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Select item 110765941.

Cardiac function is regulated by the sodium-dependent inhibition of the sodium-calcium exchanger NCX1

Kyle Scranton, Scott John, Marina Angelini, Federica Steccanella, Soban Umar, Rui Zhang, Joshua I. Goldhaber, Riccardo Olcese, Michela Ottolia

Nat Commun. 2024; 15: 3831. Published online 2024 May 7. doi: 10.1038/s41467-024-47850-z

PMCID:: PMC11076594

Abstract Article PDF–2.6M

Select item 102778412.

Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy

Nan Wu, Feiya Li, Weining Yang, William W. Du, Faryal Mehwish Awan, Chao Zhang, Juanjuan Lyu, Sema Misir, Kaixuan Zeng, Esra Eshaghi, Burton B. Yang

Mol Ther. 2023 Jun 7; 31(6): 1688–1704. Published online 2022 Oct 17. doi: 10.1016/j.ymthe.2022.10.005

PMCID:: PMC10277841

Abstract Article PDF–5.7M

Select item 95019553.

Higher Na⁺-Ca²⁺ Exchanger Function and Triggered Activity Contribute to Male Predisposition to Atrial Fibrillation

Simon Thibault, Valérie Long, Céline Fiset

Int J Mol Sci. 2022 Sep; 23(18): 10724. Published online 2022 Sep 14. doi: 10.3390/ijms231810724

PMCID:: PMC9501955

Abstract Article PDF–1.9M

Select item 86492744.

Acute Genetic Ablation of Cardiac Sodium/Calcium Exchange in Adult Mice: Implications for Cardiomyocyte Calcium Regulation, Cardioprotection, and Arrhythmia

Sabine Lotteau, Rui Zhang, Adina Hazan, Christina Grabar, Devina Gonzalez, Stephan Aynaszyan, Kenneth D. Philipson, Michela Ottolia, Joshua I. Goldhaber

J Am Heart Assoc. 2021 Sep 7; 10(17): e019273. Published online 2021 Sep 2. doi: 10.1161/JAHA.120.019273

PMCID:: PMC8649274

Abstract Article PDF–3.0M

Select item 78470735.

NO-induced vasodilation correlates directly with BP in smooth muscle-Na/Ca exchanger-1-engineered mice: elevated BP does not attenuate endothelial function

Youhua Wang, Jin Zhang, W.Gil Wier, Ling Chen, Mordecai P. Blaustein

Am J Physiol Heart Circ Physiol. 2021 Jan 1; 320(1): H221–H237. Published online 2020 Oct 30. doi: 10.1152/ajpheart.00487.2020

PMCID:: PMC7847073

Abstract Article

Select item 73077286.

NCX1 represents an ionic Na⁺ sensing mechanism in macrophages

Patrick Neubert, Arne Homann, David Wendelborn, Anna-Lorena Bär, Luka Krampert, Maximilian Trum, Agnes Schröder, Stefan Ebner, Andrea Weichselbaum, Valentin Schatz, Peter Linz, Roland Veelken, Jonas Schulte-Schrepping, Anna C. Aschenbrenner, Thomas Quast, Christian Kurts, Sabrina Geisberger, Karl Kunzelmann, Karin Hammer, Katrina J. Binger, Jens Titze, Dominik N. Müller, Waldemar Kolanus, Joachim L. Schultze, Stefan Wagner, Jonathan Jantsch

PLoS Biol. 2020 Jun; 18(6): e3000722. Published online 2020 Jun 22. doi: 10.1371/journal.pbio.3000722

PMCID:: PMC7307728

Abstract Article PDF–3.1M

Select item 63973847.

Na⁺/Ca²⁺ exchanger overexpression in smooth muscle augments cytosolic Ca²⁺ in femoral arteries of living mice

Jin Zhang, Youhua Wang, Ling Chen, W. Gil Wier, Mordecai P. Blaustein

Am J Physiol Heart Circ Physiol. 2019 Feb 1; 316(2): H298–H310. Published online 2018 Nov 21. doi: 10.1152/ajpheart.00185.2018

Correction in:: Am J Physiol Heart Circ Physiol. 2019 Mar 1; 316(3): H762–H763.

