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Select item 107001071.

Matching variants for functional characterization of genetic variants

Sebiha Cevik, Pei Zhao, Atiyye Zorluer, Mustafa S Pir, Wenyin Bian, Oktay I Kaplan

G3 (Bethesda) 2023 Dec; 13(12): jkad227. Published online 2023 Nov 2. doi: 10.1093/g3journal/jkad227

PMCID:: PMC10700107

Abstract Article PDF–3.5M

Select item 24089262.

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

Erica D Smith, Tammi L Kaeberlein, Brynn T Lydum, Jennifer Sager, K Linnea Welton, Brian K Kennedy, Matt Kaeberlein

BMC Dev Biol. 2008; 8: 49. Published online 2008 May 5. doi: 10.1186/1471-213X-8-49

PMCID:: PMC2408926

Abstract Article PDF–501K

Select item 49921403.

The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate

Qing Wei, Yingyi Zhang, Clementine Schouteden, Yuxia Zhang, Qing Zhang, Jinhong Dong, Veronika Wonesch, Kun Ling, Alexander Dammermann, Jinghua Hu

Nat Commun. 2016; 7: 12437. Published online 2016 Aug 18. doi: 10.1038/ncomms12437

PMCID:: PMC4992140

Abstract Article PDF–2.4M

Select item 99580704.

Microfluidics and fluorescence microscopy protocol to study the response of C. elegans to chemosensory stimuli

Christine W. Bruggeman, Guus H. Haasnoot, Erwin J.G. Peterman

STAR Protoc. 2023 Mar 17; 4(1): 102121. Published online 2023 Feb 14. doi: 10.1016/j.xpro.2023.102121

PMCID:: PMC9958070

Abstract Article PDF–2.8M

Select item 22483445.

The Conserved Proteins CHE-12 and DYF-11 Are Required for Sensory Cilium Function in Caenorhabditis elegans

Taulant Bacaj, Yun Lu, Shai Shaham

Genetics. 2008 Feb; 178(2): 989–1002. doi: 10.1534/genetics.107.082453

PMCID:: PMC2248344

Abstract Article PDF–2.3M

Select item 18553666.

Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans

Jan Burghoorn, Martijn P. J. Dekkers, Suzanne Rademakers, Ton de Jong, Rob Willemsen, Gert Jansen

Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17): 7157–7162. Published online 2007 Apr 9. doi: 10.1073/pnas.0606974104

PMCID:: PMC1855366

Abstract Article PDF–1.0M

Select item 1650977.

XBX-1 Encodes a Dynein Light Intermediate Chain Required for Retrograde Intraflagellar Transport and Cilia Assembly in Caenorhabditis elegans

Jenny C. Schafer, Courtney J. Haycraft, James H. Thomas, Bradley K. Yoder, Peter Swoboda

Mol Biol Cell. 2003 May; 14(5): 2057–2070. doi: 10.1091/mbc.E02-10-0677

PMCID:: PMC165097

Abstract Article PDF–565K

Select item 16353798.

Caenorhabditis elegans DYF-2, an Orthologue of Human WDR19, Is a Component of the Intraflagellar Transport Machinery in Sensory Cilia

Evgeni Efimenko, Oliver E. Blacque, Guangshuo Ou, Courtney J. Haycraft, Bradley K. Yoder, Jonathan M. Scholey, Michel R. Leroux, Peter Swoboda

Mol Biol Cell. 2006 Nov; 17(11): 4801–4811. doi: 10.1091/mbc.E06-04-0260

PMCID:: PMC1635379

Abstract Article PDF–1.0M

Select item 4435249.

Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport

Oliver E. Blacque, Michael J. Reardon, Chunmei Li, Jonathan McCarthy, Moe R. Mahjoub, Stephen J. Ansley, Jose L. Badano, Allan K. Mah, Philip L. Beales, William S. Davidson, Robert C. Johnsen, Mark Audeh, Ronald H.A. Plasterk, David L. Baillie, Nicholas Katsanis, Lynne M. Quarmby, Stephen R. Wicks, Michel R. Leroux

Genes Dev. 2004 Jul 1; 18(13): 1630–1642. doi: 10.1101/gad.1194004

PMCID:: PMC443524

Abstract Article PDF–327K

Select item 167967210.

The WD Repeat-containing Protein IFTA-1 Is Required for Retrograde Intraflagellar Transport

Oliver E. Blacque, Chunmei Li, Peter N. Inglis, Muneer A. Esmail, Guangshuo Ou, Allan K. Mah, David L. Baillie, Jonathan M. Scholey, Michel R. Leroux

Mol Biol Cell. 2006 Dec; 17(12): 5053–5062. doi: 10.1091/mbc.E06-06-0571

PMCID:: PMC1679672

Abstract Article PDF–1.3M

Select item 189476211.

Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans

Saikat Mukhopadhyay, Yun Lu, Hongmin Qin, Anne Lanjuin, Shai Shaham, Piali Sengupta

EMBO J. 2007 Jun 20; 26(12): 2966–2980. Published online 2007 May 17. doi: 10.1038/sj.emboj.7601717

PMCID:: PMC1894762

Abstract Article PDF–514K

Select item 120557912.

Evidence for Parallel Processing of Sensory Information Controlling Dauer Formation in Caenorhabditis Elegans

J. H. Thomas, D. A. Birnby, J. J. Vowels

Genetics. 1993 Aug; 134(4): 1105–1117. doi: 10.1093/genetics/134.4.1105

PMCID:: PMC1205579

Summary PDF–2.2M

Select item 1039329613.

Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans

Rebeca Brocal-Ruiz, Ainara Esteve-Serrano, Carlos Mora-Martínez, Maria Luisa Franco-Rivadeneira, Peter Swoboda, Juan J Tena, Marçal Vilar, Nuria Flames

eLife. 2023; 12: e89702. Published online 2023 Jul 14. doi: 10.7554/eLife.89702

PMCID:: PMC10393296

Abstract Article PDF–10M

Select item 797975014.

The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing

Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen

Nat Commun. 2021; 12: 1789. Published online 2021 Mar 19. doi: 10.1038/s41467-021-22065-8

PMCID:: PMC7979750

Abstract Article PDF–4.2M

Select item 227572315.

Dietary regulation of hypodermal polyploidization in C. elegans

Luke S Tain, Encarnación Lozano, Alberto G Sáez, Armand M Leroi

BMC Dev Biol. 2008; 8: 28. Published online 2008 Mar 12. doi: 10.1186/1471-213X-8-28

PMCID:: PMC2275723

Abstract Article PDF–345K

Select item 226540616.

The Caenorhabditis elegans nephrocystins act as global modifiers of cilium structure

Andrew R. Jauregui, Ken C.Q. Nguyen, David H. Hall, Maureen M. Barr

J Cell Biol. 2008 Mar 10; 180(5): 973–988. doi: 10.1083/jcb.200707090

PMCID:: PMC2265406

Abstract Article PDF–4.6M

Select item 306314717.

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

Corey L. Williams, Chunmei Li, Katarzyna Kida, Peter N. Inglis, Swetha Mohan, Lucie Semenec, Nathan J. Bialas, Rachel M. Stupay, Nansheng Chen, Oliver E. Blacque, Bradley K. Yoder, Michel R. Leroux

J Cell Biol. 2011 Mar 21; 192(6): 1023–1041. doi: 10.1083/jcb.201012116

PMCID:: PMC3063147

Abstract Article PDF–6.2M

Select item 272091818.

Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins

Nathan J. Bialas, Peter N. Inglis, Chunmei Li, Jon F. Robinson, Jeremy D. K. Parker, Michael P. Healey, Erica E. Davis, Chrystal D. Inglis, Tiina Toivonen, David C. Cottell, Oliver E. Blacque, Lynne M. Quarmby, Nicholas Katsanis, Michel R. Leroux

J Cell Sci. 2009 Mar 1; 122(5): 611–624. Published online 2009 Feb 10. doi: 10.1242/jcs.028621

PMCID:: PMC2720918

Abstract Article

Select item 857687119.

WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing

Ana R.G. De-Castro, Diogo R.M. Rodrigues, Maria J.G. De-Castro, Neide Vieira, Cármen Vieira, Ana X. Carvalho, Reto Gassmann, Carla M.C. Abreu, Tiago J. Dantas

J Cell Biol. 2022 Jan 3; 221(1): e202010178. Published online 2021 Nov 5. doi: 10.1083/jcb.202010178

PMCID:: PMC8576871

Abstract Article PDF–8.1M

Select item 514514420.

Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport

Victor L. Jensen, Stephen Carter, Anna A. W. M. Sanders, Chunmei Li, Julie Kennedy, Tiffany A. Timbers, Jerry Cai, Noemie Scheidel, Breandán N. Kennedy, Ryan D. Morin, Michel R. Leroux, Oliver E. Blacque

PLoS Genet. 2016 Dec; 12(12): e1006469. Published online 2016 Dec 8. doi: 10.1371/journal.pgen.1006469