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Select item 100956021.

Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice

Frank A. Simmen, John Mark P. Pabona, Ahmed Al-Dwairi, Iad Alhallak, Maria Theresa E. Montales, Rosalia C. M. Simmen

Int J Mol Sci. 2023 Apr; 24(7): 6613. Published online 2023 Apr 1. doi: 10.3390/ijms24076613

PMCID:: PMC10095602

Abstract Article PDF–3.6M

Select item 48919822.

Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage

Ling Liu, Supriya Shah, Jing Fan, Junyoung O Park, Kathryn E Wellen, Joshua D Rabinowitz

Nat Chem Biol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Nat Chem Biol. 2016 May; 12(5): 345–352. Published online 2016 Mar 21. doi: 10.1038/nchembio.2047

PMCID:: PMC4891982

Abstract Article PDF–1.0M

Select item 42346503.

Enhanced Gastrointestinal Expression of Cytosolic Malic Enzyme (ME1) Induces Intestinal and Liver Lipogenic Gene Expression and Intestinal Cell Proliferation in Mice

Ahmed Al-Dwairi, Adam R. Brown, John Mark P. Pabona, Trang H. Van, Hamdan Hamdan, Charles P. Mercado, Charles M. Quick, Patricia A. Wight, Rosalia C. M. Simmen, Frank A. Simmen

PLoS One. 2014; 9(11): e113058. Published online 2014 Nov 17. doi: 10.1371/journal.pone.0113058

PMCID:: PMC4234650

Abstract Article PDF–1.9M

Select item 34642854.

Cytosolic Malic Enzyme 1 (ME1) Mediates High Fat Diet-Induced Adiposity, Endocrine Profile, and Gastrointestinal Tract Proliferation-Associated Biomarkers in Male Mice

Ahmed Al-Dwairi, John Mark P. Pabona, Rosalia C. M. Simmen, Frank A. Simmen

PLoS One. 2012; 7(10): e46716. Published online 2012 Oct 4. doi: 10.1371/journal.pone.0046716

PMCID:: PMC3464285

Abstract Article PDF–1.8M

Select item 111564125.

Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions

Jonathan M. Alektiar, Mengrou Shan, Megan D. Radyk, Li Zhang, Christopher J. Halbrook, Lin Lin, Carlos Espinoza, Ivan F. Mier, Brooke L. Lavoie, Lucie Salvatore, Marina Pasca di Magliano, Lewis C. Cantley, Jacob L. Mueller, Costas A. Lyssiotis

PLoS One. 2024; 19(6): e0303577. Published online 2024 Jun 6. doi: 10.1371/journal.pone.0303577

PMCID:: PMC11156412

Abstract Article PDF–2.1M

Select item 45026406.

Mutant KRAS associated malic enzyme 1 expression is a predictive marker for radiation therapy response in non-small cell lung cancer

Gaurab Chakrabarti

Radiat Oncol. 2015; 10: 145. Published online 2015 Jul 16. doi: 10.1186/s13014-015-0457-x

PMCID:: PMC4502640

Abstract Article PDF–813K

Select item 27776327.

Malic enzyme is present in mouse islets and modulates insulin secretion

Jianxiang Xu, Junying Han, Yun Shi Long, Jennifer Lock, Gordon C. Weir, Paul N. Epstein, Ye Qi Liu

Diabetologia. Author manuscript; available in PMC 2009 Nov 16.

Published in final edited form as: Diabetologia. 2008 Dec; 51(12): 2281–2289. Published online 2008 Sep 19. doi: 10.1007/s00125-008-1155-0

PMCID:: PMC2777632

Abstract Article PDF–602K

Select item 25708848.

Silencing of Cytosolic or Mitochondrial Isoforms of Malic Enzyme Has No Effect on Glucose-stimulated Insulin Secretion from Rodent Islets

Sarah M. Ronnebaum, Mette V. Jensen, Hans E. Hohmeier, Shawn C. Burgess, Yun-Ping Zhou, Su Qian, Douglas MacNeil, Andrew Howard, Nancy Thornberry, Olga Ilkayeva, Danhong Lu, A. Dean Sherry, Christopher B. Newgard

J Biol Chem. 2008 Oct 24; 283(43): 28909–28917. doi: 10.1074/jbc.M804665200

PMCID:: PMC2570884

Abstract Article PDF–598K

Select item 26923979.

Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion

Emma Heart, Gary W. Cline, Leon P. Collis, Rebecca L. Pongratz, Joshua P. Gray, Peter J. S. Smith

Am J Physiol Endocrinol Metab. 2009 Jun; 296(6): E1354–E1362. Published online 2009 Mar 17. doi: 10.1152/ajpendo.90836.2008

PMCID:: PMC2692397

Abstract Article

Select item 120205510.

Application of the Ovarian Teratoma Mapping Method in the Mouse

Janan T. Eppig, Eva M. Eicher

Genetics. 1983 Apr; 103(4): 797–812. doi: 10.1093/genetics/103.4.797

PMCID:: PMC1202055

Summary PDF–864K

Select item 218592911.

