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Select item 113014231.

ATP-binding cassette family C member 1 constrains metabolic responses to high-fat diet in male mice

Elisa Villalobos, Allende Miguelez-Crespo, Ruth A Morgan, Lisa Ivatt, Mhairi Paul, Joanna P Simpson, Natalie Z M Homer, Dominic Kurian, Judit Aguilar, Rachel A Kline, Thomas M Wishart, Nicholas M Morton, Roland H Stimson, Ruth Andrew, Brian R Walker, Mark Nixon

J Endocrinol. 2024 Aug 1; 262(2): e240024. Prepublished online 2024 Jun 3. Published online 2024 Jul 3. doi: 10.1530/JOE-24-0024

PMCID:: PMC11301423

Abstract Article PDF–3.7M

Select item 112258912.

ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity

Jing Liu, Yijiang Bai, Yong Feng, Xianlin Liu, Bo Pang, Shuai Zhang, Mengzhu Jiang, Anhai Chen, Huping Huang, Yongjia Chen, Jie Ling, Lingyun Mei

Redox Biol. 2024 Aug; 74: 103218. Published online 2024 Jun 1. doi: 10.1016/j.redox.2024.103218

PMCID:: PMC11225891

Abstract Article PDF–12M

Select item 61890463.

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae

Shilpi Chandra, James Gray, William B. Kiosses, Archana Khurana, Kaori Hitomi, Catherine M. Crosby, Ashu Chawla, Zheng Fu, Meng Zhao, Natacha Veerapen, Stewart K. Richardson, Steven A. Porcelli, Gurdyal Besra, Amy R. Howell, Sonia Sharma, Bjoern Peters, Mitchell Kronenberg

Nat Commun. 2018; 9: 4279. Published online 2018 Oct 15. doi: 10.1038/s41467-018-06646-8

PMCID:: PMC6189046

Abstract Article PDF–7.3M

Select item 49147934.

Loss of Mrp1 Potentiates Doxorubicin-Induced Cytotoxicity in Neonatal Mouse Cardiomyocytes and Cardiac Fibroblasts

Wei Zhang, Daret St Clair, Allan Butterfield, Mary Vore

Toxicol Sci. 2016 May; 151(1): 44–56. Published online 2016 Jan 27. doi: 10.1093/toxsci/kfw021

PMCID:: PMC4914793

Abstract Article PDF–762K

Select item 48589625.

Multidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial Cells

Gayle M. Gordillo, Ayan Biswas, Savita Khanna, James M. Spieldenner, Xueliang Pan, Chandan K. Sen

J Biol Chem. 2016 May 6; 291(19): 10089–10103. Published online 2016 Mar 9. doi: 10.1074/jbc.M115.688879

Correction in:: J Biol Chem. 2016 Jul 1; 291(27): 14394.

PMCID:: PMC4858962

Abstract Article PDF–3.4M

Select item 40511556.

Lipopolysaccharide Increases the Expression of Multidrug Resistance-Associated Protein 1 (ABCC1) in Macrophages

Peter S. Silverstein, Kenneth L. Audus, Nilofer Qureshi, Anil Kumar

J Neuroimmune Pharmacol. Author manuscript; available in PMC 2014 Jun 10.

Published in final edited form as: J Neuroimmune Pharmacol. 2010 Dec; 5(4): 516–520. Published online 2009 Nov 6. doi: 10.1007/s11481-009-9180-4

PMCID:: PMC4051155

Abstract Article PDF–652K

Select item 28628347.

Mice lacking Mrp1 have reduced testicular steroid hormone levels and alterations in steroid biosynthetic enzymes

JEFFREY C. SIVILS, IVEN GONZALEZ, LISA J. BAIN

Gen Comp Endocrinol. Author manuscript; available in PMC 2011 May 15.

Published in final edited form as: Gen Comp Endocrinol. 2010 May 15; 167(1): 51–59. Published online 2010 Feb 21. doi: 10.1016/j.ygcen.2010.02.019

PMCID:: PMC2862834

Abstract Article PDF–990K

Select item 22133898.

Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage

Jan Wijnholds, George L. Scheffer, Martin van der Valk, Paul van der Valk, Jos H. Beijnen, Rik J. Scheper, Piet Borst

J Exp Med. 1998 Sep 7; 188(5): 797–808. doi: 10.1084/jem.188.5.797

PMCID:: PMC2213389

Abstract Article PDF–716K

Select item 60340769.

Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection

Andrew Zukauskas, Randall J. Mrsny, Paula Cortés Barrantes, Jerrold R. Turner, John M. Leong, Beth A. McCormick

mSphere. 2018 Jul-Aug; 3(4): e00303-18. Published online 2018 Jul 5. doi: 10.1128/mSphere.00303-18

PMCID:: PMC6034076

Abstract Article PDF–1.0M

Select item 471525910.

