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Select item 54736331.

Metabolome and proteome changes with aging in Caenorhabditis elegans

Neil Copes, Clare Edwards, Dale Chaput, Mariam Saifee, Iosif Barjuca, Daniel Nelson, Alyssa Paraggio, Patrick Saad, David Lipps, Stanley M. Stevens, Jr., Patrick C. Bradshaw

Exp Gerontol. Author manuscript; available in PMC 2017 Jun 16.

Published in final edited form as: Exp Gerontol. 2015 Dec; 72: 67–84. Published online 2015 Sep 21. doi: 10.1016/j.exger.2015.09.013

PMCID:: PMC5473633

Abstract Article PDF–1.1M

Select item 99841912.

S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

Adwait A Godbole, Sneha Gopalan, Thien-Kim Nguyen, Alexander L Munden, Dominique S Lui, Matthew J Fanelli, Paula Vo, Caroline A Lewis, Jessica B Spinelli, Thomas G Fazzio, Amy K Walker

eLife. 2023; 12: e79511. Published online 2023 Feb 9. doi: 10.7554/eLife.79511

PMCID:: PMC9984191

Abstract Article PDF–2.6M

Select item 64244683.

Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion

Yasmine J. Liu, Georges E. Janssens, Rebecca L. McIntyre, Marte Molenaars, Rashmi Kamble, Arwen W. Gao, Aldo Jongejan, Michel van Weeghel, Alyson W. MacInnes, Riekelt H. Houtkooper

PLoS Genet. 2019 Mar; 15(3): e1007633. Published online 2019 Mar 7. doi: 10.1371/journal.pgen.1007633

PMCID:: PMC6424468

Abstract Article PDF–3.2M

Select item 40505484.

Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo

Nicole S. Hou, Aljona Gutschmidt, Daniel Y. Choi, Keouna Pather, Xun Shi, Jennifer L. Watts, Thorsten Hoppe, Stefan Taubert

Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22): E2271–E2280. Published online 2014 May 19. doi: 10.1073/pnas.1318262111

PMCID:: PMC4050548

Abstract Article PDF–1.7M

Select item 39682935.

S-Adenosyl methionine synthetase 1 limits fat storage in Caenorhabditis elegans

Madeleine Ehmke, Katharina Luthe, Ralf Schnabel, Frank Döring

Genes Nutr. 2014 Mar; 9(2): 386. Published online 2014 Feb 8. doi: 10.1007/s12263-014-0386-6

PMCID:: PMC3968293

Abstract Article PDF–2.0M

Select item 38984686.

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M. Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D.E. Greene, David Gems

Cell. 2013 Mar 28; 153(1): 228–239. doi: 10.1016/j.cell.2013.02.035

PMCID:: PMC3898468

Abstract Article PDF–922K

Select item 76575617.

S-adenosyl methionine synthetase SAMS-5 mediates dietary restriction-induced longevity in Caenorhabditis elegans

Chia-Chang Chen, Chiao Yin Lim, Pin-Jung Lee, Ao-Lin Hsu, Tsui-Ting Ching

PLoS One. 2020; 15(11): e0241455. Published online 2020 Nov 11. doi: 10.1371/journal.pone.0241455

PMCID:: PMC7657561

Abstract Article PDF–1.4M

Select item 41691908.

Interspecies Systems Biology Uncovers Metabolites Affecting C. elegans Gene Expression and Life History Traits

Emma Watson, Lesley T. MacNeil, Ashlyn D. Ritter, L. Safak Yilmaz, Adam P. Rosebrock, Amy A. Caudy, Albertha J. M. Walhout

Cell. Author manuscript; available in PMC 2014 Sep 19.

Published in final edited form as: Cell. 2014 Feb 13; 156(4): 759–770. doi: 10.1016/j.cell.2014.01.047

Correction in:: volume 156 on page 1336

PMCID:: PMC4169190

Abstract Article PDF–1.8M

Select item 49812739.

