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Items: 11

1.
The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity
Joshua Wollam, Lilia Magomedova, Daniel B Magner, Yidong Shen, Veerle Rottiers, Daniel L Motola, David J Mangelsdorf, Carolyn L Cummins, Adam Antebi
Aging Cell. Author manuscript; available in PMC 2014 Feb 3.
Published in final edited form as: Aging Cell. 2011 Oct; 10(5): 879–884. Published online 2011 Aug 7. doi: 10.1111/j.1474-9726.2011.00733.x
PMCID:
PMC3909771
AbstractArticlePDF–1.4M
2.
Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor regulating C. elegans development and lifespan
Parag Mahanti, Neelanjan Bose, Axel Bethke, Joshua C. Judkins, Joshua Wollam, Kathleen J. Dumas, Anna M. Zimmerman, Sydney L. Campbell, Patrick J. Hu, Adam Antebi, Frank C. Schroeder
Cell Metab. Author manuscript; available in PMC 2015 Jan 7.
Published in final edited form as: Cell Metab. 2014 Jan 7; 19(1): 73–83. doi: 10.1016/j.cmet.2013.11.024
PMCID:
PMC3924769
AbstractArticlePDF–2.0M
3.
Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis
Zhu Wang, Mi Cheong Cheong, Jet Tsien, Heping Deng, Tian Qin, Jonathan DC Stoltzfus, Tegegn G Jaleta, Xinshe Li, James B Lok, Steven A Kliewer, David J Mangelsdorf
eLife. 2021; 10: e73535. Published online 2021 Dec 7. doi: 10.7554/eLife.73535
PMCID:
PMC8651287
AbstractArticlePDF–4.2M
4.
Filarial DAF-12 sense the host serum to resume iL3 development during infection
Rémy Bétous, Anthony Emile, Hua Che, Eva Guchen, Didier Concordet, Thavy Long, Sandra Noack, Paul M. Selzer, Roger Prichard, Anne Lespine
PLoS Pathog. 2023 Jun; 19(6): e1011462. Published online 2023 Jun 20. doi: 10.1371/journal.ppat.1011462
PMCID:
PMC10313052
AbstractArticlePDF–2.1M
5.
dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest
Rebecca E. W. Kaplan, Yutao Chen, Brad T. Moore, James M. Jordan, Colin S. Maxwell, Adam J. Schindler, L. Ryan Baugh
PLoS Genet. 2015 Dec; 11(12): e1005731. Published online 2015 Dec 11. doi: 10.1371/journal.pgen.1005731
PMCID:
PMC4676721
AbstractArticlePDF–2.7M
6.
Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases
Mercedes M. Pérez-Jiménez, José M. Monje-Moreno, Ana María Brokate-Llanos, Mónica Venegas-Calerón, Alicia Sánchez-García, Paula Sansigre, Amador Valladares, Sara Esteban-García, Irene Suárez-Pereira, Javier Vitorica, José Julián Ríos, Marta Artal-Sanz, Ángel M. Carrión, Manuel J. Muñoz
Nat Commun. 2021; 12: 49. Published online 2021 Jan 4. doi: 10.1038/s41467-020-20269-y
PMCID:
PMC7782729
AbstractArticlePDF–1.7M
7.
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling
Birgit Gerisch, Veerle Rottiers, Dongling Li, Daniel L. Motola, Carolyn L. Cummins, Hans Lehrach, David J. Mangelsdorf, Adam Antebi
Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12): 5014–5019. Published online 2007 Mar 14. doi: 10.1073/pnas.0700847104
PMCID:
PMC1821127
AbstractArticlePDF–913K
8.
Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan
Kathleen J. Dumas, Chunfang Guo, Xi Wang, Kirk B. Burkhart, Elizabeth J. Adams, Hena Alam, Patrick J. Hu
Dev Biol. Author manuscript; available in PMC 2015 Jul 22.
Published in final edited form as: Dev Biol. 2010 Apr 15; 340(2): 605–612. Published online 2010 Feb 21. doi: 10.1016/j.ydbio.2010.02.022
PMCID:
PMC4511482
AbstractArticlePDF–650K
9.
Determining Toxic Potencies of Water-Soluble Contaminants in Wastewater Influents and Effluent Using Gene Expression Profiling in C. elegans as a Bioanalytical Tool
Antoine Karengera, Ilse Verburg, Mark G. Sterken, Joost A. G. Riksen, Albertinka J. Murk, Inez J. T. Dinkla
Arch Environ Contam Toxicol. 2022; 83(3): 284–294. Published online 2022 Oct 3. doi: 10.1007/s00244-022-00959-y
PMCID:
PMC9556352
AbstractArticlePDF–1.4M
10.
C. elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity
Yanmei Zhang, Jinling Xu, Cristina Puscau, Yongsoon Kim, Xi Wang, Hena Alam, Patrick J. Hu
Dev Biol. Author manuscript; available in PMC 2009 Mar 15.
Published in final edited form as: Dev Biol. 2008 Mar 15; 315(2): 290–302. Published online 2008 Jan 3. doi: 10.1016/j.ydbio.2007.12.032
PMCID:
PMC2350227
AbstractArticlePDF–2.1M
11.
EAK-7 controls development and lifespan by regulating nuclear DAF-16/FoxO activity
Hena Alam, Travis W. Williams, Kathleen J. Dumas, Chunfang Guo, Sawako Yoshina, Shohei Mitani, Patrick J. Hu
Cell Metab. Author manuscript; available in PMC 2011 Jul 4.
Published in final edited form as: Cell Metab. 2010 Jul 4; 12(1): 30–41. doi: 10.1016/j.cmet.2010.05.004
PMCID:
PMC2907918
AbstractArticlePDF–2.7M

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