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Select item 82780721.

Immunoproteasome impairment via β5i/LMP7‐deletion leads to sustained pancreatic injury from experimental pancreatitis

Laura L. de Freitas Chama, Frédéric Ebstein, Birthe Wiesrecker, Preshit R. Wagh, Elke Hammer, Frank U. Weiss, Heike Junker, Maja Studencka‐Turski, Markus M. Lerch, Elke Krüger, Matthias Sendler

J Cell Mol Med. 2021 Jul; 25(14): 6786–6799. Published online 2021 Jun 15. doi: 10.1111/jcmm.16682

PMCID:: PMC8278072

Abstract Article PDF–3.4M

Select item 26926862.

Assessing the role of immuno-proteasomes in a mouse model of familial ALS

Krishna Puttaparthi, Luc Van Kaer, Jeffrey L. Elliott

Exp Neurol. Author manuscript; available in PMC 2009 Jun 8.

Published in final edited form as: Exp Neurol. 2007 Jul; 206(1): 53–58. Published online 2007 Mar 30. doi: 10.1016/j.expneurol.2007.03.024

PMCID:: PMC2692686

Abstract Article PDF–759K

Select item 26146073.

Ischemic preconditioning-induced cardioprotection is lost in mice with immunoproteasome subunit low molecular mass polypeptide-2 deficiency

Zheqing P. Cai, Zhenyun Shen, Luc Van Kaer, Lewis C. Becker

FASEB J. 2008 Dec; 22(12): 4248–4257. doi: 10.1096/fj.08-105940

PMCID:: PMC2614607

Abstract Article

Select item 21753884.

Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency

Ricardo F. Frausto, Stephen J. Crocker, Boreth Eam, Jason K. Whitmire, J L. Whitton

J Neuroimmunol. Author manuscript; available in PMC 2008 Dec 1.

Published in final edited form as: J Neuroimmunol. 2007 Dec; 192(1-2): 124–133. Published online 2007 Oct 26. doi: 10.1016/j.jneuroim.2007.09.024

PMCID:: PMC2175388

Abstract Article PDF–1.2M

Select item 850035.

NOD Mice Are Defective in Proteasome Production and Activation of NF-κB

Takuma Hayashi, Denise Faustman

Mol Cell Biol. 1999 Dec; 19(12): 8646–8659. doi: 10.1128/mcb.19.12.8646

PMCID:: PMC85003

Abstract Article PDF–2.2M

Select item 461596.

Molecular basis of genetic polymorphism in major histocompatibility complex-linked proteasome gene (Lmp-2).

P Zhou, H Cao, M Smart, C David

Proc Natl Acad Sci U S A. 1993 Apr 1; 90(7): 2681–2684. doi: 10.1073/pnas.90.7.2681

PMCID:: PMC46159

Summary Page Browse PDF–925K

Select item 86132907.

Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency

Nobuo Kanazawa, Hiroaki Hemmi, Noriko Kinjo, Hidenori Ohnishi, Jun Hamazaki, Hiroyuki Mishima, Akira Kinoshita, Tsunehiro Mizushima, Satoru Hamada, Kazuya Hamada, Norio Kawamoto, Saori Kadowaki, Yoshitaka Honda, Kazushi Izawa, Ryuta Nishikomori, Miyuki Tsumura, Yusuke Yamashita, Shinobu Tamura, Takashi Orimo, Toshiya Ozasa, Takashi Kato, Izumi Sasaki, Yuri Fukuda-Ohta, Naoko Wakaki-Nishiyama, Yutaka Inaba, Kayo Kunimoto, Satoshi Okada, Takeshi Taketani, Koichi Nakanishi, Shigeo Murata, Koh-ichiro Yoshiura, Tsuneyasu Kaisho

Nat Commun. 2021; 12: 6819. Published online 2021 Nov 24. doi: 10.1038/s41467-021-27085-y

PMCID:: PMC8613290

Abstract Article PDF–2.7M

Select item 37629758.

Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8⁺ T Cell Responses

Damien Zanker, Jason Waithman, Jonathan W. Yewdell, Weisan Chen

J Immunol. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: J Immunol. 2013 Jul 1; 191(1): 52–59. Published online 2013 May 24. doi: 10.4049/jimmunol.1300802

PMCID:: PMC3762975

Abstract Article PDF–2.1M

Select item 32409659.

Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy

Takuma Hayashi, Akiko Horiuchi, Kenji Sano, Nobuyoshi Hiraoka, Mari Kasai, Tomoyuki Ichimura, Tamotsu Sudo, Yoh-ichi Tagawa, Ryuichiro Nishimura, Osamu Ishiko, Yae Kanai, Nobuo Yaegashi, Hiroyuki Aburatani, Tanri Shiozawa, Ikuo Konishi

Sci Rep. 2011; 1: 180. Published online 2011 Dec 5. doi: 10.1038/srep00180

PMCID:: PMC3240965

Abstract Article PDF–2.6M

Select item 288368510.

Evidence for a Role of Immunoproteasomes in Regulating Cardiac Muscle Mass in Diabetic Mice

Lingyun Zu, Djahida Bedja, Karen Fox-Talbot, Kathleen L. Gabrielson, Luc Van Kaer, Lewis C. Becker, Zheqing P. Cai

J Mol Cell Cardiol. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: J Mol Cell Cardiol. 2010 Jul; 49(1): 5–15. Published online 2010 Feb 12. doi: 10.1016/j.yjmcc.2010.02.007

PMCID:: PMC2883685

Abstract Article PDF–2.2M

Select item 179744511.

