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Items: 1 to 20 of 39

1.
Hypothalamic ER–associated degradation regulates POMC maturation, feeding, and age-associated obesity
Geun Hyang Kim, Guojun Shi, Diane R.M. Somlo, Leena Haataja, Soobin Song, Qiaoming Long, Eduardo A. Nillni, Malcolm J. Low, Peter Arvan, Martin G. Myers, Jr., Ling Qi
J Clin Invest. 2018 Mar 1; 128(3): 1125–1140. Published online 2018 Feb 19. doi: 10.1172/JCI96420
PMCID:
PMC5824855
AbstractArticlePDF–21M
2.
Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus
Daniel G. Bichet, Yoann Lussier
J Clin Invest. 2017 Oct 2; 127(10): 3591–3593. Published online 2017 Sep 18. doi: 10.1172/JCI96839
PMCID:
PMC5617649
AbstractArticlePDF–1.8M
3.
Epithelial Sel1L is required for the maintenance of intestinal homeostasis
Shengyi Sun, Rohan Lourie, Sara B. Cohen, Yewei Ji, Julia K. Goodrich, Angela C. Poole, Ruth E. Ley, Eric Y. Denkers, Michael A. McGuckin, Qiaoming Long, Gerald E. Duhamel, Kenneth W. Simpson, Ling Qi
Mol Biol Cell. 2016 Feb 1; 27(3): 483–490. doi: 10.1091/mbc.E15-10-0724
PMCID:
PMC4751599
AbstractArticlePDF–2.1M
4.
Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway
Hanbin Jeong, Hyo Jung Sim, Eun Kyung Song, Hakbong Lee, Sung Chul Ha, Youngsoo Jun, Tae Joo Park, Changwook Lee
Sci Rep. 2016; 6: 20261. Published online 2016 Feb 9. doi: 10.1038/srep20261
PMCID:
PMC4746701
AbstractArticlePDF–2.3M
5.
Haploid Insufficiency of Suppressor Enhancer Lin12 1-like (SEL1L) Protein Predisposes Mice to High Fat Diet-induced Hyperglycemia
Adam B. Francisco, Rajni Singh, Haibo Sha, Xi Yan, Ling Qi, Xingen Lei, Qiaoming Long
J Biol Chem. 2011 Jun 24; 286(25): 22275–22282. Published online 2011 May 2. doi: 10.1074/jbc.M111.239418
PMCID:
PMC3121373
AbstractArticlePDF–1.6M
6.
mSEL-1L (Suppressor/Enhancer Lin12-like) Protein Levels Influence Murine Neural Stem Cell Self-renewal and Lineage Commitment
Marina Cardano, Giuseppe R. Diaferia, Monica Cattaneo, Sara S. Dessì, Qiaoming Long, Luciano Conti, Pasquale DeBlasio, Elena Cattaneo, Ida Biunno
J Biol Chem. 2011 May 27; 286(21): 18708–18719. Published online 2011 Mar 31. doi: 10.1074/jbc.M110.210740
PMCID:
PMC3099688
AbstractArticlePDF–3.4M
7.
SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex
Liangguang Leo Lin, Huilun Helen Wang, Brent Pederson, Xiaoqiong Wei, Mauricio Torres, You Lu, Zexin Jason Li, Xiaodan Liu, Hancheng Mao, Hui Wang, Linyao Elina Zhou, Zhen Zhao, Shengyi Sun, Ling Qi
Nat Commun. 2024; 15: 1440. Published online 2024 Feb 16. doi: 10.1038/s41467-024-45633-0
Correction in:
Nat Commun. 2024; 15: 3241.
PMCID:
PMC10873344
AbstractArticlePDF–7.3M
8.
Inflammation arising from obesity reduces taste bud abundance and inhibits renewal
Andrew Kaufman, Ezen Choo, Anna Koh, Robin Dando
PLoS Biol. 2018 Mar; 16(3): e2001959. Published online 2018 Mar 20. doi: 10.1371/journal.pbio.2001959
PMCID:
PMC5860696
AbstractArticlePDF–5.1M
9.