PMCID:: PMC6397384

Abstract Article

Select item 57847568.

Triggered activity in atrial myocytes is influenced by Na⁺/Ca²⁺ exchanger activity in genetically altered mice

N. Bögeholz, P. Pauls, S. Kaese, J. S. Schulte, M. D. Lemoine, D. G. Dechering, G. Frommeyer, J. I. Goldhaber, M. D. Seidl, U. Kirchhefer, L. Eckardt, F. U. Müller, C. Pott

J Mol Cell Cardiol. Author manuscript; available in PMC 2018 Jan 25.

Published in final edited form as: J Mol Cell Cardiol. 2016 Dec; 101: 106–115. Published online 2016 Nov 9. doi: 10.1016/j.yjmcc.2016.11.004

PMCID:: PMC5784756

Article PDF–1.1M

Select item 55752989.

The Role of Na+/Ca2+ Exchanger 1 in Maintaining Ductus Arteriosus Patency

Minghui Li, Chuan Jiang, Lincai Ye, Shoubao Wang, Haibo Zhang, Jinfen Liu, Haifa Hong

Sci Rep. 2017; 7: 9826. Published online 2017 Aug 29. doi: 10.1038/s41598-017-10377-z

PMCID:: PMC5575298

Abstract Article PDF–2.8M

Select item 469511710.

Na⁺-induced Ca²⁺ influx through reverse mode of Na⁺-Ca²⁺ exchanger in mouse ventricular cardiomyocyte

Zhen-Yu Yan, Tao Ban, Yao Fan, Wei-Ran Chen, Hong-Li Sun, Hanying Chen, Quo-Fen Qiao, Bai-Yan Li

Oncotarget. 2015 Sep 15; 6(27): 23272–23280. Published online 2015 Aug 6. doi: 10.18632/oncotarget.4878

PMCID:: PMC4695117

Abstract Article PDF–4.6M

Select item 451310211.

Endothelial Angiogenesis and Barrier Function in Response to Thrombin Require Ca²⁺ Influx through the Na⁺/Ca²⁺ Exchanger

Petros Andrikopoulos, Julius Kieswich, Steven M. Harwood, Akemichi Baba, Toshio Matsuda, Olivier Barbeau, Keith Jones, Suzanne A. Eccles, Muhammad M. Yaqoob

J Biol Chem. 2015 Jul 24; 290(30): 18412–18428. Published online 2015 May 15. doi: 10.1074/jbc.M114.628156

PMCID:: PMC4513102

Abstract Article PDF–2.5M

Select item 438774212.

Conditional knockout of smooth muscle sodium calcium exchanger type‐1 lowers blood pressure and attenuates Angiotensin II‐salt hypertension

Youhua Wang, Ling Chen, Meng Li, Helen Cha, Takahiro Iwamoto, Jin Zhang

Physiol Rep. 2015 Jan; 3(1): e12273. Published online 2015 Jan 27. doi: 10.14814/phy2.12273

PMCID:: PMC4387742

Abstract Article PDF–1.4M

Select item 383676913.

Complete Atrial-Specific Knockout of Sodium-Calcium Exchange Eliminates Sinoatrial Node Pacemaker Activity

Sabine Groenke, Eric D. Larson, Sarah Alber, Rui Zhang, Scott T. Lamp, Xiaoyan Ren, Haruko Nakano, Maria C. Jordan, Hrayr S. Karagueuzian, Kenneth P. Roos, Atsushi Nakano, Catherine Proenza, Kenneth D. Philipson, Joshua I. Goldhaber

PLoS One. 2013; 8(11): e81633. Published online 2013 Nov 21. doi: 10.1371/journal.pone.0081633

PMCID:: PMC3836769

Abstract Article PDF–664K

Select item 350008714.

