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Select item 42225331.

Skelemin Association with α_IIbβ₃ Integrin: A Structural Model

Vitaliy Gorbatyuk, Khiem Nguyen, Nataly P. Podolnikova, Lalit Deshmukh, Xiaochen Lin, Tatiana P. Ugarova, Olga Vinogradova

Biochemistry. 2014 Nov 4; 53(43): 6766–6775. Published online 2014 Sep 15. doi: 10.1021/bi500680s

PMCID:: PMC4222533

Abstract Article PDF–5.1M

Select item 45403552.

Adhesion-Induced Unclasping of Cytoplasmic Tails of Integrin α_IIbβ₃

Nataly P. Podolnikova, Timothy E. O’Toole, Thomas A. Haas, Stephen C.-T. Lam, Joan E. B. Fox, Tatiana P. Ugarova

Biochemistry. Author manuscript; available in PMC 2015 Aug 18.

Published in final edited form as: Biochemistry. 2009 Jan 27; 48(3): 617–629. doi: 10.1021/bi801751s

PMCID:: PMC4540355

Abstract Article PDF–1.6M

Select item 21736153.

Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality

Kimberly L. Fritz-Six, Patrick R. Cox, Robert S. Fischer, Bisong Xu, Carol C. Gregorio, Huda Y. Zoghbi, Velia M. Fowler

J Cell Biol. 2003 Dec 8; 163(5): 1033–1044. doi: 10.1083/jcb.200308164

PMCID:: PMC2173615

Abstract Article PDF–2.7M

Select item 55672634.

Liprin-α-1 is a novel component of the murine neuromuscular junction and is involved in the organization of the postsynaptic machinery

Krzysztof M. Bernadzki, Marta Gawor, Marcin Pęziński, Paula Mazurek, Paweł Niewiadomski, Maria J. Rędowicz, Tomasz J. Prószyński

Sci Rep. 2017; 7: 9116. Published online 2017 Aug 22. doi: 10.1038/s41598-017-09590-7

PMCID:: PMC5567263

Abstract Article PDF–2.2M

Select item 110786445.

Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere

Chen Li, Derek T. Warren, Can Zhou, Shanelle De Silva, Darren G.S. Wilson, Mitla Garcia-Maya, Matthew A. Wheeler, Peter Meinke, Greta Sawyer, Elisabeth Ehler, Manfred Wehnert, Li Rao, Qiuping Zhang, Catherine M. Shanahan

J Biol Chem. 2024 May; 300(5): 107254. Published online 2024 Apr 2. doi: 10.1016/j.jbc.2024.107254

PMCID:: PMC11078644

Abstract Article PDF–4.4M

Select item 45994256.

Cypher and Enigma Homolog Protein Are Essential for Cardiac Development and Embryonic Survival

Yongxin Mu, Ran Jing, Angela K Peter, Stephan Lange, Lizhu Lin, Jianlin Zhang, Kunfu Ouyang, Xi Fang, Jennifer Veevers, Xinmin Zhou, Sylvia M Evans, Hongqiang Cheng, Ju Chen

J Am Heart Assoc. 2015 May; 4(5): e001950. Published online 2015 May 5. doi: 10.1161/JAHA.115.001950

Correction in:: J Am Heart Assoc. 2015 Jul; 4(7): e001930.

PMCID:: PMC4599425

Abstract Article PDF–1.4M

Select item 40312927.

Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo

Caroline R. McKeown, Roberta B. Nowak, David S. Gokhin, Velia M. Fowler

Dev Dyn. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Dev Dyn. 2014 Jun; 243(6): 800–817. Published online 2014 Feb 24. doi: 10.1002/dvdy.24115

PMCID:: PMC4031292

Abstract Article PDF–3.9M

Select item 27116088.

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

Shenhav Cohen, Jeffrey J. Brault, Steven P. Gygi, David J. Glass, David M. Valenzuela, Carlos Gartner, Esther Latres, Alfred L. Goldberg

J Cell Biol. 2009 Jun 15; 185(6): 1083–1095. doi: 10.1083/jcb.200901052

PMCID:: PMC2711608

Abstract Article PDF–1.9M

Select item 38712439.

Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia

Bing Zhang, Wenyuan Xiao, Hong Qiu, Fuming Zhang, Heather A. Moniz, Alexander Jaworski, Eduard Condac, Gerardo Gutierrez-Sanchez, Christian Heiss, Robin D. Clugston, Parastoo Azadi, John J. Greer, Carl Bergmann, Kelley W. Moremen, Dean Li, Robert J. Linhardt, Jeffrey D. Esko, Lianchun Wang

J Clin Invest. 2014 Jan 2; 124(1): 209–221. Published online 2013 Dec 20. doi: 10.1172/JCI71090

PMCID:: PMC3871243

Abstract Article PDF–8.0M

Select item 990782710.

Filamin C is Essential for mammalian myocardial integrity

Tongbin Wu, Yujun Xu, Lunfeng Zhang, Zhengyu Liang, Xiaohai Zhou, Sylvia M. Evans, Ju Chen

PLoS Genet. 2023 Jan; 19(1): e1010630. Published online 2023 Jan 27. doi: 10.1371/journal.pgen.1010630

PMCID:: PMC9907827

Abstract Article PDF–3.3M

Select item 258469911.

Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart

Zhiyv Niu, Dinakar Iyer, Simon J. Conway, James F. Martin, Kathryn Ivey, Deepak Srivastava, Alfred Nordheim, Robert J. Schwartz

Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46): 17824–17829. Published online 2008 Nov 12. doi: 10.1073/pnas.0805491105

PMCID:: PMC2584699

Abstract Article PDF–1.9M

Select item 206386512.

M line–deficient titin causes cardiac lethality through impaired maturation of the sarcomere

Stefanie Weinert, Nora Bergmann, Xiuju Luo, Bettina Erdmann, Michael Gotthardt

J Cell Biol. 2006 May 22; 173(4): 559–570. doi: 10.1083/jcb.200601014

PMCID:: PMC2063865

Abstract Article PDF–2.2M

Select item 848249913.

Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium

Xiaoli Zhang, Ze Wang, Qing Xu, Yuhan Chen, Wen Liu, Tong Zhong, Hongchang Li, Chengshi Quan, Lingqiang Zhang, Chun-Ping Cui

iScience. 2021 Oct 22; 24(10): 103097. Published online 2021 Sep 10. doi: 10.1016/j.isci.2021.103097

PMCID:: PMC8482499

Abstract Article PDF–5.1M

Select item 578552114.

Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease

Siyeon Rhee, Jae I. Chung, Devin A. King, Gaetano D’amato, David T. Paik, Anna Duan, Andrew Chang, Danielle Nagelberg, Bikram Sharma, Youngtae Jeong, Maximilian Diehn, Joseph C. Wu, Ashby J. Morrison, Kristy Red-Horse

Nat Commun. 2018; 9: 368. Published online 2018 Jan 25. doi: 10.1038/s41467-017-02796-3

PMCID:: PMC5785521

Abstract Article PDF–7.7M

Select item 505913915.

Calcium handling precedes cardiac differentiation to initiate the first heartbeat

Richard CV Tyser, Antonio MA Miranda, Chiann-mun Chen, Sean M Davidson, Shankar Srinivas, Paul R Riley

eLife. 2016; 5: e17113. Published online 2016 Oct 11. doi: 10.7554/eLife.17113

PMCID:: PMC5059139

Abstract Article PDF–6.8M

Select item 569259216.

HSPB7 is indispensable for heart development by modulating actin filament assembly

Tongbin Wu, Yongxin Mu, Julius Bogomolovas, Xi Fang, Jennifer Veevers, Roberta B. Nowak, Christopher T. Pappas, Carol C. Gregorio, Sylvia M. Evans, Velia M. Fowler, Ju Chen

Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): 11956–11961. Published online 2017 Oct 23. doi: 10.1073/pnas.1713763114

PMCID:: PMC5692592

Abstract Article PDF–1.1M

Select item 243107717.

Deletion of the Protein Kinase A/Protein Kinase G Target SMTNL1 Promotes an Exercise-adapted Phenotype in Vascular Smooth Muscle

Anne A. Wooldridge, Christopher N. Fortner, Beata Lontay, Takayuki Akimoto, Ronald L. Neppl, Carie Facemire, Michael B. Datto, Ashley Kwon, Everett McCook, Ping Li, Shiliang Wang, Randy J. Thresher, Sara E. Miller, Jean-Claude Perriard, Timothy P. Gavin, Robert C. Hickner, Thomas M. Coffman, Avril V. Somlyo, Zhen Yan, Timothy A. J. Haystead

J Biol Chem. 2008 Apr 25; 283(17): 11850–11859. doi: 10.1074/jbc.M708628200

PMCID:: PMC2431077

Abstract Article PDF–785K

Select item 285436718.

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology

David S. Gokhin, Raymond A. Lewis, Caroline R. McKeown, Roberta B. Nowak, Nancy E. Kim, Ryan S. Littlefield, Richard L. Lieber, Velia M. Fowler

J Cell Biol. 2010 Apr 5; 189(1): 95–109. doi: 10.1083/jcb.201001125

PMCID:: PMC2854367

Abstract Article PDF–4.2M

Select item 216918219.

Regulation of Skeletal Muscle Sarcomere Integrity and Postnatal Muscle Function by Mef2c

Matthew J. Potthoff, Michael A. Arnold, John McAnally, James A. Richardson, Rhonda Bassel-Duby, Eric N. Olson

Mol Cell Biol. 2007 Dec; 27(23): 8143–8151. Published online 2007 Sep 17. doi: 10.1128/MCB.01187-07

PMCID:: PMC2169182

Abstract Article PDF–774K

Select item 971882320.

DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal

Paola Cattaneo, Michael G. B. Hayes, Nina Baumgarten, Dennis Hecker, Sofia Peruzzo, Galip S. Aslan, Paolo Kunderfranco, Veronica Larcher, Lunfeng Zhang, Riccardo Contu, Gregory Fonseca, Simone Spinozzi, Ju Chen, Gianluigi Condorelli, Stefanie Dimmeler, Marcel H. Schulz, Sven Heinz, Nuno Guimarães-Camboa, Sylvia M. Evans

Nat Commun. 2022; 13: 7444. Published online 2022 Dec 2. doi: 10.1038/s41467-022-35070-2