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Select item 111336341.

IL-2Rα KO mice exhibit maternal microchimerism and reveal nuclear localization of IL-2Rα in lymphoid and non-lymphoid cells

Victoria A. Wong, Kristie N. Dinh, Guangchun Chen, Lucile E. Wrenshall

Front Immunol. 2024; 15: 1369818. Published online 2024 May 15. doi: 10.3389/fimmu.2024.1369818

PMCID:: PMC11133634

Abstract Article PDF–2.6M

Select item 108325122.

Distinct use of super-enhancer elements controls cell-type specific CD25 transcription and function

Rosanne Spolski, Peng Li, Vivek Chandra, Boyoung Shin, Shubham Goel, Keiko Sakamoto, Chengyu Liu, Jangsuk Oh, Min Ren, Yutaka Enomoto, Erin E. West, Stephen M. Christensen, Edwin C.K. Wan, Meili Ge, Jian-Xin Lin, Bingyu Yan, Majid Kazemian, Zu-Xi Yu, Keisuke Nagao, Pandurangan Vijayanand, Ellen V. Rothenberg, Warren J. Leonard

Sci Immunol. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Sci Immunol. 2023 Nov 3; 8(89): eadi8217. Published online 2023 Nov 3. doi: 10.1126/sciimmunol.adi8217

PMCID:: PMC10832512

Abstract Article PDF–2.6M

Select item 102475073.

CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated

Michael C. Jones, Catherine Castonguay, Padma P. Nanaware, Grant C. Weaver, Brian Stadinski, Olivia A. Kugler-Umana, Eric S. Huseby, Lawrence J. Stern, Karl Kai McKinstry, Tara M. Strutt, Priyadharshini Devarajan, Susan L. Swain

J Immunol. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: J Immunol. 2023 Jun 15; 210(12): 1950–1961. doi: 10.4049/jimmunol.2200337

PMCID:: PMC10247507

Abstract Article PDF–2.5M

Select item 80270014.

Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool

Marc Permanyer, Berislav Bošnjak, Silke Glage, Michaela Friedrichsen, Stefan Floess, Jochen Huehn, Gwendolyn E. Patzer, Ivan Odak, Nadine Eckert, Razieh Zargari, Laura Ospina-Quintero, Hristo Georgiev, Reinhold Förster

Cell Mol Immunol. 2021 Feb; 18(2): 398–414. Published online 2021 Jan 6. doi: 10.1038/s41423-020-00599-z

PMCID:: PMC8027001

Abstract Article PDF–5.7M

Select item 77385275.

T cell signaling and Treg dysfunction correlate to disease kinetics in IL-2Rα-KO autoimmune mice

Genevieve N. Mullins, Kristen M. Valentine, Mufadhal Al-Kuhlani, Dan Davini, Kirk D. C. Jensen, Katrina K. Hoyer

Sci Rep. 2020; 10: 21994. Published online 2020 Dec 15. doi: 10.1038/s41598-020-78975-y

PMCID:: PMC7738527

Abstract Article PDF–6.2M

Select item 70150626.

Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1

Qi Yin, Hongye Wang, Na Li, Yifu Ding, Zhenfei Xie, Lifang Jin, Yan Li, Qiong Wang, Xinyi Liu, Liuqing Xu, Qing Li, Yongjian Ma, Yanbo Cheng, Kai Wang, Cuiqing Zhong, Qian Yu, Wei Tang, Wanjin Chen, Wenjun Yang, Fan Zhang, Chen Ding, Lan Bao, Bin Zhou, Ping Hu, Jinsong Li

Cell Res. 2020 Feb; 30(2): 133–145. Published online 2019 Dec 18. doi: 10.1038/s41422-019-0264-2

PMCID:: PMC7015062

Abstract Article PDF–5.5M

Select item 67252507.

Subthalamic Neurons Coordinate Basal Ganglia Function through Differential Neural Pathways

Yasunobu Yasoshima, Nobuyuki Kai, Shigetaka Yoshida, Sadao Shiosaka, Yoshimasa Koyama, Yukihiko Kayama, Kazuto Kobayashi

J Neurosci. 2005 Aug 24; 25(34): 7743–7753. doi: 10.1523/JNEUROSCI.1904-05.2005

PMCID:: PMC6725250

Abstract Article PDF–888K

Select item 56757168.

Discovery of stimulation-responsive immune enhancers with CRISPR activation

Dimitre R. Simeonov, Benjamin G. Gowen, Mandy Boontanrart, Theodore L. Roth, John D. Gagnon, Maxwell R. Mumbach, Ansuman T. Satpathy, Youjin Lee, Nicolas L. Bray, Alice Y. Chan, Dmytro S. Lituiev, Michelle L. Nguyen, Rachel E. Gate, Meena Subramaniam, Zhongmei Li, Jonathan M. Woo, Therese Mitros, Graham J. Ray, Gemma L. Curie, Nicki Naddaf, Julia S. Chu, Hong Ma, Eric Boyer, Frederic Van Gool, Hailiang Huang, Ruize Liu, Victoria R. Tobin, Kathrin Schumann, Mark J. Daly, Kyle K Farh, K. Mark Ansel, Chun J. Ye, William J. Greenleaf, Mark S. Anderson, Jeffrey A. Bluestone, Howard Y. Chang, Jacob E. Corn, Alexander Marson

Nature. Author manuscript; available in PMC 2017 Nov 7.

Published in final edited form as: Nature. 2017 Sep 7; 549(7670): 111–115. Published online 2017 Aug 30. doi: 10.1038/nature23875

Correction in:: Nature. 2018 Jun 13

PMCID:: PMC5675716

Abstract Article PDF–5.1M

Select item 49367309.

Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?

Arnold H. Zea, Tyrus Stewart, Jeannine Ascani, David J. Tate, Beatriz Finkel-Jimenez, Anna Wilk, Krzysztof Reiss, William E. Smoyer, Diego H. Aviles

PLoS One. 2016; 11(7): e0157907. Published online 2016 Jul 7. doi: 10.1371/journal.pone.0157907

PMCID:: PMC4936730

Abstract Article PDF–2.3M

Select item 340914510.

CD4⁺CD25⁺ Regulatory T Cell Depletion Modulates Anxiety and Depression-Like Behaviors in Mice

Soo-Jeong Kim, Hyojung Lee, Gihyun Lee, Sei-Joong Oh, Min-Kyu Shin, Insop Shim, Hyunsu Bae

PLoS One. 2012; 7(7): e42054. Published online 2012 Jul 31. doi: 10.1371/journal.pone.0042054

PMCID:: PMC3409145

Abstract Article PDF–802K

Select item 335858611.

Role of CD25⁺ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis (EAU)

Dongchun Liang, Aijun Zuo, Hui Shao, Willi K. Born, Rebecca L. O'Brien, Henry J. Kaplan, Deming Sun

J Immunol. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: J Immunol. 2012 Jun 1; 188(11): 5785–5791. Published online 2012 Apr 25. doi: 10.4049/jimmunol.1200109

PMCID:: PMC3358586

Abstract Article PDF–3.9M

Select item 322067412.

Partial Depletion of Natural CD4⁺CD25⁺ Regulatory T Cells with Anti-CD25 Antibody Does Not Alter the Course of Acute Influenza A Virus Infection

Richard J. Betts, Adrian W. S. Ho, David M. Kemeny

PLoS One. 2011; 6(11): e27849. Published online 2011 Nov 18. doi: 10.1371/journal.pone.0027849

PMCID:: PMC3220674

Abstract Article PDF–577K

Select item 312848513.

Depletion of CD25⁺ T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma

Weiqing Jing, Xiaocai Yan, William H. D. Hallett, Jill A. Gershan, Bryon D. Johnson

Blood. 2011 Jun 23; 117(25): 6952–6962. Prepublished online 2011 Apr 26. doi: 10.1182/blood-2010-12-326108

PMCID:: PMC3128485

Abstract Article

Select item 291335914.

Spontaneous Autoimmune Dacryoadenitis in Aged CD25KO Mice

Ehsan Rahimy, John D. Pitcher, III, Solherny B. Pangelinan, Wei Chen, William J. Farley, Jerry Y. Niederkorn, Michael E. Stern, De-Quan Li, Stephen C. Pflugfelder, Cintia S. De Paiva

Am J Pathol. 2010 Aug; 177(2): 744–753. doi: 10.2353/ajpath.2010.091116

PMCID:: PMC2913359

Abstract Article PDF–944K

Select item 275350215.

CD25⁺ T cells induce H. pylori-specific CD25^- T cell anergy but are not required to maintain persistent hyporesponsiveness

Kathleen A. Stuller, Hua Ding, Raymond W. Redline, Steven J. Czinn, Thomas G. Blanchard

Eur J Immunol. Author manuscript; available in PMC 2009 Sep 28.

Published in final edited form as: Eur J Immunol. 2008 Dec; 38(12): 3426–3435. doi: 10.1002/eji.200838428

PMCID:: PMC2753502

Abstract Article PDF–354K

Select item 185036016.

Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

Rebecca S. Keller, Shaw-Yung Shai, Christopher J. Babbitt, Can G. Pham, R. John Solaro, Maria L. Valencik, Joseph C. Loftus, Robert S. Ross

Am J Pathol. 2001 Mar; 158(3): 1079–1090. doi: 10.1016/S0002-9440(10)64055-2

PMCID:: PMC1850360

Abstract Article PDF–930K

Select item 34109217.

Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence.

A Shimuzu, S Kondo, S Takeda, J Yodoi, N Ishida, H Sabe, H Osawa, T Diamantstein, T Nikaido, T Honjo

Nucleic Acids Res. 1985 Mar 11; 13(5): 1505–1516. doi: 10.1093/nar/13.5.1505

PMCID:: PMC341092

Summary Page Browse PDF–1.3M

Select item 12607418.

The basis for TCR-mediated regulation of the IL-2 receptor α chain gene: role of widely separated regulatory elements

Hyoung-Pyo Kim, Warren J. Leonard

EMBO J. 2002 Jun 17; 21(12): 3051–3059. doi: 10.1093/emboj/cdf321

PMCID:: PMC126074

Abstract Article PDF–462K

Select item 11383719.

Control of IL-2Rα gene expression: structural changes within the proximal enhancer/core promoter during T-cell development

Jung-Hua Yeh, Salvatore Spicuglia, Sanjeex Kumar, Albert Sanchez-Sevilla, Pierre Ferrier, Jean Imbert

Nucleic Acids Res. 2002 May 1; 30(9): 1944–1951. doi: 10.1093/nar/30.9.1944

Correction in:: Nucleic Acids Res. 2002 Aug 15; 30(16): 3642.

PMCID:: PMC113837

Abstract Article PDF–365K

Select item 912757820.

The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo

Sophia Kirschke, Ireti Ogunsulire, Balachandar Selvakumar, Neele Schumacher, Tanya Sezin, Stefan Rose-John, Alexander Scheffold, Christoph Garbers, Juliane Lokau

J Biol Chem. 2022 Jun; 298(6): 101910. Published online 2022 Apr 7. doi: 10.1016/j.jbc.2022.101910

PMCID:: PMC9127578

Abstract Article PDF–1.3M

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