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Select item 96594921.

Visuosocial Preference Memory, but Not Avoidance Memory, Requires PLCγ1 in the CA2 Hippocampus

Sunpil Kim, Jeongyeon Kim, Yongmin Mason Park, Pann-Ghill Suh, C. Justin Lee

Exp Neurobiol. 2022 Oct 31; 31(5): 332–342. Published online 2022 Oct 31. doi: 10.5607/en22033

PMCID:: PMC9659492

Abstract Article PDF–1.2M

Select item 55590872.

Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development

Guoping Fu, Mei Yu, Yuhong Chen, Yongwei Zheng, Wen Zhu, Debra K. Newman, Demin Wang, Renren Wen

Eur J Immunol. Author manuscript; available in PMC 2017 Aug 16.

Published in final edited form as: Eur J Immunol. 2017 Jan; 47(1): 74–83. Published online 2016 Nov 7. doi: 10.1002/eji.201646522

PMCID:: PMC5559087

Abstract Article PDF–1.6M

Select item 35673663.

Important role of PLC-γ1 in hypoxic increase in intracellular calcium in pulmonary arterial smooth muscle cells

Vishal R. Yadav, Tengyao Song, Leroy Joseph, Lin Mei, Yun-Min Zheng, Yong-Xiao Wang

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 1; 304(3): L143–L151. Published online 2012 Nov 30. doi: 10.1152/ajplung.00310.2012

PMCID:: PMC3567366

Abstract Article

Select item 26965864.

PLC-γ1 Regulates Fibronectin Assembly and Cell Aggregation

Cornelia E. Crooke, Ambra Pozzi, Graham F. Carpenter

Exp Cell Res. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: Exp Cell Res. 2009 Aug 1; 315(13): 2207–2214. Published online 2009 Apr 18. doi: 10.1016/j.yexcr.2009.04.008

PMCID:: PMC2696586

Abstract Article PDF–1.7M

Select item 13565905.

Targeting of Protein Kinase C-ε during Fcγ Receptor-dependent Phagocytosis Requires the εC1B Domain and Phospholipase C-γ1

Keylon L. Cheeseman, Takehiko Ueyama, Tanya M. Michaud, Kaori Kashiwagi, Demin Wang, Lindsay A. Flax, Yasuhito Shirai, Daniel J. Loegering, Naoaki Saito, Michelle R. Lennartz

Mol Biol Cell. 2006 Feb; 17(2): 799–813. doi: 10.1091/mbc.E04-12-1100

PMCID:: PMC1356590

Abstract Article PDF–825K

Select item 12224916.

Phospholipase C-gamma1 is required for cell survival in oxidative stress by protein kinase C.

Xiao-Chun Bai, Fan Deng, An-Ling Liu, Zhi-Peng Zou, Yu Wang, Zhi-Yong Ke, Qun-Sheng Ji, Shen-Qiu Luo

Biochem J. 2002 Apr 15; 363(Pt 2): 395–401. doi: 10.1042/0264-6021:3630395

PMCID:: PMC1222491

Summary PDF–236K

Select item 203117.

Essential role of the tyrosine kinase substrate phospholipase C-γ1 in mammalian growth and development

Qun-sheng Ji, Glenn E. Winnier, Kevin D. Niswender, Debra Horstman, Ron Wisdom, Mark A. Magnuson, Graham Carpenter

Proc Natl Acad Sci U S A. 1997 Apr 1; 94(7): 2999–3003. doi: 10.1073/pnas.94.7.2999

PMCID:: PMC20311

Abstract Article PDF–576K

Select item 95927688.

Loss of phospholipase Cγ1 suppresses hepatocellular carcinogenesis through blockade of STAT3‐mediated cancer development

Eun‐Bi Seo, Hyun‐Jun Jang, Sun‐Ho Kwon, Yong‐Jin Kwon, Seul‐Ki Kim, Song‐Hee Lee, Ae Jin Jeong, Hyun Mu Shin, Yong‐Nyun Kim, Stephanie Ma, Haeryoung Kim, Yun‐Han Lee, Pann‐Ghill Suh, Sang‐Kyu Ye

Hepatol Commun. 2022 Nov; 6(11): 3234–3246. Published online 2022 Sep 25. doi: 10.1002/hep4.2077

PMCID:: PMC9592768

Abstract Article PDF–48M

Select item 88546759.

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal

Tina M. Schnoeder, Adrian Schwarzer, Ashok Kumar Jayavelu, Chen-Jen Hsu, Joanna Kirkpatrick, Konstanze Döhner, Florian Perner, Theresa Eifert, Nicolas Huber, Patricia Arreba-Tutusaus, Anna Dolnik, Salam A. Assi, Monica Nafria, Lu Jiang, Yu-Ting Dai, Zhu Chen, Sai-Juan Chen, Sophie G. Kellaway, Anetta Ptasinska, Elizabeth S. Ng, Edouard G. Stanley, Andrew G. Elefanty, Marcus Buschbeck, Holger Bierhoff, Steffen Brodt, Georg Matziolis, Klaus-Dieter Fischer, Andreas Hochhaus, Chun-Wei Chen, Olaf Heidenreich, Matthias Mann, Steven W. Lane, Lars Bullinger, Alessandro Ori, Björn von Eyss, Constanze Bonifer, Florian H. Heidel

Blood. 2022 Feb 17; 139(7): 1080–1097. doi: 10.1182/blood.2021012778

PMCID:: PMC8854675

Abstract Article

Select item 877624710.

