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Items: 1 to 20 of 314

1.
Interleukin 2 regulation following semi-allogeneic bone marrow transplantation in mice
Ali Abdul-Hai, Arie Ben-Yehuda, Haya Galsky, Shimon Slavin, Reuven Or
Cancer Immunol Immunother. 2006 Nov; 55(11): 1330–1336. Published online 2006 Feb 1. doi: 10.1007/s00262-006-0125-y
PMCID:
PMC11030658
AbstractArticlePDF–314K
2.
Dopaminergic Signalling Enhances IL-2 Production and Strengthens Anti-Tumour Response Exerted by Cytotoxic T Lymphocytes in a Melanoma Mouse Model
Ornella Chovar-Vera, Ernesto López, Felipe Gálvez-Cancino, Carolina Prado, Dafne Franz, Diego A. Figueroa, Alexandra Espinoza, Claudio Figueroa, Alvaro Lladser, Rodrigo Pacheco
Cells. 2022 Nov; 11(22): 3536. Published online 2022 Nov 9. doi: 10.3390/cells11223536
PMCID:
PMC9688276
AbstractArticlePDF–1.7M
3.
Diversity-Oriented Synthesis of a Molecular Library of Immunomodulatory α-Galactosylceramides with Fluorous-Tag-Assisted Purification and Evaluation of Their Bioactivities in Regard to IL-2 Secretion
Yeng-Nan Chen, Jung-Tung Hung, Fan-Dan Jan, Yung-Yu Su, Jih-Ru Hwu, Alice L. Yu, Avijit K. Adak, Chun-Cheng Lin
Int J Mol Sci. 2022 Nov; 23(21): 13403. Published online 2022 Nov 2. doi: 10.3390/ijms232113403
PMCID:
PMC9659121
AbstractArticlePDF–4.1M
4.
The antitumor effect induced by an IL-2 ‘no-alpha’ mutein depends on changes in the CD8+ T lymphocyte/Treg cell balance
Tania Carmenate, Galia Montalvo, Sum Lai Lozada, Yaretnis Rodriguez, Yaquelin Ortiz, Claudia Díaz, Janet Avellanet, Juhee Kim, Charles D. Surh, Luis Graça, Kalet León
Front Immunol. 2022; 13: 974188. Published online 2022 Aug 17. doi: 10.3389/fimmu.2022.974188
PMCID:
PMC9428827
AbstractArticlePDF–1.2M
5.
Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
Carly E. Whyte, Kailash Singh, Oliver T. Burton, Meryem Aloulou, Lubna Kouser, Rafael Valente Veiga, Amy Dashwood, Hanneke Okkenhaug, Samira Benadda, Alena Moudra, Orian Bricard, Stephanie Lienart, Pascal Bielefeld, Carlos P. Roca, Francisco José Naranjo-Galindo, Félix Lombard-Vadnais, Steffie Junius, David Bending, Masahiro Ono, Tino Hochepied, Timotheus Y.F. Halim, Susan Schlenner, Sylvie Lesage, James Dooley, Adrian Liston
J Exp Med. 2022 Jul 4; 219(7): e20212391. Published online 2022 Jun 14. doi: 10.1084/jem.20212391
Correction in:
J Exp Med. 2022 Aug 1; 219(8): jem.2021149805312022c.
PMCID:
PMC9202720
AbstractArticlePDF–9.2M
6.
The Blockade of Interleukin-2 During the Acute Phase of Trypanosoma cruzi Infection Reveals Its Dominant Regulatory Role
Jorge Nihei, Fabiola Cardillo, Jose Mengel
Front Cell Infect Microbiol. 2021; 11: 758273. Published online 2021 Nov 17. doi: 10.3389/fcimb.2021.758273
PMCID:
PMC8635756
AbstractArticlePDF–3.5M
7.
Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance
Toshihito Hirai, Teresa L. Ramos, Po-Yu Lin, Federico Simonetta, Leon L. Su, Lora K. Picton, Jeanette Baker, Jian-Xin Lin, Peng Li, Kinya Seo, Juliane K. Lohmeyer, Sara Bolivar-Wagers, Melissa Mavers, Warren J. Leonard, Bruce R. Blazar, K. Christopher Garcia, Robert S. Negrin
J Clin Invest. 2021 Apr 15; 131(8): e139991. Published online 2021 Apr 15. doi: 10.1172/JCI139991
PMCID:
PMC8059880
AbstractArticlePDF–6.5M
8.
Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch
Viviane S. De Paula, Kevin M. Jude, Santrupti Nerli, Caleb R. Glassman, K. Christopher Garcia, Nikolaos G. Sgourakis
Proc Natl Acad Sci U S A. 2020 Mar 31; 117(13): 7183–7192. Published online 2020 Mar 17. doi: 10.1073/pnas.2000419117
PMCID:
PMC7132253
AbstractArticlePDF–2.1M
9.
IL-2 Therapy Diminishes Renal Inflammation and the Activity of Kidney-Infiltrating CD4+ T Cells in Murine Lupus Nephritis
Angelika Rose, Caroline von Spee-Mayer, Lutz Kloke, Kaiyin Wu, Anja Kühl, Philipp Enghard, Gerd-Rüdiger Burmester, Gabriela Riemekasten, Jens Y. Humrich
Cells. 2019 Oct; 8(10): 1234. Published online 2019 Oct 11. doi: 10.3390/cells8101234
PMCID:
PMC6829607
AbstractArticlePDF–1.5M
10.
IL-2 Restores T-Cell Dysfunction Induced by Persistent Mycobacterium tuberculosis Antigen Stimulation
Xun Liu, Fei Li, Hongxia Niu, Lan Ma, Jianzhu Chen, Ying Zhang, Liang Peng, Chao Gan, Xingming Ma, Bingdong Zhu
Front Immunol. 2019; 10: 2350. Published online 2019 Oct 2. doi: 10.3389/fimmu.2019.02350
Correction in:
Front Immunol. 2020; 11: 1671.
