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Select item 48360301.

Autophagy-mediated longevity is modulated by lipoprotein biogenesis

Nicole E. Seah, C. Daniel de Magalhaes Filho, Anna P. Petrashen, Hope R. Henderson, Jade Laguer, Julissa Gonzalez, Andrew Dillin, Malene Hansen, Louis R. Lapierre

Autophagy. 2016 Feb; 12(2): 261–272. Published online 2015 Dec 15. doi: 10.1080/15548627.2015.1127464

PMCID:: PMC4836030

Abstract Article PDF–1.1M

Select item 66203262.

Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8

Matthew C. Tillman, Manoj Khadka, Jonathon Duffy, Meng C. Wang, Eric A. Ortlund

Sci Rep. 2019; 9: 9966. Published online 2019 Jul 10. doi: 10.1038/s41598-019-46230-8

PMCID:: PMC6620326

Abstract Article PDF–4.6M

Select item 73786113.

Secoisolariciresinol Diglucoside Delays the Progression of Aging-Related Diseases and Extends the Lifespan of Caenorhabditis elegans via DAF-16 and HSF-1

Min Lu, Lin Tan, Xiao-Gang Zhou, Zhong-Lin Yang, Qing Zhu, Jian-Ning Chen, Huai-Rong Luo, Gui-Sheng Wu

Oxid Med Cell Longev. 2020; 2020: 1293935. Published online 2020 Jul 14. doi: 10.1155/2020/1293935

PMCID:: PMC7378611

Abstract Article PDF–1.4M

Select item 39199704.

Loss of NDG-4 extends lifespan and stress resistance in Caenorhabditis elegans

Jeanette Brejning, Steffen Nørgaard, Lone Schøler, Tine H Morthorst, Helle Jakobsen, Gordon J Lithgow, Louise T Jensen, Anders Olsen

Aging Cell. 2014 Feb; 13(1): 156–164. Published online 2013 Nov 28. doi: 10.1111/acel.12165

PMCID:: PMC3919970

Abstract Article PDF–495K

Select item 30579505.

Fatty Acid Desaturation Links Germ Cell Loss to Longevity Through NHR-80/HNF4 in C. elegans

Jérôme Goudeau, Stéphanie Bellemin, Esther Toselli-Mollereau, Mehrnaz Shamalnasab, Yiqun Chen, Hugo Aguilaniu

PLoS Biol. 2011 Mar; 9(3): e1000599. Published online 2011 Mar 15. doi: 10.1371/journal.pbio.1000599

PMCID:: PMC3057950

Abstract Article PDF–825K

Select item 44253536.

Lysosomal Signaling Molecules Regulate Longevity in Caenorhabditis elegans

Andrew Folick, Holly Doebbler Oakley, Yong Yu, Eric H. Armstrong, Manju Kumari, Lucas Sanor, David D. Moore, Eric A. Ortlund, Rudolf Zechner, Meng C. Wang

Science. Author manuscript; available in PMC 2015 May 8.

Published in final edited form as: Science. 2015 Jan 2; 347(6217): 83–86. doi: 10.1126/science.1258857

PMCID:: PMC4425353

Abstract Article PDF–1.5M

Select item 15008107.

Genetic Regulation of Unsaturated Fatty Acid Composition in C. elegans

Trisha J Brock, John Browse, Jennifer L Watts

PLoS Genet. 2006 Jul; 2(7): e108. Prepublished online 2006 Jun 5. Published online 2006 Jul 14. doi: 10.1371/journal.pgen.0020108

PMCID:: PMC1500810

Abstract Article PDF–340K

Select item 88288178.

Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans

Qin-Li Wan, Xiao Meng, Chongyang Wang, Wenyu Dai, Zhenhuan Luo, Zhinan Yin, Zhenyu Ju, Xiaodie Fu, Jing Yang, Qunshan Ye, Zhan-Hui Zhang, Qinghua Zhou

Nat Commun. 2022; 13: 768. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28469-4

PMCID:: PMC8828817

Abstract Article PDF–4.5M

Select item 97778999.

Insight of Silkworm Pupa Oil Regulating Oxidative Stress and Lipid Metabolism in Caenorhabditis elegans

Lina Zhao, Baoxiang Wu, Shuyun Liang, Douyong Min, Hongrui Jiang

Foods. 2022 Dec; 11(24): 4084. Published online 2022 Dec 17. doi: 10.3390/foods11244084

PMCID:: PMC9777899

Abstract Article PDF–2.3M

Select item 419994410.

Mulberry leaf polyphenols delay aging and regulate fat metabolism via the germline signaling pathway in Caenorhabditis elegans

Shanqing Zheng, Sentai Liao, Yuxiao Zou, Zhi Qu, Weizhi Shen, Ying Shi

Age (Dordr) 2014 Dec; 36(6): 9719. Published online 2014 Oct 17. doi: 10.1007/s11357-014-9719-z

PMCID:: PMC4199944

Abstract Article PDF–1.3M

Select item 311970111.

