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Select item 91810351.

A Lack of GD3 Synthase Leads to Impaired Renal Expression of Connexins and Pannexin1 in St8sia1 Knockout Mice

Diana Meter, Anita Racetin, Katarina Vukojević, Marta Balog, Vedrana Ivić, Milorad Zjalić, Marija Heffer, Natalija Filipović

Int J Mol Sci. 2022 Jun; 23(11): 6237. Published online 2022 Jun 2. doi: 10.3390/ijms23116237

PMCID:: PMC9181035

Abstract Article PDF–6.9M

Select item 84603542.

Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics

Fu-Lei Tang, Jing Wang, Yutaka Itokazu, Robert K. Yu

J Neurochem. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: J Neurochem. 2021 Mar; 156(6): 819–833. Published online 2020 Aug 13. doi: 10.1111/jnc.15137

PMCID:: PMC8460354

Abstract Article PDF–945K

Select item 83635633.

Ganglioside GD3 is Up-regulated in Microglia and Regulates Phagocytosis Following Global Cerebral Ischemia

Jing Wang, Quanguang Zhang, Yujiao Lu, Yan Dong, Krishnan M. Dhandapani, Darrell W. Brann, Robert K Yu

J Neurochem. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: J Neurochem. 2021 Aug; 158(3): 737–752. Published online 2021 Jul 7. doi: 10.1111/jnc.15455

PMCID:: PMC8363563

Abstract Article PDF–4.3M

Select item 66003674.

Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging

Shoyoku Yo, Kazunori Hamamura, Yoshitaka Mishima, Kosuke Hamajima, Hironori Mori, Koichi Furukawa, Hisataka Kondo, Kenjiro Tanaka, Takuma Sato, Ken Miyazawa, Shigemi Goto, Akifumi Togari

Int J Mol Sci. 2019 Jun; 20(11): 2825. Published online 2019 Jun 10. doi: 10.3390/ijms20112825

PMCID:: PMC6600367

Abstract Article PDF–550K

Select item 55438125.

Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration

Yada Akkhawattanangkul, Panchanan Maiti, Yi Xue, Dipendra Aryal, William C. Wetsel, David Hamilton, Stephen C. Fowler, Michael P. McDonald

Genes Brain Behav. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Genes Brain Behav. 2017 Jun; 16(5): 522–536. Published online 2017 Apr 18. doi: 10.1111/gbb.12377

PMCID:: PMC5543812

Abstract Article PDF–1.5M

Select item 41996016.

Mice Lacking GD3 Synthase Display Morphological Abnormalities in the Sciatic Nerve and Neuronal Disturbances during Peripheral Nerve Regeneration

Victor Túlio Ribeiro-Resende, Tiago Araújo Gomes, Silmara de Lima, Maiara Nascimento-Lima, Michele Bargas-Rega, Marcelo Felipe Santiago, Ricardo Augusto de Melo Reis, Fernando Garcia de Mello

PLoS One. 2014; 9(10): e108919. Published online 2014 Oct 16. doi: 10.1371/journal.pone.0108919

Correction in:: PLoS One. 2015; 10(3): e0118242.

PMCID:: PMC4199601

Abstract Article PDF–6.3M

Select item 32406587.

Intracranial V. cholerae Sialidase Protects against Excitotoxic Neurodegeneration

Anandh Dhanushkodi, Michael P. McDonald

PLoS One. 2011; 6(12): e29285. Published online 2011 Dec 15. doi: 10.1371/journal.pone.0029285

PMCID:: PMC3240658

Abstract Article PDF–3.9M

Select item 84380048.

St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity

Pu Zhang, Yuki Ohkawa, Satoko Yamamoto, Hiroyuki Momota, Akira Kato, Kei Kaneko, Atsushi Natsume, Yesmin Farhana, Yuhsuke Ohmi, Tetsuya Okajima, Robiul H. Bhuiyan, Toshihiko Wakabayashi, Keiko Furukawa, Koichi Furukawa

Nagoya J Med Sci. 2021 Aug; 83(3): 535–549. doi: 10.18999/nagjms.83.3.535

PMCID:: PMC8438004

Abstract Article PDF–2.6M

Select item 84092979.

Lack of GD3 synthase (St8sia1) attenuates malignant properties of gliomas in genetically engineered mouse model

Yuki Ohkawa, Pu Zhang, Hiroyuki Momota, Akira Kato, Noboru Hashimoto, Yuhsuke Ohmi, Robiul H. Bhuiyan, Yesmin Farhana, Atsushi Natsume, Toshihiko Wakabayashi, Keiko Furukawa, Koichi Furukawa

Cancer Sci. 2021 Sep; 112(9): 3756–3768. Published online 2021 Jun 30. doi: 10.1111/cas.15032

PMCID:: PMC8409297

Abstract Article PDF–2.0M

Select item 672593910.

Overexpression of GD1a Ganglioside Sensitizes Motor Nerve Terminals to Anti-GD1a Antibody-Mediated Injury in a Model of Acute Motor Axonal Neuropathy

John A. Goodfellow, Tyrone Bowes, Kazim Sheikh, Masaaki Odaka, Susan K. Halstead, Peter D. Humphreys, Eric R. Wagner, Nobuhiro Yuki, Koichi Furukawa, Keiko Furukawa, Jaap J. Plomp, Hugh J. Willison

J Neurosci. 2005 Feb 16; 25(7): 1620–1628. doi: 10.1523/JNEUROSCI.4279-04.2005

PMCID:: PMC6725939

Abstract Article PDF–643K

Select item 460883611.

