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Select item 91794311.

Inhibition of ATR Reverses a Mitochondrial Respiratory Insufficiency

Megan B. Borror, Milena Girotti, Adwitiya Kar, Meghan K. Cain, Xiaoli Gao, Vivian L. MacKay, Brent Herron, Shylesh Bhaskaran, Sandra Becerra, Nathan Novy, Natascia Ventura, Thomas E. Johnson, Brian K. Kennedy, Shane L. Rea

Cells. 2022 Jun; 11(11): 1731. Published online 2022 May 24. doi: 10.3390/cells11111731

PMCID:: PMC9179431

Abstract Article PDF–4.5M

Select item 84153772.

Mutability of mononucleotide repeats, not oxidative stress, explains the discrepancy between laboratory-accumulated mutations and the natural allele-frequency spectrum in C. elegans

Moein Rajaei, Ayush Shekhar Saxena, Lindsay M. Johnson, Michael C. Snyder, Timothy A. Crombie, Robyn E. Tanny, Erik C. Andersen, Joanna Joyner-Matos, Charles F. Baer

Genome Res. 2021 Sep; 31(9): 1602–1613. doi: 10.1101/gr.275372.121

PMCID:: PMC8415377

Abstract Article PDF–3.8M

Select item 56293243.

Stress-Induced Sleep After Exposure to Ultraviolet Light Is Promoted by p53 in Caenorhabditis elegans

Hilary K. DeBardeleben, Lindsey E. Lopes, Mark P. Nessel, David M. Raizen

Genetics. 2017 Oct; 207(2): 571–582. Published online 2017 Jul 27. doi: 10.1534/genetics.117.300070

PMCID:: PMC5629324

Abstract Article PDF–1.2M

Select item 46474654.

Modeling of autosomal-dominant retinitis pigmentosa in Caenorhabditis elegans uncovers a nexus between global impaired functioning of certain splicing factors and cell type-specific apoptosis

Karinna Rubio-Peña, Laura Fontrodona, David Aristizábal-Corrales, Silvia Torres, Eric Cornes, Francisco J. García-Rodríguez, Xènia Serrat, David González-Knowles, Sylvain Foissac, Montserrat Porta-De-La-Riva, Julián Cerón

RNA. 2015 Dec; 21(12): 2119–2131. doi: 10.1261/rna.053397.115

PMCID:: PMC4647465

Abstract Article PDF–489K

Select item 65538205.

ATM and ATR Influence Meiotic Crossover Formation Through Antagonistic and Overlapping Functions in Caenorhabditis elegans

Wei Li, Judith L. Yanowitz

Genetics. 2019 Jun; 212(2): 431–443. Published online 2019 Apr 23. doi: 10.1534/genetics.119.302193

PMCID:: PMC6553820

Abstract Article PDF–2.1M

Select item 36106096.

CRL2^LRR-1 E3-Ligase Regulates Proliferation and Progression through Meiosis in the Caenorhabditis elegans Germline

Julien Burger, Jorge Merlet, Nicolas Tavernier, Bénédicte Richaudeau, Andreas Arnold, Rafal Ciosk, Bruce Bowerman, Lionel Pintard

PLoS Genet. 2013 Mar; 9(3): e1003375. Published online 2013 Mar 28. doi: 10.1371/journal.pgen.1003375

PMCID:: PMC3610609

Abstract Article PDF–13M

Select item 27918467.

The Caenorhabditis elegans Werner Syndrome Protein Functions Upstream of ATR and ATM in Response to DNA Replication Inhibition and Double-Strand DNA Breaks

Se-Jin Lee, Anton Gartner, Moonjung Hyun, Byungchan Ahn, Hyeon-Sook Koo

PLoS Genet. 2010 Jan; 6(1): e1000801. Published online 2010 Jan 8. doi: 10.1371/journal.pgen.1000801

PMCID:: PMC2791846

Abstract Article PDF–2.7M

Select item 25357188.

Maintenance of Mitochondrial DNA by the Caenorhabditis elegans ATR Checkpoint Protein ATL-1

Chihiro Mori, Takako Takanami, Atsushi Higashitani

Genetics. 2008 Sep; 180(1): 681–686. doi: 10.1534/genetics.108.090704

PMCID:: PMC2535718

Abstract Article PDF–847K

Select item 106589139.

THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans

Angelina Zheleva, Lola P. Camino, Nuria Fernández-Fernández, María García-Rubio, Peter Askjaer, Tatiana García-Muse, Andrés Aguilera

J Cell Sci. 2021 Oct 15; 134(20): jcs258435. Published online 2021 Oct 22. doi: 10.1242/jcs.258435

PMCID:: PMC10658913

Abstract Article

Select item 927895510.

Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity

Heyun Guo, Ericca L Stamper, Aya Sato-Carlton, Masa A Shimazoe, Xuan Li, Liangyu Zhang, Lewis Stevens, KC Jacky Tam, Abby F Dernburg, Peter M Carlton

eLife. 2022; 11: e77956. Published online 2022 Jun 27. doi: 10.7554/eLife.77956

PMCID:: PMC9278955

Abstract Article PDF–2.9M

Select item 419951611.

ZTF-8 Interacts with the 9-1-1 Complex and Is Required for DNA Damage Response and Double-Strand Break Repair in the C. elegans Germline

Hyun-Min Kim, Monica P. Colaiácovo

PLoS Genet. 2014 Oct; 10(10): e1004723. Published online 2014 Oct 16. doi: 10.1371/journal.pgen.1004723

PMCID:: PMC4199516

Abstract Article PDF–6.7M

Select item 146297112.

A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites

Jolanta Polanowska, Julie S Martin, Tatiana Garcia-Muse, Mark I R Petalcorin, Simon J Boulton

EMBO J. 2006 May 17; 25(10): 2178–2188. Published online 2006 Apr 20. doi: 10.1038/sj.emboj.7601102

PMCID:: PMC1462971

Abstract Article PDF–397K

Select item 506896213.

RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2^LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans

Batool Ossareh-Nazari, Anthi Katsiarimpa, Jorge Merlet, Lionel Pintard

G3 (Bethesda) 2016 Oct; 6(10): 3431–3442. Published online 2016 Aug 18. doi: 10.1534/g3.116.033043

PMCID:: PMC5068962

Abstract Article PDF–2.1M

Select item 225878614.

DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair

Jillian L. Youds, Louise J. Barber, Jordan D. Ward, Spencer J. Collis, Nigel J. O'Neil, Simon J. Boulton, Ann M. Rose

Mol Cell Biol. 2008 Mar; 28(5): 1470–1479. Published online 2007 Dec 17. doi: 10.1128/MCB.01641-07

PMCID:: PMC2258786

Abstract Article PDF–1.9M

Select item 964361315.

ATM/ATR kinases link the synaptonemal complex and DNA double-strand break repair pathway choice

Laura I. Láscarez-Lagunas, Saravanapriah Nadarajan, Marina Martinez-Garcia, Julianna Nicole Quinn, Elena Todisco, Tanuj Thakkar, Elizaveta Berson, Don Eaford, Oliver Crawley, Alex Montoya, Peter Faull, Nuria Ferrandiz, Consuelo Barroso, Sara Labella, Emily Koury, Sarit Smolikove, Monique Zetka, Enrique Martinez-Perez, Monica P. Colaiácovo

Curr Biol. Author manuscript; available in PMC 2023 Nov 7.

Published in final edited form as: Curr Biol. 2022 Nov 7; 32(21): 4719–4726.e4. Published online 2022 Sep 21. doi: 10.1016/j.cub.2022.08.081