Role of Immunoproteasome Catalytic Subunits in the Immune Response to Hepatitis B Virus

Michael D. Robek, Mayra L. Garcia, Bryan S. Boyd, Francis V. Chisari

J Virol. 2007 Jan; 81(2): 483–491. Published online 2006 Nov 1. doi: 10.1128/JVI.01779-06

PMCID:: PMC1797445

Abstract Article PDF–443K

Select item 809915012.

The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis

Timothy French, Nicole Israel, Henning Peter Düsedau, Anne Tersteegen, Johannes Steffen, Clemens Cammann, Eylin Topfstedt, Daniela Dieterich, Thomas Schüler, Ulrike Seifert, Ildiko Rita Dunay

Front Immunol. 2021; 12: 619465. Published online 2021 Apr 21. doi: 10.3389/fimmu.2021.619465

PMCID:: PMC8099150

Abstract Article PDF–3.6M

Select item 316106013.

Immunoproteasome-Deficiency Has No Effects on NK Cell Education, but Confers Lymphocytes into Targets for NK Cells in Infected Wild-Type Mice

Mary J. G. van Helden, Natascha de Graaf, Cornelis P. J. Bekker, Claire J. P. Boog, Dietmar M. W. Zaiss, Alice J. A. M. Sijts

PLoS One. 2011; 6(8): e23769. Published online 2011 Aug 24. doi: 10.1371/journal.pone.0023769

PMCID:: PMC3161060

Abstract Article PDF–912K

Select item 294109414.

Unexpected Role for the Immunoproteasome Subunit LMP2 in Antiviral Humoral and Innate Immune Responses

Scott E. Hensley, Damien Zanker, Brian P. Dolan, Alexandre David, Heather D. Hickman, Alan C. Embry, Cara N. Skon, Kristie M. Grebe, Thomas A. Griffin, Weisan Chen, Jack R. Bennink, Jonathan W. Yewdell

J Immunol. Author manuscript; available in PMC 2011 Apr 15.

Published in final edited form as: J Immunol. 2010 Apr 15; 184(8): 4115–4122. Published online 2010 Mar 12. doi: 10.4049/jimmunol.0903003

PMCID:: PMC2941094

Abstract Article PDF–1.7M

Select item 628079615.

Co‐inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity

Michael Basler, Michelle M Lindstrom, Jacob J LaStant, J Michael Bradshaw, Timothy D Owens, Christian Schmidt, Elmer Maurits, Christopher Tsu, Herman S Overkleeft, Christopher J Kirk, Claire L Langrish, Marcus Groettrup

EMBO Rep. 2018 Dec; 19(12): e46512. Published online 2018 Oct 2. doi: 10.15252/embr.201846512

PMCID:: PMC6280796

Abstract Article PDF–1.2M

Select item 443322216.

Immunoproteasome Deficiency Protects in the Retina after Optic Nerve Crush

Nathan J. Schuld, Stacy A. Hussong, Rebecca J. Kapphahn, Ute Lehmann, Heidi Roehrich, Abrar A. Rageh, Neal D. Heuss, Wendy Bratten, Dale S. Gregerson, Deborah A. Ferrington

PLoS One. 2015; 10(5): e0126768. Published online 2015 May 15. doi: 10.1371/journal.pone.0126768

PMCID:: PMC4433222

Abstract Article PDF–3.3M

Select item 400209017.

IFN-γ Directly Controls IL-33 Protein Level through a STAT1- and LMP2-dependent Mechanism

Pavel Kopach, Virginia Lockatell, Edward M. Pickering, Ronald E. Haskell, Richard D. Anderson, Jeffrey D. Hasday, Nevins W. Todd, Irina G. Luzina, Sergei P. Atamas

J Biol Chem. 2014 Apr 25; 289(17): 11829–11843. Published online 2014 Mar 11. doi: 10.1074/jbc.M113.534396

PMCID:: PMC4002090

Abstract Article PDF–1.5M

Select item 391128018.

Identification of the Immunoproteasome as a Novel Regulator of Skeletal Muscle Differentiation

Ziyou Cui, Soyun Michelle Hwang, Aldrin V. Gomes

Mol Cell Biol. 2014 Jan; 34(1): 96–109. doi: 10.1128/MCB.00622-13

PMCID:: PMC3911280

Abstract Article PDF–3.8M

Select item 326288819.

Mice completely lacking immunoproteasomes display major alterations in antigen presentation

Eleanor Z Kincaid, Jenny W Che, Ian York, Hernando Escobar, Eduardo Reyes-Vargas, Julio C. Delgado, Raymond M Welsh, Margaret L. Karow, Andrew J. Murphy, David M. Valenzuela, George D. Yancopoulos, Kenneth L Rock

Nat Immunol. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Nat Immunol. 2012 Feb; 13(2): 129–135. Published online 2011 Dec 25. doi: 10.1038/ni.2203

PMCID:: PMC3262888

Abstract Article PDF–1.0M

Select item 277341820.

Immunoproteasome Overexpression Underlies the Pathogenesis of Thyroid Oncocytes and Primary Hypothyroidism: Studies in Humans and Mice

Hiroaki J. Kimura, Cindy Y. Chen, Shey-Cherng Tzou, Roberto Rocchi, Melissa A. Landek-Salgado, Koichi Suzuki, Miho Kimura, Noel R. Rose, Patrizio Caturegli

PLoS One. 2009; 4(11): e7857. Published online 2009 Nov 17. doi: 10.1371/journal.pone.0007857

PMCID:: PMC2773418

Abstract Article PDF–536K

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