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Select item 87841281.

Reevaluation of the role of LIP-1 as an ERK/MPK-1 dual specificity phosphatase in the C. elegans germline

Debabrata Das, Jacob Seemann, David Greenstein, Tim Schedl, Swathi Arur

Proc Natl Acad Sci U S A. 2022 Jan 18; 119(3): e2113649119. Published online 2022 Jan 12. doi: 10.1073/pnas.2113649119

PMCID:: PMC8784128

Abstract Article PDF–2.5M

Select item 82087892.

Oocyte aging is controlled by mitogen‐activated protein kinase signaling

Hanna Achache, Roni Falk, Noam Lerner, Tsevi Beatus, Yonatan B. Tzur

Aging Cell. 2021 Jun; 20(6): e13386. Published online 2021 Jun 1. doi: 10.1111/acel.13386

PMCID:: PMC8208789

Abstract Article PDF–1.9M

Select item 64995233.

Progression of Meiosis Is Coordinated by the Level and Location of MAPK Activation Via OGR-2 in Caenorhabditis elegans

Hanna Achache, Lévana Laurent, Yaël Hecker-Mimoun, Hasan Ishtayeh, Yisrael Rappaport, Eitan Kroizer, Monica P. Colaiácovo, Yonatan B. Tzur

Genetics. 2019 May; 212(1): 213–229. Published online 2019 Mar 12. doi: 10.1534/genetics.119.302080

PMCID:: PMC6499523

Abstract Article PDF–2.3M

Select item 18687744.

Predictive Modeling of Signaling Crosstalk during C. elegans Vulval Development

Jasmin Fisher, Nir Piterman, Alex Hajnal, Thomas A Henzinger

PLoS Comput Biol. 2007 May; 3(5): e92. Published online 2007 May 18. doi: 10.1371/journal.pcbi.0030092

PMCID:: PMC1868774

Abstract Article PDF–973K

Select item 99135195.

Genetic and Chemical Controls of Sperm Fate and Spermatocyte Dedifferentiation via PUF-8 and MPK-1 in Caenorhabditis elegans

Youngyong Park, Matthew Gaddy, Moonjung Hyun, Mariah E. Jones, Hafiz M. Aslam, Myon Hee Lee

Cells. 2023 Feb; 12(3): 434. Published online 2023 Jan 28. doi: 10.3390/cells12030434

PMCID:: PMC9913519

Abstract Article PDF–2.7M

Select item 41966136.

Competence for Chemical Reprogramming of Sexual Fate Correlates with an Intersexual Molecular Signature in Caenorhabditis elegans

Elena P. Sorokin, Audrey P. Gasch, Judith Kimble

Genetics. 2014 Oct; 198(2): 561–575. Published online 2014 Aug 21. doi: 10.1534/genetics.114.169409

PMCID:: PMC4196613

Abstract Article PDF–2.1M

Select item 55816797.

MPK-1/ERK Regulatory Network Controls the Number of Sperm by Regulating Timing of Sperm-Oocyte Switch in C. elegans Germline

Dong Suk Yoon, Mohammad A. Alfhili, Kyle Friend, Myon-Hee Lee

Biochem Biophys Res Commun. Author manuscript; available in PMC 2018 Sep 30.

Published in final edited form as: Biochem Biophys Res Commun. 2017 Sep 30; 491(4): 1077–1082. Published online 2017 Aug 3. doi: 10.1016/j.bbrc.2017.08.014

PMCID:: PMC5581679

Abstract Article PDF–1.3M

Select item 31619418.

Regulation of Caenorhabditis elegans p53/CEP-1–Dependent Germ Cell Apoptosis by Ras/MAPK Signaling

Rachael Rutkowski, Robin Dickinson, Graeme Stewart, Ashley Craig, Marianne Schimpl, Stephen M. Keyse, Anton Gartner

PLoS Genet. 2011 Aug; 7(8): e1002238. Published online 2011 Aug 25. doi: 10.1371/journal.pgen.1002238

PMCID:: PMC3161941

Abstract Article PDF–3.1M

Select item 28086319.

Chemical reprogramming of Caenorhabditis elegans germ cell fate

Clinton T. Morgan, Myon-Hee Lee, Judith Kimble

Nat Chem Biol. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: Nat Chem Biol. 2010 Feb; 6(2): 102–104. Published online 2009 Dec 20. doi: 10.1038/nchembio.282

PMCID:: PMC2808631

Abstract Article PDF–305K

Select item 232332510.

Conserved Regulation of MAP Kinase Expression by PUF RNA-Binding Proteins

Myon-Hee Lee, Brad Hook, Guangjin Pan, Aaron M Kershner, Christopher Merritt, Geraldine Seydoux, James A Thomson, Marvin Wickens, Judith Kimble

PLoS Genet. 2007 Dec; 3(12): e233. Published online 2007 Dec 28. doi: 10.1371/journal.pgen.0030233

PMCID:: PMC2323325

Abstract Article PDF–850K

Select item 12616811.