The Adiponectin Receptor Homologs in C. elegans Promote Energy Utilization and Homeostasis

Emma Svensson, Louise Olsen, Catarina Mörck, Christian Brackmann, Annika Enejder, Nils J. Faergeman, Marc Pilon

PLoS One. 2011; 6(6): e21343. Published online 2011 Jun 21. doi: 10.1371/journal.pone.0021343

PMCID:: PMC3119701

Abstract Article PDF–3.9M

Select item 480416912.

Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals

Shuhei Nakamura, Özlem Karalay, Philipp S. Jäger, Makoto Horikawa, Corinna Klein, Kayo Nakamura, Christian Latza, Sven E. Templer, Christoph Dieterich, Adam Antebi

Nat Commun. 2016; 7: 10944. Published online 2016 Mar 22. doi: 10.1038/ncomms10944

PMCID:: PMC4804169

Abstract Article PDF–1.7M

Select item 872910713.

Regulation of fatty acid desaturase- and immunity gene-expression by mbk-1/DYRK1A in Caenorhabditis elegans

Hildegard I. D. Mack, Jennifer Kremer, Eva Albertini, Elisabeth K. M. Mack, Pidder Jansen-Dürr

BMC Genomics. 2022; 23: 25. Published online 2022 Jan 4. doi: 10.1186/s12864-021-08176-y

PMCID:: PMC8729107

Abstract Article PDF–1.6M

Select item 412234214.

A Functional Genomic Screen for Evolutionarily Conserved Genes Required for Lifespan and Immunity in Germline-Deficient C. elegans

Amit Sinha, Robbie Rae

PLoS One. 2014; 9(8): e101970. Published online 2014 Aug 5. doi: 10.1371/journal.pone.0101970

PMCID:: PMC4122342

Abstract Article PDF–1.2M

Select item 829171615.

Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans

Lidan Zeng, Xuesong Li, Christopher B. Preusch, Gary J. He, Ningyi Xu, Tom H. Cheung, Jianan Qu, Ho Yi Mak

PLoS Genet. 2021 Jul; 17(7): e1009635. Published online 2021 Jul 8. doi: 10.1371/journal.pgen.1009635

PMCID:: PMC8291716

Abstract Article PDF–6.1M

Select item 928341816.

Cabin1 domain-containing gene picd-1 interacts with pry-1/Axin to regulate multiple processes in Caenorhabditis elegans

Avijit Mallick, Shane K. B. Taylor, Sakshi Mehta, Bhagwati P. Gupta

Sci Rep. 2022; 12: 12029. Published online 2022 Jul 14. doi: 10.1038/s41598-022-15873-5

PMCID:: PMC9283418

Abstract Article PDF–3.5M

Select item 332519117.

Coordinate Regulation of Lipid Metabolism by Novel Nuclear Receptor Partnerships

Pranali P. Pathare, Alex Lin, Karin E. Bornfeldt, Stefan Taubert, Marc R. Van Gilst

PLoS Genet. 2012 Apr; 8(4): e1002645. Published online 2012 Apr 12. doi: 10.1371/journal.pgen.1002645

PMCID:: PMC3325191

Abstract Article PDF–1.3M

Select item 951484918.

H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans

Meng Huang, Minjie Hong, Xinhao Hou, Chengming Zhu, Di Chen, Xiangyang Chen, Shouhong Guang, Xuezhu Feng

eLife. 2022; 11: e74812. Published online 2022 Sep 20. doi: 10.7554/eLife.74812

PMCID:: PMC9514849

Abstract Article PDF–2.1M

Select item 705401219.

New Roles for the Heterochronic Transcription Factor LIN-29 in Cuticle Maintenance and Lipid Metabolism at the Larval-to-Adult Transition in Caenorhabditis elegans

Patricia Abete-Luzi, Tetsunari Fukushige, Sijung Yun, Michael W. Krause, David M. Eisenmann

Genetics. 2020 Mar; 214(3): 669–690. Published online 2020 Jan 23. doi: 10.1534/genetics.119.302860

PMCID:: PMC7054012

Abstract Article PDF–2.1M

Select item 988544020.

Intracellular lipid surveillance by small G protein geranylgeranylation

Abigail Watterson, Lexus Tatge, Naureen Wajahat, Sonja L. B. Arneaud, Rene Solano Fonseca, Shaghayegh T. Beheshti, Patrick Metang, Melina Mihelakis, Kielen R. Zuurbier, Chase D. Corley, Ishmael Dehghan, Jeffrey G. McDonald, Peter M. Douglas

Nature. Author manuscript; available in PMC 2023 Jan 30.

Published in final edited form as: Nature. 2022 May; 605(7911): 736–740. Published online 2022 May 18. doi: 10.1038/s41586-022-04729-7