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Select item 99451791.

GPR30-mediated non-classic estrogen pathway in mast cells participates in endometriosis pain via the production of FGF2

Xinxin Xu, Jianzhang Wang, Xinyue Guo, Yichen Chen, Shaojie Ding, Gen Zou, Libo Zhu, Tiantian Li, Xinmei Zhang

Front Immunol. 2023; 14: 1106771. Published online 2023 Feb 8. doi: 10.3389/fimmu.2023.1106771

PMCID:: PMC9945179

Abstract Article PDF–7.7M

Select item 92150542.

Positive interaction between GPER and β-alanine in the dorsal root ganglion uncovers potential mechanisms: mediating continuous neuronal sensitization and neuroinflammation responses in neuropathic pain

Zhenzhen Xu, Wanli Xie, Yiqi Feng, Yanting Wang, Xia Li, Jie Liu, Yue Xiong, Yuyao He, Lu Chen, Guoyang Liu, Qingping Wu

J Neuroinflammation. 2022; 19: 164. Published online 2022 Jun 21. doi: 10.1186/s12974-022-02524-9

PMCID:: PMC9215054

Abstract Article PDF–16M

Select item 76044963.

Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway

Abdulhafiz Imam Aliagan, Ngonidzashe B. Madungwe, Nathalie Tombo, Yansheng Feng, Jean C. Bopassa

Front Endocrinol (Lausanne) 2020; 11: 579161. Published online 2020 Oct 19. doi: 10.3389/fendo.2020.579161

PMCID:: PMC7604496

Abstract Article PDF–3.0M

Select item 71755614.

GPR30 receptor promotes preoperative anxiety-induced postoperative hyperalgesia by up-regulating GABA_A-α4β1δ subunits in periaqueductal gray in female rats

Ming Jiang, Yu’e Sun, Yishan Lei, Fan Hu, Zhengrong Xia, Yue Liu, Zhengliang Ma, Xiaoping Gu

BMC Anesthesiol. 2020; 20: 93. Published online 2020 Apr 22. doi: 10.1186/s12871-020-01017-7

PMCID:: PMC7175561

Abstract Article PDF–4.2M

Select item 66609115.

Expression of G protein-coupled receptor 30 in the spinal somatosensory system

Keiko Takanami, Hirotaka Sakamoto, Ken-Ichi Matsuda, Koji Hosokawa, Mayumi Nishi, Eric R. Prossnitz, Mitsuhiro Kawata

Brain Res. Author manuscript; available in PMC 2019 Jul 27.

Published in final edited form as: Brain Res. 2010 Jan 15; 1310: 17–28. Published online 2009 Nov 11. doi: 10.1016/j.brainres.2009.11.004

PMCID:: PMC6660911

Abstract Article PDF–1.4M

Select item 66266236.

GPR30 Expression Is Required for the Mineralocorticoid Receptor-Independent Rapid Vascular Effects of Aldosterone

Robert Gros, Qingming Ding, Larry A. Sklar, Eric E. Prossnitz, Jeffrey B. Arterburn, Jozef Chorazyczewski, Ross D. Feldman

Hypertension. Author manuscript; available in PMC 2019 Jul 14.

Published in final edited form as: Hypertension. 2011 Mar; 57(3): 442–451. Published online 2011 Jan 17. doi: 10.1161/HYPERTENSIONAHA.110.161653

PMCID:: PMC6626623

Abstract Article PDF–958K

Select item 62081547.

ATTENUATION OF MICROBIOTAL DYSBIOSIS AND HYPERTENSION IN A CRISPR/CAS9 GENE ABLATION RAT MODEL OF GPER1

Harshal Waghulde, Xi Cheng, Sarah Galla, Blair Mell, Jingwei Cai, Shondra M. Pruett-Miller, Guillermo Vazquez, Andrew Patterson, Matam Vijay-kumar, Bina Joe

Hypertension. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Hypertension. 2018 Nov; 72(5): 1125–1132. doi: 10.1161/HYPERTENSIONAHA.118.11175

PMCID:: PMC6208154

Abstract Article PDF–1.3M

Select item 53419918.

GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain

Jie Luo, Xiaoxia Huang, Yali Li, Yang Li, Xueqin Xu, Yan Gao, Ruoshi Shi, Wanjun Yao, Juying Liu, Changbin Ke

Oncotarget. 2016 Nov 8; 7(45): 73462–73472. Published online 2016 Sep 6. doi: 10.18632/oncotarget.11867

PMCID:: PMC5341991

Abstract Article PDF–19M

Select item 48845429.

Activation of GPR30 improves exercise capacity and skeletal muscle strength in senescent female Fischer344×Brown Norway rats

Hao Wang, Allan Alencar, Marina Lin, Xuming Sun, Roberto T. Sudo, Gisele Zapata-Sudo, Dawn A. Lowe, Leanne Groban

Biochem Biophys Res Commun. Author manuscript; available in PMC 2017 Jun 17.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Jun 17; 475(1): 81–86. Published online 2016 May 10. doi: 10.1016/j.bbrc.2016.05.040

PMCID:: PMC4884542

Abstract Article PDF–721K

Select item 461368810.

Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic rats

Wen-Bo Kang, Yu Cong, Jiang-Ying Ru, Si-Qi Ying, Ting Zhu, Dong-Sheng Wang, Xiao-Wei Liu, Gang Liu, Jian-Ning Zhao

Biosci Rep. 2015 Aug; 35(4): e00239. Prepublished online 2015 Jul 3. Published online 2015 Aug 18. doi: 10.1042/BSR20150146

PMCID:: PMC4613688

Abstract Article PDF–1.5M

Select item 446436111.

Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection

WAN-LI LI, WEI XIANG, YE PING

Mol Med Rep. 2015 Aug; 12(2): 2425–2430. Published online 2015 Apr 24. doi: 10.3892/mmr.2015.3674

PMCID:: PMC4464361

Abstract Article PDF–885K

Select item 444933312.

Activation of GPR30 inhibits cardiac fibroblast proliferation

Hao Wang, Zhuo Zhao, Marina Lin, Leanne Groban

Mol Cell Biochem. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Mol Cell Biochem. 2015 Jul; 405(0): 135–148. Published online 2015 Apr 17. doi: 10.1007/s11010-015-2405-3

PMCID:: PMC4449333

Abstract Article PDF–2.1M

Select item 436316013.

GPR30 Decreases Cardiac Chymase/Angiotensin II by Inhibiting Local Mast Cell Number

Zhuo Zhao, Hao Wang, Marina Lin, Leanne Groban

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Mar 27.

Published in final edited form as: Biochem Biophys Res Commun. 2015 Mar 27; 459(1): 131–136. Published online 2015 Feb 21. doi: 10.1016/j.bbrc.2015.02.082