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Select item 110568431.

Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3⁺ Regulatory T Cells

Yujian H. Yang, Roman Istomine, Fernando Alvarez, Tho-Alfakar Al-Aubodah, Xiang Qun Shi, Tomoko Takano, Angela M. Thornton, Ethan M. Shevach, Ji Zhang, Ciriaco A. Piccirillo

Cell Rep. Author manuscript; available in PMC 2024 Apr 29.

Published in final edited form as: Cell Rep. 2020 Feb 4; 30(5): 1515–1529.e4. doi: 10.1016/j.celrep.2020.01.002

PMCID:: PMC11056843

Abstract Article PDF–2.6M

Select item 110080562.

SGK1 is essential for meiotic resumption in mammalian oocytes

Edgar del Llano, Rajan Iyyappan, Daria Aleshkina, Tomas Masek, Michal Dvoran, Zongliang Jiang, Martin Pospisek, Michal Kubelka, Andrej Susor

Eur J Cell Biol. Author manuscript; available in PMC 2024 Apr 11.

Published in final edited form as: Eur J Cell Biol. 2022 Apr; 101(2): 151210. Published online 2022 Feb 25. doi: 10.1016/j.ejcb.2022.151210

PMCID:: PMC11008056

Abstract Article PDF–945K

Select item 100659853.

mTORC2 regulates CD8⁺ effector and memory T cell differentiation through serum and glucocorticoid kinase 1 (SGK1)

Chirag H. Patel, Emily B. Heikamp, Wei Xu, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Ada J. Tam, Richard L. Blosser, Jonathan D. Powell

J Immunol. Author manuscript; available in PMC 2023 Dec 15.

Published in final edited form as: J Immunol. 2022 Dec 15; 209(12): 2287–2291. doi: 10.4049/jimmunol.2100669

PMCID:: PMC10065985

Abstract Article PDF–1.1M

Select item 99267124.

Hepatocyte SGK1 activated by hepatic ischemia-reperfusion promotes the recurrence of liver metastasis via IL-6/STAT3

Xiangdong Li, Ziyi Wang, Chenyu Jiao, Yu Zhang, Nan Xia, Wenjie Yu, Xuejiao Chen, Likalamu Pascalia Wikana, Yue Liu, Linfeng Sun, Minhao Chen, Yuhao Xiao, Yuhua Shi, Sheng Han, Liyong Pu

J Transl Med. 2023; 21: 121. Published online 2023 Feb 14. doi: 10.1186/s12967-023-03977-z

PMCID:: PMC9926712

Abstract Article PDF–12M

Select item 89735855.

Columbianetin alleviates lipopolysaccharides (LPS)-induced inflammation and apoptosis in chondrocyte through activation of autophagy by inhibiting serum and glucocorticoid-induced protein kinase 1 (SGK1) expression

Wei Chen, Haotian Zheng, Xuan Zhang, Yude Xu, Zhibin Fu, Xing Ji, Changhao Wei, Guoyao An, Mingyuan Tan, Mingwang Zhou

Bioengineered. 2022; 13(2): 4051–4062. Published online 2022 Feb 7. doi: 10.1080/21655979.2022.2032970

PMCID:: PMC8973585

Abstract Article PDF–2.7M

Select item 88055836.

Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy

Shujing Zhang, Yingchao Wang, Min Yu, Ye Shang, Yanxu Chang, Hong Zhao, Yu Kang, Lu Zhao, Lei Xu, Xiaoping Zhao, Dario Difrancesco, Mirko Baruscotti, Yi Wang

Adv Sci (Weinh) 2022 Jan; 9(2): 2101485. Published online 2021 Nov 10. doi: 10.1002/advs.202101485

PMCID:: PMC8805583

Abstract Article PDF–8.6M

Select item 75560727.

Lack of PPARβ/δ-Inactivated SGK-1 Is Implicated in Liver Carcinogenesis

Bo Shen, Aimin Li, Yu-Jui Yvonne Wan, Guijia Shen, Jinshui Zhu, Yuqiang Nie

Biomed Res Int. 2020; 2020: 9563851. Published online 2020 Oct 2. doi: 10.1155/2020/9563851

PMCID:: PMC7556072

Abstract Article PDF–1.6M

Select item 72329398.

Serum- and Glucocorticoid-Inducible Kinase 1 Activity Reduces Dendritic Spines in Dorsal Hippocampus

Emily E. Steffke, Deniz Kirca, Michelle S. Mazei-Robison, Alfred J. Robison

Neurosci Lett. Author manuscript; available in PMC 2021 Apr 23.

Published in final edited form as: Neurosci Lett. 2020 Apr 23; 725: 134909. Published online 2020 Mar 10. doi: 10.1016/j.neulet.2020.134909

PMCID:: PMC7232939

Abstract Article PDF–1.2M

Select item 68779609.

SGK1 Mediates Hypoxic Pulmonary Hypertension through Promoting Macrophage Infiltration and Activation

Xin Xi, Jing Zhang, Jian Wang, Yuqin Chen, Wenmei Zhang, Xiaoping Zhang, Jie Du, Guangfa Zhu

Anal Cell Pathol (Amst) 2019; 2019: 3013765. Published online 2019 Nov 13. doi: 10.1155/2019/3013765

PMCID:: PMC6877960

Abstract Article PDF–1.1M

Select item 638243610.

p38MAPK/SGK1 signaling regulates macrophage polarization in experimental autoimmune encephalomyelitis

Bo Li, Tian-Bi Tan, Liang Wang, Xiao-Yun Zhao, Guo-Jun Tan

Aging (Albany NY) 2019 Feb 15; 11(3): 898–907. Published online 2019 Feb 4. doi: 10.18632/aging.101786

PMCID:: PMC6382436

Abstract Article PDF–2.6M

Select item 552210711.