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival
Shengyi Sun, Guojun Shi, Xuemei Han, Adam B. Francisco, Yewei Ji, Nuno Mendonça, Xiaojing Liu, Jason W. Locasale, Kenneth W. Simpson, Gerald E. Duhamel, Sander Kersten, John R. Yates, III, Qiaoming Long, Ling Qi
Proc Natl Acad Sci U S A. 2014 Feb 4; 111(5): E582–E591. Published online 2014 Jan 22. doi: 10.1073/pnas.1318114111
Correction in:
Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16): 6115.
PMCID:
PMC3918815
AbstractArticlePDF–2.0M
10.
ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
Luis O. Correa-Medero, Shayna E. Jankowski, Hanna S. Hong, Nicholas D. Armas, Aditi I. Vijendra, Mack B. Reynolds, Garrett M. Fogo, Dominik Awad, Alexander T. Dils, Kantaro A. Inoki, Reid G. Williams, Annabelle M. Ye, Nadezhda Svezhova, Francisco Gomez-Rivera, Kathleen L. Collins, Mary X. O’Riordan, Thomas H. Sanderson, Costas A. Lyssiotis, Shannon A. Carty
Cell Rep. Author manuscript; available in PMC 2024 Jun 24.
Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114156. Published online 2024 Apr 29. doi: 10.1016/j.celrep.2024.114156
PMCID:
PMC11194752
AbstractArticlePDF–2.8M
11.
SEL1L–HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool
Yewei Ji, Yuan Luo, Yating Wu, Yao Sun, Lianfeng Zhao, Zhen Xue, Mengqi Sun, Xiaoqiong Wei, Zinan He, Shuangcheng Alivia Wu, Liangguang Leo Lin, You Lu, Lei Chang, Fei Chen, Siyu Chen, Wei Qian, Xiaoxi Xu, Shengnuo Chen, Dongli Pan, Zhangsen Zhou, Sheng Xia, Chih-Chi Andrew Hu, Tingbo Liang, Ling Qi
Nat Cell Biol. 2023; 25(5): 726–739. Published online 2023 May 4. doi: 10.1038/s41556-023-01138-4
PMCID:
PMC10185471
AbstractArticlePDF–22M
12.
SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer
Asmita Bhattacharya, Juncheng Wei, Wenxin Song, Beixue Gao, Chunyan Tian, Shuangcheng Alivia Wu, Jian Wang, Ligong Chen, Deyu Fang, Ling Qi
iScience. 2022 Oct 21; 25(10): 105183. Published online 2022 Sep 24. doi: 10.1016/j.isci.2022.105183
PMCID:
PMC9550610
AbstractArticlePDF–6.4M
13.
ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis
Guojun Shi, Diane R.M. Somlo, Geun Hyang Kim, Cristina Prescianotto-Baschong, Shengyi Sun, Nicole Beuret, Qiaoming Long, Jonas Rutishauser, Peter Arvan, Martin Spiess, Ling Qi
J Clin Invest. 2017 Oct 2; 127(10): 3897–3912. Published online 2017 Sep 18. doi: 10.1172/JCI94771
PMCID:
PMC5617659
AbstractArticlePDF–19M
14.
Integration of ER protein quality control mechanisms defines β cell function and ER architecture
Neha Shrestha, Mauricio Torres, Jason Zhang, You Lu, Leena Haataja, Rachel B. Reinert, Jeffrey Knupp, Yu-Jie Chen, Gunes Parlakgul, Ana Paula Arruda, Billy Tsai, Peter Arvan, Ling Qi
J Clin Invest. 2023 Jan 3; 133(1): e163584. Published online 2023 Jan 3. doi: 10.1172/JCI163584
PMCID:
PMC9797341
AbstractArticlePDF–5.5M
15.