Erythroid Differentiation Regulator 1 Strengthens TCR Signaling by Enhancing PLCγ1 Signal Transduction Pathway

Myun Soo Kim, Dongmin Park, Sora Lee, Sunyoung Park, Kyung Eun Kim, Tae Sung Kim, Hyun Jeong Park, Daeho Cho

Int J Mol Sci. 2022 Jan; 23(2): 844. Published online 2022 Jan 13. doi: 10.3390/ijms23020844

PMCID:: PMC8776247

Abstract Article PDF–1.9M

Select item 782634711.

Prediction of Alzheimer’s disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening

Sung-Hyun Kim, Sumin Yang, Key-Hwan Lim, Euiseng Ko, Hyun-Jun Jang, Mingon Kang, Pann-Ghill Suh, Jae-Yeol Joo

Proc Natl Acad Sci U S A. 2021 Jan 19; 118(3): e2011250118. Published online 2021 Jan 4. doi: 10.1073/pnas.2011250118

Correction in:: Proc Natl Acad Sci U S A. 2021 Mar 2; 118(9): e2101727118.

PMCID:: PMC7826347

Abstract Article PDF–2.3M

Select item 767933712.

Modulation of calcium signaling depends on the oligosaccharide of GM1 in Neuro2a mouse neuroblastoma cells

Giulia Lunghi, Maria Fazzari, Erika Di Biase, Laura Mauri, Sandro Sonnino, Elena Chiricozzi

Glycoconj J. 2020; 37(6): 713–727. Published online 2020 Nov 17. doi: 10.1007/s10719-020-09963-7

PMCID:: PMC7679337

Abstract Article PDF–2.8M

Select item 764197013.

Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer

Wenqiang Song, Laura C. Kim, Wei Han, Yuan Hou, Deanna Edwards, Shan Wang, Timothy S. Blackwell, Feixiong Cheng, Dana M. Brantley-Sieders, Jin Chen

Mol Cancer Res. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Mol Cancer Res. 2020 Nov; 18(11): 1735–1743. Published online 2020 Aug 4. doi: 10.1158/1541-7786.MCR-20-0075

PMCID:: PMC7641970

Abstract Article PDF–2.1M

Select item 688288414.

Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice

Hye Yun Kim, Yong Ryoul Yang, Hongik Hwang, Ha-Eun Lee, Hyun-Jun Jang, Jeongyeon Kim, Esther Yang, Hyun Kim, Hyewhon Rhim, Pann-Ghill Suh, Jae-Ick Kim

Sci Rep. 2019; 9: 17761. Published online 2019 Nov 28. doi: 10.1038/s41598-019-54477-4

PMCID:: PMC6882884

Abstract Article PDF–1.8M

Select item 667384515.

Hippocampal Long-Term Potentiation Is Supported by Presynaptic and Postsynaptic Tyrosine Receptor Kinase B-Mediated Phospholipase Cγ Signaling

Annette Gärtner, Dorit G. Polnau, Volker Staiger, Carla Sciarretta, Liliana Minichiello, Hans Thoenen, Tobias Bonhoeffer, Martin Korte

J Neurosci. 2006 Mar 29; 26(13): 3496–3504. doi: 10.1523/JNEUROSCI.3792-05.2006

PMCID:: PMC6673845

Abstract Article PDF–2.7M

Select item 436882216.

Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1

Yongwei Zheng, Tamara Adams, Huiying Zhi, Mei Yu, Renren Wen, Peter J. Newman, Demin Wang, Debra K. Newman

PLoS One. 2015; 10(3): e0119739. Published online 2015 Mar 20. doi: 10.1371/journal.pone.0119739

PMCID:: PMC4368822

Abstract Article PDF–1.4M

Select item 435562917.

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

Sudha Kumari, David Depoil, Roberta Martinelli, Edward Judokusumo, Guillaume Carmona, Frank B Gertler, Lance C Kam, Christopher V Carman, Janis K Burkhardt, Darrell J Irvine, Michael L Dustin

eLife. 2015; 4: e04953. Published online 2015 Mar 11. doi: 10.7554/eLife.04953

PMCID:: PMC4355629

Abstract Article PDF–5.8M

Select item 364636318.

The role of the LAT-PLC-γ1 interaction in T regulatory cell function

Mariana I Chuck, Minghua Zhu, Shudan Shen, Weiguo Zhang

J Immunol. Author manuscript; available in PMC 2013 May 7.

Published in final edited form as: J Immunol. 2010 Mar 1; 184(5): 2476–2486. Published online 2010 Feb 3. doi: 10.4049/jimmunol.0902876

PMCID:: PMC3646363

Abstract Article PDF–2.7M

Select item 296453419.

PLCγ-activated signalling is essential for TrkB mediated sensory neuron structural plasticity

Carla Sciarretta, Bernd Fritzsch, Kirk Beisel, Sonia M Rocha-Sanchez, Annalisa Buniello, Jacqueline M Horn, Liliana Minichiello

BMC Dev Biol. 2010; 10: 103. Published online 2010 Oct 8. doi: 10.1186/1471-213X-10-103

PMCID:: PMC2964534

Abstract Article PDF–11M

Select item 286371620.

Phospholipase Cγ Activation Drives Increased Production of Autotaxin in Endothelial Cells and Lysophosphatidic Acid-Dependent Regression

Eunok Im, Ruta Motiejunaite, Jorge Aranda, Eun Young Park, Lorenzo Federico, Tae-im Kim, Timothy Clair, Mary L. Stracke, Susan Smyth, Andrius Kazlauskas

Mol Cell Biol. 2010 May; 30(10): 2401–2410. Published online 2010 Mar 15. doi: 10.1128/MCB.01275-09

PMCID:: PMC2863716

Abstract Article PDF–1.3M

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