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Select item 111159221.

CK2 phosphorylation of Pdx-1 regulates its transcription factor activity

Rui Meng, Faizeh Al-Quobaili, Isabelle Müller, Claudia Götz, Gerald Thiel, Mathias Montenarh

Cell Mol Life Sci. 2010 Jul; 67(14): 2481–2489. Published online 2010 Mar 26. doi: 10.1007/s00018-010-0348-0

PMCID:: PMC11115922

Abstract Article PDF–517K

Select item 85644122.

OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1

Ramkumar Mohan, Seokwon Jo, Amber Lockridge, Deborah A. Ferrington, Kevin Murray, Arthur Eschenlauer, Ernesto Bernal-Mizrachi, Yoshio Fujitani, Emilyn U. Alejandro

Diabetes. 2021 Nov; 70(11): 2608–2625. Published online 2021 Aug 30. doi: 10.2337/db21-0468

PMCID:: PMC8564412

Abstract Article PDF–3.7M

Select item 77163883.

Acarbose ameliorates spontaneous type-2 diabetes in db/db mice by inhibiting PDX-1 methylation

Diyi Zhou, Lijun Chen, Xin Mou

Mol Med Rep. 2021 Jan; 23(1): 72. Published online 2020 Nov 20. doi: 10.3892/mmr.2020.11710

PMCID:: PMC7716388

Abstract Article PDF–869K

Select item 69518024.

Neonatal diabetes mellitus with pancreatic agenesis in an infant with homozygous IPF-1 Pro63fsX60 mutation

Inas H. Thomas, Natinder K. Saini, Amita Adhikari, Joyce M. Lee, Josephine Z. Kasa-vubu, Delia M. Vazquez, Ram K. Menon, Ming Chen, Stefan S. Fajans

Pediatr Diabetes. Author manuscript; available in PMC 2020 Jan 9.

Published in final edited form as: Pediatr Diabetes. 2009 Nov; 10(7): 492–496. Published online 2009 Jun 3. doi: 10.1111/j.1399-5448.2009.00526.x

PMCID:: PMC6951802

Abstract Article PDF–726K

Select item 61977475.

A PDX1-ATF transcriptional complex governs β cell survival during stress

Christine A. Juliana, Juxiang Yang, Corey E. Cannon, Austin L. Good, Matthew W. Haemmerle, Doris A. Stoffers

Mol Metab. 2018 Nov; 17: 39–48. Published online 2018 Aug 1. doi: 10.1016/j.molmet.2018.07.007

PMCID:: PMC6197747

Abstract Article PDF–1.5M

Select item 49426076.

Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model

Chuang Guo, Shuai Zhang, Jia-Yi Li, Chen Ding, Zhao-Hui Yang, Rui Chai, Xu Wang, Zhan-You Wang

Sci Rep. 2016; 6: 29396. Published online 2016 Jul 12. doi: 10.1038/srep29396

PMCID:: PMC4942607

Abstract Article PDF–2.6M

Select item 39509647.

Pdx1 maintains β-cell identity and function by repressing an α-cell program

Tao Gao, Brian McKenna, Changhong Li, Maximilian Reichert, James Nguyen, Tarjinder Singh, Chenghua Yang, Archana Pannikar, Nicolai Doliba, Tingting Zhang, Doris A. Stoffers, Helena Edlund, Franz Matschinsky, Roland Stein, Ben Z. Stanger

Cell Metab. Author manuscript; available in PMC 2015 Feb 4.

Published in final edited form as: Cell Metab. 2014 Feb 4; 19(2): 259–271. doi: 10.1016/j.cmet.2013.12.002

PMCID:: PMC3950964

Abstract Article PDF–3.3M

Select item 34129128.

Intestinal Pdx1 mediates nutrient metabolism gene networks and maternal expression is essential for perinatal growth in mice

Chin Chen, Tripp Leavitt, Eric Sibley

Biochem Biophys Res Commun. Author manuscript; available in PMC 2013 Aug 3.

Published in final edited form as: Biochem Biophys Res Commun. 2012 Aug 3; 424(3): 549–553. Published online 2012 Jul 6. doi: 10.1016/j.bbrc.2012.06.153

PMCID:: PMC3412912

Abstract Article PDF–823K

Select item 32873939.

Expression profiling identifies novel gene targets and functions for Pdx1 in the duodenum of mature mice

Chin Chen, Eric Sibley

Am J Physiol Gastrointest Liver Physiol. 2012 Feb; 302(4): G407–G419. Published online 2011 Dec 1. doi: 10.1152/ajpgi.00314.2011

PMCID:: PMC3287393

Abstract Article

Select item 285009410.

Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells

Chin Chen, Rixun Fang, Corrine Davis, Charalambos Maravelias, Eric Sibley

Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6): G1126–G1137. Published online 2009 Oct 1. doi: 10.1152/ajpgi.90586.2008

PMCID:: PMC2850094

Abstract Article

Select item 277711211.

Pancreatic Ductal Morphogenesis and the Pdx1 Homeodomain Transcription Factor

Melanie P. Wescott, Meritxell Rovira, Maximilian Reichert, Johannes von Burstin, Anna Means, Steven D. Leach, Anil K. Rustgi

Mol Biol Cell. 2009 Nov 15; 20(22): 4838–4844. doi: 10.1091/mbc.E09-03-0203

PMCID:: PMC2777112

Abstract Article PDF–1.8M

Select item 277643312.

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

Mira M. Sachdeva, Kathryn C. Claiborn, Cynthia Khoo, Juxiang Yang, David N. Groff, Raghavendra G. Mirmira, Doris A. Stoffers

Proc Natl Acad Sci U S A. 2009 Nov 10; 106(45): 19090–19095. Published online 2009 Oct 23. doi: 10.1073/pnas.0904849106

PMCID:: PMC2776433

Abstract Article PDF–1.9M

Select item 174826713.

Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome

James D. Johnson, Ernesto Bernal-Mizrachi, Emilyn U. Alejandro, Zhiqiang Han, Tatyana B. Kalynyak, Hong Li, Jennifer L. Beith, Julia Gross, Garth L. Warnock, R. Reid Townsend, M. Alan Permutt, Kenneth S. Polonsky

Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51): 19575–19580. Published online 2006 Dec 8. doi: 10.1073/pnas.0604208103