BLIMP-1/BLMP-1 and Metastasis-Associated Protein Regulate Stress Resistant Development in Caenorhabditis elegans

Moonjung Hyun, Jeongho Kim, Catherine Dumur, Frank C. Schroeder, Young-Jai You

Genetics. 2016 Aug; 203(4): 1721–1732. Published online 2016 Jun 21. doi: 10.1534/genetics.116.190793

PMCID:: PMC4981273

Abstract Article PDF–2.4M

Select item 497889510.

A Genetic Screen for Mutants with Supersized Lipid Droplets in Caenorhabditis elegans

Shiwei Li, Shibin Xu, Yanli Ma, Shuang Wu, Yu Feng, Qingpo Cui, Lifeng Chen, Shuang Zhou, Yuanyuan Kong, Xiaoyu Zhang, Jialei Yu, Mengdi Wu, Shaobing O. Zhang

G3 (Bethesda) 2016 Aug; 6(8): 2407–2419. Published online 2016 Jun 1. doi: 10.1534/g3.116.030866

PMCID:: PMC4978895

Abstract Article PDF–3.2M

Select item 270995911.

Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in C. elegans

Katherine A. Steinkraus, Erica D. Smith, Christina Davis, Daniel Carr, William R. Pendergrass, George L. Sutphin, Brian K. Kennedy, Matt Kaeberlein

Aging Cell. Author manuscript; available in PMC 2009 Jul 14.

Published in final edited form as: Aging Cell. 2008 Jun; 7(3): 394–404. Published online 2008 Mar 10. doi: 10.1111/j.1474-9726.2008.00385.x

PMCID:: PMC2709959

Abstract Article PDF–1.5M

Select item 388794412.

Cholesterol-Responsive Metabolic Proteins Are Required for Larval Development in Caenorhabditis elegans

Ichiro Kawasaki, Myung-Hwan Jeong, Yu-Joun Yun, Yun-Kyung Shin, Yhong-Hee Shim

Mol Cells. 2013 Nov 30; 36(5): 410–416. Published online 2013 Nov 8. doi: 10.1007/s10059-013-0170-2

PMCID:: PMC3887944

Abstract Article PDF–5.0M

Select item 499962713.

Biochemistry, function, and deficiency of vitamin B₁₂ in Caenorhabditis elegans

Tomohiro Bito, Fumio Watanabe

Exp Biol Med (Maywood) 2016 Sep; 241(15): 1663–1668. Published online 2016 Aug 2. doi: 10.1177/1535370216662713

PMCID:: PMC4999627

Abstract Article PDF–235K

Select item 377206614.

PAQR-2 Regulates Fatty Acid Desaturation during Cold Adaptation in C. elegans

Emma Svensk, Marcus Ståhlman, Carl-Henrik Andersson, Maja Johansson, Jan Borén, Marc Pilon

PLoS Genet. 2013 Sep; 9(9): e1003801. Published online 2013 Sep 12. doi: 10.1371/journal.pgen.1003801

PMCID:: PMC3772066

Abstract Article PDF–3.5M

Select item 966884315.

Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy

Rebecca A. Ellwood, Luke Slade, Jonathan Lewis, Roberta Torregrossa, Surabhi Sudevan, Mathew Piasecki, Matthew Whiteman, Timothy Etheridge, Nathaniel J. Szewczyk

Commun Biol. 2022; 5: 1255. Published online 2022 Nov 16. doi: 10.1038/s42003-022-04212-z

PMCID:: PMC9668843

Abstract Article PDF–3.4M

Select item 909032616.

Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle

Gokul G, Jogender Singh

eLife. 2022; 11: e76021. Published online 2022 Apr 19. doi: 10.7554/eLife.76021

PMCID:: PMC9090326

Abstract Article PDF–15M

Select item 989493517.

FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans

Hyo Sub Choi, Ajay Bhat, Marshall B. Howington, Megan L. Schaller, Rebecca L. Cox, Shijiao Huang, Safa Beydoun, Hillary A. Miller, Angela M. Tuckowski, Joy Mecano, Elizabeth S. Dean, Lindy Jensen, Daniel A. Beard, Charles R. Evans, Scott F. Leiser

Nat Commun. 2023; 14: 562. Published online 2023 Feb 2. doi: 10.1038/s41467-023-36181-0