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Select item 90694091.

Targeting PFKL with penfluridol inhibits glycolysis and suppresses esophageal cancer tumorigenesis in an AMPK/FOXO3a/BIM-dependent manner

Cancan Zheng, Xiaomei Yu, Yiyao Liang, Yidong Zhu, Yan He, Long Liao, Dingkang Wang, Yanming Yang, Xingfeng Yin, Ang Li, Qingyu He, Bin Li

Acta Pharm Sin B. 2022 Mar; 12(3): 1271–1287. Published online 2021 Sep 11. doi: 10.1016/j.apsb.2021.09.007

PMCID:: PMC9069409

Abstract Article PDF–5.1M

Select item 11382872.

Overexpression of liver-type phosphofructokinase (PFKL) in transgenic-PFKL mice: implication for gene dosage in trisomy 21.

A Elson, D Levanon, Y Weiss, Y Groner

Biochem J. 1994 Apr 15; 299(Pt 2): 409–415. doi: 10.1042/bj2990409

PMCID:: PMC1138287

Summary Page Browse PDF–1.7M

Select item 99443233.

The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling during cardiac hypertrophy in male mice

Cao Wang, Shupei Qiao, Yufang Zhao, Hui Tian, Wei Yan, Xiaolu Hou, Ruiqi Wang, Bosong Zhang, Chaofan Yang, Fuxing Zhu, Yanwen Jiao, Jiaming Jin, Yue Chen, Weiming Tian

Nat Commun. 2023; 14: 959. Published online 2023 Feb 21. doi: 10.1038/s41467-023-36712-9

PMCID:: PMC9944323

Abstract Article PDF–3.3M

Select item 3107124.

The Mouse Aire Gene: Comparative Genomic Sequencing, Gene Organization, and Expression

Karin Blechschmidt, Michal Schweiger, Karin Wertz, Richard Poulson, Hoang-My Christensen, Andre Rosenthal, Hans Lehrach, Marie-Laure Yaspo

Genome Res. 1999 Feb; 9(2): 158–166.

PMCID:: PMC310712

Abstract Article PDF–3.7M

Select item 62246015.

TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation

Le Li, Lijia Li, Wei Li, Taiqi Chen, Bin Zou, Lina Zhao, Huili Wang, Xueying Wang, Lina Xu, Xiaohui Liu, Dong Wang, Bo Li, Tak W. Mak, Wenjing Du, Xiaolu Yang, Peng Jiang

Nat Commun. 2018; 9: 4683. Published online 2018 Nov 8. doi: 10.1038/s41467-018-07127-8

PMCID:: PMC6224601

Abstract Article PDF–1.8M

Select item 14606926.

A new mouse insertional mutation that causes sensorineural deafness and vestibular defects.

K N Alagramam, H Y Kwon, N L Cacheiro, L Stubbs, C G Wright, L C Erway, R P Woychik

Genetics. 1999 Aug; 152(4): 1691–1699. doi: 10.1093/genetics/152.4.1691

PMCID:: PMC1460692

Summary PDF–332K

Select item 110940737.

Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance

Jessie E Buth, Catherine E Dyevich, Alexandra Rubin, Chengbing Wang, Lei Gao, Tessa Marks, Michael RM Harrison, Jennifer H Kong, M Elizabeth Ross, Bennett G Novitch, Caroline Alayne Pearson

EMBO Rep. 2024 May; 25(5): 2202–2219. Published online 2024 Apr 10. doi: 10.1038/s44319-024-00131-8

PMCID:: PMC11094073

Abstract Article PDF–13M

Select item 52786288.

Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching

Hidenobu Miyazawa, Yoshifumi Yamaguchi, Yuki Sugiura, Kurara Honda, Koki Kondo, Fumio Matsuda, Takehiro Yamamoto, Makoto Suematsu, Masayuki Miura

Development. 2017 Jan 1; 144(1): 63–73. doi: 10.1242/dev.138545

PMCID:: PMC5278628

Abstract Article

Select item 30641739.

Cardiomyocyte-specific Prolyl-4-hydroxylase Domain 2 Knock Out Protects from Acute Myocardial Ischemic Injury

Marion Hölscher, Monique Silter, Sabine Krull, Melanie von Ahlen, Amke Hesse, Peter Schwartz, Ben Wielockx, Georg Breier, Dörthe M. Katschinski, Anke Zieseniss

J Biol Chem. 2011 Apr 1; 286(13): 11185–11194. Published online 2011 Jan 26. doi: 10.1074/jbc.M110.186809

PMCID:: PMC3064173

Abstract Article PDF–2.4M

Select item 420761810.

Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse

Tia DiTommaso, Lynelle K. Jones, Denny L. Cottle, The WTSI Mouse Genetics Program, Anna-Karin Gerdin, Valerie E. Vancollie, Fiona M. Watt, Ramiro Ramirez-Solis, Allan Bradley, Karen P. Steel, John P. Sundberg, Jacqueline K. White, Ian M. Smyth

PLoS Genet. 2014 Oct; 10(10): e1004705. Published online 2014 Oct 23. doi: 10.1371/journal.pgen.1004705

PMCID:: PMC4207618

Abstract Article PDF–1.8M

Select item 285952711.

Hearts of Hypoxia-inducible Factor Prolyl 4-Hydroxylase-2 Hypomorphic Mice Show Protection against Acute Ischemia-Reperfusion Injury

Jaana Hyvärinen, Ilmo E. Hassinen, Raija Sormunen, Joni M. Mäki, Kari I. Kivirikko, Peppi Koivunen, Johanna Myllyharju

J Biol Chem. 2010 Apr 30; 285(18): 13646–13657. Published online 2010 Feb 25. doi: 10.1074/jbc.M109.084855

PMCID:: PMC2859527

Abstract Article PDF–4.3M

Select item 463178712.

A gene expression resource generated by genome-wide lacZ profiling in the mouse

Elizabeth Tuck, Jeanne Estabel, Anika Oellrich, Anna Karin Maguire, Hibret A. Adissu, Luke Souter, Emma Siragher, Charlotte Lillistone, Angela L. Green, Hannah Wardle-Jones, Damian M. Carragher, Natasha A. Karp, Damian Smedley, Niels C. Adams, Sanger Institute Mouse Genetics Project, James N. Bussell, David J. Adams, Ramiro Ramírez-Solis, Karen P. Steel, Antonella Galli, Jacqueline K. White

Dis Model Mech. 2015 Nov 1; 8(11): 1467–1478. doi: 10.1242/dmm.021238

PMCID:: PMC4631787

Abstract Article

Select item 399654213.

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen

Kifayathullah Liakath-Ali, Valerie E. Vancollie, Emma Heath, Damian P. Smedley, Jeanne Estabel, David Sunter, Tia DiTommaso, Jacqueline K. White, Ramiro Ramirez-Solis, Ian Smyth, Karen P. Steel, Fiona M. Watt

Nat Commun. 2014 Apr 11; 5: 3540. Published online 2014 Apr 11. doi: 10.1038/ncomms4540

PMCID:: PMC3996542

Abstract Article PDF–4.0M

Select item 197613414.

An analysis of expression patterns of genes encoding proteins with catalytic activities

Murat Cankaya, Ana Martinez Hernandez, Mehmet Ciftci, Sukru Beydemir, Hasan Ozdemir, Harun Budak, Ilhami Gulcin, Veysel Comakli, Tufan Emircupani, Deniz Ekinci, Muslum Kuzu, Qiuhong Jiang, Gregor Eichele, Omer Irfan Kufrevioglu

BMC Genomics. 2007; 8: 232. Published online 2007 Jul 12. doi: 10.1186/1471-2164-8-232

PMCID:: PMC1976134

Abstract Article PDF–1.5M

Select item 31100415.

Perfect Conserved Linkage Across the Entire Mouse Chromosome 10 Region Homologous to Human Chromosome 21

Tim Wiltshire, Mathew Pletcher, Susan E. Cole, Melissa Villanueva, Bruce Birren, Jessica Lehoczky, Ken Dewar, Roger H. Reeves

Genome Res. 1999 Dec; 9(12): 1214–1222. doi: 10.1101/gr.9.12.1214

PMCID:: PMC311004

Abstract Article PDF–726K

Select item 494642716.

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series

Caitlyn E. Bowman, Liang Zhao, Thomas Hartung, Michael J. Wolfgang

Mol Cell Biol. 2016 Aug 1; 36(15): 2089–2104. Prepublished online 2016 May 23. Published online 2016 Jul 14. doi: 10.1128/MCB.00166-16

PMCID:: PMC4946427

Abstract Article PDF–3.4M

Select item 504520017.

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa

PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355

PMCID:: PMC5045200

Abstract Article PDF–2.9M

Select item 533761818.

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla

Dev Cell. 2017 Feb 27; 40(4): 331–341.e4. doi: 10.1016/j.devcel.2017.01.015

PMCID:: PMC5337618

Abstract Article

Select item 606970519.

RNA binding proteins co-localize with small tau inclusions in tauopathy

Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin

Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5

PMCID:: PMC6069705

Abstract Article PDF–5.5M

Select item 626277720.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214