PMCID:
PMC6783502
AbstractArticlePDF–1.4M
11.
IL-2 modulates the TCR signaling threshold for CD8 but not CD4 T cell proliferation on a single cell level
Byron Au-Yeung, Geoffrey Alexander Smith, James L. Mueller, Cheryl S. Heyn, Rebecca Garrett Jaszczak, Arthur Weiss, Julie Zikherman
J Immunol. Author manuscript; available in PMC 2018 Mar 15.
Published in final edited form as: J Immunol. 2017 Mar 15; 198(6): 2445–2456. Published online 2017 Feb 3. doi: 10.4049/jimmunol.1601453
PMCID:
PMC5340617
AbstractArticlePDF–3.3M
12.
Long-Range Transcriptional Control of the Il2 Gene by an Intergenic Enhancer
Parul Mehra, Andrew D. Wells
Mol Cell Biol. 2015 Nov; 35(22): 3880–3891. Prepublished online 2015 Sep 8. Published online 2015 Oct 16. doi: 10.1128/MCB.00592-15
PMCID:
PMC4609740
AbstractArticlePDF–1.8M
13.
Destabilization of peptide: MHC interaction induces IL-2 resistant anergy in diabetogenic T cells
Lindsay J. Edwards, Brian D. Evavold
J Autoimmun. Author manuscript; available in PMC 2015 Jun 13.
Published in final edited form as: J Autoimmun. 2013 Aug; 44: 82–90. Published online 2013 Jul 26. doi: 10.1016/j.jaut.2013.07.002
PMCID:
PMC4465239
AbstractArticlePDF–1.8M
14.
Interleukin-2 Protects Lupus-prone Mice from Multiple End-organ Damage by Limiting CD4−CD8− Interleukin-17-producing T-cells
Masayuki Mizui, Tomohiro Koga, Linda A. Lieberman, Jessica Beltran, Nobuya Yoshida, Mark C. Johnson, Roland Tisch, George C. Tsokos
J Immunol. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: J Immunol. 2014 Sep 1; 193(5): 2168–2177. Published online 2014 Jul 25. doi: 10.4049/jimmunol.1400977
PMCID:
PMC4135016
AbstractArticlePDF–645K
15.
Identification of a Cytotoxic Form of Dimeric Interleukin-2 in Murine Tissues
Lucile E. Wrenshall, Suzanne E. Clabaugh, David R. Cool, Prakash Arumugam, William C. Grunwald, Deandra R. Smith, Gino C. Liu, John D. Miller
PLoS One. 2014; 9(7): e102191. Published online 2014 Jul 14. doi: 10.1371/journal.pone.0102191
PMCID:
PMC4097599
AbstractArticlePDF–2.7M
16.
Immunogenic, but Not Steady-State, Antigen Presentation Permits Regulatory T-Cells To Control CD8+ T-Cell Effector Differentiation by IL-2 Modulation
Alice McNally, Michael McNally, Ryan Galea, Ranjeny Thomas, Raymond J. Steptoe
PLoS One. 2014; 9(1): e85455. Published online 2014 Jan 13. doi: 10.1371/journal.pone.0085455
PMCID:
PMC3890313
AbstractArticlePDF–904K
17.
IL-2 Immunotherapy Reveals Potential for Innate Beta Cell Regeneration in the Non-Obese Diabetic Mouse Model of Autoimmune Diabetes
Yaiza Diaz-de-Durana, Janet Lau, Deborah Knee, Christophe Filippi, Marco Londei, Peter McNamara, Marc Nasoff, Michael DiDonato, Richard Glynne, Ann E. Herman
PLoS One. 2013; 8(10): e78483. Published online 2013 Oct 24. doi: 10.1371/journal.pone.0078483
PMCID:
PMC3813455
AbstractArticlePDF–3.1M
18.
Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62LLOFoxP3+CD4+ T cells with limited suppressor activity
Kevin S. Goudy, Mark C. Johnson, Alaina Garland, Chengwen Li, Richard J. Samulski, Bo Wang, Roland Tisch
Eur J Immunol. Author manuscript; available in PMC 2013 Oct 22.
Published in final edited form as: Eur J Immunol. 2011 May; 41(5): 1480–1490. Published online 2011 Apr 20. doi: 10.1002/eji.201040890
PMCID:
PMC3805504
AbstractArticlePDF–2.2M
19.
IL-2/Anti-IL-2 Complex Attenuates Renal Ischemia-Reperfusion Injury through Expansion of Regulatory T Cells
Myung-Gyu Kim, Tai Yeon Koo, Ji-Jing Yan, Eunwon Lee, Kyu Hyun Han, Jong Cheol Jeong, Han Ro, Beom Seok Kim, Sang-Kyung Jo, Kook Hwan Oh, Charles D. Surh, Curie Ahn, Jaeseok Yang
J Am Soc Nephrol. 2013 Oct; 24(10): 1529–1536. Published online 2013 Jul 5. doi: 10.1681/ASN.2012080784
PMCID:
PMC3785269
AbstractArticle
20.
Differential targeting of IL-2 and T cell receptor signaling pathways selectively expands regulatory T cells while inhibiting conventional T cells
Atsushi Satake, Amanda M Schmidt, Angela Archambault, Theresa M Leichner, Gregory F Wu, Taku Kambayashi
J Autoimmun. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: J Autoimmun. 2013 Aug; 44: 13–20. Published online 2013 Jul 5. doi: 10.1016/j.jaut.2013.06.009
PMCID:
PMC3752416
AbstractArticlePDF–1.5M

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