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Select item 63550771.

Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function

Deok Hwa Nam, Eunah Kim, Ashley Benham, Hye-Kyung Park, Benjamin Soibam, George E. Taffet, Jason T. Kaelber, Ji Ho Suh, Heinrich Taegtmeyer, Mark L. Entman, Erin L. Reineke

FASEB J. 2019 Jan; 33(1): 711–721. Published online 2018 Jul 19. doi: 10.1096/fj.201800602R

PMCID:: PMC6355077

Abstract Article

Select item 46407752.

SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis

Tiffany Fleet, Bin Zhang, Fumin Lin, Bokai Zhu, Subhamoy Dasgupta, Erin Stashi, Bryan Tackett, Sundararajah Thevananther, Kimal I. Rajapakshe, Naomi Gonzales, Adam Dean, Jianqiang Mao, Nikolai Timchenko, Anna Malovannaya, Jun Qin, Cristian Coarfa, Francesco DeMayo, Clifford C. Dacso, Charles E. Foulds, Bert W. O’Malley, Brian York

Proc Natl Acad Sci U S A. 2015 Nov 3; 112(44): E6068–E6077. Published online 2015 Oct 20. doi: 10.1073/pnas.1519073112

PMCID:: PMC4640775

Abstract Article PDF–3.0M

Select item 35340273.

SRC-2 Coactivator Deficiency Decreases Functional Reserve in Response to Pressure Overload of Mouse Heart

Erin L. Reineke, Brian York, Erin Stashi, Xian Chen, Anna Tsimelzon, Jianming Xu, Christopher B. Newgard, George E. Taffet, Heinrich Taegtmeyer, Mark L. Entman, Bert W. O’Malley

PLoS One. 2012; 7(12): e53395. Published online 2012 Dec 31. doi: 10.1371/journal.pone.0053395

PMCID:: PMC3534027

Abstract Article PDF–1.2M

Select item 34068274.

Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids

Yurii Chinenov, Rebecca Gupte, Jana Dobrovolna, Jamie R. Flammer, Bill Liu, Francesco E. Michelassi, Inez Rogatsky

Proc Natl Acad Sci U S A. 2012 Jul 17; 109(29): 11776–11781. Published online 2012 Jul 2. doi: 10.1073/pnas.1206059109

PMCID:: PMC3406827

Abstract Article PDF–862K

Select item 27071925.

Skeletal Consequences of Deletion of Steroid Receptor Coactivator-2/Transcription Intermediary Factor-2

Ulrike I. Mödder, David G. Monroe, Daniel G. Fraser, Thomas C. Spelsberg, Clifford J. Rosen, Martine Géhin, Pierre Chambon, Bert W. O'Malley, Sundeep Khosla

J Biol Chem. 2009 Jul 10; 284(28): 18767–18777. Published online 2009 May 7. doi: 10.1074/jbc.M109.000836

PMCID:: PMC2707192

Abstract Article PDF–3.9M

Select item 105921876.

Ncoa2 promotes CD8⁺ T cell-mediated anti-tumor immunity by stimulating T-cell activation via upregulation of PGC-1α critical for mitochondrial function: Noca2 in CD8+ T-cell activation and antitumor response

Xiancai Zhong, Hongmin Wu, Ching Ouyang, Wencan Zhang, Yun Shi, Yi-Chang Wang, David K. Ann, Yousang Gwack, Weirong Shang, Zuoming Sun

Cancer Immunol Res. Author manuscript; available in PMC 2024 Apr 4.

Published in final edited form as: Cancer Immunol Res. 2023 Oct 4; 11(10): 1414–1431. doi: 10.1158/2326-6066.CIR-23-0092

PMCID:: PMC10592187

Abstract Article PDF–2.4M

Select item 103226897.

HEY1-NCOA2 expression modulates chondrogenic differentiation and induces mesenchymal chondrosarcoma in mice

Miwa Tanaka, Mizuki Homme, Yasuyo Teramura, Kohei Kumegawa, Yukari Yamazaki, Kyoko Yamashita, Motomi Osato, Reo Maruyama, Takuro Nakamura

JCI Insight. 2023 May 22; 8(10): e160279. Published online 2023 May 22. doi: 10.1172/jci.insight.160279

PMCID:: PMC10322689

Abstract Article PDF–16M

Select item 87156768.

Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition

Yongjie Yang, Yanlin He, Hailan Liu, Wenjun Zhou, Chunmei Wang, Pingwen Xu, Xing Cai, Hesong Liu, Kaifan Yu, Zhou Pei, Ilirjana Hyseni, Makoto Fukuda, Qingchun Tong, Jianming Xu, Zheng Sun, Bert W. O’Malley, Yong Xu

Cell Rep. Author manuscript; available in PMC 2021 Dec 29.

Published in final edited form as: Cell Rep. 2021 Dec 7; 37(10): 110075. doi: 10.1016/j.celrep.2021.110075

PMCID:: PMC8715676

Abstract Article PDF–1.5M

Select item 75554129.

Transcription cofactor GRIP1 differentially affects myeloid cell–driven neuroinflammation and response to IFN-β therapy

Sanda Mimouna, David A. Rollins, Gayathri Shibu, Bowranigan Tharmalingam, Dinesh K. Deochand, Xi Chen, David Oliver, Yurii Chinenov, Inez Rogatsky

J Exp Med. 2021 Jan 4; 218(1): e20192386. Published online 2020 Oct 12. doi: 10.1084/jem.20192386

Correction in:: J Exp Med. 2021 Jan 4; 218(1): jem.2019238611162020C.

PMCID:: PMC7555412

Abstract Article PDF–5.7M

Select item 576696110.

Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload–induced angiogenesis

Ji Ho Suh, Li Lai, Deokhwa Nam, Jong Kim, Juyeon Jo, George E. Taffet, Eunah Kim, Jason T. Kaelber, Hyun-Kyoung Lee, Mark L. Entman, John P. Cooke, Erin L. Reineke

J Biol Chem. 2017 Dec 29; 292(52): 21643–21652. Published online 2017 Nov 10. doi: 10.1074/jbc.M117.804740

PMCID:: PMC5766961

Abstract Article PDF–2.4M

Select item 524893111.

Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology

Tiffany Fleet, Erin Stashi, Bokai Zhu, Kimal Rajapakshe, Kathrina L. Marcelo, Nicole M. Kettner, Blythe K. Gorman, Cristian Coarfa, Loning Fu, Bert W. O’Malley, Brian York

J Biol Rhythms. Author manuscript; available in PMC 2017 Jan 20.

Published in final edited form as: J Biol Rhythms. 2016 Oct; 31(5): 443–460. Published online 2016 Jul 17. doi: 10.1177/0748730416657921

PMCID:: PMC5248931

Abstract Article PDF–2.7M

Select item 497448012.

The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis

Maddalena Coppo, Yurii Chinenov, Maria A. Sacta, Inez Rogatsky

Nat Commun. 2016; 7: 12254. Published online 2016 Jul 28. doi: 10.1038/ncomms12254

PMCID:: PMC4974480

Abstract Article PDF–1.4M

Select item 481944713.

Expression of the MOZ-TIF2 oncoprotein in mice represses senescence

Anne Largeot, Flor Maria Perez-Campo, Elli Marinopoulou, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud

Exp Hematol. 2016 Apr; 44(4): 231–237.e4. doi: 10.1016/j.exphem.2015.12.006

PMCID:: PMC4819447

Abstract Article

Select item 467183514.

Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading

Bokai Zhu, Leah A. Gates, Erin Stashi, Subhamoy Dasgupta, Naomi Gonzales, Adam Dean, Clifford C. Dacso, Brian York, Bert W. O’Malley

Mol Cell. Author manuscript; available in PMC 2016 Dec 3.

Published in final edited form as: Mol Cell. 2015 Dec 3; 60(5): 769–783. Published online 2015 Nov 21. doi: 10.1016/j.molcel.2015.10.024

PMCID:: PMC4671835

Abstract Article PDF–3.4M

Select item 417962615.

Hepatic SRC-1 Activity Orchestrates Transcriptional Circuitries of Amino Acid Pathways with Potential Relevance for Human Metabolic Pathogenesis

Mounia Tannour-Louet, Brian York, Ke Tang, Erin Stashi, Hichem Bouguerra, Suoling Zhou, Hui Yu, Lee-Jun C. Wong, Robert D. Stevens, Jianming Xu, Christopher B. Newgard, Bert W. O'Malley, Jean-Francois Louet

Mol Endocrinol. 2014 Oct; 28(10): 1707–1718. Published online 2014 Aug 22. doi: 10.1210/me.2014-1083

PMCID:: PMC4179626

Abstract Article

Select item 364084616.

Insights into Negative Regulation by the Glucocorticoid Receptor from Genome-Wide Profiling of Inflammatory Cistromes

N. Henriette Uhlenhaut, Grant D. Barish, Ruth T. Yu, Michael Downes, Malith Karunasiri, Christopher Liddle, Petra Schwalie, Norbert Hübner, Ronald M. Evans

Mol Cell. Author manuscript; available in PMC 2013 Jul 10.

Published in final edited form as: Mol Cell. 2013 Jan 10; 49(1): 158–171. Published online 2012 Nov 15. doi: 10.1016/j.molcel.2012.10.013

PMCID:: PMC3640846

Abstract Article PDF–2.2M

Select item 271222417.

Foxa2-dependent hepatic gene regulatory networks depend on physiological state

Irina M. Bochkis, Jonathan Schug, Nir E. Rubins, Atul R. Chopra, Bert W. O'Malley, Klaus H. Kaestner

Physiol Genomics. 2009 Jul; 38(2): 186–195. Published online 2009 May 5. doi: 10.1152/physiolgenomics.90376.2008

PMCID:: PMC2712224

Abstract Article

Select item 212132118.

Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: insights from the mouse, relevance to the human

Atish Mukherjee, Paula Amato, D. Craig Allred, Francesco J. DeMayo, John P. Lydon

Nucl Recept Signal. 2007; 5: e011. Published online 2007 Nov 30. doi: 10.1621/nrs.05011

PMCID:: PMC2121321

Abstract Article PDF–8.1M

Select item 38476819.

Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction

Manuel Mark, Hiromi Yoshida-Komiya, Martine Gehin, Lan Liao, Ming-Jer Tsai, Bert W. O'Malley, Pierre Chambon, Jianming Xu

Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13): 4453–4458. doi: 10.1073/pnas.0400234101

PMCID:: PMC384768

Abstract Article PDF–663K

Select item 716536420.

SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα

Shoshana Naiman, Frank K. Huynh, Reuven Gil, Yair Glick, Yael Shahar, Noga Touitou, Liat Nahum, Matan Y. Avivi, Asael Roichman, Yariv Kanfi, Asaf A. Gertler, Tirza Doniger, Olga R. Ilkayeva, Ifat Abramovich, Orly Yaron, Batia Lerrer, Eyal Gottlieb, Robert A. Harris, Doron Gerber, Matthew D. Hirschey, Haim Y. Cohen

Cell Rep. Author manuscript; available in PMC 2020 Apr 18.

Published in final edited form as: Cell Rep. 2019 Dec 17; 29(12): 4127–4143.e8. doi: 10.1016/j.celrep.2019.11.067