Mechanism of oxidative stress p38MAPK-SGK1 signaling axis in experimental autoimmune encephalomyelitis (EAE)

Liang Wang, Bin Li, Mo-Yuan Quan, Lin Li, Yuan Chen, Guo-Jun Tan, Jing Zhang, Xiao-Peng Liu, Li Guo

Oncotarget. 2017 Jun 27; 8(26): 42808–42816. Published online 2017 Apr 12. doi: 10.18632/oncotarget.17057

PMCID:: PMC5522107

Abstract Article PDF–3.7M

Select item 549936212.

A salt-sensing kinase in T lymphocytes, SGK1, drives hypertension and hypertensive end-organ damage

Allison E. Norlander, Mohamed A. Saleh, Arvind K. Pandey, Hana A. Itani, Jing Wu, Liang Xiao, Jooeun Kang, Bethany L. Dale, Slavina B. Goleva, Fanny Laroumanie, Liping Du, David G. Harrison, Meena S. Madhur

JCI Insight. 2017 Jul 6; 2(13): e92801. Published online 2017 Jul 6. doi: 10.1172/jci.insight.92801

PMCID:: PMC5499362

Abstract Article PDF–1.0M

Select item 528388413.

SGK1-dependent ENaC processing and trafficking in mice with high dietary K intake and elevated aldosterone

Lei Yang, Gustavo Frindt, Florian Lang, Dietmar Kuhl, Volker Vallon, Lawrence G. Palmer

Am J Physiol Renal Physiol. 2017 Jan 1; 312(1): F65–F76. Published online 2016 Jul 13. doi: 10.1152/ajprenal.00257.2016

PMCID:: PMC5283884

Abstract Article

Select item 500527914.

Renal tubular SGK1 deficiency causes impaired K⁺ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC

Lama Al-Qusairi, Denis Basquin, Ankita Roy, Matteo Stifanelli, Renuga Devi Rajaram, Anne Debonneville, Izabela Nita, Marc Maillard, Johannes Loffing, Arohan R. Subramanya, Olivier Staub

Am J Physiol Renal Physiol. 2016 Aug 1; 311(2): F330–F342. Published online 2016 Mar 23. doi: 10.1152/ajprenal.00002.2016

PMCID:: PMC5005279

Abstract Article

Select item 500465815.

Serum Glucocorticoid–Regulated Kinase 1 Blocks CKD–Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3

Jinlong Luo, Anlin Liang, Ming Liang, Ruohan Xia, Yasmeen Rizvi, Yun Wang, Jizhong Cheng

J Am Soc Nephrol. 2016 Sep; 27(9): 2797–2808. Published online 2016 Feb 15. doi: 10.1681/ASN.2015080867

PMCID:: PMC5004658

Abstract Article

Select item 498796216.

SGK1 Activity is Modulated by Resistin in Vascular Smooth Muscle Cells and in the Aorta in Response to Diet-Induced Obesity

Takara A. Scott, Oguljahan Babayeva, Saswati Banerjee, Wei Zhong, Sharon C. Francis

Obesity (Silver Spring) Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Obesity (Silver Spring). 2016 Mar; 24(3): 678–686. Published online 2016 Feb 1. doi: 10.1002/oby.21425

PMCID:: PMC4987962

Abstract Article PDF–1.4M

Select item 430203817.

Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area

Elizabeth A. Heller, Sophia Kaska, Barbara Fallon, Deveroux Ferguson, Pamela J. Kennedy, Rachael L. Neve, Eric J. Nestler, Michelle S. Mazei-Robison

J Neurochem. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: J Neurochem. 2015 Jan; 132(2): 243–253. Published online 2014 Aug 26. doi: 10.1111/jnc.12925

PMCID:: PMC4302038

Abstract Article PDF–2.0M

Select item 399940018.

Stimulation of Ca²⁺-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1)

Anja Eylenstein, Eva-Maria Gehring, Nicole Heise, Ekaterina Shumilina, Sebastian Schmidt, Kalina Szteyn, Patrick Münzer, Meerim K. Nurbaeva, Melanie Eichenmüller, Leonid Tyan, Ivonne Regel, Michael Föller, Dietmar Kuhl, Jonathan Soboloff, Reinhold Penner, Florian Lang

FASEB J. 2011 Jun; 25(6): 2012–2021. doi: 10.1096/fj.10-178210

PMCID:: PMC3999400

Abstract Article

Select item 397364619.

SGK1-sensitive renal tubular glucose reabsorption in diabetes

Teresa F. Ackermann, Krishna M. Boini, Harald Völkl, Madhuri Bhandaru, Petra M. Bareiss, Lothar Just, Volker Vallon, Kerstin Amann, Dietmar Kuhl, Yuxi Feng, Hans-Peter Hammes, Florian Lang

Am J Physiol Renal Physiol. 2009 Apr; 296(4): F859–F866. doi: 10.1152/ajprenal.90238.2008