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Items: 1 to 20 of 319

1.
Notch2 with retinoic acid license IL-23 expression by intestinal EpCAM+ DCIR2+ cDC2s in mice
Daiya Ohara, Yusuke Takeuchi, Hitomi Watanabe, Yoonha Lee, Hiroki Mukoyama, Toshiaki Ohteki, Gen Kondoh, Keiji Hirota
J Exp Med. 2024 Feb 5; 221(2): e20230923. Published online 2024 Jan 5. doi: 10.1084/jem.20230923
PMCID:
PMC10770806
AbstractArticlePDF–8.3M
2.
Fracture healing in a mouse model of Hajdu–Cheney-Syndrome with high turnover osteopenia results in decreased biomechanical stability
Tobias Malte Ballhause, Shan Jiang, Weixin Xie, Jan Sevecke, Christine Dowling, Tobias Dust, Sabine Brandt, Peter R. Mertens, Timur Alexander Yorgan, Thorsten Schinke, Karl-Heinz Frosch, Anke Baranowsky, Johannes Keller
Sci Rep. 2023; 13: 11418. Published online 2023 Jul 14. doi: 10.1038/s41598-023-38638-0
PMCID:
PMC10349118
AbstractArticlePDF–2.6M
3.
Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease
Qiong Liu, Kailin Zhang, Yunhee Kang, Yangping Li, Penghui Deng, Yujing Li, Yun Tian, Qiying Sun, Yu Tang, Keqin Xu, Yao Zhou, Jun-Ling Wang, Jifeng Guo, Jia-Da Li, Kun Xia, Qingtuan Meng, Emily G. Allen, Zhexing Wen, Ziyi Li, Hong Jiang, Lu Shen, Ranhui Duan, Bing Yao, Beisha Tang, Peng Jin, Yongcheng Pan
Sci Adv. 2022 Nov; 8(47): eadd6391. Published online 2022 Nov 23. doi: 10.1126/sciadv.add6391
PMCID:
PMC9683706
AbstractArticlePDF–4.1M
4.
Smooth muscle cell Notch2 is not required for atherosclerotic plaque formation in ApoE null mice
Jessica Davis-Knowlton, Jacqueline E. Turner, Anne Harrington, Lucy Liaw
J Vasc Res. Author manuscript; available in PMC 2023 Jul 7.
Published in final edited form as: J Vasc Res. 2022; 59(5): 261–274. Published online 2022 Jul 7. doi: 10.1159/000525258
PMCID:
PMC9588530
AbstractArticlePDF–2.4M
5.
Notch2-mediated plasticity between marginal zone and follicular B cells
Markus Lechner, Thomas Engleitner, Tea Babushku, Marc Schmidt-Supprian, Roland Rad, Lothar J. Strobl, Ursula Zimber-Strobl
Nat Commun. 2021; 12: 1111. Published online 2021 Feb 17. doi: 10.1038/s41467-021-21359-1
PMCID:
PMC7889629
AbstractArticlePDF–5.4M
6.
Antisense oligonucleotides targeting Notch2 ameliorate the osteopenic phenotype in a mouse model of Hajdu-Cheney syndrome
Ernesto Canalis, Tamar R. Grossman, Michele Carrer, Lauren Schilling, Jungeun Yu
J Biol Chem. 2020 Mar 20; 295(12): 3952–3964. Published online 2020 Jan 28. doi: 10.1074/jbc.RA119.011440
PMCID:
PMC7086019
AbstractArticlePDF–4.4M
7.
The Hajdu Cheney mutation sensitizes mice to the osteolytic actions of tumor necrosis factor α
Jungeun Yu, Ernesto Canalis
J Biol Chem. 2019 Sep 27; 294(39): 14203–14214. Published online 2019 Aug 1. doi: 10.1074/jbc.RA119.009824
PMCID:
PMC6768656
AbstractArticlePDF–4.8M
8.
MICE HARBORING A HAJDU CHENEY SYNDROME MUTATION ARE SENSITIZED TO OSTEOARTHRITIS
S. Zanotti, J. Yu, D. Bridgewater, J.M. Wolf, E. Canalis
Bone. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: Bone. 2018 Sep; 114: 198–205. Published online 2018 Jun 22. doi: 10.1016/j.bone.2018.06.020
PMCID:
PMC6083868
AbstractArticlePDF–999K
9.
The Hajdu Cheney Mutation Is a Determinant of B-Cell Allocation of the Splenic Marginal Zone
Jungeun Yu, Stefano Zanotti, Bhavita Walia, Evan Jellison, Archana Sanjay, Ernesto Canalis
Am J Pathol. 2018 Jan; 188(1): 149–159. doi: 10.1016/j.ajpath.2017.09.010
PMCID:
PMC5745525
AbstractArticlePDF–2.7M
10.
PARATHYROID HORMONE INHIBITS NOTCH SIGNALING IN OSTEOBLASTS AND OSTEOCYTES
Stefano Zanotti, Ernesto Canalis
Bone. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Bone. 2017 Oct; 103: 159–167. Published online 2017 Jul 1. doi: 10.1016/j.bone.2017.06.027
PMCID:
PMC5568480
AbstractArticlePDF–765K
11.
