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Select item 110314271.

Oncostatin M signaling drives cancer-associated skeletal muscle wasting

Aylin Domaniku-Waraich, Samet Agca, Batu Toledo, Melis Sucuoglu, Sevgi Döndü Özen, Sevval Nur Bilgic, Dilsad Hilal Arabaci, Aynur Erkin Kashgari, Serkan Kir

Cell Rep Med. 2024 Apr 16; 5(4): 101498. Published online 2024 Apr 4. doi: 10.1016/j.xcrm.2024.101498

PMCID:: PMC11031427

Abstract Article PDF–4.2M

Select item 109122912.

Oncostatin M: Dual Regulator of the Skeletal and Hematopoietic Systems

Natalie A. Sims, Jean-Pierre Lévesque

Curr Osteoporos Rep. 2024; 22(1): 80–95. Published online 2024 Jan 10. doi: 10.1007/s11914-023-00837-z

PMCID:: PMC10912291

Abstract Article PDF–2.1M

Select item 108612123.

Network‐based cytokine inference implicates Oncostatin M as a driver of an inflammation phenotype in knee osteoarthritis

Hirotaka Iijima, Fan Zhang, Fabrisia Ambrosio, Yusuke Matsui

Aging Cell. 2024 Feb; 23(2): e14043. Published online 2023 Dec 18. doi: 10.1111/acel.14043

PMCID:: PMC10861212

Abstract Article PDF–20M

Select item 107778764.

Oncostatin M Reduces Pathological Neovascularization in the Retina Through Müller Cell Activation

Julian Rapp, Alban Hospach, Paula Liang, Melanie Schwämmle, Lisa Renz, Hansjürgen Agostini, Günther Schlunck, Felicitas Bucher

Invest Ophthalmol Vis Sci. 2024 Jan; 65(1): 22. Published online 2024 Jan 8. doi: 10.1167/iovs.65.1.22

PMCID:: PMC10777876

Abstract Article PDF–5.8M

Select item 89532535.

Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback Regulator

Pedro P. C. de Souza, Petra Henning, Ulf H. Lerner

Int J Mol Sci. 2022 Mar; 23(6): 3287. Published online 2022 Mar 18. doi: 10.3390/ijms23063287

PMCID:: PMC8953253

Abstract Article PDF–2.0M

Select item 80909616.

Neutrophil-Derived Oncostatin M Triggers Diverse Signaling Pathways during Pneumonia

Katrina E. Traber, Ernest L. Dimbo, Anukul T. Shenoy, Elise M. Symer, Eri Allen, Joseph P. Mizgerd, Lee J. Quinton

Infect Immun. 2021 Apr; 89(4): e00655-20. Prepublished online 2021 Feb 1. Published online 2021 Mar 17. doi: 10.1128/IAI.00655-20

PMCID:: PMC8090961

Abstract Article PDF–1.5M

Select item 64067007.

Extracellular Matrix and Fibrocyte Accumulation in BALB/c Mouse Lung upon Transient Overexpression of Oncostatin M

Fernando M. Botelho, Rebecca Rodrigues, Jessica Guerette, Steven Wong, Dominik K. Fritz, Carl D. Richards

Cells. 2019 Feb; 8(2): 126. Published online 2019 Feb 5. doi: 10.3390/cells8020126

PMCID:: PMC6406700

Abstract Article PDF–2.0M

Select item 34255918.

Characterization of the Rat Oncostatin M Receptor Complex Which Resembles the Human, but Differs from the Murine Cytokine Receptor

Johannes Drechsler, Joachim Grötzinger, Heike M. Hermanns

PLoS One. 2012; 7(8): e43155. Published online 2012 Aug 22. doi: 10.1371/journal.pone.0043155

PMCID:: PMC3425591

Abstract Article PDF–2.4M

Select item 18508539.

Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand

Alfons S. K. de Hooge, Fons A. J. van de Loo, Miranda B. Bennink, Diana S. de Jong, Onno J. Arntz, Erik Lubberts, Carl D. Richards, Wim B. van den Berg

Am J Pathol. 2002 May; 160(5): 1733–1743. doi: 10.1016/s0002-9440(10)61120-0

PMCID:: PMC1850853

Abstract Article PDF–924K

Select item 897067810.

Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment

Angela M. Araujo, Andrea Abaurrea, Peio Azcoaga, Joanna I. López-Velazco, Sara Manzano, Javier Rodriguez, Ricardo Rezola, Leire Egia-Mendikute, Fátima Valdés-Mora, Juana M. Flores, Liam Jenkins, Laura Pulido, Iñaki Osorio-Querejeta, Patricia Fernández-Nogueira, Nicola Ferrari, Cristina Viera, Natalia Martín-Martín, Alexandar Tzankov, Serenella Eppenberger-Castori, Isabel Alvarez-Lopez, Ander Urruticoechea, Paloma Bragado, Nicholas Coleman, Asís Palazón, Arkaitz Carracedo, David Gallego-Ortega, Fernando Calvo, Clare M. Isacke, María M. Caffarel, Charles H. Lawrie

J Clin Invest. 2022 Apr 1; 132(7): e148667. Published online 2022 Apr 1. doi: 10.1172/JCI148667

Correction in:: J Clin Invest. 2022 Oct 3; 132(19): e165107.

PMCID:: PMC8970678

Abstract Article PDF–13M

Select item 874556211.

Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice

Holger Lörchner, Juan M. Adrian-Segarra, Christian Waechter, Roxanne Wagner, Maria Elisa Góes, Nathalie Brachmann, Krishnamoorthy Sreenivasan, Astrid Wietelmann, Stefan Günther, Nicolas Doll, Thomas Braun, Jochen Pöling

Int J Mol Sci. 2022 Jan; 23(1): 353. Published online 2021 Dec 29. doi: 10.3390/ijms23010353

PMCID:: PMC8745562

Abstract Article PDF–4.3M

Select item 858422112.

Murine Oncostatin M Has Opposing Effects on the Proliferation of OP9 Bone Marrow Stromal Cells and NIH/3T3 Fibroblasts Signaling through the OSMR

Lena Jakob, Tony Andreas Müller, Michael Rassner, Helen Kleinfelder, Pia Veratti, Jan Mitschke, Cornelius Miething, Robert A. J. Oostendorp, Dietmar Pfeifer, Miguel Waterhouse, Justus Duyster

Int J Mol Sci. 2021 Nov; 22(21): 11649. Published online 2021 Oct 28. doi: 10.3390/ijms222111649

PMCID:: PMC8584221

Abstract Article PDF–1.5M

Select item 671338613.

Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans

Danielle van Keulen, Marianne G. Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J. Pieterman, Ulf Hedin, Vilmundur Gudnason, Lori L. Jennings, Kim Holmstrøm, Boye Schnack Nielsen, Gerard Pasterkamp, Jan H. N. Lindeman, Alain J. van Gool, Maarten D. Sollewijn Gelpke, Hans M. G. Princen, Dennie Tempel

PLoS One. 2019; 14(8): e0221477. Published online 2019 Aug 28. doi: 10.1371/journal.pone.0221477

PMCID:: PMC6713386

Abstract Article PDF–4.2M

Select item 634119114.

Endothelial signaling by neutrophil-released oncostatin M enhances P-selectin–dependent inflammation and thrombosis

Hendra Setiadi, Tadayuki Yago, Zhenghui Liu, Rodger P. McEver

Blood Adv. 2019 Jan 22; 3(2): 168–183. Published online 2019 Jan 22. doi: 10.1182/bloodadvances.2018026294

PMCID:: PMC6341191

Abstract Article PDF–2.0M

Select item 631152015.

The AB loop of oncostatin M (OSM) determines species-specific signaling in humans and mice

Juan M. Adrian-Segarra, Krishnamoorthy Sreenivasan, Praveen Gajawada, Holger Lörchner, Thomas Braun, Jochen Pöling

J Biol Chem. 2018 Dec 28; 293(52): 20181–20199. Published online 2018 Oct 29. doi: 10.1074/jbc.RA118.004375

PMCID:: PMC6311520

Abstract Article PDF–6.9M

Select item 600116316.

OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara, Celeste Bolin, Jordan Koncinsky, Sujatha Kadaba, Hunter Covert, Caleb Sutherland, Laura Bond, Joseph Kronz, Joel R. Garbow, Cheryl L. Jorcyk

Breast Cancer Res. 2018; 20: 53. Published online 2018 Jun 14. doi: 10.1186/s13058-018-0971-5

PMCID:: PMC6001163

Abstract Article PDF–3.7M

Select item 529258617.

Oncostatin M Suppresses Activation of IL-17/Th17 via SOCS3 Regulation in CD4⁺ T Cells

Hye-Jin Son, Seung Hoon Lee, Seon-Yeong Lee, Eun-Kyung Kim, Eun-Ji Yang, Jae-Kyung Kim, Hyeon-Beom Seo, Sung-Hwan Park, Mi-La Cho

J Immunol. 2017 Feb 15; 198(4): 1484–1491. Published online 2017 Feb 6. doi: 10.4049/jimmunol.1502314

Correction in:: J Immunol. 2017 Jun 15; 198(12): 4879.

PMCID:: PMC5292586

Abstract Article PDF–1.2M

Select item 501611118.

Loss of Oncostatin M Signaling in Adipocytes Induces Insulin Resistance and Adipose Tissue Inflammation in Vivo

Carrie M. Elks, Peng Zhao, Ryan W. Grant, Hardy Hang, Jennifer L. Bailey, David H. Burk, Margaret A. McNulty, Randall L. Mynatt, Jacqueline M. Stephens

J Biol Chem. 2016 Aug 12; 291(33): 17066–17076. Published online 2016 Jun 20. doi: 10.1074/jbc.M116.739110

PMCID:: PMC5016111

Abstract Article PDF–2.0M

Select item 488513019.

Oncostatin M-induced cardiomyocyte dedifferentiation regulates the progression of diabetic cardiomyopathy through B-Raf/Mek/Erk signaling pathway

Xiaotian Zhang, Sai Ma, Ran Zhang, Shuang Li, Di Zhu, Dong Han, Xiujuan Li, Congye Li, Wei Yan, Dongdong Sun, Bin Xu, Yabin Wang, Feng Cao

Acta Biochim Biophys Sin (Shanghai) 2016 Mar; 48(3): 257–265. Published online 2016 Feb 1. doi: 10.1093/abbs/gmv137

PMCID:: PMC4885130

Abstract Article PDF–1.0M

Select item 447130420.

OSM Enhances Angiogenesis and Improves Cardiac Function after Myocardial Infarction

Xiaotian Zhang, Di Zhu, Liping Wei, Zhijing Zhao, Xin Qi, Zongjin Li, Dongdong Sun

Biomed Res Int. 2015; 2015: 317905. Published online 2015 Jun 4. doi: 10.1155/2015/317905

PMCID:: PMC4471304

Abstract Article PDF–3.4M

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