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Select item 95095661.

A novel 2B4 receptor leads to worse pregnancy outcomes by facilitating TNF-α and IFN-γ production in dNK cells during Toxoplasma gondii infection

Xiaoyan Xu, Guangmei Zheng, Yushan Ren, Xiaohua He, Biwen Peng, Xuemei Hu, Wanhong Liu

Parasit Vectors. 2022; 15: 337. Published online 2022 Sep 24. doi: 10.1186/s13071-022-05455-9

PMCID:: PMC9509566

Abstract Article PDF–6.5M

Select item 70948712.

Sepsis Erodes CD8⁺ Memory T Cell Protective Immunity Against an EBV Homolog in a 2B4-Dependent Manner

J Xie, RL Crepeau, CW Chen, W Zhang, S Otani, CM Coopersmith, ML Ford

J Leukoc Biol. Author manuscript; available in PMC 2020 Mar 25.

Published in final edited form as: J Leukoc Biol. 2019 Mar; 105(3): 565–575. Published online 2019 Jan 9. doi: 10.1002/JLB.4A0718-292R

PMCID:: PMC7094871

Abstract Article PDF–955K

Select item 61038053.

2B4 Mediates Inhibition of CD8⁺ T Cell Responses via Attenuation of Glycolysis and Cell Division

Sonia J. Laurie, Danya Liu, Maylene E. Wagener, Phoebe E. Stark, Cox Terhorst, Mandy L. Ford

J Immunol. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: J Immunol. 2018 Sep 1; 201(5): 1536–1548. Published online 2018 Jul 16. doi: 10.4049/jimmunol.1701240

PMCID:: PMC6103805

Abstract Article PDF–977K

Select item 45549874.

2B4 Is Dispensable for T-Dependent B Cell Immune Responses, but Its Deficiency Leads to Enhanced T-Independent Responses Due to an Increase in Peritoneal Cavity B1b Cells

Avijit Ray, Cheng-Yin Yuan, Nichole M. Miller, Hong Mei, Bonnie N. Dittel

PLoS One. 2015; 10(8): e0137314. Published online 2015 Aug 31. doi: 10.1371/journal.pone.0137314

PMCID:: PMC4554987

Abstract Article PDF–989K

Select item 44767295.

Inhibition of Donor-Reactive CD8+ T Cell Responses by Selective CD28 Blockade Is Independent of Reduced ICOS Expression

Danya Liu, Suzanne J. Suchard, Steve G. Nadler, Mandy L. Ford

PLoS One. 2015; 10(6): e0130490. Published online 2015 Jun 22. doi: 10.1371/journal.pone.0130490

PMCID:: PMC4476729

Abstract Article PDF–2.9M

Select item 44095166.

SLAMF4 is a Negative Regulator of Expansion of Cytotoxic Intra-epithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine

Michael S. O’Keeffe, Joo-Hye Song, Gongxian Liao, Jaime De Calisto, Peter J. Halibozek, J. Rodrigo Mora, Atul K. Bhan, Ninghai Wang, Hans-Christian Reinecker, Cox Terhorst

Gastroenterology. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Gastroenterology. 2015 May; 148(5): 991–1001.e4. Published online 2015 Feb 10. doi: 10.1053/j.gastro.2015.02.003

PMCID:: PMC4409516

Abstract Article PDF–1.9M

Select item 42566687.

Homotypic NK cell-to-cell communication controls cytokine responsiveness of innate immune NK cells

Tae-Jin Kim, Miju Kim, Hye Mi Kim, Seon Ah Lim, Eun-Ok Kim, Kwanghee Kim, Kwang Hoon Song, Jiyoung Kim, Vinay Kumar, Cassian Yee, Junsang Doh, Kyung-Mi Lee

Sci Rep. 2014; 4: 7157. Published online 2014 Dec 5. doi: 10.1038/srep07157

PMCID:: PMC4256668

Abstract Article PDF–2.4M

Select item 32419828.

Tight Regulation of Memory CD8 T Cells Limits Their Effectiveness during Sustained High Viral Load

Erin E. West, Ben Youngblood, Wendy G. Tan, Hyun-Tak Jin, Koichi Araki, Gabriela Alexe, Bogumila T. Konieczny, Silvia Calpe, Gordon J. Freeman, Cox Terhorst, W. Nicholas Haining, Rafi Ahmed

Immunity. Author manuscript; available in PMC 2012 Aug 26.

Published in final edited form as: Immunity. 2011 Aug 26; 35(2): 285–298. doi: 10.1016/j.immuni.2011.05.017

PMCID:: PMC3241982

Abstract Article PDF–3.3M

Select item 31197279.

An NK cell-independent role for slamf4 in controlling humoral Autoimmunity

Daniel R Brown, Silvia Calpe, Marton Keszei, Ninghai Wang, Shannon McArdel, Cox Terhorst, Arlene H Sharpe

J Immunol. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: J Immunol. 2011 Jul 1; 187(1): 21–25. Published online 2011 May 27. doi: 10.4049/jimmunol.1100510

PMCID:: PMC3119727

Abstract Article PDF–1.5M

Select item 221190210.

2B4 Acts As a Non–Major Histocompatibility Complex Binding Inhibitory Receptor on Mouse Natural Killer Cells

Kyung-Mi Lee, Megan E. McNerney, Susan E. Stepp, Porunelloor A. Mathew, John D. Schatzle, Michael Bennett, Vinay Kumar

J Exp Med. 2004 May 3; 199(9): 1245–1254. doi: 10.1084/jem.20031989

PMCID:: PMC2211902

Abstract Article PDF–181K

Select item 694885411.

2B4 but not PD-1 blockade improves mortality in septic animals with preexisting malignancy

Ching-wen Chen, Ming Xue, Wenxiao Zhang, Jianfeng Xie, Craig M. Coopersmith, Mandy L. Ford

JCI Insight. 2019 Nov 14; 4(22): e127867. Published online 2019 Nov 14. doi: 10.1172/jci.insight.127867

PMCID:: PMC6948854

Abstract Article PDF–12M

Select item 653836012.

Increased attrition of memory T cells during sepsis requires 2B4

Jianfeng Xie, Ching-wen Chen, Yini Sun, Sonia J. Laurie, Wenxiao Zhang, Shunsuke Otani, Gregory S. Martin, Craig M. Coopersmith, Mandy L. Ford

JCI Insight. 2019 May 2; 4(9): e126030. Published online 2019 May 2. doi: 10.1172/jci.insight.126030

PMCID:: PMC6538360

Abstract Article PDF–2.2M

Select item 392056513.

2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8⁺ T cell responses

Danya Liu, Scott M. Krummey, I. Raul Badell, Maylene Wagener, Lumelle A. Schneeweis, Dawn K. Stetsko, Suzanne J. Suchard, Steven G. Nadler, Mandy L. Ford

J Exp Med. 2014 Feb 10; 211(2): 297–311. doi: 10.1084/jem.20130902