An Antibody to Notch2 Reverses the Osteopenic Phenotype of Hajdu-Cheney Mutant Male Mice
Ernesto Canalis, Archana Sanjay, Jungeun Yu, Stefano Zanotti
Endocrinology. 2017 Apr 1; 158(4): 730–742. Published online 2017 Jan 31. doi: 10.1210/en.2016-1787
PMCID:
PMC5460801
AbstractArticle
12.
HAJDU CHENEY SYNDROME, A DISEASE ASSOCIATED WITH NOTCH2 MUTATIONS
Ernesto Canalis, Stefano Zanotti
Curr Osteoporos Rep. Author manuscript; available in PMC 2017 Aug 1.
Published in final edited form as: Curr Osteoporos Rep. 2016 Aug; 14(4): 126–131. doi: 10.1007/s11914-016-0311-6
PMCID:
PMC4927394
AbstractArticlePDF–108K
13.
Withaferin A inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown
Su-Hyeong Kim, Eun-Ryeong Hahm, Julie A. Arlotti, Suman K. Samanta, Michelle B. Moura, Stephen H. Thorne, Yongli Shuai, Carolyn J. Anderson, Alexander G. White, Anna Lokshin, Joomin Lee, Shivendra V. Singh
Breast Cancer Res Treat. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: Breast Cancer Res Treat. 2016 May; 157(1): 41–54. Published online 2016 Apr 21. doi: 10.1007/s10549-016-3795-y
PMCID:
PMC4867258
AbstractArticlePDF–1.9M
14.
Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice
Romina Fiorotto, Aileen Raizner, Carola M. Morell, Barbara Torsello, Roberto Scirpo, Luca Fabris, Carlo Spirli, Mario Strazzabosco
J Hepatol. Author manuscript; available in PMC 2013 Sep 19.
Published in final edited form as: J Hepatol. 2013 Jul; 59(1): 124–130. Published online 2013 Mar 7. doi: 10.1016/j.jhep.2013.02.025
PMCID:
PMC3777645
AbstractArticlePDF–1.8M
15.
Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to the prolonged injury
L. Albéri, Z. Chi, S.D. Kadam, J.D. Mulholland, V.L. Dawson, N. Gaiano, A.M. Comi
Stroke. Author manuscript; available in PMC 2011 Oct 1.
Published in final edited form as: Stroke. 2010 Oct; 41(10 Suppl): S64–S71. doi: 10.1161/STROKEAHA.110.595298
PMCID:
PMC3034189
AbstractArticlePDF–1.8M
16.
Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate
Mamiko Sakata-Yanagimoto, Etsuko Nakagami-Yamaguchi, Toshiki Saito, Keiki Kumano, Koji Yasutomo, Seishi Ogawa, Mineo Kurokawa, Shigeru Chiba
Proc Natl Acad Sci U S A. 2008 Jun 3; 105(22): 7839–7844. Published online 2008 May 22. doi: 10.1073/pnas.0801074105
PMCID:
PMC2409420
AbstractArticlePDF–1.2M
17.
Activated Notch2 Potentiates CD8 Lineage Maturation and Promotes the Selective Development of B1 B Cells
Colleen M. Witt, Vincent Hurez, C. Scott Swindle, Yoshio Hamada, Christopher A. Klug
Mol Cell Biol. 2003 Dec; 23(23): 8637–8650. doi: 10.1128/MCB.23.23.8637-8650.2003
PMCID:
PMC262652
AbstractArticlePDF–881K
18.
Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation
Brian T. Gaudette, Carly J. Roman, Trini A. Ochoa, Daniela Gómez Atria, Derek D. Jones, Christian W. Siebel, Ivan Maillard, David Allman
J Clin Invest. 2021 Oct 15; 131(20): e151975. Published online 2021 Oct 15. doi: 10.1172/JCI151975
PMCID:
PMC8516456
AbstractArticlePDF–9.7M
19.
Notch-regulated Dendritic Cells Restrain Inflammation-associated Colorectal Carcinogenesis
Lei Wang, Shuiliang Yu, Ernest R. Chan, Kai-Yuan Chen, Cui Liu, Danian Che, Amad Awadallah, Jay Myers, David Askew, Alex Y. Huang, Ivan Maillard, Dan Huang, Wei Xin, Lan Zhou
Cancer Immunol Res. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Cancer Immunol Res. 2021 Mar; 9(3): 348–361. Published online 2021 Jan 13. doi: 10.1158/2326-6066.CIR-20-0428
PMCID:
PMC7925430
AbstractArticlePDF–1.1M
20.
Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation
Francis M. Kobia, Kristina Preusse, Quanhui Dai, Nicholas Weaver, Matthew R. Hass, Praneet Chaturvedi, Sarah J. Stein, Warren S. Pear, Zhenyu Yuan, Rhett A. Kovall, Yi Kuang, Natanel Eafergen, David Sprinzak, Brian Gebelein, Eric W. Brunskill, Raphael Kopan
PLoS Biol. 2020 Oct; 18(10): e3000850. Published online 2020 Oct 5. doi: 10.1371/journal.pbio.3000850
PMCID:
PMC7561103
AbstractArticlePDF–5.1M

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