, Eleanor Turyakira, Mehul Dhorda, Philippe J. Guerin, Patrice Piola, Atis Muehlenbachs, Andrew V. Oleinikov

Sci Rep. 2016; 6: 24508. Published online 2016 Apr 13. doi: 10.1038/srep24508

PMCID:: PMC4829923

Abstract Article PDF–969K

Select item 481111318.

Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammation

Samantha E. Adamson, Rachael Griffiths, Radim Moravec, Subramanian Senthivinayagam, Garren Montgomery, Wenshu Chen, Jenny Han, Poonam R. Sharma, Garrett R. Mullins, Stacey A. Gorski, Jonathan A. Cooper, Alexandra Kadl, Kyle Enfield, Thomas J. Braciale, Thurl E. Harris, Norbert Leitinger

J Clin Invest. 2016 Apr 1; 126(4): 1311–1322. Published online 2016 Feb 29. doi: 10.1172/JCI79590