Proarrhythmia in a non-failing murine model of cardiac-specific Na⁺/Ca²⁺ exchanger overexpression: whole heart and cellular mechanisms

Christian Pott, Adam Muszynski, Matthias Ruhe, N. Bögeholz, Jan S. Schulte, Peter Milberg, Gerold Mönnig, Larissa Fabritz, Joshua I. Goldhaber, Günter Breithardt, Wilhelm Schmitz, Kenneth D. Philipson, Lars Eckardt, Paulus Kirchhof, Frank U. Müller

Basic Res Cardiol. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Basic Res Cardiol. 2012 Mar; 107(2): 247. Published online 2012 Feb 11. doi: 10.1007/s00395-012-0247-7

PMCID:: PMC3500087

Abstract Article PDF–1.1M

Select item 338293015.

Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence

Momoko Yoshimoto, Prashanth Porayette, Nicole L. Glosson, Simon J. Conway, Nadia Carlesso, Angelo A. Cardoso, Mark H. Kaplan, Mervin C. Yoder

Blood. 2012 Jun 14; 119(24): 5706–5714. Prepublished online 2012 Mar 19. doi: 10.1182/blood-2011-12-397489

PMCID:: PMC3382930

Abstract Article

Select item 317454616.

Attenuated renal vascular responses to acute angiotensin II infusion in smooth muscle-specific Na⁺/Ca²⁺ exchanger knockout mice

Di Zhao, Jin Zhang, Mordecai P. Blaustein, L. Gabriel Navar

Am J Physiol Renal Physiol. 2011 Sep; 301(3): F574–F579. Published online 2011 Jun 22. doi: 10.1152/ajprenal.00065.2011

PMCID:: PMC3174546

Abstract Article

Select item 314208117.

Heterozygous Inactivation of the Na/Ca Exchanger Increases Glucose-Induced Insulin Release, β-Cell Proliferation, and Mass

Evrard Nguidjoe, Sophie Sokolow, Serge Bigabwa, Nathalie Pachera, Eva D'Amico, Florent Allagnat, Jean-Marie Vanderwinden, Abdullah Sener, Mario Manto, Marianne Depreter, Jan Mast, Geraldine Joanny, Eduard Montanya, Jacques Rahier, Alessandra K. Cardozo, Décio L. Eizirik, Stéphane Schurmans, André Herchuelz

Diabetes. 2011 Aug; 60(8): 2076–2085. Published online 2011 Jul 18. doi: 10.2337/db10-0924

PMCID:: PMC3142081

Abstract Article PDF–1.6M

Select item 312187418.

Generation of Novel Reporter Stem Cells and Their Application for Molecular Imaging of Cardiac-Differentiated Stem Cells In Vivo

Ramana K. Kammili, David G. Taylor, Jixiang Xia, Kingsley Osuala, Kellie Thompson, Donald R. Menick, Steven N. Ebert

Stem Cells Dev. 2010 Sep; 19(9): 1437–1448. Published online 2010 Jan 28. doi: 10.1089/scd.2009.0308

PMCID:: PMC3121874

Abstract Article PDF–1.4M

Select item 302976419.

Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential

Momoko Yoshimoto, Encarnacion Montecino-Rodriguez, Michael J. Ferkowicz, Prashanth Porayette, W. Christopher Shelley, Simon J. Conway, Kenneth Dorshkind, Mervin C. Yoder

Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4): 1468–1473. Published online 2011 Jan 5. doi: 10.1073/pnas.1015841108

PMCID:: PMC3029764

Abstract Article PDF–844K

Select item 297602120.

Activation of reverse Na⁺–Ca²⁺ exchange by the Na⁺ current augments the cardiac Ca²⁺ transient: evidence from NCX knockout mice

Robert Larbig, Natalia Torres, John H B Bridge, Joshua I Goldhaber, Kenneth D Philipson

J Physiol. 2010 Sep 1; 588(Pt 17): 3267–3276. Published online 2010 Jul 19. doi: 10.1113/jphysiol.2010.187708

PMCID:: PMC2976021

Abstract Article PDF–469K

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