The C.elegans MAPK phosphatase LIP-1 is required for the G₂/M meiotic arrest of developing oocytes

Alex Hajnal, Thomas Berset

EMBO J. 2002 Aug 15; 21(16): 4317–4326. doi: 10.1093/emboj/cdf430

PMCID:: PMC126168

Abstract Article PDF–285K

Select item 294327712.

The ERK-MAPK Pathway Regulates Longevity through SKN-1 and Insulin-like Signaling in Caenorhabditis elegans

Tetsuya Okuyama, Hideki Inoue, Sadatsugu Ookuma, Takayuki Satoh, Kei Kano, Sakiko Honjoh, Naoki Hisamoto, Kunihiro Matsumoto, Eisuke Nishida

J Biol Chem. 2010 Sep 24; 285(39): 30274–30281. Published online 2010 Jul 12. doi: 10.1074/jbc.M110.146274

PMCID:: PMC2943277

Abstract Article PDF–1.5M

Select item 244197813.

C. elegans La-related protein, LARP-1, localizes to germline P bodies and attenuates Ras-MAPK signaling during oogenesis

Keith Nykamp, Myon-Hee Lee, Judith Kimble

RNA. 2008 Jul; 14(7): 1378–1389. doi: 10.1261/rna.1066008

PMCID:: PMC2441978

Abstract Article PDF–785K

Select item 337833214.

Protein kinase VRK-1 regulates cell invasion and EGL-17/FGF signaling in Caenorhabditis elegans

Elke P.F. Klerkx, Pilar Alarcón, Katherine Waters, Valerie Reinke, Paul W. Sternberg, Peter Askjaer

Dev Biol. Author manuscript; available in PMC 2012 Jun 19.

Published in final edited form as: Dev Biol. 2009 Nov 1; 335(1): 12–21. Published online 2009 Aug 11. doi: 10.1016/j.ydbio.2009.08.007

PMCID:: PMC3378332

Abstract Article PDF–3.0M

Select item 302898415.

Ras Effector Switching Promotes Divergent Cell Fates in C. elegans Vulval Patterning

Tanya P. Zand, David J. Reiner, Channing J. Der

Dev Cell. Author manuscript; available in PMC 2012 Jan 18.

Published in final edited form as: Dev Cell. 2011 Jan 18; 20(1): 84–96. doi: 10.1016/j.devcel.2010.12.004

PMCID:: PMC3028984

Abstract Article PDF–1.8M

Select item 189999716.

An Activating Mutation in sos-1 Identifies Its Dbl Domain as a Critical Inhibitor of the Epidermal Growth Factor Receptor Pathway during Caenorhabditis elegans Vulval Development

Katarzyna Modzelewska, Marc G. Elgort, Jingyu Huang, Gregg Jongeward, Amara Lauritzen, Charles H. Yoon, Paul W. Sternberg, Nadeem Moghal

Mol Cell Biol. 2007 May; 27(10): 3695–3707. Published online 2007 Mar 5. doi: 10.1128/MCB.01630-06

PMCID:: PMC1899997

Abstract Article PDF–824K

Select item 135124017.

LIP-1 phosphatase controls the extent of germline proliferation in Caenorhabditis elegans

Myon-Hee Lee, Brad Hook, Liana B Lamont, Marvin Wickens, Judith Kimble

EMBO J. 2006 Jan 11; 25(1): 88–96. Published online 2005 Dec 1. doi: 10.1038/sj.emboj.7600901

PMCID:: PMC1351240

Abstract Article PDF–300K

Select item 114255618.

The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions

Thomas A. Berset, Erika Fröhli Hoier, Alex Hajnal

Genes Dev. 2005 Jun 1; 19(11): 1328–1340. doi: 10.1101/gad.333505

PMCID:: PMC1142556

Abstract Article PDF–669K

Select item 689358519.

Gliadin Intake Causes Disruption of the Intestinal Barrier and an Increase in Germ Cell Apoptosis in A Caenorhabditis Elegans Model

Hyemin Min, Ji-Sun Kim, Jiyun Ahn, Yhong-Hee Shim

Nutrients. 2019 Nov; 11(11): 2587. Published online 2019 Oct 27. doi: 10.3390/nu11112587

PMCID:: PMC6893585

Abstract Article PDF–6.0M

Select item 979341820.

EGFR signal transduction is downregulated in C. elegans vulval precursor cells during dauer diapause

Catherine O'Keeffe, Iva Greenwald

Development. 2022 Nov 1; 149(21): dev201094. Published online 2022 Oct 31. doi: 10.1242/dev.201094

PMCID:: PMC9793418

Abstract Article

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