Ganglioside and Non-ganglioside Mediated Host Responses to the Mouse Polyomavirus

John You, Samantha D. O’Hara, Palanivel Velupillai, Sherry Castle, Steven Levery, Robert L. Garcea, Thomas Benjamin

PLoS Pathog. 2015 Oct; 11(10): e1005175. Published online 2015 Oct 16. doi: 10.1371/journal.ppat.1005175

PMCID:: PMC4608836

Abstract Article PDF–6.4M

Select item 460879912.

Structural and Functional Analysis of Murine Polyomavirus Capsid Proteins Establish the Determinants of Ligand Recognition and Pathogenicity

Michael H. C. Buch, A. Manuel Liaci, Samantha D. O’Hara, Robert L. Garcea, Ursula Neu, Thilo Stehle

PLoS Pathog. 2015 Oct; 11(10): e1005104. Published online 2015 Oct 16. doi: 10.1371/journal.ppat.1005104

PMCID:: PMC4608799

Abstract Article PDF–7.2M

Select item 383973613.

Interaction of ganglioside GD3 with an EGF receptor sustains the self-renewal ability of mouse neural stem cells in vitro

Jing Wang, Robert K. Yu

Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47): 19137–19142. Published online 2013 Nov 6. doi: 10.1073/pnas.1307224110

PMCID:: PMC3839736

Abstract Article PDF–1.2M

Select item 344248914.

Neuroblast migration and P2Y₁ receptor mediated calcium signalling depend on 9-O-acetyl GD3 ganglioside

Marcelo F Santiago, Eliana Scemes

ASN Neuro. 2012; 4(6): e00097. Prepublished online 2012 Aug 15. Published online 2012 Sep 11. doi: 10.1042/AN20120035

PMCID:: PMC3442489

Abstract Article PDF–4.3M

Select item 264869715.

The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice

Kay N. Greenshields, Susan K. Halstead, Femke M.P. Zitman, Simon Rinaldi, Kathryn M. Brennan, Colin O’Leary, Luke H. Chamberlain, Alistair Easton, Jennifer Roxburgh, John Pediani, Koichi Furukawa, Keiko Furukawa, Carl S. Goodyear, Jaap J. Plomp, Hugh J. Willison

J Clin Invest. 2009 Mar 2; 119(3): 595–610. Published online 2009 Feb 16. doi: 10.1172/JCI37338

PMCID:: PMC2648697

Abstract Article PDF–4.3M

Select item 1014038216.

Restoration of Adult Neurogenesis by Intranasal Administration of Gangliosides GD3 and GM1 in The Olfactory Bulb of A53T Alpha-Synuclein-Expressing Parkinson’s-Disease Model Mice

Takahiro Fuchigami, Yutaka Itokazu, John C. Morgan, Robert K. Yu

Mol Neurobiol. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Mol Neurobiol. 2023 Jun; 60(6): 3329–3344. Published online 2023 Feb 28. doi: 10.1007/s12035-023-03282-2

PMCID:: PMC10140382

Abstract Article PDF–2.1M

Select item 804148317.

Knockdown of lncRNA MIR4435-2HG and ST8SIA1 expression inhibits the proliferation, invasion and migration of prostate cancer cells in vitro and in vivo by blocking the activation of the FAK/AKT/β-catenin signaling pathway

Pengyi Xing, Ye Wang, Li Zhang, Chao Ma, Jianping Lu

Int J Mol Med. 2021 Jun; 47(6): 93. Published online 2021 Apr 1. doi: 10.3892/ijmm.2021.4926

PMCID:: PMC8041483

Abstract Article PDF–2.3M

Select item 632526918.

Glial Sulfatides and Neuronal Complex Gangliosides Are Functionally Interdependent in Maintaining Myelinating Axon Integrity

Rhona McGonigal, Jennifer A. Barrie, Denggao Yao, Mark McLaughlin, Madeleine E. Cunningham, Edward G. Rowan, Hugh J. Willison

J Neurosci. 2019 Jan 2; 39(1): 63–77. doi: 10.1523/JNEUROSCI.2095-18.2018

PMCID:: PMC6325269

Abstract Article PDF–4.0M

Select item 398685519.

Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord

Yuhsuke Ohmi, Yuki Ohkawa, Orie Tajima, Yasuo Sugiura, Keiko Furukawa, Koichi Furukawa

J Neuroinflammation. 2014; 11: 61. Published online 2014 Mar 28. doi: 10.1186/1742-2094-11-61

PMCID:: PMC3986855

Abstract Article PDF–2.4M

Select item 346331920.

Clostridium perfringens Alpha-toxin Recognizes the GM1a-TrkA Complex

Masataka Oda, Michiko Kabura, Teruhisa Takagishi, Ayaka Suzue, Kaori Tominaga, Shiori Urano, Masahiro Nagahama, Keiko Kobayashi, Keiko Furukawa, Koichi Furukawa, Jun Sakurai

J Biol Chem. 2012 Sep 21; 287(39): 33070–33079. Published online 2012 Jul 30. doi: 10.1074/jbc.M112.393801