Hepatic Sel1L‐Hrd1 ER‐associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH
Asmita Bhattacharya, Shengyi Sun, Heting Wang, Ming Liu, Qiaoming Long, Lei Yin, Sander Kersten, Kezhong Zhang, Ling Qi
EMBO J. 2018 Nov 15; 37(22): e99277. Published online 2018 Nov 2. doi: 10.15252/embj.201899277
PMCID:
PMC6236331
AbstractArticlePDF–4.1M
16.
The Sel1L-Hrd1 endoplasmic reticulum-associated degradation complex manages a key checkpoint in B cell development
Yewei Ji, Hana Kim, Liu Yang, Haibo Sha, Christopher A. Roman, Qiaoming Long, Ling Qi
Cell Rep. Author manuscript; available in PMC 2016 Sep 7.
Published in final edited form as: Cell Rep. 2016 Sep 6; 16(10): 2630–2640. Published online 2016 Aug 25. doi: 10.1016/j.celrep.2016.08.003
PMCID:
PMC5014582
AbstractArticlePDF–1.3M
17.
Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
Xia Liu, Jingjing Yu, Longyong Xu, Katharine Umphred-Wilson, Fanglue Peng, Yao Ding, Brendan M Barton, Xiangdong Lv, Michael Y Zhao, Shengyi Sun, Yuning Hong, Ling Qi, Stanley Adoro, Xi Chen
eLife. 2021; 10: e69975. Published online 2021 Jul 9. doi: 10.7554/eLife.69975
PMCID:
PMC8315795
AbstractArticlePDF–3.1M
18.
Protein Quality Control Through Endoplasmic Reticulum-Associated Degradation Maintains Hematopoietic Stem Cell Identity and Niche Interactions
Longyong Xu, Xia Liu, Fanglue Peng, Weijie Zhang, Liting Zheng, Yao Ding, Tianpeng Gu, Kaosheng Lv, Jin Wang, Laura Ortinau, Tianyuan Hu, Xiangguo Shi, Guojun Shi, Ge Shang, Shengyi Sun, Takao Iwawaki, Yewei Ji, Wei Li, Jeffrey M. Rosen, Xiang H.-F. Zhang, Dongsu Park, Stanley Adoro, Andre Catic, Wei Tong, Ling Qi, Daisuke Nakada, Xi Chen
Nat Cell Biol. Author manuscript; available in PMC 2021 Mar 21.
Published in final edited form as: Nat Cell Biol. 2020 Oct; 22(10): 1162–1169. Published online 2020 Sep 21. doi: 10.1038/s41556-020-00581-x
PMCID:
PMC7888538
AbstractArticlePDF–2.7M
19.
ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity
Lu Liu, Ayaka Inoki, Kelly Fan, Fengbiao Mao, Guojun Shi, Xi Jin, Meiling Zhao, Gina Ney, Morgan Jones, Shengyi Sun, Yali Dou, Ken Inoki, Ling Qi, Qing Li
Blood. 2020 Dec 24; 136(26): 2975–2986. Prepublished online 2020 Nov 4. doi: 10.1182/blood.2020007975
PMCID:
PMC7770563
AbstractArticle
20.
The ER-Associated Degradation Adaptor Protein Sel1L Regulates LPL Secretion and Lipid Metabolism
Haibo Sha, Shengyi Sun, Adams Francisco, Nicole Ehrhardt, Zhen Xue, Lei Liu, Peter Lawrence, Frits Mattijssen, Robert Guber, Muhammad S. Panhwar, J. Thomas Brenna, Hang Shi, Bingzhong Xue, Sander Kersten, André Bensadoun, Miklós Péterfy, Qiaoming Long, Ling Qi
Cell Metab. Author manuscript; available in PMC 2015 Sep 2.
Published in final edited form as: Cell Metab. 2014 Sep 2; 20(3): 458–470. Published online 2014 Jul 24. doi: 10.1016/j.cmet.2014.06.015
PMCID:
PMC4156539
AbstractArticlePDF–1.7M

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