An autosomal dominant gene regulates the extent of 9-O-acetylation of murine erythrocyte sialic acids. A probable explanation for the variation in capacity to activate the human alternate complement pathway

J Exp Med. 1980 Sep 1; 152(3): 532–544. doi: 10.1084/jem.152.3.532

PMCID:: PMC2185929

Summary PDF–707K

Select item 34524112.

Localization of cytochrome P1-450 and P3-450 genes to mouse chromosome 9.

R H Tukey, P A Lalley, D W Nebert

Proc Natl Acad Sci U S A. 1984 May; 81(10): 3163–3166. doi: 10.1073/pnas.81.10.3163

PMCID:: PMC345241

Summary Page Browse PDF–1.0M

Select item 283794713.

Validation of Candidate Causal Genes for Abdominal Obesity Which Affect Shared Metabolic Pathways and Networks

Xia Yang, Joshua L. Deignan, Hongxiu Qi, Jun Zhu, Su Qian, Judy Zhong, Gevork Torosyan, Sana Majid, Brie Falkard, Robert R. Kleinhanz, Jenny Karlsson, Lawrence W. Castellani, Sheena Mumick, Kai Wang, Tao Xie, Michael Coon, Chunsheng Zhang, Daria Estrada-Smith, Charles R. Farber, Susanna S. Wang, Atila Van Nas, Anatole Ghazalpour, Bin Zhang, Douglas J. MacNeil, John R. Lamb, Katrina M. Dipple, Marc L. Reitman, Margarete Mehrabian, Pek Y. Lum, Eric E. Schadt, Aldons J. Lusis, Thomas A. Drake

Nat Genet. Author manuscript; available in PMC 2010 Mar 15.

Published in final edited form as: Nat Genet. 2009 Apr; 41(4): 415–423. Published online 2009 Mar 8. doi: 10.1038/ng.325

PMCID:: PMC2837947

Abstract Article PDF–580K

Select item 5529914.

Activation of erythropoietin receptors by Friend viral gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene.

M E Hoatlin, S L Kozak, F Lilly, A Chakraborti, C A Kozak, D Kabat

Proc Natl Acad Sci U S A. 1990 Dec; 87(24): 9985–9989. doi: 10.1073/pnas.87.24.9985

PMCID:: PMC55299

Summary Page Browse PDF–1.1M

Select item 120233615.

Conserved Linkage within a 4-Cm Region of Mouse Chromosome 9 and Human Chromosome 11

T. K. Antonucci, O. H. Von Deimling, B. B. Rosenblum, L. C. Skow, M. H. Meisler

Genetics. 1984 Jul; 107(3): 463–475. doi: 10.1093/genetics/107.3.463

PMCID:: PMC1202336

Summary PDF–2.7M

Select item 356150016.

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

Peng Jiang, Wenjing Du, Anthony Mancuso, Kathryn E. Wellen, Xiaolu Yang

Nature. Author manuscript; available in PMC 2013 Jul 31.

Published in final edited form as: Nature. 2013 Jan 31; 493(7434): 689–693. Published online 2013 Jan 13. doi: 10.1038/nature11776

PMCID:: PMC3561500

Abstract Article PDF–901K

Select item 168527517.

Mapping of aminoacylase-1 and beta-galactosidase-A to homologous regions of human chromosome 3 and mouse chromosome 9 suggests location of additional genes.

S L Naylor, R W Elliott, J A Brown, T B Shows

Am J Hum Genet. 1982 Mar; 34(2): 235–244.

PMCID:: PMC1685275

Summary Page Browse PDF–1.2M

Select item 121636718.

Use of Two-Dimensional Electrophoresis to Identify and Map New Mouse Genes

Rosemary W. Elliott

Genetics. 1979 Feb; 91(2): 295–308. doi: 10.1093/genetics/91.2.295

PMCID:: PMC1216367

Summary PDF–3.1M

Select item 218658619.

Genetic mapping of ecotropic murine leukemia virus-inducing loci in six inbred strains

J Exp Med. 1982 Feb 1; 155(2): 524–534. doi: 10.1084/jem.155.2.524

PMCID:: PMC2186586

Summary PDF–783K

Select item 209925920.

Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome

Alla A. Bondareva, Mario R. Capecchi, Sonya V. Iverson, Yan Li, Nathan I. Lopez, Olivier Lucas, Gary F. Merrill, Justin R. Prigge, Ashley M. Siders, Maki Wakamiya, Stephanie L. Wallin, Edward E. Schmidt

Free Radic Biol Med. Author manuscript; available in PMC 2007 Nov 29.

Published in final edited form as: Free Radic Biol Med. 2007 Sep 15; 43(6): 911–923. Published online 2007 May 31. doi: 10.1016/j.freeradbiomed.2007.05.026

PMCID:: PMC2099259

Abstract Article PDF–1.0M

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