Nrf2 Regulates the Sensitivity of Mouse Keratinocytes to Nitrogen Mustard via Multidrug Resistance-Associated Protein 1 (Mrp1)

Ronald G. Udasin, Xia Wen, Kristin M. Bircsak, Lauren M. Aleksunes, Michael P. Shakarjian, Ah-Ng Tony Kong, Diane E. Heck, Debra L. Laskin, Jeffrey D. Laskin

Toxicol Sci. 2016 Jan; 149(1): 202–212. Published online 2015 Oct 9. doi: 10.1093/toxsci/kfv226

PMCID:: PMC4715259

Abstract Article PDF–571K

Select item 372904411.

Loss of Mrp1 alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner

Jeffrey C. Sivils, Tiffany M. Ancrum, Lisa J. Bain

J Appl Toxicol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: J Appl Toxicol. 2013 Aug; 33(8): 766–773. Published online 2012 Apr 23. doi: 10.1002/jat.2727

PMCID:: PMC3729044

Abstract Article PDF–1.4M

Select item 358780812.

Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood–brain and blood–spinal cord barriers

Tara A Cartwright, Christopher R Campos, Ronald E Cannon, David S Miller

J Cereb Blood Flow Metab. 2013 Mar; 33(3): 381–388. Published online 2012 Nov 21. doi: 10.1038/jcbfm.2012.174

PMCID:: PMC3587808

Abstract Article PDF–561K

Select item 355484113.

Metallothionein blocks oxidative DNA damage in vitro

Wei Qu, Jingbo Pi, Michael P. Waalkes

Arch Toxicol. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Arch Toxicol. 2013 Feb; 87(2): 311–321. Published online 2012 Aug 23. doi: 10.1007/s00204-012-0927-y

PMCID:: PMC3554841

Abstract Article PDF–1.9M

Select item 190648414.

Mice lacking the multidrug resistance protein 1 have a transiently impaired immune response during tuberculosis

A VERBON, J C LEEMANS, S WEIJER, S FLORQUIN, T VAN DER POLL

Clin Exp Immunol. 2002 Oct; 130(1): 32–36. doi: 10.1046/j.1365-2249.2002.01952.x

PMCID:: PMC1906484

Abstract Article PDF–511K

Select item 178017915.

Interferon-γ Plays Protective Roles in Sodium Arsenite-Induced Renal Injury by Up-Regulating Intrarenal Multidrug Resistance-Associated Protein 1 Expression

Akihiko Kimura, Yuko Ishida, Takahito Hayashi, Takashi Wada, Hitoshi Yokoyama, Takeshi Sugaya, Naofumi Mukaida, Toshikazu Kondo

Am J Pathol. 2006 Oct; 169(4): 1118–1128. doi: 10.2353/ajpath.2006.060024

PMCID:: PMC1780179

Abstract Article PDF–3.2M

Select item 412566516.

Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice

Bao-Jin Zhai, Ze-Yong Shao, Chun-Liang Zhao, Kai Hu, Feng Wu

World J Gastroenterol. 2006 Nov 7; 12(41): 6614–6619. Published online 2006 Nov 7. doi: 10.3748/wjg.v12.i41.6614

PMCID:: PMC4125665

Abstract Article PDF–881K

Select item 330773417.

Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux

Parameswaran G. Sreekumar, Christine Spee, Stephen J. Ryan, Susan P. C. Cole, Ram Kannan, David R. Hinton

PLoS One. 2012; 7(3): e33420. Published online 2012 Mar 19. doi: 10.1371/journal.pone.0033420

PMCID:: PMC3307734

Abstract Article PDF–1013K

Select item 324911518.

Nitric Oxide Storage and Transport in Cells Are Mediated by Glutathione S-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes

Hiu Chuen Lok, Yohan Suryo Rahmanto, Clare L. Hawkins, Danuta S. Kalinowski, Charles S. Morrow, Alan J. Townsend, Prem Ponka, Des R. Richardson

J Biol Chem. 2012 Jan 2; 287(1): 607–618. Published online 2011 Nov 14. doi: 10.1074/jbc.M111.310987

PMCID:: PMC3249115

Abstract Article PDF–4.7M

Select item 195050519.

Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice

Margaretha van der Deen, Wim Timens, Hetty Timmer-Bosscha, Barry W van der Strate, Rik J Scheper, Dirkje S Postma, Elisabeth G de Vries, Huib A Kerstjens

Respir Res. 2007; 8(1): 49. Published online 2007 Jul 7. doi: 10.1186/1465-9921-8-49

PMCID:: PMC1950505

Abstract Article PDF–759K

Select item 109178020.

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception

Noam Zelcer, Koen van de Wetering, Michel Hillebrand, Elise Sarton, Annemieke Kuil, Peter R. Wielinga, Thomas Tephly, Albert Dahan, Jos H. Beijnen, Piet Borst

Proc Natl Acad Sci U S A. 2005 May 17; 102(20): 7274–7279. Published online 2005 May 10. doi: 10.1073/pnas.0502530102