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Select item 59219671.

Conservation of the separase regulatory domain

Michael Melesse, Joshua N. Bembenek, Igor B. Zhulin

Biol Direct. 2018; 13: 7. Published online 2018 Apr 27. doi: 10.1186/s13062-018-0210-0

PMCID:: PMC5921967

Abstract Article PDF–843K

Select item 41715202.

Protease-Dead Separase Is Dominant Negative in the C. elegans Embryo

Diana M. Mitchell, Lindsey R. Uehlein-Klebanow, Joshua N. Bembenek

PLoS One. 2014; 9(9): e108188. Published online 2014 Sep 22. doi: 10.1371/journal.pone.0108188

PMCID:: PMC4171520

Abstract Article PDF–1.8M

Select item 56383623.

Protease dead separase inhibits chromosome segregation and RAB-11 vesicle trafficking

Xiaofei Bai, Joshua N. Bembenek

Cell Cycle. 2017; 16(20): 1902–1917. Published online 2017 Aug 18. doi: 10.1080/15384101.2017.1363936

Correction in:: Cell Cycle. 2018; 17(12): 1524.

PMCID:: PMC5638362

Abstract Article PDF–2.1M

Select item 53851334.

Cryo-EM structure of a separase-securin complex at near-atomic resolution

Andreas Boland, Thomas G. Martin, Ziguo Zhang, Jing Yang, Xiao-chen Bai, Leifu Chang, Sjors H.W. Scheres, David Barford

Nat Struct Mol Biol. Author manuscript; available in PMC 2017 Sep 6.

Published in final edited form as: Nat Struct Mol Biol. 2017 Apr; 24(4): 414–418. Published online 2017 Mar 6. doi: 10.1038/nsmb.3386

PMCID:: PMC5385133

Abstract Article PDF–2.3M

Select item 48524615.

A closed conformation of the Caenorhabditis elegans separase–securin complex

Gudrun Bachmann, Mark W. Richards, Anja Winter, Fabienne Beuron, Edward Morris, Richard Bayliss

Open Biol. 2016 Apr; 6(4): 160032. Published online 2016 Apr 13. doi: 10.1098/rsob.160032

PMCID:: PMC4852461

Abstract Article PDF–1.0M

Select item 31660366.

Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans

Christopher T. Richie, Joshua N. Bembenek, Barry Chestnut, Tokiko Furuta, Jill M. Schumacher, Matthew Wallenfang, Andy Golden

J Cell Sci. 2011 Sep 1; 124(17): 2903–2913. doi: 10.1242/jcs.073379

PMCID:: PMC3166036

Abstract Article

Select item 102002807.

Functional analysis of a novel de novo variant in PPP5C associated with microcephaly, seizures, and developmental delay

Sara M. Fielder, Jill A. Rosenfeld, Lindsay C. Burrage, Lisa Emrick, Seema Lalani, Ruben Attali, Joshua N. Bembenek, Hieu Hoang, Dustin Baldridge, Gary A. Silverman, Undiagnosed Diseases Network, Tim Schedl, Stephen C. Pak

Mol Genet Metab. Author manuscript; available in PMC 2023 May 21.

Published in final edited form as: Mol Genet Metab. 2022 May; 136(1): 65–73. Published online 2022 Mar 22. doi: 10.1016/j.ymgme.2022.03.007

PMCID:: PMC10200280

Abstract Article PDF–1.1M

Select item 59197288.

Genetic Identification of Separase Regulators in Caenorhabditis elegans

Michael Melesse, Dillon E. Sloan, Joseph T. Benthal, Quincey Caylor, Krishen Gosine, Xiaofei Bai, Joshua N. Bembenek

G3 (Bethesda) 2018 Feb; 8(2): 695–705. Published online 2017 Dec 14. doi: 10.1534/g3.117.300298

PMCID:: PMC5919728

Abstract Article PDF–2.0M

Select item 44124059.

Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans

Joost Monen, Neil Hattersley, Andrew Muroyama, Deanna Stevens, Karen Oegema, Arshad Desai

PLoS One. 2015; 10(4): e0125382. Published online 2015 Apr 28. doi: 10.1371/journal.pone.0125382

PMCID:: PMC4412405

Abstract Article PDF–1.0M

Select item 283301610.

A Role for Separase in the Regulation of RAB-11-positive Vesicles at the Cleavage Furrow and Midbody

Joshua N. Bembenek, John G. White, Yixian Zheng

Curr Biol. Author manuscript; available in PMC 2010 Aug 9.

Published in final edited form as: Curr Biol. 2010 Feb 9; 20(3): 259–264. Published online 2010 Jan 28. doi: 10.1016/j.cub.2009.12.045

PMCID:: PMC2833016

Abstract Article PDF–3.0M

Select item 714583011.

Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death

Pan Young Jeong, Ashish Kumar, Pradeep M. Joshi, Joel H. Rothman

Sci Rep. 2020; 10: 6159. Published online 2020 Apr 9. doi: 10.1038/s41598-020-63081-w

PMCID:: PMC7145830

Abstract Article PDF–1.6M

Select item 359387212.

Meiotic HORMA domain proteins prevent untimely centriole disengagement during Caenorhabditis elegans spermatocyte meiosis

Mara Schvarzstein, Divya Pattabiraman, Joshua N. Bembenek, Anne M. Villeneuve

Proc Natl Acad Sci U S A. 2013 Mar 5; 110(10): E898–E907. Published online 2013 Feb 11. doi: 10.1073/pnas.1213888110

PMCID:: PMC3593872

Abstract Article PDF–2.3M

Select item 320180213.

Initial diameter of the polar body contractile ring is minimized by the centralspindlin complex

Amy S. Fabritius, Jonathan R. Flynn, Francis J. McNally

Dev Biol. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Dev Biol. 2011 Nov 1; 359(1): 137–148. Published online 2011 Aug 25. doi: 10.1016/j.ydbio.2011.08.013

PMCID:: PMC3201802

Abstract Article PDF–3.2M

Select item 750837414.

Excess crossovers impede faithful meiotic chromosome segregation in C. elegans

Jeremy A. Hollis, Marissa L. Glover, Aleesa J. Schlientz, Cori K. Cahoon, Bruce Bowerman, Sarah M. Wignall, Diana E. Libuda

PLoS Genet. 2020 Sep; 16(9): e1009001. Published online 2020 Sep 4. doi: 10.1371/journal.pgen.1009001

PMCID:: PMC7508374

Abstract Article PDF–5.0M

Select item 550757915.

Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase

Joshua N. Bembenek, Christopher T. Richie, Jayne M. Squirrell, Jay M. Campbell, Kevin W. Eliceiri, Dmitry Poteryaev, Anne Spang, Andy Golden, John G. White

Development. Author manuscript; available in PMC 2017 Jul 12.

Published in final edited form as: Development. 2007 Nov; 134(21): 3837–3848. Published online 2007 Oct 3. doi: 10.1242/dev.011361